EE03424B1 - Allergiavastase valguhüdrolüsaadipreparaadi valmistamise meetod - Google Patents

Allergiavastase valguhüdrolüsaadipreparaadi valmistamise meetod

Info

Publication number
EE03424B1
EE03424B1 EE9700339A EE9700339A EE03424B1 EE 03424 B1 EE03424 B1 EE 03424B1 EE 9700339 A EE9700339 A EE 9700339A EE 9700339 A EE9700339 A EE 9700339A EE 03424 B1 EE03424 B1 EE 03424B1
Authority
EE
Estonia
Prior art keywords
preparation
protein hydrolyzate
allergy protein
formulation
hydrolyzate formulation
Prior art date
Application number
EE9700339A
Other languages
English (en)
Other versions
EE9700339A (et
Inventor
Isolauri Erika
Mets�niitty Leena
Korhonen Hannu
Salminen Seppo
Syv�oja Eeva-Liisa
Original Assignee
Valio Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8543602&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE03424(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Valio Oy filed Critical Valio Oy
Publication of EE9700339A publication Critical patent/EE9700339A/et
Publication of EE03424B1 publication Critical patent/EE03424B1/et

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A23J3/341—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
    • A23J3/343—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins
    • A23J3/344—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins of dairy proteins of casein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Dairy Products (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EE9700339A 1995-06-14 1996-06-12 Allergiavastase valguhüdrolüsaadipreparaadi valmistamise meetod EE03424B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI952926A FI104465B (fi) 1995-06-14 1995-06-14 Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö
PCT/FI1996/000350 WO1997000078A1 (en) 1995-06-14 1996-06-12 Methods of preventing or treating allergies

Publications (2)

Publication Number Publication Date
EE9700339A EE9700339A (et) 1998-06-15
EE03424B1 true EE03424B1 (et) 2001-06-15

Family

ID=8543602

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9700339A EE03424B1 (et) 1995-06-14 1996-06-12 Allergiavastase valguhüdrolüsaadipreparaadi valmistamise meetod

Country Status (26)

Country Link
US (2) US6506380B1 (et)
EP (1) EP0833649B2 (et)
JP (1) JP3983804B2 (et)
KR (1) KR100494741B1 (et)
CN (1) CN1154506C (et)
AR (1) AR003960A1 (et)
AT (1) ATE230606T1 (et)
BG (1) BG63153B1 (et)
BR (1) BR9607827A (et)
CA (1) CA2224320C (et)
CZ (1) CZ291904B6 (et)
DE (1) DE69625690T3 (et)
DK (1) DK0833649T4 (et)
EE (1) EE03424B1 (et)
ES (1) ES2191103T5 (et)
FI (1) FI104465B (et)
IL (1) IL122577A0 (et)
MX (1) MX9710109A (et)
MY (1) MY113912A (et)
NO (1) NO321504B1 (et)
NZ (1) NZ310478A (et)
PL (1) PL185123B1 (et)
RO (1) RO120243B1 (et)
SK (1) SK284245B6 (et)
WO (1) WO1997000078A1 (et)
ZA (1) ZA965088B (et)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012126481A1 (en) 2011-02-25 2012-09-27 OÜ Tervisliku Piima Biotehnoloogiate Arenduskeskus Isolated microorganism strains lactobacillus plantarum mcc1 dsm 23881 and lactobacillus gasseri mcc2 dsm 23882 and their use

Families Citing this family (165)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI104465B (fi) * 1995-06-14 2000-02-15 Valio Oy Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö
PT986314E (pt) * 1997-06-03 2008-12-30 Ganeden Biotech Inc Bactéria láctica probiótica para tratar infecções bacterianas associadas à sids
AU3210100A (en) 1999-01-19 2000-08-01 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
WO2001010453A2 (en) 1999-08-05 2001-02-15 Societe Des Produits Nestle S.A. Bifidobacteria capable of preventing diarrhea
AU6160200A (en) 1999-08-05 2001-03-05 Societe Des Produits Nestle S.A. New bifidobacteria preventing diarrhea caused by pathogenic bacteria
WO2001057534A2 (en) * 2000-02-04 2001-08-09 Bioseek Compositions and methods for reducing autoimmunity
FI110668B (fi) * 2000-06-20 2003-03-14 Aboatech Ab Oy Probioottien käyttö atooppisten sairauksien primaariseen ehkäisyyn
JP2004514424A (ja) 2000-09-25 2004-05-20 ソシエテ　デ　プロデユイ　ネツスル　ソシエテ　アノニム アレルギー反応を起こす個人の傾向を減少させることができる乳酸菌
MXPA03002957A (es) 2000-10-06 2005-06-30 Nestle Sa Uso de bacteria probiotica de acido lactico para balancear el sistema inmune de la piel.
FI109602B (fi) * 2001-01-25 2002-09-13 Valio Oy Probioottiyhdistelmä
EP1228707A1 (en) * 2001-02-01 2002-08-07 Campina Melkunie B.V. Use of alpha-lactalbumin as prebiotic agent
MXPA03007802A (es) * 2001-03-09 2003-12-08 Nestle Sa Composicion que mejora las deficiencias fisiologicas relacionadas con la edad y que incrementa la longevidad.
JP2003137804A (ja) * 2001-10-31 2003-05-14 Morinaga Milk Ind Co Ltd インターロイキン−１８誘導剤
EP1364586A1 (en) * 2002-05-24 2003-11-26 Nestec S.A. Probiotics and oral tolerance
EP1509609B1 (en) 2002-06-04 2015-04-22 DSM IP Assets B.V. Protein hydrolysate rich in tripeptides
WO2004003235A2 (en) 2002-06-28 2004-01-08 Puleva Biotech, S.A. Probiotic strains, a process for the selection of them, compositions thereof, and their use
EP1384483A1 (en) 2002-07-23 2004-01-28 Nestec S.A. Probiotics for treatment of irritable bowel disease (IBS) through improvement of gut neuromuscular function
US7105336B2 (en) * 2002-10-07 2006-09-12 Biogaia Ab Selection and use of lactic acid bacteria for reducing inflammation caused by Helicobacter
US20040208863A1 (en) * 2003-01-30 2004-10-21 James Versalovic Anti-inflammatory activity from lactic acid bacteria
CN1863463B (zh) 2003-06-23 2011-05-04 雀巢技术公司 用于促进肠道屏障成熟的营养组合物
US7208474B2 (en) 2004-02-25 2007-04-24 Pioneer Hi-Bred International, Inc. Bacillus thuringiensis crystal polypeptides, polynucleotides, and compositions thereof
US20050265946A1 (en) * 2004-05-28 2005-12-01 Kao Corporation Elastase inhibitor
US7862808B2 (en) * 2004-07-01 2011-01-04 Mead Johnson Nutrition Company Method for preventing or treating respiratory infections and acute otitis media in infants using Lactobacillus rhamnosus LGG and Bifidobacterium lactis Bb-12
RU2428886C2 (ru) 2005-04-13 2011-09-20 Нестек С.А. Смесь для грудных детей, содержащая пробиотики
US20060233762A1 (en) * 2005-04-15 2006-10-19 Mcmahon Robert J Method for treating or preventing systemic inflammation in formula-fed infants
US7303745B2 (en) 2005-04-15 2007-12-04 Bristol-Myers Squibb Company Method for preventing or treating the development of respiratory allergies
TW200735781A (en) * 2005-11-14 2007-10-01 Nestec Sa Food product
PL1986669T3 (pl) 2006-02-15 2012-09-28 Nestec Sa Zastosowanie Bifidobacterium longum do zapobiegania i leczenia zapalenia
ES2553636T3 (es) 2006-03-07 2015-12-10 Nestec S.A. Mezcla simbiótica
ES2403644T3 (es) * 2006-06-15 2013-05-20 Nestec S.A. Inducción de tolerancia a las proteínas de huevo
WO2008106373A1 (en) * 2007-02-28 2008-09-04 Mead Johnson Nutrition Company Product containing inactivated probiotic for children or infants
EP1974734A1 (en) † 2007-03-28 2008-10-01 Nestec S.A. Probiotics for reduction of risk of obesity
CN101273736B (zh) * 2007-03-28 2012-08-08 北京弗蒙特生物技术有限公司 一种在常温下保持高活菌数的发酵乳的制备方法
EP1974735A1 (en) 2007-03-28 2008-10-01 Nestec S.A. Reduction of risk of diarrhoea
EP1974743A1 (en) 2007-03-28 2008-10-01 Nestec S.A. Probiotics to Improve Gut Microbiota
EP2195443B1 (en) 2007-08-24 2015-01-07 Codexis, Inc. Improved ketoreductase polypeptides for the stereoselective production of (r)-3-hydroxythiolane
EP2072052A1 (en) 2007-12-17 2009-06-24 Nestec S.A. Prevention of opportunistic infections in immune-compromised subjects
AU2009207823B2 (en) 2008-01-24 2015-02-19 Société des Produits Nestlé S.A. Capsule containing nutritional ingredients and method of delivery of a nutritional liquid from the capsule
EP3097927B1 (en) 2008-02-01 2023-05-03 Murdoch Childrens Research Institute A method of inducing tolerance to an allergen
RU2495927C2 (ru) 2008-03-14 2013-10-20 Нестек С.А. Синбиотическая смесь
EP2127661A1 (en) 2008-05-27 2009-12-02 Nestec S.A. Probiotics to improve gut microbiotica
CA2726850C (en) 2008-06-13 2015-06-02 Codexis, Inc. Method of synthesizing polynucleotide variants
US20090312196A1 (en) 2008-06-13 2009-12-17 Codexis, Inc. Method of synthesizing polynucleotide variants
MX2010014500A (es) 2008-06-24 2011-05-30 Codexis Inc Procedimientos biocataliticos para la preparacion de compuestos de prolina biciclica fusionada sustancialmente estereomericamente puros.
EP2147678A1 (en) 2008-07-21 2010-01-27 Nestec S.A. Probiotics to increase IgA secretion in infants born by caesarean section
RU2392001C2 (ru) * 2008-08-04 2010-06-20 Государственное образовательное учреждение высшего профессионального образования "Нижегородская государственная медицинская академия Федерального агентства по здравоохранению и социальному развитию" Способ лечения желтушных форм вирусного гепатита а у детей с пищевой аллергией
ES2560459T3 (es) 2008-08-27 2016-02-19 Codexis, Inc. Polipéptidos cetorreductasa para la producción de una 3-aril-3-hidroxipropanamina a partir de una 3-aril-3-cetopropanamina
DK2385983T3 (en) 2009-01-08 2018-02-12 Codexis Inc Transaminase POLYPEPTIDES
WO2010107644A2 (en) 2009-03-17 2010-09-23 Codexis, Inc. Variant endoglucanases and related polynucleotides
CN102428170B (zh) 2009-03-31 2015-03-18 科德克希思公司 改良的内切葡聚糖酶
US8357523B2 (en) 2009-06-16 2013-01-22 Codexis, Inc. Beta-glucosidase variant enzymes and related polynucleotides
HUE055413T2 (hu) 2009-06-22 2021-11-29 Codexis Inc Ketoreduktáz-közvetített sztereoszelektív útvonal alfa-klóralkoholokhoz
WO2011011630A2 (en) 2009-07-23 2011-01-27 Codexis, Inc. Nitrilase biocatalysts
WO2011020780A1 (en) * 2009-08-18 2011-02-24 Nestec S.A. A nutritional composition comprising lactococcus strains and reducing allergy symptoms, especially in infants and children.
US9439449B2 (en) * 2009-08-18 2016-09-13 Nestec S.A. Nutritional composition comprising Bifidobacterium longum strains and reducing food allergy symptoms, especially in infants and children
SG178456A1 (en) 2009-08-19 2012-04-27 Codexis Inc Ketoreductase polypeptides for the preparation of phenylephrine
US8785170B2 (en) 2009-09-04 2014-07-22 Codexis, Inc. Variant CBH2 cellulases and related polynucleotides
EP2295535A1 (en) * 2009-09-11 2011-03-16 Mead Johnson Nutrition Company Probiotic material
DK2478137T3 (da) 2009-09-18 2017-11-27 Codexis Inc Reduceret kodonmutagenese
US8143050B2 (en) 2009-11-25 2012-03-27 Codexis, Inc. Recombinant β-glucosidase variants for production of soluble sugars from cellulosic biomass
BR112012012192A2 (pt) 2009-11-25 2017-07-04 Codexis Inc b-glicosidades variantes recombinantes thermoascus aurantiacus para produção de açúcares fermentáveis a partir da biomassa celulósica
WO2011069987A1 (en) 2009-12-08 2011-06-16 Nestec S.A. Infant formula with probiotics and milk fat globule membrane components
SG181535A1 (en) 2009-12-08 2012-07-30 Codexis Inc Synthesis of prazole compounds
CA2786001A1 (en) 2009-12-31 2011-07-07 Pioneer Hi-Bred International, Inc. Engineering plant resistance to diseases caused by pathogens
WO2011140219A1 (en) 2010-05-04 2011-11-10 Codexis, Inc. Biocatalysts for ezetimibe synthesis
WO2011143274A1 (en) 2010-05-10 2011-11-17 Perseid Therapeutics Polypeptide inhibitors of vla4
WO2011150313A1 (en) 2010-05-28 2011-12-01 Codexis, Inc. Pentose fermentation by a recombinant microorganism
HUE038434T2 (hu) 2010-06-17 2018-10-29 Codexis Inc Biokatalizátorok és módszerek (S)-3(1-aminoetil)-fenol szintéziséhez
BR112012033361A2 (pt) 2010-06-28 2020-10-20 Codexis, Inc. acul-redutases formadoras de álcoois graxos (fars) e seus modos de uso.
AU2011272878B2 (en) 2010-06-30 2015-04-23 Codexis, Inc. Highly stable beta-class carbonic anhydrases useful in carbon capture systems
EP2605772B1 (en) 2010-08-16 2016-06-22 Cardiome International AG Process for preparing aminocyclohexyl ether compounds
US9493802B2 (en) 2010-08-20 2016-11-15 Codexis, Inc. Use of glycohydrolase 61 protein variants with improved thermostability for processing cellulose
WO2012078800A2 (en) 2010-12-08 2012-06-14 Codexis, Inc. Biocatalysts and methods for the synthesis of armodafinil
WO2012135110A1 (en) 2011-03-30 2012-10-04 Codexis, Inc. Pentose fermentation by a recombinant microorganism
HUE038800T2 (hu) 2011-04-13 2018-11-28 Codexis Inc Biokatalitikus eljárás eszlikarbazepin és ennek analógjai elõállítására
UA111078C2 (uk) * 2011-05-03 2016-03-25 Нестек С.А. Гідролізат білкового субстрату і спосіб його виготовлення
WO2013003219A1 (en) 2011-06-30 2013-01-03 Codexis, Inc. Pentose fermentation by a recombinant microorganism
BR112014004171A2 (pt) 2011-08-22 2018-11-06 Codexis Inc variantes da proteína glicósideo hidrolase gh61 e cofatores que aumentam a atividade de gh61
US9109209B2 (en) 2011-09-08 2015-08-18 Codexis, Inc. Biocatalysts and methods for the synthesis of substituted lactams
WO2013048661A1 (en) 2011-09-30 2013-04-04 Codexis, Inc. Fungal proteases
WO2013052101A1 (en) * 2011-10-03 2013-04-11 Kelly Foods Corporation Probiotic composition for pets and method of providing the same
US20130089638A1 (en) * 2011-10-11 2013-04-11 Mead Johnson Nutrition Company Compositions Comprising Maltotriose And Methods Of Using Same To Inhibit Damage Caused By Dehydration Processes
CN106479990B (zh) 2011-11-18 2020-09-18 科德克希思公司 用于制备羟基取代的氨基甲酸酯的生物催化剂
EP2794871A4 (en) 2011-12-20 2015-12-30 Codexis Inc VARIANTS OF ENDOGLUCANASE-1B (EG1B)
US20130251829A1 (en) * 2012-03-23 2013-09-26 Mead Johnson Nutrition Company Probiotic derived non-viable material for infection prevention and treatment
WO2013142770A1 (en) 2012-03-23 2013-09-26 Codexis, Inc. Biocatalysts and methods for synthesizing derivatives of tryptamine and tryptamine analogs
WO2013169725A2 (en) 2012-05-08 2013-11-14 Codexis, Inc. Biocatalysts and methods for hydroxylation of chemical compounds
SG11201407297VA (en) 2012-05-11 2014-12-30 Codexis Inc Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
BR112014031024A2 (pt) 2012-06-11 2017-06-27 Codexis Inc xilanases e xilosidases fúngicas.
EP2922953A4 (en) 2012-11-20 2016-11-09 Shell Int Research PENTOSEFERMENTATION BY A RECOMBINANT MICROORGANISM
WO2014088984A1 (en) 2012-12-07 2014-06-12 Merck Sharp & Dohme Corp. Biocatalytic transamination process
US9902943B2 (en) 2012-12-21 2018-02-27 Codexis, Inc. Engineered biocatalysts and methods for synthesizing chiral amines
CA2898495C (en) 2013-01-18 2021-06-01 Codexis, Inc. Engineered biocatalysts useful for carbapenem synthesis
ES2694327T3 (es) 2013-02-28 2018-12-19 Codexis, Inc. Polipéptidos de transaminasa modificados por biocatálisis industrial
CN103355405A (zh) * 2013-04-07 2013-10-23 苏州旭优食品科技有限公司 一种低过敏性含乳制品的加工工艺
MX366196B (es) 2013-04-18 2019-07-01 Codexis Inc Polipeptidos diseñados de fenilalanina amonio liasa.
US9822346B2 (en) 2013-11-13 2017-11-21 Codexis, Inc. Engineered imine reductases and methods for the reductive amination of ketone and amine compounds
HUE056444T2 (hu) 2014-04-16 2022-02-28 Codexis Inc Génmódosított tirozin-ammónia-liáz
WO2016007623A1 (en) 2014-07-09 2016-01-14 Codexis, Inc. Novel p450-bm3 variants with improved activity
DK3224354T3 (da) 2014-11-25 2021-03-01 Codexis Inc Manipulerede iminreductaser og fremgangsmåder til den reduktive aminering af keton- og aminforbindelser
MA41020A (fr) 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
US20170360900A1 (en) 2014-12-22 2017-12-21 Codexis, Inc. Human alpha-galactosidase variants
WO2016130412A1 (en) 2015-02-10 2016-08-18 Codexis, Inc. Ketoreductase polypeptides for the synthesis of chiral compounds
KR102604503B1 (ko) 2015-05-07 2023-11-20 코덱시스, 인코포레이티드 페니실린-g 아실라아제
WO2017007547A1 (en) 2015-07-07 2017-01-12 Codexis, Inc. Novel p450-bm3 variants with improved activity
EP3452587B1 (en) 2016-05-05 2021-09-08 Codexis, Inc. Penicillin-g acylases
WO2017213758A1 (en) 2016-06-09 2017-12-14 Codexis, Inc. Biocatalysts and methods for hydroxylation of chemical compounds
WO2017218325A1 (en) 2016-06-15 2017-12-21 Codexis, Inc. Engineered beta-glucosidases and glucosylation methods
JP7316662B2 (ja) 2016-08-26 2023-07-28 コデクシス， インコーポレイテッド 操作されたイミンレダクターゼ、ならびにケトン化合物およびアミン化合物の還元的アミノ化のための方法
WO2018129130A1 (en) 2017-01-05 2018-07-12 Codexis, Inc. Penicillin-g acylases
AU2018215335B2 (en) 2017-02-03 2020-10-01 Tate & Lyle Solutions Usa Llc Engineered glycosyltransferases and steviol glycoside glucosylation methods
WO2018148633A1 (en) 2017-02-13 2018-08-16 Codexis, Inc. Engineered phenylalanine ammonia lyase polypeptides
AU2018258274C1 (en) 2017-04-24 2021-12-02 Tesaro, Inc. Methods of manufacturing of niraparib
WO2018200214A2 (en) 2017-04-27 2018-11-01 Codexis, Inc. Ketoreductase polypeptides and polynucleotides
CA3062550A1 (en) 2017-05-08 2018-11-15 Codexis, Inc. Engineered ligase variants
CN111032682B (zh) 2017-06-14 2024-04-12 科德克希思公司 用于工业生物催化的工程化转氨酶多肽
EP3645713A4 (en) 2017-06-27 2021-06-30 Codexis, Inc. PENICILLIN-G ACYLASES
AU2018292105B2 (en) 2017-06-30 2024-12-12 Codexis, Inc. T7 RNA polymerase variants
RU2020103727A (ru) 2017-06-30 2021-07-30 Кодексис, Инк. Варианты рнк-полимеразы т7
EP3706780A4 (en) 2017-11-07 2021-12-22 Codexis, Inc. TRANSGLUTAMINASE VARIANTS
SG11202004185PA (en) 2017-12-13 2020-06-29 Codexis Inc Carboxyesterase polypeptides for amide coupling
EP4471137A3 (en) 2017-12-13 2025-02-19 GlaxoSmithKline Intellectual Property Development Ltd Carboxyesterase biocatalysts
US10900055B2 (en) 2018-06-12 2021-01-26 Codexis, Inc. Engineered tyrosine ammonia lyase
JP7461658B2 (ja) 2018-07-09 2024-04-04 コデクシス， インコーポレイテッド 操作されたプリンヌクレオシドホスホリラーゼバリアント酵素
AU2019300836B2 (en) 2018-07-09 2025-09-04 Codexis, Inc. Engineered deoxyribose-phosphate aldolases
MX2021000328A (es) 2018-07-09 2021-03-25 Codexis Inc Enzimas de variantes de galactosa oxidasa modificadas geneticamente.
SG11202012109UA (en) 2018-07-09 2021-01-28 Codexis Inc Engineered phosphopentomutase variant enzymes
EP3820991A4 (en) 2018-07-09 2022-07-06 Codexis, Inc. MANIPULATED ENZYMES WITH PANTOTHENATE KINASE VARIANTS
CN112672989A (zh) 2018-07-12 2021-04-16 科德克希思公司 工程化苯丙氨酸氨裂合酶多肽
BR112021001661A8 (pt) 2018-07-30 2022-08-09 Codexis Inc Glicosiltransferase modificada, polinucleotídeo modificado, vetor, célula hospedeira, métodos para produzir pelo menos uma glicosiltransferase modificada, para produzir pelo menos uma variante de sacarose sintase, para glicosilação de um substrato, para produzir rebaudiosídeo m, rebaudiosídeo a e/ou rebaudiosídeo i e rebaudiosídeo d, composição, sacarose sintase modificada, pelo menos um rebaudiosídeo, rebaudiosídeo m, rebaudiosídeo a, rebaudiosídeo i, e, rebaudiosídeo d.
KR20210084590A (ko) 2018-10-29 2021-07-07 코덱시스, 인코포레이티드 조작된 dna 중합효소 변이체
EP3893860A4 (en) 2018-12-14 2023-03-29 Codexis, Inc. ENGINEERED TYROSINE AMMONIA LYASE
US11427813B2 (en) 2018-12-20 2022-08-30 Codexis, Inc. Human alpha-galactosidase variants
EP3963057A4 (en) 2019-05-01 2023-06-14 Codexis, Inc. MANIPULATED IMINE REDUCTASES AND METHODS FOR THE REDUCTIVE AMINATION OF KETONE AND AMINE COMPOUNDS
US12215359B2 (en) 2019-05-01 2025-02-04 Codexis, Inc. Engineered glucose dehydrogenases and methods for the reductive amination of ketone and amine compounds
US12480104B2 (en) 2019-07-02 2025-11-25 Codexis, Inc. Engineered sucrose phosphorylase variant enzymes
CA3142162A1 (en) 2019-07-02 2021-01-07 Codexis, Inc. Engineered acetate kinase variant enzymes
MX2022000903A (es) 2019-07-23 2022-02-14 Frieslandcampina Nederland Bv Composicion nutricional que comprende inmunoglobulina y grasa de la leche.
US11987823B2 (en) 2019-08-30 2024-05-21 Societe Des Produits Nestle S.A. Engineered lipase variants
WO2021050348A1 (en) 2019-09-12 2021-03-18 Codexis, Inc. Peroxidase activity towards 10-acetyl-3,7-dihydroxyphenoxazine
MX2022004017A (es) 2019-10-02 2022-05-02 Abbott Diabetes Care Inc Deteccion de analitos por medio de interruptores de proteinas.
JP7720098B2 (ja) 2019-11-26 2025-08-07 コデクシス， インコーポレイテッド 化合物のヒドロキシル化のための生体触媒および方法
CA3165484A1 (en) 2019-12-20 2021-06-24 Codexis, Inc. Engineered acid alpha-glucosidase variants
WO2021158686A1 (en) 2020-02-04 2021-08-12 Codexis, Inc. Engineered leucine decarboxylases
CA3179751A1 (en) 2020-04-10 2021-10-14 Codexis, Inc. Engineered transaminase polypeptides
CA3191900A1 (en) 2020-08-28 2022-03-03 Codexis, Inc. Engineered amylase variants
CA3191867A1 (en) 2020-08-28 2022-03-03 Codexis, Inc. Engineered protease variants
WO2022125960A1 (en) 2020-12-11 2022-06-16 Willow Biosciences, Inc. Recombinant acyl activating enzyme (aae) genes for enhanced biosynthesis of cannabinoids and cannabinoid precursors
US11898174B2 (en) 2020-12-18 2024-02-13 Codexis, Inc. Engineered uridine phosphorylase variant enzymes
WO2022212824A1 (en) 2021-04-02 2022-10-06 Codexis, Inc. Engineered adenylate kinase variant enzymes
WO2022212832A1 (en) 2021-04-02 2022-10-06 Codexis, Inc. Engineered cyclic gmp-amp synthase (cgas) variant enzymes
IL305922A (en) 2021-04-02 2023-11-01 Codexis Inc Transgenic enzymes of variant guanylate kinase
CA3215105A1 (en) 2021-04-02 2022-10-06 Codexis, Inc. Engineered acetate kinase variant enzymes
TW202313969A (zh) 2021-05-21 2023-04-01 美商克迪科思股份有限公司 經工程化的甲硫胺酸γ解離酶變異體
EP4377451A2 (en) 2021-07-30 2024-06-05 Willow Biosciences, Inc. Recombinant prenyltransferase polypeptides engineered for enhanced biosynthesis of cannabinoids
CA3227236A1 (en) 2021-08-19 2023-02-23 Trish Choudhary Recombinant olivetolic acid cyclase polypeptides engineered for enhanced biosynthesis of cannabinoids
WO2023064938A1 (en) 2021-10-15 2023-04-20 Codexis, Inc. Engineered dna polymerase variants
WO2023069921A1 (en) 2021-10-19 2023-04-27 Epimeron Usa, Inc. Recombinant thca synthase polypeptides engineered for enhanced biosynthesis of cannabinoids
JP2025510621A (ja) 2022-03-31 2025-04-15 青島清原化合物有限公司 モノアミン酸化酵素及びその応用
WO2024040020A1 (en) 2022-08-15 2024-02-22 Absci Corporation Quantitative affinity activity specific cell enrichment
EP4649143A1 (en) 2023-01-12 2025-11-19 Novartis AG Engineered ketoreductase polypeptides
WO2025061911A1 (en) 2023-09-22 2025-03-27 Glaxosmithkline Intellectual Property Development Limited Methods of producing nucleotide triphosphates (ntps)
WO2025144700A1 (en) 2023-12-27 2025-07-03 Absci Corporation Nanobody library screening using bacterial surface display
WO2025235589A1 (en) 2024-05-08 2025-11-13 Codexis, Inc. Dna polymerase variants
WO2025242702A1 (en) 2024-05-23 2025-11-27 Glaxosmithkline Intellectual Property Development Limited Enzymatic process for producing n-acetyl galactosamine clusters

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886288A (en) * 1970-06-15 1975-05-27 Swift & Co Cheese manufacture using highly active proteolytic enzymes
JPS5279086A (en) 1975-12-25 1977-07-02 Nippon Soda Co Ltd Preparation of antibiotic tunicamycin
JPS5279083A (en) * 1975-12-26 1977-07-02 Morinaga Milk Industry Co Ltd Production of protein decomposed substance not having bitterness and antigen property
JPS6041751B2 (ja) 1976-06-22 1985-09-18 ジエコ−株式会社 デジタル電子時計
JPS548785A (en) 1977-06-21 1979-01-23 Kikkoman Corp Preparation of protein hydrolyzate
US4839281A (en) † 1985-04-17 1989-06-13 New England Medical Center Hospitals, Inc. Lactobacillus strains and methods of selection
DK589785A (da) 1985-12-18 1987-06-19 Samuelsson Ernst Gunnar Peptidpraeparat, fremgangsmaade til fremstilling deraf samt anvendelse af peptidpraeparatet
EP0322589B1 (fr) † 1987-12-23 1993-01-20 Societe Des Produits Nestle S.A. Procédé de préparation d'un hydrolysat de protéines de lactosérum et d'un aliment hypoallergéniques
DD281540A5 (de) * 1988-08-08 1990-08-15 Berlin Chemie Veb Verfahren zur herstellung von nutritiva
ES2063882T5 (es) † 1989-10-02 2001-12-01 Novartis Nutrition Ag Hidrolizados de proteinas.
JP3071877B2 (ja) † 1991-06-27 2000-07-31 財団法人糧食研究会 経口寛容誘導能を有する低アレルゲン性酵素分解ペプチド組成物
US5952034A (en) * 1991-10-12 1999-09-14 The Regents Of The University Of California Increasing the digestibility of food proteins by thioredoxin reduction
ATE161181T1 (de) * 1992-07-06 1998-01-15 Nestle Sa Lactobacillus acidophilus enthaltende antigastritis-mittel
FI94089C (fi) 1992-12-10 1995-07-25 Valio Oy Menetelmä allergiaa aiheuttavien yhdisteiden poistamiseksi proteiinipitoisista koostumuksista
RU2031586C1 (ru) 1993-02-05 1995-03-27 Тамара Георгиевна Извекова Биологически активный кисломолочный продукт "ацидолакт-наринэ" и способ его получения
GB9312369D0 (en) * 1993-06-16 1993-07-28 Sandoz Nutrition Ltd Organic compounds
AU1076595A (en) † 1993-11-23 1995-06-13 Kabushiki Kaisha Wado Doctors Group Intestinal flora improver composition, and apparatus and system for producing the same
FI104465B (fi) * 1995-06-14 2000-02-15 Valio Oy Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012126481A1 (en) 2011-02-25 2012-09-27 OÜ Tervisliku Piima Biotehnoloogiate Arenduskeskus Isolated microorganism strains lactobacillus plantarum mcc1 dsm 23881 and lactobacillus gasseri mcc2 dsm 23882 and their use

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