UY24386A1 - Nuevos taxoides, su preparación y composiciones farmacéuticas que los contienen. - Google Patents

Nuevos taxoides, su preparación y composiciones farmacéuticas que los contienen.

Info

Publication number
UY24386A1
UY24386A1 UY24386A UY24386A UY24386A1 UY 24386 A1 UY24386 A1 UY 24386A1 UY 24386 A UY24386 A UY 24386A UY 24386 A UY24386 A UY 24386A UY 24386 A1 UY24386 A1 UY 24386A1
Authority
UY
Uruguay
Prior art keywords
contain
preparation
pharmaceutical compositions
new taxoids
taxoids
Prior art date
Application number
UY24386A
Other languages
English (en)
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of UY24386A1 publication Critical patent/UY24386A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Composición farmacéutica, caracterizada porque al menos un producto según una de las reivindicaciones 1, 2 o 3, en el que Z representa un radical de fórmula (II), en asociación con uno o varios diluyentes o adyuvantes farmacéuticamente aceptables y, eventualmente, uno o varios compuestos compatibles y farmacológicamente activos.
UY24386A 1995-12-22 2000-12-02 Nuevos taxoides, su preparación y composiciones farmacéuticas que los contienen. UY24386A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9515379A FR2742751B1 (fr) 1995-12-22 1995-12-22 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
UY24386A1 true UY24386A1 (es) 2001-08-27

Family

ID=9485871

Family Applications (1)

Application Number Title Priority Date Filing Date
UY24386A UY24386A1 (es) 1995-12-22 2000-12-02 Nuevos taxoides, su preparación y composiciones farmacéuticas que los contienen.

Country Status (41)

Country Link
US (1) US5728849A (es)
EP (1) EP0876362B1 (es)
JP (1) JP3953106B2 (es)
KR (1) KR100500351B1 (es)
CN (1) CN1103766C (es)
AR (1) AR005197A1 (es)
AT (1) ATE250593T1 (es)
AU (1) AU712597B2 (es)
BG (1) BG63204B1 (es)
BR (1) BR9612135A (es)
CA (1) CA2238884C (es)
CO (1) CO4520184A1 (es)
CZ (1) CZ294972B6 (es)
DE (1) DE69630145T2 (es)
DK (1) DK0876362T3 (es)
DZ (1) DZ2149A1 (es)
EA (1) EA001533B1 (es)
ES (1) ES2202490T3 (es)
FR (1) FR2742751B1 (es)
HK (1) HK1017895A1 (es)
HU (1) HU225032B1 (es)
IL (1) IL124994A (es)
IN (4) IN186768B (es)
MA (1) MA26412A1 (es)
MX (1) MX9804688A (es)
MY (1) MY113934A (es)
NO (1) NO317358B1 (es)
NZ (1) NZ324337A (es)
OA (1) OA10700A (es)
PE (1) PE25198A1 (es)
PL (1) PL189311B1 (es)
PT (1) PT876362E (es)
RO (1) RO116194B1 (es)
SK (1) SK282835B6 (es)
TN (1) TNSN96169A1 (es)
TR (1) TR199801179T2 (es)
TW (1) TW371659B (es)
UA (1) UA48205C2 (es)
UY (1) UY24386A1 (es)
WO (1) WO1997023473A1 (es)
ZA (1) ZA9610737B (es)

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GB9920548D0 (en) * 1999-08-31 1999-11-03 Rhone Poulenc Rorer Sa Treatment of hepatocellular carcinoma
JP2003522171A (ja) 2000-02-02 2003-07-22 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド 抗腫瘍剤としてのｃ１０カーボネート置換タキサン
AU2002234640B8 (en) * 2001-02-24 2009-11-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Xanthine derivative, production and use thereof as a medicament
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
WO2004103344A1 (en) * 2003-05-20 2004-12-02 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising a liposomal platinum complex
US7501426B2 (en) 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
EP1669358A1 (en) * 2004-12-07 2006-06-14 Aventis Pharma S.A. Cytotoxic agents comprising new taxanes
DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
PE20110235A1 (es) 2006-05-04 2011-04-14 Boehringer Ingelheim Int Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
JP5323684B2 (ja) * 2006-05-04 2013-10-23 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 多形体
US20080207743A1 (en) * 2007-02-28 2008-08-28 Rodger Lamb Biologically Active Taxane Analogs and Methods of Treatment
JP5769966B2 (ja) * 2007-08-17 2015-08-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｆａｂ関連疾患治療用プリン誘導体
PE20091730A1 (es) 2008-04-03 2009-12-10 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
PE20100156A1 (es) * 2008-06-03 2010-02-23 Boehringer Ingelheim Int Tratamiento de nafld
KR20200118243A (ko) 2008-08-06 2020-10-14 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
EP2326326B1 (en) * 2008-08-15 2019-10-09 Boehringer Ingelheim International GmbH Dpp-4 inhibitors for use for the treatment of wound healing in diabetic patients
CN102149407A (zh) 2008-09-10 2011-08-10 贝林格尔.英格海姆国际有限公司 治疗糖尿病和相关病症的组合疗法
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
CN107011345A (zh) 2008-12-23 2017-08-04 勃林格殷格翰国际有限公司 有机化合物的盐形式
AR074990A1 (es) 2009-01-07 2011-03-02 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
EP2504002B1 (en) 2009-11-27 2019-10-09 Boehringer Ingelheim International GmbH Treatment of genotyped diabetic patients with dpp-iv inhibitors such as linagliptin
MX341025B (es) 2010-05-05 2016-08-04 Boehringer Ingelheim Int Gmbh * Terapia de combinacion.
NZ603319A (en) 2010-06-24 2015-04-24 Boehringer Ingelheim Int Diabetes therapy
AR083878A1 (es) 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
PL2731947T3 (pl) 2011-07-15 2019-07-31 Boehringer Ingelheim International Gmbh Podstawiona dimeryczna pochodna chinazoliny, sposób jej wytwarzania i jej zastosowanie w kompozycjach farmaceutycznych do leczenia cukrzycy typu I i II
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
US20130303462A1 (en) 2012-05-14 2013-11-14 Boehringer Ingelheim International Gmbh Use of a dpp-4 inhibitor in podocytes related disorders and/or nephrotic syndrome
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
EP2922818B1 (en) 2012-11-24 2018-09-05 Hangzhou Dac Biotech Co., Ltd Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules
FR3010839B1 (fr) * 2013-09-17 2017-04-21 Schneider Electric Ind Sas Dispositif de raccordement electrique d'au moins un conducteur dans une borne appartenant a un appareil electrique
ES2950384T3 (es) 2014-02-28 2023-10-09 Boehringer Ingelheim Int Uso médico de un inhibidor de DPP-4
ES2960619T3 (es) 2014-02-28 2024-03-05 Hangzhou Dac Biotech Co Ltd Enlazadores cargados y sus usos para la conjugación
AU2015242213A1 (en) 2015-07-12 2018-03-08 Hangzhou Dac Biotech Co., Ltd Bridge linkers for conjugation of cell-binding molecules
US9839687B2 (en) 2015-07-15 2017-12-12 Suzhou M-Conj Biotech Co., Ltd. Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
EP4233840A3 (en) 2016-06-10 2023-10-18 Boehringer Ingelheim International GmbH Combinations of linagliptin and metformin
CN110099682B (zh) 2016-11-14 2023-03-31 杭州多禧生物科技有限公司 偶联连接体，含有此连接体的细胞结合分子-药物偶联物及其制备和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2017724C1 (ru) * 1990-07-12 1994-08-15 Дзе Юниверсити оф Канзас Способ получения производных таксола
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
FR2678930B1 (fr) * 1991-07-10 1995-01-13 Rhone Poulenc Rorer Sa Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.
RU2059631C1 (ru) * 1991-11-29 1996-05-10 Дзе Юниверсити оф Канзас Производные таксола и фармацевтическая композиция, обладающая противоопухолевой активностью
JPH07505887A (ja) * 1992-04-17 1995-06-29 アボツト・ラボラトリーズ タキソール誘導体
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
IL107950A (en) * 1992-12-15 2001-04-30 Upjohn Co b 7, b 8 - Matano - Taxols, their preparation and pharmaceutical preparations against malignant tumors containing them

Also Published As

Publication number Publication date
DE69630145T2 (de) 2004-07-15
TNSN96169A1 (fr) 2005-03-15
TW371659B (en) 1999-10-11
ATE250593T1 (de) 2003-10-15
AU712597B2 (en) 1999-11-11
HK1017895A1 (en) 1999-12-03
JP3953106B2 (ja) 2007-08-08
RO116194B1 (ro) 2000-11-30
CA2238884A1 (fr) 1997-07-03
UA48205C2 (uk) 2002-08-15
IN186768B (es) 2001-11-03
PL327405A1 (en) 1998-12-07
KR100500351B1 (ko) 2005-12-21
KR19990076680A (ko) 1999-10-15
CN1205697A (zh) 1999-01-20
EA001533B1 (ru) 2001-04-23
NO317358B1 (no) 2004-10-18
PL189311B1 (pl) 2005-07-29
IN188680B (es) 2002-10-26
US5728849A (en) 1998-03-17
IL124994A0 (en) 1999-01-26
EP0876362B1 (fr) 2003-09-24
CO4520184A1 (es) 1997-10-15
HUP9904046A3 (en) 2001-08-28
FR2742751A1 (fr) 1997-06-27
NO982580L (no) 1998-06-05
ES2202490T3 (es) 2004-04-01
CZ294972B6 (cs) 2005-04-13
BG102569A (en) 1999-04-30
AR005197A1 (es) 1999-04-14
FR2742751B1 (fr) 1998-01-30
CN1103766C (zh) 2003-03-26
EA199800588A1 (ru) 1998-12-24
CZ196198A3 (cs) 1998-09-16
OA10700A (fr) 2002-11-27
JP2000502671A (ja) 2000-03-07
WO1997023473A1 (fr) 1997-07-03
IN188470B (es) 2002-09-28
HUP9904046A1 (hu) 2001-04-28
DE69630145D1 (de) 2003-10-30
IN188469B (es) 2002-09-28
SK85398A3 (en) 1998-11-04
CA2238884C (fr) 2007-02-06
PT876362E (pt) 2004-02-27
NO982580D0 (no) 1998-06-05
HU225032B1 (en) 2006-05-29
DK0876362T3 (da) 2004-02-02
MX9804688A (es) 1998-10-31
ZA9610737B (en) 1997-06-27
PE25198A1 (es) 1998-05-10
BG63204B1 (bg) 2001-06-29
EP0876362A1 (fr) 1998-11-11
AU1180997A (en) 1997-07-17
MY113934A (en) 2002-06-29
TR199801179T2 (xx) 1998-10-21
SK282835B6 (sk) 2002-12-03
NZ324337A (en) 2000-03-27
BR9612135A (pt) 1999-07-13
MA26412A1 (fr) 2004-12-20
IL124994A (en) 2000-12-06
DZ2149A1 (fr) 2002-10-23

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Legal Events

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ABAN Application deemed to be withdrawn (no publication fee paid)

Effective date: 20090526