ATA901789A - Somatostatinpeptid - Google Patents

Somatostatinpeptid

Info

Publication number
ATA901789A
ATA901789A AT0901789A AT901789A ATA901789A AT A901789 A ATA901789 A AT A901789A AT 0901789 A AT0901789 A AT 0901789A AT 901789 A AT901789 A AT 901789A AT A901789 A ATA901789 A AT A901789A
Authority
AT
Austria
Prior art keywords
somatostatinpeptid
Prior art date
Application number
AT0901789A
Other languages
English (en)
Other versions
AT403476B (de
Inventor
Rainer Albert
Eric P Krenning
Steven W J Lamberts
Janos Pless
Original Assignee
Novartis Erfind Verwalt Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888828364A external-priority patent/GB8828364D0/en
Priority claimed from GB898916115A external-priority patent/GB8916115D0/en
Priority claimed from GB898916761A external-priority patent/GB8916761D0/en
Application filed by Novartis Erfind Verwalt Gmbh filed Critical Novartis Erfind Verwalt Gmbh
Publication of ATA901789A publication Critical patent/ATA901789A/de
Application granted granted Critical
Publication of AT403476B publication Critical patent/AT403476B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT0901789A 1988-12-05 1989-11-30 Somatostatinpeptid AT403476B (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB888828364A GB8828364D0 (en) 1988-12-05 1988-12-05 Improvements in/relating to organic compounds
GB898916115A GB8916115D0 (en) 1989-07-13 1989-07-13 Improvements in or relating to organic compounds
GB898916761A GB8916761D0 (en) 1989-07-21 1989-07-21 Improvements in or relating to organic compounds

Publications (2)

Publication Number Publication Date
ATA901789A true ATA901789A (de) 1997-07-15
AT403476B AT403476B (de) 1998-02-25

Family

ID=27264222

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0901789A AT403476B (de) 1988-12-05 1989-11-30 Somatostatinpeptid

Country Status (24)

Country Link
JP (2) JP2726320B2 (de)
KR (1) KR0156541B1 (de)
AT (1) AT403476B (de)
AU (1) AU633859B2 (de)
BE (1) BE1002296A5 (de)
CA (1) CA2004532C (de)
CH (1) CH678329A5 (de)
DE (1) DE3991505B4 (de)
DK (1) DK175338B1 (de)
ES (1) ES2023533A6 (de)
FI (1) FI102540B1 (de)
FR (1) FR2639947B1 (de)
GB (1) GB2225579B (de)
HK (1) HK189995A (de)
HU (2) HUT53375A (de)
IE (1) IE62091B1 (de)
IL (1) IL92534A (de)
LU (1) LU87633A1 (de)
MY (1) MY106120A (de)
NL (1) NL194828C (de)
PT (1) PT92487B (de)
SA (1) SA96160495B1 (de)
SE (1) SE508799C2 (de)
WO (1) WO1990006949A2 (de)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU639371B2 (en) * 1987-07-10 1993-07-22 Novartis Ag Method of treating breast cancer
DE3822557C2 (de) * 1987-07-10 1998-07-02 Ciba Geigy Ag Arzneimittel, enthaltend Somatostatine
GB9111199D0 (en) * 1991-05-23 1991-07-17 Sandoz Ltd Improvements in or relating to organic compounds
US5460785A (en) * 1989-08-09 1995-10-24 Rhomed Incorporated Direct labeling of antibodies and other protein with metal ions
US5700444A (en) * 1992-02-20 1997-12-23 Rhomed Incorporated Chemotactic peptide pharmaceutical applications
US5985240A (en) * 1989-08-09 1999-11-16 Rhomed Incorporated Peptide radiopharmaceutical applications
US5443816A (en) * 1990-08-08 1995-08-22 Rhomed Incorporated Peptide-metal ion pharmaceutical preparation and method
GB9004017D0 (en) * 1990-02-22 1990-04-18 Krenning Eric P Improvements in or relating to organic compounds
US5382654A (en) * 1992-02-05 1995-01-17 Mallinckrodt Medical, Inc. Radiolabelled peptide compounds
US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
US7238340B1 (en) 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
US5443815A (en) * 1991-11-27 1995-08-22 Diatech, Inc. Technetium-99m labeled peptides for imaging
IE920416A1 (en) * 1991-02-08 1992-08-12 Biomeasure Method of treating benign and malignant proliferative skin¹disease
AU657770B2 (en) * 1991-06-03 1995-03-23 Mallinckrodt Medical, Inc. Radiolabelled somatostatin derivatives, their preparation and use
WO1993004702A1 (en) * 1991-08-29 1993-03-18 Mallinckrodt Medical, Inc. Use of gentisic acid or gentisyl alcohol for stabilising radiolabeled peptides and proteins
US5225180A (en) * 1991-09-10 1993-07-06 Diatech, Inc. Technetium-99m labeled somatostatin-derived peptides for imaging
US5783170A (en) * 1991-11-27 1998-07-21 Diatide, Inc. Peptide-metal chelate conjugates
AU683833B2 (en) * 1992-01-03 1997-11-27 Rhomed Incorporated Protein- and peptide-metal ion pharmaceutical applications
US5738838A (en) * 1992-02-20 1998-04-14 Rhomed Incorporated IKVAV peptide radiopharmaceutical applications
US5556609A (en) * 1992-02-20 1996-09-17 Rhomed Incorporated YIGSR peptide radiopharmaceutical applications
EP0642357B1 (de) * 1992-02-05 2001-07-25 Mallinckrodt Inc. Radioaktiv markierte somatostatin
US5371184A (en) * 1992-02-05 1994-12-06 Mallinckrodt Medical, Inc. Radiolabelled peptide compounds
US5643549A (en) * 1992-02-20 1997-07-01 Rhomed Incorporated Leukostimulatory agent for in vivo leukocyte tagging
EP0636032A1 (de) * 1992-03-25 1995-02-01 Mallinckrodt Medical, Inc. Methode zur Feststellung und Lokalisierung von Tumorgeweben während einerOperation
US6017512A (en) * 1992-06-23 2000-01-25 Diatide, Inc. Radiolabeled peptides
US5871711A (en) * 1992-06-23 1999-02-16 Diatide, Inc. Radioactively-labeled somatostatin-derived peptides for imaging and therapeutic uses
US5620675A (en) * 1992-06-23 1997-04-15 Diatech, Inc. Radioactive peptides
US5716596A (en) * 1992-06-23 1998-02-10 Diatide, Inc. Radioactively labeled somatostatin-derived peptides for imaging and therapeutic uses
US5650134A (en) * 1993-01-12 1997-07-22 Novartis Ag (Formerly Sandoz Ltd.) Peptides
FI940109A7 (fi) * 1993-01-12 1994-10-11 Novartis Ag Peptidejä
CA2154667A1 (en) * 1993-02-02 1994-08-18 Linda M. Gustavson Directed biodistribution of small molecules
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
US5932189A (en) * 1994-07-29 1999-08-03 Diatech, Inc. Cyclic peptide somatostatin analogs
EP0720621B1 (de) * 1993-06-23 2001-02-07 Diatide, Inc. Radiomarkierte somatostatin derivate zur abbildung und zur therapeutischen verwendung
CA2190727C (en) * 1994-05-19 2006-07-18 Sudhakar Kasina Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging
US6051206A (en) * 1994-06-03 2000-04-18 Diatide, Inc Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
GB9417873D0 (en) * 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
US5632969A (en) * 1994-10-13 1997-05-27 Merck & Co., Inc. N3 S2 chelating ligands optionally radiolabelled with Tc or Re, useful for diagnostic or therapeutic applications
US5556939A (en) * 1994-10-13 1996-09-17 Merck Frosst Canada, Inc. TC or RE radionuclide labelled chelate, hexapeptide complexes useful for diagnostic or therapeutic applications
US5830431A (en) * 1995-06-07 1998-11-03 Mallinckrodt Medical, Inc. Radiolabeled peptide compositions for site-specific targeting
GB9708265D0 (en) 1997-04-24 1997-06-18 Nycomed Imaging As Contrast agents
FI965181L (fi) * 1996-12-20 1998-06-21 Map Medical Technologies Oy Polyalkoholi-peptidijohdannaiset
US6630570B1 (en) 1999-04-09 2003-10-07 Insitut für Diagnostikforschung GmbH Short-chain peptide-dye conjugates as contrast media for optical diagnosis
DE19917713A1 (de) * 1999-04-09 2000-10-19 Diagnostikforschung Inst Kurzkettige Peptid-Farbstoffkonjugate als Konstrastmittel für die optische Diagnostik
US7175953B2 (en) 1999-04-09 2007-02-13 Institute Fuer Diagnostik Forschung Short-warp peptide-dye conjugate as contrast agent for optical diagnostic
US6685914B1 (en) 1999-09-13 2004-02-03 Bristol-Myers Squibb Pharma Company Macrocyclic chelants for metallopharmaceuticals
ATE427125T1 (de) 2001-04-23 2009-04-15 Mallinckrodt Inc Tc und re markierte radioaktive glycosylierte octreotid-derivate
US7968080B2 (en) 2003-08-20 2011-06-28 The Regents Of The University Of California Somatostatin analogs with inhibitory activity to growth hormone release
US7611693B2 (en) * 2003-09-17 2009-11-03 Board Of Regents, The Univerisity Of Texas System Mechanism-based targeted pancreatic beta cell imaging and therapy
EP2067786A1 (de) 2007-12-07 2009-06-10 ITALFARMACO S.p.A. Neue nichtselektive Analoga von Somatostatin
EP2922578B1 (de) 2012-11-21 2018-12-12 Serene, Llc Tin-117m-somatostatinrezeptor-bindende verbindungen
CN119708199A (zh) 2023-09-27 2025-03-28 钱杭江医药科技(嘉兴)有限公司 生长抑素肽类类似物、螯合物及其应用

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1222691A (en) * 1981-12-29 1987-06-09 Wilhelmus T. Goedemans Method of preparing radionuclide-labelled proteins, in particular antibodies or antibody fragments
US4652519A (en) * 1983-02-03 1987-03-24 Yeda Research And Development Company Limited Bifunctional chelating agents and process for their production
US4707352A (en) * 1984-01-30 1987-11-17 Enzo Biochem, Inc. Method of radioactively labeling diagnostic and therapeutic agents containing a chelating group
DE3511206A1 (de) * 1985-03-28 1986-10-09 Sandoz-Patent-GmbH, 7850 Lörrach Neue polypeptidderivate, ihre herstellung und pharmazeutische praeparate, welche diese polypeptidderivate enthalten
HUT42101A (en) * 1985-01-07 1987-06-29 Sandoz Ag Process for preparing stomatostatine derivatives and pharmaceutical compositions containing such compounds
DE3522638A1 (de) * 1985-06-25 1987-01-08 Diamalt Ag Neue somatostatin-derivate
US4678667A (en) * 1985-07-02 1987-07-07 501 Regents of the University of California Macrocyclic bifunctional chelating agents
CA1266344A (en) * 1986-02-14 1990-02-27 Miki Kurami High molecular compounds having amino groups, and their utilization
US4732974A (en) * 1986-03-05 1988-03-22 Mallinckrodt, Inc. Metal ion labeling of carrier molecules
US4861869A (en) * 1986-05-29 1989-08-29 Mallinckrodt, Inc. Coupling agents for joining radionuclide metal ions with biologically useful proteins
HU906340D0 (en) * 1986-10-13 1991-04-29 Sandoz Ag Synthesis in solid phase for producing peptonic alcohols
CH679045A5 (de) * 1987-06-29 1991-12-13 Sandoz Ag
US5073541A (en) * 1987-11-18 1991-12-17 Administrators Of The Tulane Educational Fund Treatment of small cell lung cancer with somatostatin analogs
FR2638968B1 (fr) * 1988-11-11 1994-10-07 Sandoz Sa Nouvelle utilisation therapeutique de la somatostatine et de ses analogues et derives

Also Published As

Publication number Publication date
NL194828B (nl) 2002-12-02
GB2225579B (en) 1993-03-17
FR2639947A1 (fr) 1990-06-08
IE62091B1 (en) 1994-12-14
CH678329A5 (de) 1991-08-30
FI102540B (fi) 1998-12-31
AU633859B2 (en) 1993-02-11
KR0156541B1 (ko) 1998-10-15
SA96160495B1 (ar) 2006-08-23
WO1990006949A3 (en) 1990-07-26
CA2004532C (en) 2000-02-22
JPH1095737A (ja) 1998-04-14
PT92487B (pt) 1996-01-31
AU4587189A (en) 1990-06-14
DK612689A (da) 1990-06-06
HU896359D0 (en) 1990-02-28
JP2726320B2 (ja) 1998-03-11
HU211468A9 (en) 1995-11-28
FI895809A0 (fi) 1989-12-04
DE3991505B4 (de) 2006-04-20
GB8927255D0 (en) 1990-01-31
AT403476B (de) 1998-02-25
JPH02184698A (ja) 1990-07-19
SE8904087D0 (sv) 1989-12-04
JP3686503B2 (ja) 2005-08-24
FI102540B1 (fi) 1998-12-31
NL194828C (nl) 2003-04-03
HK189995A (en) 1995-12-29
GB2225579A (en) 1990-06-06
FR2639947B1 (fr) 1995-04-21
KR900009697A (ko) 1990-07-05
ES2023533A6 (es) 1992-01-16
WO1990006949A2 (en) 1990-06-28
HUT53375A (en) 1990-10-28
IE893866L (en) 1990-06-05
PT92487A (pt) 1990-06-29
IL92534A (en) 1994-06-24
CA2004532A1 (en) 1990-06-05
DK175338B1 (da) 2004-08-30
MY106120A (en) 1995-03-31
BE1002296A5 (fr) 1990-11-20
SE508799C2 (sv) 1998-11-09
SE8904087L (sv) 1991-06-05
NL8902981A (nl) 1990-07-02
DK612689D0 (da) 1989-12-05
LU87633A1 (fr) 1991-09-18

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