ATA909480A - Verfahren zum herstellen von neuen carbostyrilderivaten und ihren salzen - Google Patents

Verfahren zum herstellen von neuen carbostyrilderivaten und ihren salzen

Info

Publication number
ATA909480A
ATA909480A AT0909480A AT909480A ATA909480A AT A909480 A ATA909480 A AT A909480A AT 0909480 A AT0909480 A AT 0909480A AT 909480 A AT909480 A AT 909480A AT A909480 A ATA909480 A AT A909480A
Authority
AT
Austria
Prior art keywords
salts
producing new
carbostyril derivatives
new carbostyril
derivatives
Prior art date
Application number
AT0909480A
Other languages
English (en)
Other versions
AT381493B (de
Inventor
Takao Nishi
Tatsuyoshi Tanaka
Kazuyuki Nakagawa
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Priority to AT0066885A priority Critical patent/AT383594B/de
Publication of ATA909480A publication Critical patent/ATA909480A/de
Application granted granted Critical
Publication of AT381493B publication Critical patent/AT381493B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/04—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
AT0909480A 1980-02-29 1980-06-04 Verfahren zum herstellen von neuen carbostyrilderivaten und ihren salzen AT381493B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT0066885A AT383594B (de) 1980-02-29 1985-03-06 Verfahren zum herstellen von neuen carbostyrilderivaten und ihren salzen

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2565880A JPS56122356A (en) 1980-02-29 1980-02-29 Carbostyril derivative
PCT/JP1980/000122 WO1981002421A1 (en) 1980-02-29 1980-06-04 Carbostyryl derivatives

Publications (2)

Publication Number Publication Date
ATA909480A true ATA909480A (de) 1986-03-15
AT381493B AT381493B (de) 1986-10-27

Family

ID=12171902

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0909480A AT381493B (de) 1980-02-29 1980-06-04 Verfahren zum herstellen von neuen carbostyrilderivaten und ihren salzen

Country Status (24)

Country Link
US (1) US4435404A (de)
JP (1) JPS56122356A (de)
KR (2) KR860002099B1 (de)
AT (1) AT381493B (de)
AU (1) AU532319B2 (de)
BE (1) BE883713A (de)
CA (1) CA1159068A (de)
CH (1) CH647765A5 (de)
DE (1) DE3049959T1 (de)
DK (1) DK151956C (de)
ES (1) ES492230A0 (de)
FI (1) FI76321C (de)
FR (1) FR2477149A1 (de)
GB (1) GB2070588B (de)
IT (1) IT1129812B (de)
MX (1) MX6752E (de)
NL (1) NL185146C (de)
NO (1) NO160512C (de)
PH (1) PH18532A (de)
PT (1) PT71359B (de)
SE (1) SE461147B (de)
SU (2) SU1169535A3 (de)
WO (1) WO1981002421A1 (de)
ZA (1) ZA803322B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4578381A (en) * 1982-07-05 1986-03-25 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
DE3434271A1 (de) * 1984-09-19 1986-03-20 Beiersdorf Ag, 2000 Hamburg Substituierte 3,4-dihydro-chinolin-2(1h)-one verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
JP2753622B2 (ja) 1988-05-02 1998-05-20 大塚製薬株式会社 カルボスチリル誘導体
US5227381A (en) * 1988-05-02 1993-07-13 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivative
WO1993004042A1 (fr) * 1991-08-23 1993-03-04 Otsuka Pharmaceutical Co., Ltd. Derive de carbostyrile et antiagregant plaquettaire
JP2686887B2 (ja) * 1992-08-11 1997-12-08 キッセイ薬品工業株式会社 ピペリジノ−３，４−ジヒドロカルボスチリル誘導体
US7208497B2 (en) 2001-07-02 2007-04-24 Novo Nordisk A/S Substituted piperazines and diazepanes
US8796447B2 (en) 2009-08-21 2014-08-05 Otsuka Pharmaceutical Co., Ltd. Process for producing benzo[B][1,4]diazepine-2,4-dione compound
TWI481601B (zh) * 2009-08-21 2015-04-21 Otsuka Pharma Co Ltd 含氮化合物及藥學組成物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1021522A (en) * 1963-05-10 1966-03-02 Ici Ltd 2-quinolone derivatives
DE1527937A1 (de) * 1966-12-10 1969-11-13 Blanc & Co Verfahren zur Herstellung eines sich konisch verjuengenden,einen nach aussen abgewinkelten flachen Rand aufweisenden Hohlteils sowie Einrichtung zur Durchfuehrung des Verfahrens
JPS48103590A (de) * 1972-04-13 1973-12-25
JPS5082218A (de) * 1973-11-10 1975-07-03
JPS5310988B2 (de) * 1974-04-25 1978-04-18
JPS5318030B2 (de) * 1974-05-20 1978-06-13
FI59246C (fi) * 1974-06-24 1981-07-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av benscykloamidderivat anvaendbara vid trombos- och emboliterapin
US4313947A (en) 1974-06-24 1982-02-02 Otsuka Pharmaceutical Co., Ltd. Platelet aggregation inhibiting 2-oxyindoles, their compositions and method of use
US4081447A (en) * 1975-04-09 1978-03-28 Abbott Laboratories 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof
JPS5273879A (en) * 1975-12-18 1977-06-21 Otsuka Pharmaceut Co Ltd Synthesis of ester derivatives
IE46852B1 (en) 1977-06-10 1983-10-05 Otsuka Pharma Co Ltd Novel carbostyril derivatives
JPS545981A (en) * 1977-06-10 1979-01-17 Otsuka Pharmaceut Co Ltd Carbostyryl derivatives

Also Published As

Publication number Publication date
NO160512C (no) 1989-04-26
PT71359A (en) 1980-07-01
AU532319B2 (en) 1983-09-22
ES8105290A1 (es) 1981-05-16
NO160512B (no) 1989-01-16
AU5985980A (en) 1981-09-11
MX6752E (es) 1986-06-25
GB2070588B (en) 1983-10-19
CH647765A5 (de) 1985-02-15
JPS56122356A (en) 1981-09-25
NO813477L (no) 1981-10-15
SU1169535A3 (ru) 1985-07-23
FI801843A (fi) 1981-08-30
WO1981002421A1 (en) 1981-09-03
AT381493B (de) 1986-10-27
DK250381A (da) 1981-09-03
JPS6334845B2 (de) 1988-07-12
KR840004681A (ko) 1984-10-22
BE883713A (fr) 1980-12-09
SE8102690L (sv) 1981-08-30
NL8020199A (nl) 1981-12-01
PH18532A (en) 1985-08-09
KR860002100B1 (ko) 1986-11-25
DE3049959C2 (de) 1993-07-08
FR2477149A1 (fr) 1981-09-04
IT8067888A0 (it) 1980-06-06
NL185146B (nl) 1989-09-01
SE461147B (sv) 1990-01-15
DK151956C (da) 1988-08-15
SU1395140A3 (ru) 1988-05-07
US4435404A (en) 1984-03-06
NL185146C (nl) 1990-02-01
ZA803322B (en) 1982-01-27
ES492230A0 (es) 1981-05-16
FI76321B (fi) 1988-06-30
DK151956B (da) 1988-01-18
DE3049959T1 (de) 1982-07-29
GB2070588A (en) 1981-09-09
KR860002099B1 (ko) 1986-11-25
FR2477149B1 (de) 1983-06-24
FI76321C (fi) 1988-10-10
IT1129812B (it) 1986-06-11
CA1159068A (en) 1983-12-20
KR830002713A (ko) 1983-05-30
PT71359B (en) 1981-10-21

Similar Documents

Publication Publication Date Title
AT376208B (de) Verfahren zum herstellen von neuen piperidinderivaten und deren salzen
AT376207B (de) Verfahren zum herstellen von neuen piperidinderivaten und deren saeureadditionssalzen
AT381701B (de) Verfahren zur herstellung von neuen carbostyrilverbindungen und ihren pharmazeutisch annehmbaren salzen
AT385506B (de) Verfahren zur herstellung von neuen carbostyrilderivaten und deren salzen
AT374458B (de) Verfahren zum herstellen von neuen piperidinderivaten und deren salzen
AT355029B (de) Verfahren zum herstellen von neuen 3,4-dihydro- chinazolinen und ihren salzen und isomeren
AT355206B (de) Verfahren zum herstellen von neuen derivaten der 7-acylamido-3-cephem-4-carbonsaeure und ihren salzen
AT368512B (de) Verfahren zum herstellen von neuen heterocyclischen derivaten von oxyiminosubstituierten cephalosporinen, ihren salzen und ihren isomeren
AT376210B (de) Verfahren zum herstellen von neuen benzimidazolderivaten und von estern und salzen hievon
AT373258B (de) Verfahren zum herstellen von neuen 4-alkyl-8aminoalkyl-psoralenen
ATA909480A (de) Verfahren zum herstellen von neuen carbostyrilderivaten und ihren salzen
AT370095B (de) Verfahren zum herstellen von neuen 1-aryl-alkyl-imidazolderivaten und deren salzen
AT379804B (de) Verfahren zur herstellung von neuen phenaethylimidazolderivaten und von deren salzen
AT374470B (de) Verfahren zur herstellung von neuen piperazinderivaten und ihren salzen
ATA238481A (de) Verfahren zur herstellung von neuen acylaminophenylpyridinderivaten und deren salzen
ATA66885A (de) Verfahren zum herstellen von neuen carbostyrilderivaten und ihren salzen
AT363931B (de) Verfahren zum herstellen von neuen substituierten 2-cyclopropyl-chromonen, ihren salzen und isomeren
AT381320B (de) Verfahren zum herstellen von neuen (amido)-nsubstituierten bleomycinen und ihren salzen
AT379591B (de) Verfahren zur herstellung von neuen thiazolidinderivaten und von deren salzen und isomeren
AT371809B (de) Verfahren zum herstellen von neuen chinazolinen und ihren salzen
AT380021B (de) Verfahren zum herstellen von neuen aminopropylaminobleomycinderivaten
ATA485081A (de) Verfahren zum herstellen von neuen chinazolinen und ihren salzen
AT369730B (de) Verfahren zum herstellen von neuen basischen p-chloracetophenonoximaethern
ATA507181A (de) Verfahren zum herstellen von neuen 1-arylalkyl-imidazolderivaten und deren salzen
ATA426181A (de) Verfahren zum herstellen von neuen heterocyclischen derivaten von oxyiminosubstituierten cephalosporinen, ihren salzen und ihren isomeren

Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee