DE68917323D1 - Expressions-Vektor für Fusions-Proteine und Immunogen-Proteine. - Google Patents

Expressions-Vektor für Fusions-Proteine und Immunogen-Proteine.

Info

Publication number
DE68917323D1
DE68917323D1 DE68917323T DE68917323T DE68917323D1 DE 68917323 D1 DE68917323 D1 DE 68917323D1 DE 68917323 T DE68917323 T DE 68917323T DE 68917323 T DE68917323 T DE 68917323T DE 68917323 D1 DE68917323 D1 DE 68917323D1
Authority
DE
Germany
Prior art keywords
proteins
expression vector
immunogen
fusion proteins
fusion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68917323T
Other languages
English (en)
Inventor
Jon H Condra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE68917323D1 publication Critical patent/DE68917323D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245—Escherichia (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/455—Eimeria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE68917323T 1988-01-15 1989-01-13 Expressions-Vektor für Fusions-Proteine und Immunogen-Proteine. Expired - Lifetime DE68917323D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/145,800 US4973551A (en) 1988-01-15 1988-01-15 Vector for the expression of fusion proteins and protein immunogens

Publications (1)

Publication Number Publication Date
DE68917323D1 true DE68917323D1 (de) 1994-09-15

Family

ID=22514609

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68917323T Expired - Lifetime DE68917323D1 (de) 1988-01-15 1989-01-13 Expressions-Vektor für Fusions-Proteine und Immunogen-Proteine.

Country Status (5)

Country Link
US (1) US4973551A (de)
EP (1) EP0324647B1 (de)
JP (1) JP2701910B2 (de)
CA (1) CA1310921C (de)
DE (1) DE68917323D1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA894726B (en) * 1988-06-27 1990-03-28 Akzo Nv Coccidiosis vaccine
DE68909041T2 (de) * 1989-06-21 1994-01-13 Akzo Nv Eimeria tenella-Vakzin.
US5098603A (en) * 1990-01-16 1992-03-24 Eastman Kodak Company Stabilized phenol solution
US5474900A (en) * 1990-03-16 1995-12-12 Sekisui Chemical Co., Ltd. Process for preparing purified syphilis antigen from Treponema palljdum
ATE158816T1 (de) 1990-11-26 1997-10-15 Genetics Inst Expression von pace in wirtszellen und verfahren zu dessen verwendung
JP2513703Y2 (ja) * 1991-04-12 1996-10-09 株式会社ゴール ハンドル錠
US5403581A (en) * 1991-07-12 1995-04-04 Hoffmann-La Roche Inc. Coccidiosis vaccines
US6008342A (en) * 1991-07-12 1999-12-28 Roche Vitamins Inc. DNA encoding eimeria antigen
GB9513371D0 (en) 1995-06-30 1995-09-06 Biocine Spa Immunogenic detoxified mutant toxins
US5629167A (en) 1994-04-19 1997-05-13 Biocine S.P.A. Detection of antibodies against Chlamydia trachomatis pgp3 antigen in patient sera by enzyme-linked immunosorbent assay
US5976580A (en) * 1995-06-07 1999-11-02 Novus International, Inc. Nutrient formulation and process for enhancing the health, livability, cumulative weight gain or feed efficiency in poultry and other animals
JP3092904B2 (ja) * 1995-10-13 2000-09-25 株式会社エイチ・エス・ピー研究所 細菌により可溶性蛋白質を生産する方法
US7655436B1 (en) 1996-04-30 2010-02-02 Schering Corporation Expression of soluble heterologous proteins in bacteria utilizing a thioredoxin/protein expression vector
WO1997041207A2 (en) * 1996-04-30 1997-11-06 Schering Corporation Expression of soluble heterologous proteins in bacteria utilizing a thioredoxin/protein expression vector
AU9363798A (en) 1997-11-06 1999-05-31 Chiron S.P.A. Neisserial antigens
CA2317815A1 (en) 1998-01-14 1999-07-22 Chiron S.P.A. Neisseria meningitidis antigens
GB9808932D0 (en) 1998-04-27 1998-06-24 Chiron Spa Polyepitope carrier protein
ES2304065T3 (es) 1998-05-01 2008-09-01 Novartis Vaccines And Diagnostics, Inc. Antigenos y composiciones de neisseria meningitidis.
NZ581940A (en) 1999-04-30 2011-07-29 Novartis Vaccines & Diagnostic Conserved neisserial antigens
GB9911683D0 (en) 1999-05-19 1999-07-21 Chiron Spa Antigenic peptides
GB9916529D0 (en) 1999-07-14 1999-09-15 Chiron Spa Antigenic peptides
RU2281956C2 (ru) 1999-10-29 2006-08-20 Чирон С.Р.Л. Антигенные пептиды neisseria
DK2289545T3 (en) 2000-01-17 2016-09-05 Glaxosmithkline Biologicals Sa Supplemented OMV vaccine against meningococcus
NZ523831A (en) * 2000-07-13 2005-10-28 Invitrogen Corp Methods and compositions for rapid protein and peptide extraction and isolation using a lysis matrix
EP2189473A3 (de) 2000-10-27 2010-08-11 Novartis Vaccines and Diagnostics S.r.l. Nukleinsäure und Proteine von Gruppen A und B Streptokokken
GB0107661D0 (en) 2001-03-27 2001-05-16 Chiron Spa Staphylococcus aureus
GB0107658D0 (en) 2001-03-27 2001-05-16 Chiron Spa Streptococcus pneumoniae
JP4413617B2 (ja) 2001-12-12 2010-02-10 カイロン ソチエタ ア レスポンサビリタ リミタータ Ｃｈｌａｍｙｄｉａｔｒａｃｈｏｍａｔｉｓに対する免疫化
DK2279746T3 (da) 2002-11-15 2013-11-25 Novartis Vaccines & Diagnostic Overfladeproteiner i neisseria meningitidis
GB0308198D0 (en) 2003-04-09 2003-05-14 Chiron Srl ADP-ribosylating bacterial toxin
PT2054431E (pt) 2006-06-09 2011-11-03 Novartis Ag Confórmeros de adesinas bacterianas
US9868946B2 (en) 2012-11-05 2018-01-16 Icahn School Of Medicine At Mount Sinai Method of isolating pure mitochondrial DNA
CN115161306B (zh) * 2022-06-29 2023-09-15 江苏省农业科学院 绿盲蝽rna降解酶、其编码基因、载体、菌株及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4710377A (en) * 1983-08-19 1987-12-01 American Cyanamid Company Antigens and monoclonal antibodies reactive against sporozoites of Eimeria spp.
US4650676A (en) * 1983-08-19 1987-03-17 American Cyanamid Company Antigens and monoclonal antibodies reactive against merozoites of Eimeria spp.
CA1340520C (en) * 1984-06-05 1999-05-04 Karel Z. Newman Jr. Antigenic proteins and vaccines containing them and protective antibodies directed to them for prevention of coccidiosis caused by eimeria tenella and eimeria necatrix
US4639372A (en) * 1984-06-29 1987-01-27 Merck & Co., Inc. Coccidiosis vaccine
EP0190254A4 (de) * 1984-07-05 1987-03-09 Genex Corp Kloniertes gen, verfahren zu dessen herstellung und seine verwendung.
EP0241139A3 (de) * 1986-03-13 1989-04-19 Merck & Co. Inc. Antiidiotypischer Coccidiaimpfstoff

Also Published As

Publication number Publication date
EP0324647A3 (en) 1990-02-28
US4973551A (en) 1990-11-27
JPH025870A (ja) 1990-01-10
EP0324647B1 (de) 1994-08-10
JP2701910B2 (ja) 1998-01-21
CA1310921C (en) 1992-12-01
EP0324647A2 (de) 1989-07-19

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Legal Events

Date Code Title Description
8332 No legal effect for de