ATE167472T1 - Perhydroisoindole derivate als substanz p antagonisten - Google Patents

Perhydroisoindole derivate als substanz p antagonisten

Info

Publication number
ATE167472T1
ATE167472T1 AT93909005T AT93909005T ATE167472T1 AT E167472 T1 ATE167472 T1 AT E167472T1 AT 93909005 T AT93909005 T AT 93909005T AT 93909005 T AT93909005 T AT 93909005T AT E167472 T1 ATE167472 T1 AT E167472T1
Authority
AT
Austria
Prior art keywords
optionally
pct
date oct
optionally substituted
sec
Prior art date
Application number
AT93909005T
Other languages
English (en)
Inventor
Daniel Achard
Serge Grisoni
Jean-Luc Malleron
Jean-Francois Peyronel
Michel Tabart
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Application granted granted Critical
Publication of ATE167472T1 publication Critical patent/ATE167472T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT93909005T 1992-04-10 1993-04-08 Perhydroisoindole derivate als substanz p antagonisten ATE167472T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR929204390A FR2689888B1 (fr) 1992-04-10 1992-04-10 Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
ATE167472T1 true ATE167472T1 (de) 1998-07-15

Family

ID=9428707

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93909005T ATE167472T1 (de) 1992-04-10 1993-04-08 Perhydroisoindole derivate als substanz p antagonisten

Country Status (24)

Country Link
US (1) US5484804A (de)
EP (1) EP0635003B1 (de)
JP (1) JP3205557B2 (de)
KR (1) KR950700880A (de)
AT (1) ATE167472T1 (de)
AU (1) AU667214B2 (de)
CA (1) CA2133840A1 (de)
CZ (1) CZ284213B6 (de)
DE (1) DE69319235T2 (de)
DK (1) DK0635003T3 (de)
ES (1) ES2118232T3 (de)
FI (1) FI105023B (de)
FR (1) FR2689888B1 (de)
HU (1) HUT71354A (de)
IL (1) IL105255A (de)
MX (1) MX9301986A (de)
NO (1) NO300417B1 (de)
NZ (1) NZ251730A (de)
PL (1) PL172754B1 (de)
RU (1) RU2127260C1 (de)
SK (1) SK279032B6 (de)
TW (1) TW234119B (de)
WO (1) WO1993021155A1 (de)
ZA (1) ZA932527B (de)

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FR2700472B1 (fr) 1993-01-19 1995-02-17 Rhone Poulenc Rorer Sa Association synergisante ayant un effet antagoniste des récepteurs NK1 et NK2.
FR2703679B1 (fr) * 1993-04-05 1995-06-23 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2710913B1 (fr) * 1993-10-07 1995-11-24 Rhone Poulenc Rorer Sa Nouveaux dérivés de perhydroisoindole, leur préparation et les compositions pharmaceutiques qui les contiennent.
TW365603B (en) * 1993-07-30 1999-08-01 Rhone Poulenc Rorer Sa Novel perhydroisoindole derivatives, their preparation and pharmaceutical compositions which contain them
FR2709752B1 (fr) * 1993-07-30 1995-10-06 Rhone Poulenc Rorer Sa Nouveaux dérivés de perhydroisoindole, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2710842B1 (fr) * 1993-10-07 1995-11-24 Rhone Poulenc Rorer Sa Nouvelle application thérapeutique de dérivés de perhydroisoindole.
FR2725900B1 (fr) * 1994-10-21 1997-07-18 Sanofi Sa Utilisation d'antagonistes des recepteurs nk1 pour la preparation de medicaments a action cardioregulatrice
FR2727411B1 (fr) * 1994-11-30 1997-01-03 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent
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DE19636150A1 (de) * 1996-09-06 1998-03-12 Asta Medica Ag N-substituierte Indol-3-glyoxylamide mit antiasthmatischer, antiallergischer und immunsuppressiver/immunmodulierender Wirkung
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FR514273A (fr) * 1920-04-23 1921-03-07 Georges Loutz Bougie d'allumage électrique pour moteurs à explosions
US4042707A (en) * 1976-02-19 1977-08-16 E. I. Du Pont De Nemours And Company 3α-Arylhydroisoindoles
FR2654725B1 (fr) * 1989-11-23 1992-02-14 Rhone Poulenc Sante Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2676442B1 (fr) * 1991-05-17 1993-08-06 Rhone Poulenc Rorer Sa Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2689889B1 (fr) * 1992-04-10 1994-06-10 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, et leur preparation.

Also Published As

Publication number Publication date
JP3205557B2 (ja) 2001-09-04
NZ251730A (en) 1995-08-28
FR2689888A1 (fr) 1993-10-15
DE69319235T2 (de) 1999-01-07
AU3956593A (en) 1993-11-18
FR2689888B1 (fr) 1994-06-10
FI105023B (fi) 2000-05-31
KR950700880A (ko) 1995-02-20
HUT71354A (en) 1995-11-28
NO300417B1 (no) 1997-05-26
SK279032B6 (sk) 1998-05-06
DK0635003T3 (da) 1999-02-15
SK122094A3 (en) 1995-05-10
US5484804A (en) 1996-01-16
ZA932527B (en) 1993-11-08
RU94045855A (ru) 1996-09-10
DE69319235D1 (de) 1998-07-23
IL105255A (en) 1997-02-18
NO943692L (no) 1994-10-03
EP0635003A1 (de) 1995-01-25
TW234119B (de) 1994-11-11
FI944729L (fi) 1994-10-07
AU667214B2 (en) 1996-03-14
CZ284213B6 (cs) 1998-09-16
JPH07505410A (ja) 1995-06-15
CZ248294A3 (en) 1995-11-15
HU9402911D0 (en) 1995-01-30
FI944729A0 (fi) 1994-10-07
ES2118232T3 (es) 1998-09-16
NO943692D0 (no) 1994-10-03
WO1993021155A1 (fr) 1993-10-28
EP0635003B1 (de) 1998-06-17
IL105255A0 (en) 1993-08-18
MX9301986A (es) 1994-05-31
CA2133840A1 (fr) 1993-10-28
PL172754B1 (pl) 1997-11-28
RU2127260C1 (ru) 1999-03-10

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