AR005197A1 - Derivados de taxoides, su preparacion y composiciones farmaceuticas que los contienen - Google Patents

Derivados de taxoides, su preparacion y composiciones farmaceuticas que los contienen

Info

Publication number
AR005197A1
AR005197A1 ARP960105851A ARP960105851A AR005197A1 AR 005197 A1 AR005197 A1 AR 005197A1 AR P960105851 A ARP960105851 A AR P960105851A AR P960105851 A ARP960105851 A AR P960105851A AR 005197 A1 AR005197 A1 AR 005197A1
Authority
AR
Argentina
Prior art keywords
preparation
pharmaceutical compositions
taxoids
derivatives
contain
Prior art date
Application number
ARP960105851A
Other languages
English (en)
Spanish (es)
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of AR005197A1 publication Critical patent/AR005197A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ARP960105851A 1995-12-22 1996-12-20 Derivados de taxoides, su preparacion y composiciones farmaceuticas que los contienen AR005197A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9515379A FR2742751B1 (fr) 1995-12-22 1995-12-22 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
AR005197A1 true AR005197A1 (es) 1999-04-14

Family

ID=9485871

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960105851A AR005197A1 (es) 1995-12-22 1996-12-20 Derivados de taxoides, su preparacion y composiciones farmaceuticas que los contienen

Country Status (40)

Country Link
US (1) US5728849A (en0)
EP (1) EP0876362B1 (en0)
JP (1) JP3953106B2 (en0)
KR (1) KR100500351B1 (en0)
CN (1) CN1103766C (en0)
AR (1) AR005197A1 (en0)
AT (1) ATE250593T1 (en0)
AU (1) AU712597B2 (en0)
BG (1) BG63204B1 (en0)
BR (1) BR9612135A (en0)
CA (1) CA2238884C (en0)
CO (1) CO4520184A1 (en0)
CZ (1) CZ294972B6 (en0)
DE (1) DE69630145T2 (en0)
DK (1) DK0876362T3 (en0)
DZ (1) DZ2149A1 (en0)
EA (1) EA001533B1 (en0)
ES (1) ES2202490T3 (en0)
FR (1) FR2742751B1 (en0)
HU (1) HU225032B1 (en0)
IL (1) IL124994A (en0)
IN (4) IN186768B (en0)
MA (1) MA26412A1 (en0)
MX (1) MX9804688A (en0)
MY (1) MY113934A (en0)
NO (1) NO317358B1 (en0)
NZ (1) NZ324337A (en0)
OA (1) OA10700A (en0)
PE (1) PE25198A1 (en0)
PL (1) PL189311B1 (en0)
PT (1) PT876362E (en0)
RO (1) RO116194B1 (en0)
SK (1) SK282835B6 (en0)
TN (1) TNSN96169A1 (en0)
TR (1) TR199801179T2 (en0)
TW (1) TW371659B (en0)
UA (1) UA48205C2 (en0)
UY (1) UY24386A1 (en0)
WO (1) WO1997023473A1 (en0)
ZA (1) ZA9610737B (en0)

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GB9920548D0 (en) * 1999-08-31 1999-11-03 Rhone Poulenc Rorer Sa Treatment of hepatocellular carcinoma
BR0104779A (pt) 2000-02-02 2001-12-26 Univ Florida State Res Found Taxanos substituìdos com carbonato c10 comoagentes antitumor
HRPK20110926B3 (hr) * 2001-02-24 2013-05-31 Boehringer Ingelheim Pharma Gmbh & Co.Kg. Derivati ksantina, njihova proizvodnja i upotreba kao lijekova
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
EP1663153A4 (en) * 2003-05-20 2011-01-05 Aronex Pharmaceuticals Inc COMBINATION SCHEMOTHERAPY WITH A LIPOSOMAL PLATINUM COMPLEX
US7501426B2 (en) 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
EP1669358A1 (en) * 2004-12-07 2006-06-14 Aventis Pharma S.A. Cytotoxic agents comprising new taxanes
DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
NO347644B1 (no) 2006-05-04 2024-02-12 Boehringer Ingelheim Int Polymorfer
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
US20080207743A1 (en) * 2007-02-28 2008-08-28 Rodger Lamb Biologically Active Taxane Analogs and Methods of Treatment
KR101610005B1 (ko) * 2007-08-17 2016-04-08 베링거 인겔하임 인터내셔날 게엠베하 Ｆａｂ 관련 질환의 치료에 사용하기 위한 푸린 유도체
AR071175A1 (es) 2008-04-03 2010-06-02 Boehringer Ingelheim Int Composicion farmaceutica que comprende un inhibidor de la dipeptidil-peptidasa-4 (dpp4) y un farmaco acompanante
PE20100156A1 (es) * 2008-06-03 2010-02-23 Boehringer Ingelheim Int Tratamiento de nafld
BRPI0916997A2 (pt) 2008-08-06 2020-12-15 Boehringer Ingelheim International Gmbh Inibidor de dpp-4 e seu uso
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
EP2326326B1 (en) * 2008-08-15 2019-10-09 Boehringer Ingelheim International GmbH Dpp-4 inhibitors for use for the treatment of wound healing in diabetic patients
CN102149407A (zh) 2008-09-10 2011-08-10 贝林格尔.英格海姆国际有限公司 治疗糖尿病和相关病症的组合疗法
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
AU2009331471B2 (en) 2008-12-23 2015-09-03 Boehringer Ingelheim International Gmbh Salt forms of organic compound
AR074990A1 (es) 2009-01-07 2011-03-02 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
PH12012501037A1 (en) 2009-11-27 2013-01-14 Boehringer Ingelheim Int Treatment of genotyped diabetic patients with dpp-iv inhibitors such as linagliptin
BR112012028136A2 (pt) 2010-05-05 2016-08-09 Boehringer Ingelheim Int terapia de combinaçao
AU2011268940B2 (en) 2010-06-24 2015-05-21 Boehringer Ingelheim International Gmbh Diabetes therapy
US9034883B2 (en) 2010-11-15 2015-05-19 Boehringer Ingelheim International Gmbh Vasoprotective and cardioprotective antidiabetic therapy
EA030121B1 (ru) 2011-07-15 2018-06-29 Бёрингер Ингельхайм Интернациональ Гмбх Замещенные хиназолины, их получение и их применение в фармацевтических композициях
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
EP4151218A1 (en) 2012-05-14 2023-03-22 Boehringer Ingelheim International GmbH Linagliptin, a xanthine derivative as dpp-4 inhibitor, for use in the treatment of sirs and/or sepsis
JP6224084B2 (ja) 2012-05-14 2017-11-01 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 糸球体上皮細胞関連障害及び／又はネフローゼ症候群の治療に用いるｄｐｐ−４阻害薬としてのキサンチン誘導体
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
ES2701076T3 (es) 2012-11-24 2019-02-20 Hangzhou Dac Biotech Co Ltd Enlazadores hidrofílicos y sus usos para la conjugación de fármacos a las moléculas que se unen a las células
FR3010839B1 (fr) * 2013-09-17 2017-04-21 Schneider Electric Ind Sas Dispositif de raccordement electrique d'au moins un conducteur dans une borne appartenant a un appareil electrique
ES2960619T3 (es) 2014-02-28 2024-03-05 Hangzhou Dac Biotech Co Ltd Enlazadores cargados y sus usos para la conjugación
ES2950384T3 (es) 2014-02-28 2023-10-09 Boehringer Ingelheim Int Uso médico de un inhibidor de DPP-4
CA2991973C (en) 2015-07-12 2021-12-07 Suzhou M-Conj Biotech Co., Ltd. Bridge linkers for conjugation of a cell-binding molecule
US9839687B2 (en) 2015-07-15 2017-12-12 Suzhou M-Conj Biotech Co., Ltd. Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
JP2019517542A (ja) 2016-06-10 2019-06-24 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング リナグリプチンおよびメトホルミンの組合せ
MX2019005583A (es) 2016-11-14 2019-10-21 Hangzhou Dac Biotech Co Ltd Vinculantes de conjugacion, conjugados de molecula de union a celulas que contienen los vinculantes, metodos de creacion y usos de dichos conjugados con los vinculantes.
EP4426727A2 (en) 2021-11-03 2024-09-11 Hangzhou Dac Biotech Co., Ltd. Specific conjugation of an antibody

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2017724C1 (ru) * 1990-07-12 1994-08-15 Дзе Юниверсити оф Канзас Способ получения производных таксола
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
FR2678930B1 (fr) * 1991-07-10 1995-01-13 Rhone Poulenc Rorer Sa Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.
RU2059631C1 (ru) * 1991-11-29 1996-05-10 Дзе Юниверсити оф Канзас Производные таксола и фармацевтическая композиция, обладающая противоопухолевой активностью
DE69325454T2 (de) * 1992-04-17 2000-01-20 Abbott Laboratories, Abbott Park Taxol-derivate
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
MX9307777A (es) * 1992-12-15 1994-07-29 Upjohn Co 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.

Also Published As

Publication number Publication date
HUP9904046A1 (hu) 2001-04-28
TR199801179T2 (xx) 1998-10-21
PE25198A1 (es) 1998-05-10
NZ324337A (en) 2000-03-27
DE69630145D1 (de) 2003-10-30
EA001533B1 (ru) 2001-04-23
IN188470B (en0) 2002-09-28
BG102569A (en) 1999-04-30
HU225032B1 (en) 2006-05-29
TNSN96169A1 (fr) 2005-03-15
OA10700A (fr) 2002-11-27
IN188680B (en0) 2002-10-26
UA48205C2 (uk) 2002-08-15
IL124994A (en) 2000-12-06
CA2238884C (fr) 2007-02-06
FR2742751A1 (fr) 1997-06-27
AU1180997A (en) 1997-07-17
MA26412A1 (fr) 2004-12-20
ATE250593T1 (de) 2003-10-15
SK282835B6 (sk) 2002-12-03
JP2000502671A (ja) 2000-03-07
HUP9904046A3 (en) 2001-08-28
MY113934A (en) 2002-06-29
CN1103766C (zh) 2003-03-26
KR100500351B1 (ko) 2005-12-21
NO317358B1 (no) 2004-10-18
BG63204B1 (bg) 2001-06-29
WO1997023473A1 (fr) 1997-07-03
FR2742751B1 (fr) 1998-01-30
DE69630145T2 (de) 2004-07-15
TW371659B (en) 1999-10-11
EA199800588A1 (ru) 1998-12-24
UY24386A1 (es) 2001-08-27
CZ196198A3 (cs) 1998-09-16
PL189311B1 (pl) 2005-07-29
CO4520184A1 (es) 1997-10-15
NO982580L (no) 1998-06-05
KR19990076680A (ko) 1999-10-15
CA2238884A1 (fr) 1997-07-03
ZA9610737B (en) 1997-06-27
PT876362E (pt) 2004-02-27
CN1205697A (zh) 1999-01-20
DK0876362T3 (da) 2004-02-02
BR9612135A (pt) 1999-07-13
IN188469B (en0) 2002-09-28
EP0876362A1 (fr) 1998-11-11
IL124994A0 (en) 1999-01-26
IN186768B (en0) 2001-11-03
DZ2149A1 (fr) 2002-10-23
RO116194B1 (ro) 2000-11-30
JP3953106B2 (ja) 2007-08-08
AU712597B2 (en) 1999-11-11
EP0876362B1 (fr) 2003-09-24
NO982580D0 (no) 1998-06-05
SK85398A3 (en) 1998-11-04
HK1017895A1 (en) 1999-12-03
MX9804688A (es) 1998-10-31
PL327405A1 (en) 1998-12-07
ES2202490T3 (es) 2004-04-01
CZ294972B6 (cs) 2005-04-13
US5728849A (en) 1998-03-17

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