SE8904087D0 - Peptide derivates - Google Patents

Peptide derivates

Info

Publication number
SE8904087D0
SE8904087D0 SE8904087A SE8904087A SE8904087D0 SE 8904087 D0 SE8904087 D0 SE 8904087D0 SE 8904087 A SE8904087 A SE 8904087A SE 8904087 A SE8904087 A SE 8904087A SE 8904087 D0 SE8904087 D0 SE 8904087D0
Authority
SE
Sweden
Prior art keywords
somatostatin
peptide
detectable element
amino group
group
Prior art date
Application number
SE8904087A
Other languages
English (en)
Other versions
SE508799C2 (sv
SE8904087L (sv
Inventor
R Albert
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888828364A external-priority patent/GB8828364D0/en
Priority claimed from GB898916115A external-priority patent/GB8916115D0/en
Priority claimed from GB898916761A external-priority patent/GB8916761D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE8904087D0 publication Critical patent/SE8904087D0/sv
Publication of SE8904087L publication Critical patent/SE8904087L/sv
Publication of SE508799C2 publication Critical patent/SE508799C2/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
SE8904087A 1988-12-05 1989-12-04 Somatostatinpeptid, förfarande för dess framställning och dess användning SE508799C2 (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB888828364A GB8828364D0 (en) 1988-12-05 1988-12-05 Improvements in/relating to organic compounds
GB898916115A GB8916115D0 (en) 1989-07-13 1989-07-13 Improvements in or relating to organic compounds
GB898916761A GB8916761D0 (en) 1989-07-21 1989-07-21 Improvements in or relating to organic compounds

Publications (3)

Publication Number Publication Date
SE8904087D0 true SE8904087D0 (sv) 1989-12-04
SE8904087L SE8904087L (sv) 1991-06-05
SE508799C2 SE508799C2 (sv) 1998-11-09

Family

ID=27264222

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8904087A SE508799C2 (sv) 1988-12-05 1989-12-04 Somatostatinpeptid, förfarande för dess framställning och dess användning

Country Status (24)

Country Link
JP (2) JP2726320B2 (sv)
KR (1) KR0156541B1 (sv)
AT (1) AT403476B (sv)
AU (1) AU633859B2 (sv)
BE (1) BE1002296A5 (sv)
CA (1) CA2004532C (sv)
CH (1) CH678329A5 (sv)
DE (1) DE3991505B4 (sv)
DK (1) DK175338B1 (sv)
ES (1) ES2023533A6 (sv)
FI (1) FI102540B (sv)
FR (1) FR2639947B1 (sv)
GB (1) GB2225579B (sv)
HK (1) HK189995A (sv)
HU (2) HUT53375A (sv)
IE (1) IE62091B1 (sv)
IL (1) IL92534A (sv)
LU (1) LU87633A1 (sv)
MY (1) MY106120A (sv)
NL (1) NL194828C (sv)
PT (1) PT92487B (sv)
SA (1) SA96160495B1 (sv)
SE (1) SE508799C2 (sv)
WO (1) WO1990006949A2 (sv)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3845000C2 (de) * 1987-07-10 1998-11-19 Novartis Ag Anwendung von Octreotid zur Behandlung von Brustkrebs
AU639371B2 (en) * 1987-07-10 1993-07-22 Novartis Ag Method of treating breast cancer
GB9111199D0 (en) * 1991-05-23 1991-07-17 Sandoz Ltd Improvements in or relating to organic compounds
US5443816A (en) * 1990-08-08 1995-08-22 Rhomed Incorporated Peptide-metal ion pharmaceutical preparation and method
US5460785A (en) * 1989-08-09 1995-10-24 Rhomed Incorporated Direct labeling of antibodies and other protein with metal ions
US5985240A (en) * 1989-08-09 1999-11-16 Rhomed Incorporated Peptide radiopharmaceutical applications
US5700444A (en) * 1992-02-20 1997-12-23 Rhomed Incorporated Chemotactic peptide pharmaceutical applications
GB9004017D0 (en) * 1990-02-22 1990-04-18 Krenning Eric P Improvements in or relating to organic compounds
US5382654A (en) * 1992-02-05 1995-01-17 Mallinckrodt Medical, Inc. Radiolabelled peptide compounds
US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
US7238340B1 (en) 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
US5443815A (en) * 1991-11-27 1995-08-22 Diatech, Inc. Technetium-99m labeled peptides for imaging
WO1992013554A1 (en) * 1991-02-08 1992-08-20 Biomeasure, Inc. Method of treating benign and malignant proliferative skin disease
JPH06508357A (ja) * 1991-06-03 1994-09-22 マリンクロッド・メディカル・インコーポレイテッド 標識ポリペプチド、その製造法および使用
EP0600992B1 (en) * 1991-08-29 2000-09-20 Mallinckrodt Medical, Inc. Use of gentisic acid or gentisyl alcohol for stabilising radiolabeled peptides and proteins
US5225180A (en) * 1991-09-10 1993-07-06 Diatech, Inc. Technetium-99m labeled somatostatin-derived peptides for imaging
US5783170A (en) * 1991-11-27 1998-07-21 Diatide, Inc. Peptide-metal chelate conjugates
DK0629133T3 (da) * 1992-01-03 2001-04-02 Rhomed Inc Farmaceutisk anvendelse af peptidmetalioner
US5738838A (en) * 1992-02-20 1998-04-14 Rhomed Incorporated IKVAV peptide radiopharmaceutical applications
US5556609A (en) * 1992-02-20 1996-09-17 Rhomed Incorporated YIGSR peptide radiopharmaceutical applications
US5371184A (en) * 1992-02-05 1994-12-06 Mallinckrodt Medical, Inc. Radiolabelled peptide compounds
EP1099693A1 (en) * 1992-02-05 2001-05-16 Mallinckrodt Inc. Radiolabelled peptide compounds
US5643549A (en) * 1992-02-20 1997-07-01 Rhomed Incorporated Leukostimulatory agent for in vivo leukocyte tagging
JPH07505621A (ja) * 1992-03-25 1995-06-22 マリンクロッド・インコーポレイテッド 外科手術中における腫瘍組織の検出および探知法
US5716596A (en) * 1992-06-23 1998-02-10 Diatide, Inc. Radioactively labeled somatostatin-derived peptides for imaging and therapeutic uses
US5620675A (en) 1992-06-23 1997-04-15 Diatech, Inc. Radioactive peptides
US5871711A (en) * 1992-06-23 1999-02-16 Diatide, Inc. Radioactively-labeled somatostatin-derived peptides for imaging and therapeutic uses
US6017512A (en) * 1992-06-23 2000-01-25 Diatide, Inc. Radiolabeled peptides
IL108308A0 (en) * 1993-01-12 1994-04-12 Sandoz Ag Polypeptides, their production and pharmaceutical compositions containing them
US5650134A (en) * 1993-01-12 1997-07-22 Novartis Ag (Formerly Sandoz Ltd.) Peptides
CA2154667A1 (en) * 1993-02-02 1994-08-18 Linda M. Gustavson Directed biodistribution of small molecules
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
US5932189A (en) * 1994-07-29 1999-08-03 Diatech, Inc. Cyclic peptide somatostatin analogs
DE69434832D1 (de) * 1993-06-23 2006-10-05 Diatide Inc Radioaktiv-markierte Peptidderivate des Somatostatins zur bildformenden und therapeutischen Verwendung
CA2190727C (en) * 1994-05-19 2006-07-18 Sudhakar Kasina Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging
US6051206A (en) * 1994-06-03 2000-04-18 Diatide, Inc Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
GB9417873D0 (en) 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
US5632969A (en) * 1994-10-13 1997-05-27 Merck & Co., Inc. N3 S2 chelating ligands optionally radiolabelled with Tc or Re, useful for diagnostic or therapeutic applications
US5556939A (en) * 1994-10-13 1996-09-17 Merck Frosst Canada, Inc. TC or RE radionuclide labelled chelate, hexapeptide complexes useful for diagnostic or therapeutic applications
US5830431A (en) * 1995-06-07 1998-11-03 Mallinckrodt Medical, Inc. Radiolabeled peptide compositions for site-specific targeting
GB9708265D0 (en) * 1997-04-24 1997-06-18 Nycomed Imaging As Contrast agents
FI965181A (sv) 1996-12-20 1998-06-21 Map Medical Technologies Oy Polyalkohol-peptidderivat
DE19917713A1 (de) * 1999-04-09 2000-10-19 Diagnostikforschung Inst Kurzkettige Peptid-Farbstoffkonjugate als Konstrastmittel für die optische Diagnostik
US7175953B2 (en) 1999-04-09 2007-02-13 Institute Fuer Diagnostik Forschung Short-warp peptide-dye conjugate as contrast agent for optical diagnostic
US6630570B1 (en) 1999-04-09 2003-10-07 Insitut für Diagnostikforschung GmbH Short-chain peptide-dye conjugates as contrast media for optical diagnosis
US6685914B1 (en) 1999-09-13 2004-02-03 Bristol-Myers Squibb Pharma Company Macrocyclic chelants for metallopharmaceuticals
CA2443273C (en) * 2001-04-23 2011-09-27 Mallinckrodt Inc. Tc and re labeled radioactive glycosylated octreotide derivatives
US7968080B2 (en) 2003-08-20 2011-06-28 The Regents Of The University Of California Somatostatin analogs with inhibitory activity to growth hormone release
PT1675625E (pt) * 2003-09-17 2013-05-23 Univ Texas Imagiologia de células beta pancreáticas direccionada com base no mecanismo
EP2067786A1 (en) 2007-12-07 2009-06-10 ITALFARMACO S.p.A. Novel non selective analogs of somatostatin
EP2922578B1 (en) 2012-11-21 2018-12-12 Serene, Llc Tin-117m comprising somatostatin receptor binding compounds

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1222691A (en) * 1981-12-29 1987-06-09 Wilhelmus T. Goedemans Method of preparing radionuclide-labelled proteins, in particular antibodies or antibody fragments
US4652519A (en) * 1983-02-03 1987-03-24 Yeda Research And Development Company Limited Bifunctional chelating agents and process for their production
US4707352A (en) * 1984-01-30 1987-11-17 Enzo Biochem, Inc. Method of radioactively labeling diagnostic and therapeutic agents containing a chelating group
HUT42101A (en) * 1985-01-07 1987-06-29 Sandoz Ag Process for preparing stomatostatine derivatives and pharmaceutical compositions containing such compounds
DE3511206A1 (de) * 1985-03-28 1986-10-09 Sandoz-Patent-GmbH, 7850 Lörrach Neue polypeptidderivate, ihre herstellung und pharmazeutische praeparate, welche diese polypeptidderivate enthalten
DE3522638A1 (de) * 1985-06-25 1987-01-08 Diamalt Ag Neue somatostatin-derivate
US4678667A (en) * 1985-07-02 1987-07-07 501 Regents of the University of California Macrocyclic bifunctional chelating agents
AU593611B2 (en) * 1986-02-14 1990-02-15 Nihon Medi-Physics Co., Ltd. High molecular compounds having amino groups, and their utilization
US4732974A (en) * 1986-03-05 1988-03-22 Mallinckrodt, Inc. Metal ion labeling of carrier molecules
US4861869A (en) * 1986-05-29 1989-08-29 Mallinckrodt, Inc. Coupling agents for joining radionuclide metal ions with biologically useful proteins
HU906340D0 (en) * 1986-10-13 1991-04-29 Sandoz Ag Synthesis in solid phase for producing peptonic alcohols
CH679045A5 (sv) * 1987-06-29 1991-12-13 Sandoz Ag
US5073541A (en) * 1987-11-18 1991-12-17 Administrators Of The Tulane Educational Fund Treatment of small cell lung cancer with somatostatin analogs
BE1003762A3 (fr) * 1988-11-11 1992-06-09 Sandoz Sa Nouvelle utilisation therapeutique de la somatostatine et de ses analogues et derives.

Also Published As

Publication number Publication date
DE3991505B4 (de) 2006-04-20
CH678329A5 (sv) 1991-08-30
GB2225579B (en) 1993-03-17
IL92534A (en) 1994-06-24
FI102540B1 (sv) 1998-12-31
CA2004532A1 (en) 1990-06-05
NL194828C (nl) 2003-04-03
AT403476B (de) 1998-02-25
KR0156541B1 (ko) 1998-10-15
LU87633A1 (fr) 1991-09-18
HU211468A9 (en) 1995-11-28
DK612689D0 (da) 1989-12-05
GB2225579A (en) 1990-06-06
SE508799C2 (sv) 1998-11-09
FR2639947B1 (fr) 1995-04-21
AU4587189A (en) 1990-06-14
SE8904087L (sv) 1991-06-05
ES2023533A6 (es) 1992-01-16
ATA901789A (de) 1997-07-15
KR900009697A (ko) 1990-07-05
IE893866L (en) 1990-06-05
MY106120A (en) 1995-03-31
HUT53375A (en) 1990-10-28
WO1990006949A2 (en) 1990-06-28
DK612689A (da) 1990-06-06
GB8927255D0 (en) 1990-01-31
AU633859B2 (en) 1993-02-11
JPH1095737A (ja) 1998-04-14
HU896359D0 (en) 1990-02-28
FI102540B (sv) 1998-12-31
PT92487A (pt) 1990-06-29
NL8902981A (nl) 1990-07-02
BE1002296A5 (fr) 1990-11-20
IE62091B1 (en) 1994-12-14
PT92487B (pt) 1996-01-31
FI895809A0 (fi) 1989-12-04
JP3686503B2 (ja) 2005-08-24
JPH02184698A (ja) 1990-07-19
HK189995A (en) 1995-12-29
JP2726320B2 (ja) 1998-03-11
SA96160495B1 (ar) 2006-08-23
FR2639947A1 (fr) 1990-06-08
CA2004532C (en) 2000-02-22
DK175338B1 (da) 2004-08-30
NL194828B (nl) 2002-12-02
WO1990006949A3 (en) 1990-07-26

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