DK395288D0 - Proteiner - Google Patents

Proteiner

Info

Publication number
DK395288D0
DK395288D0 DK395288A DK395288A DK395288D0 DK 395288 D0 DK395288 D0 DK 395288D0 DK 395288 A DK395288 A DK 395288A DK 395288 A DK395288 A DK 395288A DK 395288 D0 DK395288 D0 DK 395288D0
Authority
DK
Denmark
Prior art keywords
proteins
Prior art date
Application number
DK395288A
Other languages
English (en)
Inventor
Lars Christian Petersen
Esper Boel
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri As filed Critical Novo Industri As
Priority to DK395288A priority Critical patent/DK395288D0/da
Publication of DK395288D0 publication Critical patent/DK395288D0/da
Priority to AU39769/89A priority patent/AU630879B2/en
Priority to JP1507718A priority patent/JPH03505967A/ja
Priority to FI910183A priority patent/FI910183A7/fi
Priority to PCT/DK1989/000171 priority patent/WO1990000600A1/en
Priority to CN89104871A priority patent/CN1039440A/zh
Priority to EP19890307194 priority patent/EP0351246A3/en
Priority to NO91910149A priority patent/NO910149L/no
Priority to DK007491A priority patent/DK7491A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK395288A 1988-07-15 1988-07-15 Proteiner DK395288D0 (da)

Priority Applications (9)

Application Number Priority Date Filing Date Title
DK395288A DK395288D0 (da) 1988-07-15 1988-07-15 Proteiner
AU39769/89A AU630879B2 (en) 1988-07-15 1989-07-07 A tissue plasminogen activator analogue
JP1507718A JPH03505967A (ja) 1988-07-15 1989-07-07 組織プラスミノーゲン活性化因子類似体
FI910183A FI910183A7 (fi) 1988-07-15 1989-07-07 Plasminogeenin kudosaktivaattorin analogi
PCT/DK1989/000171 WO1990000600A1 (en) 1988-07-15 1989-07-07 A tissue plasminogen activator analogue
CN89104871A CN1039440A (zh) 1988-07-15 1989-07-14 组织血纤维蛋白溶酶原激活剂类似物的制备方法
EP19890307194 EP0351246A3 (en) 1988-07-15 1989-07-14 A tissue plasminogen activator analogue
NO91910149A NO910149L (no) 1988-07-15 1991-01-14 Vevs-plasminogen-aktivator-analog.
DK007491A DK7491A (da) 1988-07-15 1991-01-15 Vaevsplasminogenaktivatoranalog

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK395288A DK395288D0 (da) 1988-07-15 1988-07-15 Proteiner

Publications (1)

Publication Number Publication Date
DK395288D0 true DK395288D0 (da) 1988-07-15

Family

ID=8128619

Family Applications (1)

Application Number Title Priority Date Filing Date
DK395288A DK395288D0 (da) 1988-07-15 1988-07-15 Proteiner

Country Status (6)

Country Link
EP (1) EP0351246A3 (da)
JP (1) JPH03505967A (da)
CN (1) CN1039440A (da)
AU (1) AU630879B2 (da)
DK (1) DK395288D0 (da)
WO (1) WO1990000600A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5156969A (en) * 1988-09-02 1992-10-20 Genentech Inc. Tissue plasminogen activator variant with deletion of amino acids 466-470 having fibrin specific properties
US5108901A (en) * 1988-09-02 1992-04-28 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties
US5262170A (en) * 1988-09-02 1993-11-16 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties and substituted at amino acid positions 296-299, DNA molecules encoding them, vectors, and host cells
US5714145A (en) * 1988-09-02 1998-02-03 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties
CA2007364A1 (en) * 1989-01-17 1990-07-17 David J. Livingston Gene sequences encoding modified residues situated in the protease domain of tpa
PT786257E (pt) * 1992-06-03 2003-12-31 Genentech Inc Variantes de glicosilacao do activador de plasminogenio tissular com propriedades terapeuticas meloradas
US6706504B1 (en) 1996-11-12 2004-03-16 The Scripps Research Institute Tissue type plasminogen activator (t-PA) variants: compositions and methods of use
WO1999009184A1 (de) * 1997-08-13 1999-02-25 Roche Diagnostics Gmbh Plasminogenaktivator mit verbesserter zymogenität und verminderter fibrinbindung
CN107760660B (zh) * 2017-12-13 2020-10-02 福州大学 一种组织型纤溶酶原激活剂突变体及其应用
CN110628751B (zh) * 2019-10-31 2021-04-27 福州大学 一种瑞替普酶的突变体设计及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK345087A (da) * 1986-07-11 1988-01-12 Novo Industri As Modificeret vaevsplasminogenaktivator
US5108901A (en) * 1988-09-02 1992-04-28 Genentech, Inc. Tissue plasminogen activator having zymogenic or fibrin specific properties

Also Published As

Publication number Publication date
WO1990000600A1 (en) 1990-01-25
AU3976989A (en) 1990-02-05
EP0351246A3 (en) 1990-09-12
AU630879B2 (en) 1992-11-12
CN1039440A (zh) 1990-02-07
EP0351246A2 (en) 1990-01-17
JPH03505967A (ja) 1991-12-26

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment