ATE255409T1 - Cisplatinhaltige mikrogranulate - Google Patents

Cisplatinhaltige mikrogranulate

Info

Publication number
ATE255409T1
ATE255409T1 AT98908157T AT98908157T ATE255409T1 AT E255409 T1 ATE255409 T1 AT E255409T1 AT 98908157 T AT98908157 T AT 98908157T AT 98908157 T AT98908157 T AT 98908157T AT E255409 T1 ATE255409 T1 AT E255409T1
Authority
AT
Austria
Prior art keywords
cisplates
microgranules containing
microgranules
containing cisplates
Prior art date
Application number
AT98908157T
Other languages
German (de)
English (en)
Inventor
Patrice Debregeas
Gerard Leduc
Pascal Oury
Pascal Suplie
Original Assignee
Ethypharm Lab Prod Ethiques
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethypharm Lab Prod Ethiques filed Critical Ethypharm Lab Prod Ethiques
Application granted granted Critical
Publication of ATE255409T1 publication Critical patent/ATE255409T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98908157T 1997-02-11 1998-02-10 Cisplatinhaltige mikrogranulate ATE255409T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9701545A FR2759293B1 (fr) 1997-02-11 1997-02-11 Microgranules contenant du cisplatine, procede de fabrication, preparation pharmaceutique et utilisation en polychimiotherapie ou en association avec une radiotherapie
PCT/FR1998/000251 WO1998034599A1 (fr) 1997-02-11 1998-02-10 Microgranules contenant du cisplatine

Publications (1)

Publication Number Publication Date
ATE255409T1 true ATE255409T1 (de) 2003-12-15

Family

ID=9503556

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98908157T ATE255409T1 (de) 1997-02-11 1998-02-10 Cisplatinhaltige mikrogranulate

Country Status (24)

Country Link
US (2) US6458389B1 (OSRAM)
EP (1) EP0971702B1 (OSRAM)
JP (1) JP4549445B2 (OSRAM)
KR (1) KR100471672B1 (OSRAM)
AR (1) AR011133A1 (OSRAM)
AT (1) ATE255409T1 (OSRAM)
BG (1) BG64247B1 (OSRAM)
BR (1) BR9807319A (OSRAM)
CA (1) CA2282082C (OSRAM)
DE (1) DE69820239T2 (OSRAM)
DK (1) DK0971702T3 (OSRAM)
EA (1) EA001760B1 (OSRAM)
ES (1) ES2210726T3 (OSRAM)
FR (1) FR2759293B1 (OSRAM)
HU (1) HU225425B1 (OSRAM)
IL (1) IL131326A (OSRAM)
IN (1) IN187998B (OSRAM)
NO (1) NO323230B1 (OSRAM)
NZ (1) NZ337216A (OSRAM)
PL (1) PL191631B1 (OSRAM)
PT (1) PT971702E (OSRAM)
TW (1) TW561055B (OSRAM)
WO (1) WO1998034599A1 (OSRAM)
ZA (1) ZA981123B (OSRAM)

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US20050096304A1 (en) * 1998-09-08 2005-05-05 David White Method of treating cancer using dithiocarbamate derivatives
FR2790668B1 (fr) * 1999-03-12 2002-07-26 D B F Granules contenant une substance vegetale et leur procede de preparation
WO2000069414A2 (fr) * 1999-05-17 2000-11-23 D.B.F. Granules contenant une substance vegetale et leur procede de preparation
CN1874764B (zh) * 2003-10-10 2012-08-01 埃法尔姆公司 含有银杏提取物的持续释放微粒及其制备方法
FR2861990B1 (fr) 2003-11-10 2006-02-10 Nouveaux Produits Pharma Comprimes faiblement doses a reseau de polymeres
DK1817013T3 (da) * 2004-11-18 2008-10-13 Brystol Myers Squibb Company Enterisk coatet kugle omfattende Ixabepilon
JPWO2006062072A1 (ja) * 2004-12-10 2008-08-07 テムリック株式会社 転移癌治療剤および癌転移抑制剤
US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
FR2918566B1 (fr) 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
FR2918567B1 (fr) * 2007-07-11 2012-08-03 Pf Medicament Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine.
CA2699224C (en) * 2007-09-21 2014-12-16 Evonik Roehm Gmbh Ph-dependent controlled release pharmaceutical composition for non-opioids with resistance against the influence of ethanol
ES2393934T3 (es) * 2007-09-21 2013-01-02 Evonik Röhm Gmbh Composición farmacéutica opioide de lberación controlada dependiente del PH con resitencia frente a la influencia del etanol
HUE034848T2 (en) * 2008-01-10 2018-03-28 Evonik Roehm Gmbh Coated pharmaceutical or nutraceutical preparation with enhanced active substance release in the colon
MX2010007578A (es) * 2008-01-10 2010-08-03 Evonik Roehm Gmbh Preparacion nutriceutica o farmaceutica revestida con una liberacion acelerada controlada de sustancia activa.
DK177529B1 (en) * 2009-10-23 2013-09-08 Bio Bedst Aps Liposomes with improved storage stability
CA2688202C (en) * 2009-12-11 2012-11-13 Bj Services Company Viscoelastic fluids containing hydroxyethyl cellulose
EP2371356B1 (en) * 2010-03-12 2012-12-19 Phoeme GmbH Multi-particle pharmaceutical formulation for colon absorption
US8070047B1 (en) * 2010-12-02 2011-12-06 Rohm And Haas Electronic Materials Llc Flux composition and method of soldering
CA2883703C (en) 2012-09-04 2021-10-19 Eleison Pharmaceuticals, Llc Preventing pulmonary recurrence of cancer with lipid-complexed cisplatin
JP6487534B2 (ja) 2014-09-05 2019-03-20 シンビオミックス セラピューティクス、エルエルシー 細菌性膣炎の治療に使用するためのセクニダゾール
WO2016169042A1 (en) * 2015-04-24 2016-10-27 Genedia Biotech Co. Ltd. Combination therapies for bladder cancer
US11253501B2 (en) 2015-06-01 2022-02-22 Lupin Inc. Secnidazole formulations and use in treating bacterial vaginosis
DK3307239T3 (da) 2015-06-12 2020-11-23 Vaxart Inc Formuleringer til indgivelse af RSV- og norovirusantigener i tyndtarmen
TWI795462B (zh) 2017-11-17 2023-03-11 日商鹽野義製藥股份有限公司 光安定性及溶出性優異的醫藥製劑
CN112236146B (zh) * 2018-04-24 2025-04-15 盐野义制药株式会社 稳定性优良的固体制剂
IL278161B2 (en) * 2018-04-24 2024-12-01 Shionogi & Co Solid dosage form with excellent stability
US12280037B2 (en) 2020-09-22 2025-04-22 Evofem Biosciences, Inc. Method and pharmaceutical composition for treating or preventing trichomoniasis and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE15971T1 (de) * 1981-03-11 1985-10-15 Mirko Beljanski Serpentin, alstonin und sempervirin, medikamente, die die tumor- und krebszellen spezifisch hemmen.
IT1153974B (it) * 1982-09-23 1987-01-21 Erba Farmitalia Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento
DE3421468A1 (de) * 1984-06-08 1985-12-19 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Lipidnanopellets als traegersystem fuer arzneimittel zur peroralen anwendung
DE3523454A1 (de) * 1985-07-01 1987-01-08 Eberhard Prof Dr Nuernberg Formkoerper
US4925674A (en) * 1988-08-25 1990-05-15 Himedics, Inc. Amoxicillin microencapsulated granules
US5399363A (en) * 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
JPH05294839A (ja) * 1992-04-20 1993-11-09 Biomaterial Universe Kk シスプラチン含有生体内分解吸収性高分子の微小球お よびその製造法
US5795882A (en) * 1992-06-22 1998-08-18 Bone Care International, Inc. Method of treating prostatic diseases using delayed and/or sustained release vitamin D formulations
JPH07112932A (ja) * 1993-08-27 1995-05-02 Mitsui Toatsu Chem Inc 徐放性医薬製剤
JPH0789849A (ja) * 1993-09-20 1995-04-04 Fujisawa Pharmaceut Co Ltd 徐放性製剤
JPH0859460A (ja) * 1994-08-22 1996-03-05 Tanaka Kikinzoku Kogyo Kk 抗ガン剤内包キトサンミクロスフェア及びその製造法
US5637319A (en) * 1995-03-01 1997-06-10 Takada; Kanji Controlled-release preparations
US5614206A (en) * 1995-03-07 1997-03-25 Wright Medical Technology, Inc. Controlled dissolution pellet containing calcium sulfate
DK0929293T3 (da) * 1996-08-23 2004-02-02 Sequus Pharm Inc Liposomer indeholdende en cisplatinforbindelse

Also Published As

Publication number Publication date
EA199900734A1 (ru) 2000-04-24
ZA981123B (en) 1998-08-20
EP0971702B1 (fr) 2003-12-03
US20030017210A1 (en) 2003-01-23
ES2210726T3 (es) 2004-07-01
JP4549445B2 (ja) 2010-09-22
DE69820239T2 (de) 2004-10-07
HU225425B1 (en) 2006-11-28
AR011133A1 (es) 2000-08-02
KR100471672B1 (ko) 2005-03-07
IN187998B (OSRAM) 2002-08-03
HUP0001719A3 (en) 2005-11-28
DK0971702T3 (da) 2004-04-13
PL335107A1 (en) 2000-04-10
FR2759293A1 (fr) 1998-08-14
HUP0001719A2 (hu) 2000-11-28
CA2282082C (fr) 2005-10-18
PL191631B1 (pl) 2006-06-30
NO323230B1 (no) 2007-02-05
BR9807319A (pt) 2000-04-18
NO993881L (no) 1999-09-29
DE69820239D1 (de) 2004-01-15
KR20000070997A (ko) 2000-11-25
CA2282082A1 (fr) 1998-08-13
US6458389B1 (en) 2002-10-01
EA001760B1 (ru) 2001-08-27
IL131326A (en) 2005-03-20
TW561055B (en) 2003-11-11
NO993881D0 (no) 1999-08-11
BG64247B1 (bg) 2004-07-30
PT971702E (pt) 2004-04-30
AU744001B2 (en) 2002-02-14
NZ337216A (en) 2000-09-29
WO1998034599A1 (fr) 1998-08-13
FR2759293B1 (fr) 1999-04-30
AU6626798A (en) 1998-08-26
BG103647A (en) 2000-03-31
IL131326A0 (en) 2001-01-28
JP2001512433A (ja) 2001-08-21
EP0971702A1 (fr) 2000-01-19

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