ATE309988T1 - Neue pyridin- und quinolin-derivate - Google Patents

Neue pyridin- und quinolin-derivate

Info

Publication number
ATE309988T1
ATE309988T1 AT03704539T AT03704539T ATE309988T1 AT E309988 T1 ATE309988 T1 AT E309988T1 AT 03704539 T AT03704539 T AT 03704539T AT 03704539 T AT03704539 T AT 03704539T AT E309988 T1 ATE309988 T1 AT E309988T1
Authority
AT
Austria
Prior art keywords
quinoline derivatives
new pyridine
pyridine
new
quinoline
Prior art date
Application number
AT03704539T
Other languages
English (en)
Inventor
Markus Boehringer
Bernd Michael Loeffler
Jens-Uwe Peters
Claus Riemer
Peter Weiss
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE309988T1 publication Critical patent/ATE309988T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • C07D221/06Ring systems of three rings
    • C07D221/16Ring systems of three rings containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
AT03704539T 2002-02-13 2003-02-05 Neue pyridin- und quinolin-derivate ATE309988T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02003115 2002-02-13
PCT/EP2003/001112 WO2003068748A1 (en) 2002-02-13 2003-02-05 Novel pyridine- and quinoline-derivatives

Publications (1)

Publication Number Publication Date
ATE309988T1 true ATE309988T1 (de) 2005-12-15

Family

ID=27675615

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03704539T ATE309988T1 (de) 2002-02-13 2003-02-05 Neue pyridin- und quinolin-derivate

Country Status (21)

Country Link
US (1) US6800650B2 (de)
EP (1) EP1476429B1 (de)
JP (1) JP4216197B2 (de)
KR (1) KR100618752B1 (de)
CN (1) CN1308311C (de)
AR (1) AR038419A1 (de)
AT (1) ATE309988T1 (de)
AU (1) AU2003206834B2 (de)
BR (1) BR0307576A (de)
CA (1) CA2474460C (de)
DE (1) DE60302336T2 (de)
ES (1) ES2252656T3 (de)
GT (1) GT200300038A (de)
MX (1) MXPA04007743A (de)
PA (1) PA8566201A1 (de)
PE (1) PE20030922A1 (de)
PL (1) PL372488A1 (de)
RU (1) RU2285693C2 (de)
TW (1) TW200303303A (de)
UY (1) UY27666A1 (de)
WO (1) WO2003068748A1 (de)

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JP5379692B2 (ja) 2006-11-09 2013-12-25 プロビオドルグ エージー 潰瘍、癌及び他の疾患の治療のためのグルタミニルシクラーゼの阻害薬としての3−ヒドロキシ−1,5−ジヒドロ−ピロール−2−オン誘導体
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Also Published As

Publication number Publication date
WO2003068748A9 (en) 2004-10-07
BR0307576A (pt) 2005-01-11
PL372488A1 (en) 2005-07-25
AU2003206834A1 (en) 2003-09-04
US20030195188A1 (en) 2003-10-16
DE60302336D1 (de) 2005-12-22
UY27666A1 (es) 2003-08-29
PE20030922A1 (es) 2003-11-08
CN1308311C (zh) 2007-04-04
DE60302336T2 (de) 2006-08-03
KR100618752B1 (ko) 2006-08-31
EP1476429A1 (de) 2004-11-17
AR038419A1 (es) 2005-01-12
GT200300038A (es) 2003-09-23
JP4216197B2 (ja) 2009-01-28
RU2004127578A (ru) 2005-08-10
PA8566201A1 (es) 2003-12-19
TW200303303A (en) 2003-09-01
US6800650B2 (en) 2004-10-05
CN1630639A (zh) 2005-06-22
AU2003206834B2 (en) 2006-10-19
ES2252656T3 (es) 2006-05-16
MXPA04007743A (es) 2004-10-15
RU2285693C2 (ru) 2006-10-20
JP2005526034A (ja) 2005-09-02
EP1476429B1 (de) 2005-11-16
WO2003068748A1 (en) 2003-08-21
CA2474460A1 (en) 2003-08-21
KR20040081788A (ko) 2004-09-22
CA2474460C (en) 2009-12-22

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