CO4520184A1 - Nuevos taxoides, su preparacion y composiciones farmaceuticas que les contienen - Google Patents

Nuevos taxoides, su preparacion y composiciones farmaceuticas que les contienen

Info

Publication number
CO4520184A1
CO4520184A1 CO96067023A CO96067023A CO4520184A1 CO 4520184 A1 CO4520184 A1 CO 4520184A1 CO 96067023 A CO96067023 A CO 96067023A CO 96067023 A CO96067023 A CO 96067023A CO 4520184 A1 CO4520184 A1 CO 4520184A1
Authority
CO
Colombia
Prior art keywords
carbon
atoms
radical
take
alkyl
Prior art date
Application number
CO96067023A
Other languages
English (en)
Inventor
Herve Bouchard
Alain Commercon
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of CO4520184A1 publication Critical patent/CO4520184A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

1. NUEVOS TAXOIDES DE FORMULA GENERAL: FIGURA 1 EN LA QUE Z REPRESENTA UN ATOMO DE HIDROGENO O UN RADICAL DE FORMULA GENERAL: FIGURA 2 EN LA QUE: R1 REPRESENTA UN RADICAL BENCILO EVENTUALMENTE SUSTITUIDO POR UNO O VARIOS ATOMOS O RADICALES, I- DENTICOS O DIFERENTES, ELEGIDOS DE ENTRE LOS ATO- MOS DE HALOGENOS Y LOS RADICALES ALQUILOS QUE CON- TIENEN 1 A 4 ATOMOS DE CARBONO, ALCOXI QUE CONTIE- NE 1 A 4 ATOMOS DE CARBONO O TRIFLUORMETILO, TENI- LO O FURILO O UN RADICAL R2-O-CO EN LA QUE R2 RE- PRESENTA UN RADICAL ALQUILO QUE CONTIENE 1 A 8 A- TOMOS DE CARBONO, ALQUENILO QUE CONTIENE 2 A 8 A- TOMOS DE CARBONO, ALQUINILO QUE CONTIENE 3 A 8 A- TOMOS DE CARBONO, CICLOALQUILO QUE CONTIENE 3 A 6 ATOMOS DE CARBONO, CICLOALQUENILO QUE CONTIENE 4 A 6 ATOMOS DE CARBONO, BICICLOALQUILO QUE CONTIENE DE 7 A 10 ATOMOS DE CARBONO, ESTANDO SUBSTITUIDOS ESTOS RADICALES EVENTUALMENTE POR UNO O VARIOS SUBSTITUYENTES ELEGIDOS DE LOS ATOMOS DE HALOGENO Y LOS RADICALES HIDROXI, ALCOXI QUE CONTIENEN DE 1 A 4 ATOMOS DE CARBONO, DIALQUILAMINO, CADA UNA DE CUYAS PARTES ALQUILO CONTIENE DE 1 A 4 ATOMOS DE CARBONO, PIPERIDINO, MORFOLINO, PIPERAZINILO-1 (E- VENTUALMENTE SUBSTITUIDO EN -4 POR UN RADICAL AL- QUILO QUE CONTIENE DE 1 A 4 ATOMOS DE CARBONO O POR UN RADICAL FENILALQUILO, CUYAS PARTES ALQUILO CONTIENE DE 1 A 4 ATOMOS DE CARBONO), CICLOALQUILO QUE CONTIENE DE 3 A 6 ATOMOS DE CARBONO, CICLOAL- QUENILO QUE CONTIENE DE 4 A 6 ATOMOS DE CARBONO... A
CO96067023A 1995-12-22 1996-12-20 Nuevos taxoides, su preparacion y composiciones farmaceuticas que les contienen CO4520184A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9515379A FR2742751B1 (fr) 1995-12-22 1995-12-22 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
CO4520184A1 true CO4520184A1 (es) 1997-10-15

Family

ID=9485871

Family Applications (1)

Application Number Title Priority Date Filing Date
CO96067023A CO4520184A1 (es) 1995-12-22 1996-12-20 Nuevos taxoides, su preparacion y composiciones farmaceuticas que les contienen

Country Status (41)

Country Link
US (1) US5728849A (es)
EP (1) EP0876362B1 (es)
JP (1) JP3953106B2 (es)
KR (1) KR100500351B1 (es)
CN (1) CN1103766C (es)
AR (1) AR005197A1 (es)
AT (1) ATE250593T1 (es)
AU (1) AU712597B2 (es)
BG (1) BG63204B1 (es)
BR (1) BR9612135A (es)
CA (1) CA2238884C (es)
CO (1) CO4520184A1 (es)
CZ (1) CZ294972B6 (es)
DE (1) DE69630145T2 (es)
DK (1) DK0876362T3 (es)
DZ (1) DZ2149A1 (es)
EA (1) EA001533B1 (es)
ES (1) ES2202490T3 (es)
FR (1) FR2742751B1 (es)
HK (1) HK1017895A1 (es)
HU (1) HU225032B1 (es)
IL (1) IL124994A (es)
IN (4) IN186768B (es)
MA (1) MA26412A1 (es)
MX (1) MX9804688A (es)
MY (1) MY113934A (es)
NO (1) NO317358B1 (es)
NZ (1) NZ324337A (es)
OA (1) OA10700A (es)
PE (1) PE25198A1 (es)
PL (1) PL189311B1 (es)
PT (1) PT876362E (es)
RO (1) RO116194B1 (es)
SK (1) SK282835B6 (es)
TN (1) TNSN96169A1 (es)
TR (1) TR199801179T2 (es)
TW (1) TW371659B (es)
UA (1) UA48205C2 (es)
UY (1) UY24386A1 (es)
WO (1) WO1997023473A1 (es)
ZA (1) ZA9610737B (es)

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ES2733348T3 (es) * 2007-08-17 2019-11-28 Boehringer Ingelheim Int Derivados de purina para uso en el tratamiento de enfermedades relacionadas con FAP
PE20140960A1 (es) 2008-04-03 2014-08-15 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
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UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
KR20200118243A (ko) 2008-08-06 2020-10-14 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
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JP6034781B2 (ja) 2010-05-05 2016-11-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 併用療法
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NZ618698A (en) 2011-07-15 2015-08-28 Boehringer Ingelheim Int Substituted quinazolines, the preparation thereof and the use thereof in pharmaceutical compositions
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
WO2013171167A1 (en) 2012-05-14 2013-11-21 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome
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WO2015151081A2 (en) 2015-07-12 2015-10-08 Suzhou M-Conj Biotech Co., Ltd Bridge linkers for conjugation of a cell-binding molecule
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Also Published As

Publication number Publication date
ATE250593T1 (de) 2003-10-15
CN1205697A (zh) 1999-01-20
JP2000502671A (ja) 2000-03-07
TNSN96169A1 (fr) 2005-03-15
DE69630145D1 (de) 2003-10-30
JP3953106B2 (ja) 2007-08-08
MY113934A (en) 2002-06-29
DK0876362T3 (da) 2004-02-02
PL327405A1 (en) 1998-12-07
AU1180997A (en) 1997-07-17
DE69630145T2 (de) 2004-07-15
PE25198A1 (es) 1998-05-10
NZ324337A (en) 2000-03-27
SK85398A3 (en) 1998-11-04
NO317358B1 (no) 2004-10-18
UA48205C2 (uk) 2002-08-15
OA10700A (fr) 2002-11-27
UY24386A1 (es) 2001-08-27
WO1997023473A1 (fr) 1997-07-03
SK282835B6 (sk) 2002-12-03
CA2238884A1 (fr) 1997-07-03
BG102569A (en) 1999-04-30
NO982580L (no) 1998-06-05
ZA9610737B (en) 1997-06-27
CZ294972B6 (cs) 2005-04-13
FR2742751B1 (fr) 1998-01-30
US5728849A (en) 1998-03-17
FR2742751A1 (fr) 1997-06-27
CZ196198A3 (cs) 1998-09-16
BR9612135A (pt) 1999-07-13
EP0876362A1 (fr) 1998-11-11
HK1017895A1 (en) 1999-12-03
AU712597B2 (en) 1999-11-11
HUP9904046A3 (en) 2001-08-28
TR199801179T2 (xx) 1998-10-21
NO982580D0 (no) 1998-06-05
KR100500351B1 (ko) 2005-12-21
MX9804688A (es) 1998-10-31
CA2238884C (fr) 2007-02-06
BG63204B1 (bg) 2001-06-29
HU225032B1 (en) 2006-05-29
ES2202490T3 (es) 2004-04-01
TW371659B (en) 1999-10-11
EP0876362B1 (fr) 2003-09-24
IN186768B (es) 2001-11-03
CN1103766C (zh) 2003-03-26
IN188469B (es) 2002-09-28
MA26412A1 (fr) 2004-12-20
IN188470B (es) 2002-09-28
EA199800588A1 (ru) 1998-12-24
EA001533B1 (ru) 2001-04-23
AR005197A1 (es) 1999-04-14
HUP9904046A1 (hu) 2001-04-28
IN188680B (es) 2002-10-26
RO116194B1 (ro) 2000-11-30
DZ2149A1 (fr) 2002-10-23
IL124994A0 (en) 1999-01-26
PT876362E (pt) 2004-02-27
PL189311B1 (pl) 2005-07-29
IL124994A (en) 2000-12-06
KR19990076680A (ko) 1999-10-15

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