DE69825625D1 - Aminobiguanide und ihre verwendung zur desinfektion von kontaktlinsen und konservierung von pharmazeutischen zubereitungen - Google Patents

Aminobiguanide und ihre verwendung zur desinfektion von kontaktlinsen und konservierung von pharmazeutischen zubereitungen

Info

Publication number
DE69825625D1
DE69825625D1 DE69825625T DE69825625T DE69825625D1 DE 69825625 D1 DE69825625 D1 DE 69825625D1 DE 69825625 T DE69825625 T DE 69825625T DE 69825625 T DE69825625 T DE 69825625T DE 69825625 D1 DE69825625 D1 DE 69825625D1
Authority
DE
Germany
Prior art keywords
aminobiguanides
preservating
contact lenses
pharmaceutical preparations
disinfecting contact
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69825625T
Other languages
English (en)
Other versions
DE69825625T2 (de
Inventor
Joonsup Park
L Dassanayake
D Mcqueen
L Schlitzer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Alcon Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Laboratories Inc filed Critical Alcon Laboratories Inc
Publication of DE69825625D1 publication Critical patent/DE69825625D1/de
Application granted granted Critical
Publication of DE69825625T2 publication Critical patent/DE69825625T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A61L12/141—Biguanides, e.g. chlorhexidine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44—Guanidine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Eyeglasses (AREA)
DE69825625T 1997-12-19 1998-12-18 Aminobiguanide und ihre verwendung zur desinfektion von kontaktlinsen und konservierung von pharmazeutischen zubereitungen Expired - Fee Related DE69825625T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6833097P 1997-12-19 1997-12-19
US68330P 1997-12-19
PCT/US1998/027332 WO1999032158A2 (en) 1997-12-19 1998-12-18 Aminobiguanides to disinfect contact lenses and preserve pharmaceutical compositions

Publications (2)

Publication Number Publication Date
DE69825625D1 true DE69825625D1 (de) 2004-09-16
DE69825625T2 DE69825625T2 (de) 2005-09-15

Family

ID=22081876

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69825625T Expired - Fee Related DE69825625T2 (de) 1997-12-19 1998-12-18 Aminobiguanide und ihre verwendung zur desinfektion von kontaktlinsen und konservierung von pharmazeutischen zubereitungen

Country Status (17)

Country Link
US (2) US6664294B1 (de)
EP (1) EP1042007B1 (de)
JP (1) JP4027595B2 (de)
KR (1) KR100489905B1 (de)
AR (1) AR016708A1 (de)
AT (1) ATE273031T1 (de)
AU (1) AU751002B2 (de)
BR (1) BR9814299A (de)
CA (1) CA2309172C (de)
DE (1) DE69825625T2 (de)
ES (1) ES2226198T3 (de)
HK (1) HK1029290A1 (de)
NO (1) NO20003119L (de)
NZ (1) NZ505742A (de)
TW (1) TW516960B (de)
WO (1) WO1999032158A2 (de)
ZA (1) ZA9811445B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA9811445B (en) 1997-12-19 1999-08-16 Alcon Lab Inc Aminobiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions.
EP1250133B1 (de) * 2000-01-25 2005-03-30 Alcon Inc. Antiallergische ophthalmische zubereitungen, geeignet zur anwendung mit kontaktlinsen
PL211494B1 (pl) 2001-12-21 2012-05-31 Alcon Zastosowanie syntetycznych, nieorganicznych nanocząstek jako nośników dla leków i kompozycja farmaceutyczna do oczu lub uszu
WO2003059193A2 (en) 2001-12-21 2003-07-24 Alcon, Inc. Use of nanoparticles as carriers for biocides in ophthalmic compositions
TWI322828B (en) * 2002-12-23 2010-04-01 Alcon Inc Use of multifunctional surface active agents to clean contact lenses
TWI354021B (en) 2002-12-23 2011-12-11 Alcon Inc Compositions and methods for inhibiting protein on
US20050118129A1 (en) * 2003-12-01 2005-06-02 Erning Xia Gentle and enhanced preservative systems
US6936640B2 (en) * 2003-12-04 2005-08-30 Alcon, Inc. Biguanide/quaternary ammonium containing copolymeric biocides and use thereof in pharmaceutical compositions
CA2545962A1 (en) * 2003-12-09 2005-07-07 Alcon, Inc. Use of organic buffering agents to enhance the antimicrobial activity of pharmaceutical compositions
EP2062872B1 (de) * 2003-12-09 2015-12-09 Novartis AG Verwendung von Bisaminen zur Verstärkung der antimikrobiellen Wirkung von wässrigen Zusammensetzungen
JP5033380B2 (ja) * 2006-08-30 2012-09-26 ディバーシー株式会社 食器、調理器具、食品加工場内もしくは厨房内の設備用殺菌剤組成物および殺菌洗浄剤組成物、ならびにこれらを用いた食器、調理器具、食品加工場内もしくは厨房内の設備の殺菌方法あるいは殺菌洗浄方法
TWI434926B (zh) * 2006-12-11 2014-04-21 Alcon Res Ltd 眼用組成物中聚氧化乙烯-聚氧化丁烯（ｐｅｏ-ｐｂｏ）嵌段共聚物之使用
US8759321B2 (en) * 2007-06-13 2014-06-24 Bausch & Lomb Incorporated Ophthalmic composition with hyaluronic acid and polymeric biguanide
FR2928519B1 (fr) * 2008-03-13 2012-12-21 Ogf Nouvelle composition pour la conservation des tissus
US8093352B2 (en) * 2008-08-05 2012-01-10 Alcon Research, Ltd. Polyalkylene oxide polyquaternary ammonium biocides
CN102186908B (zh) 2008-09-19 2013-10-16 3M创新有限公司 配体接枝官能化基材
US20100086513A1 (en) * 2008-09-30 2010-04-08 Oliveira Marcos A Method for Effecting Antimicrobial Activity Using Polyamine Analogues
US8431751B1 (en) 2008-12-24 2013-04-30 Alcon Research, Ltd. Polymeric quaternary ammonium compounds with vicinal hydroxy groups
TW201105369A (en) 2009-05-29 2011-02-16 Alcon Res Ltd N-halamine formulations with enhanced antimicrobial activity
TWI547522B (zh) * 2009-07-07 2016-09-01 愛爾康研究有限公司 環氧乙烷環氧丁烷嵌段共聚物組成物
US8999312B2 (en) 2010-06-02 2015-04-07 Alcon Research, Ltd. Use of PBO-PEO-PBO block copolymers in ophthalmic compositions
JP2022506555A (ja) 2018-11-08 2022-01-17 チェン ファン－シン トリス置換ビグアニド化合物およびその使用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3270036A (en) * 1965-10-07 1966-08-30 Squibb & Sons Inc Adamantylbiguanides
GB1351025A (en) 1971-08-20 1974-04-24 Aron Md Samuel J Oxadiazol-5-yl biguanide derivatives method for their preparation and pharmaceutical compositions containing them
DE3169105D1 (en) 1980-12-18 1985-03-28 Smith & Nephew Ass Lens sterilising solutions and their use
US4407791A (en) 1981-09-28 1983-10-04 Alcon Laboratories, Inc. Ophthalmic solutions
GB8312664D0 (en) 1983-05-09 1983-06-15 Ici Plc Bis(1-substituted biguanide)derivatives
US4537746A (en) 1983-12-29 1985-08-27 Bausch & Lomb Incorporated Methods for disinfecting and preserving contact lenses
EP0232250B1 (de) * 1985-07-22 1990-01-31 BAUSCH & LOMB INCORPORATED Verfahren und loesung zur desinfektion und konservierung von kontaktlinsen
US5185337A (en) 1989-03-29 1993-02-09 Otsuka Pharmaceutical Co., Ltd. Pyrroloquinoline derivatives and pharmaceutical compositions for antimicrobial use
KR910011865A (ko) 1989-12-29 1991-08-07 오쓰카 아키히코 세팔로스포린 유도체, 이를 함유하는 항균제 및 이의 제조방법
JPH0426668A (ja) 1990-05-10 1992-01-29 Hb Fuller Licensing & Financing Inc 新規の生物致死組成物
CA2064664C (en) * 1991-04-05 2000-01-11 Hiroshi Ishikawa Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives
TW203128B (en) 1992-06-17 1993-04-01 Ciba Geigy Ag The protection method for hard and soft contact lens
EP0575290B1 (de) 1992-06-17 2006-08-23 Novartis AG Kontaktlinsenpflegemittel für harte und weiche Kontaktlinsen
DE69414836T2 (de) 1993-01-07 1999-06-17 Polymer Technology Corp Schutzmittel für lösungen für kontaktlinsen
WO1994025426A1 (en) 1993-04-28 1994-11-10 Alcon Laboratories, Inc. Diamines as antimicrobial agents and use thereof in ophthalmic composition
US5631005A (en) 1994-09-21 1997-05-20 Alcon Laboratories, Inc. Use of amidoamines in ophthalmic compositions
US5415837A (en) 1993-10-25 1995-05-16 Alcon Laboratories, Inc. Use of diamines to disinfect and clean contact lenses
ZA9811445B (en) 1997-12-19 1999-08-16 Alcon Lab Inc Aminobiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions.

Also Published As

Publication number Publication date
NO20003119D0 (no) 2000-06-16
HK1029290A1 (en) 2001-03-30
ES2226198T3 (es) 2005-03-16
EP1042007A2 (de) 2000-10-11
WO1999032158A3 (en) 1999-09-02
NZ505742A (en) 2002-11-26
TW516960B (en) 2003-01-11
BR9814299A (pt) 2001-10-30
DE69825625T2 (de) 2005-09-15
CA2309172C (en) 2006-07-11
AR016708A1 (es) 2001-07-25
CA2309172A1 (en) 1999-07-01
KR100489905B1 (ko) 2005-05-17
NO20003119L (no) 2000-06-16
KR20010033339A (ko) 2001-04-25
EP1042007B1 (de) 2004-08-11
US6664294B1 (en) 2003-12-16
JP2001526090A (ja) 2001-12-18
AU751002B2 (en) 2002-08-08
JP4027595B2 (ja) 2007-12-26
ZA9811445B (en) 1999-08-16
ATE273031T1 (de) 2004-08-15
AU1941599A (en) 1999-07-12
US20040063791A1 (en) 2004-04-01
WO1999032158A2 (en) 1999-07-01
US6916958B2 (en) 2005-07-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee