DE69933216D1 - Erythropoietin-analog-menschliches serum-albumin fusionsprotein - Google Patents

Erythropoietin-analog-menschliches serum-albumin fusionsprotein

Info

Publication number
DE69933216D1
DE69933216D1 DE69933216T DE69933216T DE69933216D1 DE 69933216 D1 DE69933216 D1 DE 69933216D1 DE 69933216 T DE69933216 T DE 69933216T DE 69933216 T DE69933216 T DE 69933216T DE 69933216 D1 DE69933216 D1 DE 69933216D1
Authority
DE
Germany
Prior art keywords
fusion protein
serum albumin
human serum
albumin fusion
erythropoietin analog
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69933216T
Other languages
English (en)
Other versions
DE69933216T2 (de
Inventor
W Young
M Meade
M Krane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
rEVO Biologics Inc
Original Assignee
GTC Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GTC Biotherapeutics Inc filed Critical GTC Biotherapeutics Inc
Publication of DE69933216D1 publication Critical patent/DE69933216D1/de
Application granted granted Critical
Publication of DE69933216T2 publication Critical patent/DE69933216T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69933216T 1998-06-15 1999-06-15 Erythropoietin-analog-menschliches serum-albumin fusionsprotein Expired - Fee Related DE69933216T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8934398P 1998-06-15 1998-06-15
US89343P 1998-06-15
PCT/US1999/013438 WO1999066054A2 (en) 1998-06-15 1999-06-15 Erythropoietin analog-human serum albumin fusion protein

Publications (2)

Publication Number Publication Date
DE69933216D1 true DE69933216D1 (de) 2006-10-26
DE69933216T2 DE69933216T2 (de) 2007-09-20

Family

ID=22217149

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69933216T Expired - Fee Related DE69933216T2 (de) 1998-06-15 1999-06-15 Erythropoietin-analog-menschliches serum-albumin fusionsprotein

Country Status (11)

Country Link
US (4) US6548653B1 (de)
EP (1) EP1088084B1 (de)
JP (1) JP4087563B2 (de)
AT (1) ATE339507T1 (de)
AU (1) AU775422B2 (de)
CA (1) CA2330527A1 (de)
DE (1) DE69933216T2 (de)
DK (1) DK1088084T3 (de)
ES (1) ES2273497T3 (de)
HK (1) HK1036475A1 (de)
WO (1) WO1999066054A2 (de)

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US20020155998A1 (en) 2002-10-24
ES2273497T3 (es) 2007-05-01
DK1088084T3 (da) 2007-01-29
DE69933216T2 (de) 2007-09-20
US7101971B2 (en) 2006-09-05
CA2330527A1 (en) 1999-12-23
US20050158832A1 (en) 2005-07-21
HK1036475A1 (en) 2002-01-04
ATE339507T1 (de) 2006-10-15
US20040143857A1 (en) 2004-07-22
EP1088084B1 (de) 2006-09-13
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