MX9301986A - Derivados de perhidroisoindol, procedimiento para su preparacion y composiciones farmaceuticas que los contienen. - Google Patents

Derivados de perhidroisoindol, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.

Info

Publication number
MX9301986A
MX9301986A MX9301986A MX9301986A MX9301986A MX 9301986 A MX9301986 A MX 9301986A MX 9301986 A MX9301986 A MX 9301986A MX 9301986 A MX9301986 A MX 9301986A MX 9301986 A MX9301986 A MX 9301986A
Authority
MX
Mexico
Prior art keywords
derivatives
perhydroisoindol
procedure
contain
preparation
Prior art date
Application number
MX9301986A
Other languages
English (en)
Inventor
Jean-Francois Peyronel
Michel Tabart
Daniel Achard
Serge Grisoni
Jean Luc Malleron
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of MX9301986A publication Critical patent/MX9301986A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se describen nuevos derivados de perhidroisoindol de la fórmula general (I), en la cual, los radicales R son radicales fenilo que pueden estar sustituidos por un átomo de halógeno o un radical metilo en la posición 2 o 3, R1 es un fenilo eventualmente sustituido, ciclohexadienilo, naftilo, indenilo o heterociclilo.
MX9301986A 1992-04-10 1993-04-06 Derivados de perhidroisoindol, procedimiento para su preparacion y composiciones farmaceuticas que los contienen. MX9301986A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR929204390A FR2689888B1 (fr) 1992-04-10 1992-04-10 Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
MX9301986A true MX9301986A (es) 1994-05-31

Family

ID=9428707

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9301986A MX9301986A (es) 1992-04-10 1993-04-06 Derivados de perhidroisoindol, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.

Country Status (24)

Country Link
US (1) US5484804A (es)
EP (1) EP0635003B1 (es)
JP (1) JP3205557B2 (es)
KR (1) KR950700880A (es)
AT (1) ATE167472T1 (es)
AU (1) AU667214B2 (es)
CA (1) CA2133840A1 (es)
CZ (1) CZ284213B6 (es)
DE (1) DE69319235T2 (es)
DK (1) DK0635003T3 (es)
ES (1) ES2118232T3 (es)
FI (1) FI105023B (es)
FR (1) FR2689888B1 (es)
HU (1) HUT71354A (es)
IL (1) IL105255A (es)
MX (1) MX9301986A (es)
NO (1) NO300417B1 (es)
NZ (1) NZ251730A (es)
PL (1) PL172754B1 (es)
RU (1) RU2127260C1 (es)
SK (1) SK279032B6 (es)
TW (1) TW234119B (es)
WO (1) WO1993021155A1 (es)
ZA (1) ZA932527B (es)

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FR2700472B1 (fr) 1993-01-19 1995-02-17 Rhone Poulenc Rorer Sa Association synergisante ayant un effet antagoniste des récepteurs NK1 et NK2.
FR2703679B1 (fr) * 1993-04-05 1995-06-23 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
TW365603B (en) * 1993-07-30 1999-08-01 Rhone Poulenc Rorer Sa Novel perhydroisoindole derivatives, their preparation and pharmaceutical compositions which contain them
FR2710913B1 (fr) * 1993-10-07 1995-11-24 Rhone Poulenc Rorer Sa Nouveaux dérivés de perhydroisoindole, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2709752B1 (fr) * 1993-07-30 1995-10-06 Rhone Poulenc Rorer Sa Nouveaux dérivés de perhydroisoindole, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2710842B1 (fr) * 1993-10-07 1995-11-24 Rhone Poulenc Rorer Sa Nouvelle application thérapeutique de dérivés de perhydroisoindole.
FR2725900B1 (fr) * 1994-10-21 1997-07-18 Sanofi Sa Utilisation d'antagonistes des recepteurs nk1 pour la preparation de medicaments a action cardioregulatrice
FR2727411B1 (fr) * 1994-11-30 1997-01-03 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent
US5789433A (en) * 1995-01-17 1998-08-04 Quadra Logic Technologies, Inc. Green porphyrins as immunomodulators
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DE19636150A1 (de) * 1996-09-06 1998-03-12 Asta Medica Ag N-substituierte Indol-3-glyoxylamide mit antiasthmatischer, antiallergischer und immunsuppressiver/immunmodulierender Wirkung
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Family Cites Families (5)

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Publication number Priority date Publication date Assignee Title
FR514273A (fr) * 1920-04-23 1921-03-07 Georges Loutz Bougie d'allumage électrique pour moteurs à explosions
US4042707A (en) * 1976-02-19 1977-08-16 E. I. Du Pont De Nemours And Company 3α-Arylhydroisoindoles
FR2654725B1 (fr) * 1989-11-23 1992-02-14 Rhone Poulenc Sante Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2676442B1 (fr) * 1991-05-17 1993-08-06 Rhone Poulenc Rorer Sa Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2689889B1 (fr) * 1992-04-10 1994-06-10 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, et leur preparation.

Also Published As

Publication number Publication date
FI944729A0 (fi) 1994-10-07
DE69319235T2 (de) 1999-01-07
AU667214B2 (en) 1996-03-14
US5484804A (en) 1996-01-16
FI105023B (fi) 2000-05-31
NO943692L (no) 1994-10-03
RU2127260C1 (ru) 1999-03-10
TW234119B (es) 1994-11-11
SK122094A3 (en) 1995-05-10
NZ251730A (en) 1995-08-28
ES2118232T3 (es) 1998-09-16
HU9402911D0 (en) 1995-01-30
HUT71354A (en) 1995-11-28
DK0635003T3 (da) 1999-02-15
WO1993021155A1 (fr) 1993-10-28
CZ284213B6 (cs) 1998-09-16
CZ248294A3 (en) 1995-11-15
SK279032B6 (sk) 1998-05-06
FR2689888A1 (fr) 1993-10-15
IL105255A0 (en) 1993-08-18
NO300417B1 (no) 1997-05-26
FR2689888B1 (fr) 1994-06-10
EP0635003B1 (fr) 1998-06-17
NO943692D0 (no) 1994-10-03
ATE167472T1 (de) 1998-07-15
KR950700880A (ko) 1995-02-20
JPH07505410A (ja) 1995-06-15
DE69319235D1 (de) 1998-07-23
FI944729A (fi) 1994-10-07
AU3956593A (en) 1993-11-18
EP0635003A1 (fr) 1995-01-25
PL172754B1 (pl) 1997-11-28
RU94045855A (ru) 1996-09-10
IL105255A (en) 1997-02-18
JP3205557B2 (ja) 2001-09-04
CA2133840A1 (fr) 1993-10-28
ZA932527B (en) 1993-11-08

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