AP694A - Nitro-benzamides useful as anti-arrhythmic agents. - Google Patents

Nitro-benzamides useful as anti-arrhythmic agents. Download PDF

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Publication number
AP694A
AP694A APAP/P/1997/000965A AP9700965A AP694A AP 694 A AP694 A AP 694A AP 9700965 A AP9700965 A AP 9700965A AP 694 A AP694 A AP 694A
Authority
AP
ARIPO
Prior art keywords
formula
compound
group
pharmaceutically acceptable
salt
Prior art date
Application number
APAP/P/1997/000965A
Other languages
English (en)
Other versions
AP9700965A0 (en
Inventor
Guy Marguerite Marie Gerard Nadler
Michael Jean Roger Martin
Original Assignee
Smithkline Beecham Laboratoires Pharmaceutiques
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Laboratoires Pharmaceutiques filed Critical Smithkline Beecham Laboratoires Pharmaceutiques
Publication of AP9700965A0 publication Critical patent/AP9700965A0/xx
Application granted granted Critical
Publication of AP694A publication Critical patent/AP694A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/78—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
APAP/P/1997/000965A 1994-10-26 1995-10-24 Nitro-benzamides useful as anti-arrhythmic agents. AP694A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9412806A FR2726267B1 (fr) 1994-10-26 1994-10-26 Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer
PCT/EP1995/004203 WO1996013479A1 (en) 1994-10-26 1995-10-24 Nitro-benzamides useful as anti-arrhythmic agents

Publications (2)

Publication Number Publication Date
AP9700965A0 AP9700965A0 (en) 1997-04-30
AP694A true AP694A (en) 1998-11-18

Family

ID=9468229

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1997/000965A AP694A (en) 1994-10-26 1995-10-24 Nitro-benzamides useful as anti-arrhythmic agents.

Country Status (36)

Country Link
US (3) US5977179A (uk)
EP (1) EP0788474B1 (uk)
JP (1) JPH10508013A (uk)
KR (1) KR100369958B1 (uk)
CN (1) CN1071740C (uk)
AP (1) AP694A (uk)
AT (1) ATE192428T1 (uk)
AU (1) AU697357B2 (uk)
BG (1) BG63367B1 (uk)
BR (1) BR9509432A (uk)
CA (1) CA2203814A1 (uk)
CZ (1) CZ290326B6 (uk)
DE (1) DE69516708T2 (uk)
DK (1) DK0788474T3 (uk)
DZ (1) DZ1937A1 (uk)
ES (1) ES2145306T3 (uk)
FI (1) FI971755A (uk)
FR (1) FR2726267B1 (uk)
GR (1) GR3033748T3 (uk)
HK (1) HK1002764A1 (uk)
HU (1) HU222889B1 (uk)
ID (1) ID18094A (uk)
IL (1) IL115732A (uk)
MA (1) MA23706A1 (uk)
NO (1) NO971955L (uk)
NZ (1) NZ295368A (uk)
OA (1) OA10478A (uk)
PL (1) PL181936B1 (uk)
PT (1) PT788474E (uk)
RO (1) RO117174B1 (uk)
RU (1) RU2159227C2 (uk)
SK (1) SK281743B6 (uk)
TR (1) TR199501320A2 (uk)
UA (1) UA50722C2 (uk)
WO (1) WO1996013479A1 (uk)
ZA (1) ZA958984B (uk)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2726267B1 (fr) 1994-10-26 1998-01-02 Smithkline Beecham Lab Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer
GB9706376D0 (en) * 1997-03-27 1997-05-14 Smithkline Beecham Plc Novel pharmaceutical
GB9923933D0 (en) * 1999-10-08 1999-12-08 Smithkline Beecham Lab Novel pharmaceutical
GB9923934D0 (en) * 1999-10-08 1999-12-08 Smithkline Beecham Plc Novel pharmaceutical
IL150650A0 (en) 2000-01-20 2003-02-12 Eisai Co Ltd Piperidine derivatives and pharmaceutical compositions containing the same
KR101403264B1 (ko) * 2002-10-11 2014-06-02 백스터 인터내셔널 인코포레이티드 할로겐화된 휘발성 마취제의 정맥내 투여에 의한 심장보호 및 신경보호방법
KR20050114641A (ko) 2003-03-07 2005-12-06 아스텔라스세이야쿠 가부시키가이샤 2,6-이치환된 스티릴을 갖는 질소 함유 헤테로환 유도체
RU2700263C1 (ru) * 2019-05-16 2019-09-16 федеральное государственное автономное образовательное учреждение высшего образования «Национальный исследовательский Томский политехнический университет» Средство, обладающее антиаритмическим действием

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208252A (en) * 1992-07-24 1993-05-04 Ortho Pharmaceutical Corporation Aminoethylthiophene derivatives

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE242344C (uk)
US3139456A (en) * 1960-07-27 1964-06-30 Searle & Co Nu-(substituted phenoxyalkyl)-aralkylamines
DE3242344A1 (de) * 1982-11-16 1984-05-17 Dr. Karl Thomae Gmbh, 7950 Biberach Neue alkylendiaminoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
EG18188A (en) * 1986-05-01 1992-09-30 Pfizer Ltd Process for preparation anti-arhythmia agents
GB8706662D0 (en) * 1987-03-20 1987-04-23 Pfizer Ltd Anti-arrhythmia agents
CZ283038B6 (cs) * 1991-01-11 1997-12-17 Laboratoires Glaxo Sa Akridinové deriváty, způsob výroby a farmaceutické prostředky s jejich obsahem
DE4422517A1 (de) * 1994-06-28 1996-01-04 Dresden Arzneimittel Neue (2-(3,4-Dimethoxy-phenyl)-ethyl)-(2-phenoxy-ethyl)-amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
CA2196672A1 (en) * 1994-08-04 1996-02-15 You Sup Chung Amine derivatives, processes for producing same, and use thereof as antiarrhythmic drugs
FR2726267B1 (fr) 1994-10-26 1998-01-02 Smithkline Beecham Lab Nouveaux agents anti-arythmiques, compositions pharmaceutiques les contenant, et procede pour les preparer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208252A (en) * 1992-07-24 1993-05-04 Ortho Pharmaceutical Corporation Aminoethylthiophene derivatives

Also Published As

Publication number Publication date
NO971955L (no) 1997-06-25
SK281743B6 (sk) 2001-07-10
AU3869995A (en) 1996-05-23
UA50722C2 (uk) 2002-11-15
US20010025054A1 (en) 2001-09-27
FI971755A0 (fi) 1997-04-24
ZA958984B (en) 1997-04-24
RU2159227C2 (ru) 2000-11-20
ES2145306T3 (es) 2000-07-01
US6570037B2 (en) 2003-05-27
CZ290326B6 (cs) 2002-07-17
HUT77004A (hu) 1998-03-02
EP0788474A1 (en) 1997-08-13
PL319904A1 (en) 1997-09-01
DE69516708T2 (de) 2000-09-28
MX9703112A (es) 1997-07-31
FI971755A (fi) 1997-06-23
HK1002764A1 (en) 1998-09-18
DK0788474T3 (da) 2000-09-11
IL115732A0 (en) 1996-05-14
HU222889B1 (hu) 2003-12-29
US20020107243A1 (en) 2002-08-08
WO1996013479A1 (en) 1996-05-09
ID18094A (id) 1998-02-26
EP0788474B1 (en) 2000-05-03
BG63367B1 (bg) 2001-11-30
US5977179A (en) 1999-11-02
TR199501320A2 (tr) 1996-06-21
IL115732A (en) 2000-08-31
KR100369958B1 (ko) 2003-04-08
GR3033748T3 (en) 2000-10-31
SK50597A3 (en) 1997-11-05
JPH10508013A (ja) 1998-08-04
RO117174B1 (ro) 2001-11-30
CN1071740C (zh) 2001-09-26
CN1170402A (zh) 1998-01-14
CZ125297A3 (en) 1997-10-15
ATE192428T1 (de) 2000-05-15
CA2203814A1 (en) 1996-05-09
FR2726267B1 (fr) 1998-01-02
PL181936B1 (pl) 2001-10-31
FR2726267A1 (fr) 1996-05-03
DZ1937A1 (fr) 2002-02-17
OA10478A (en) 2002-04-09
DE69516708D1 (de) 2000-06-08
BG101501A (en) 1998-01-30
AP9700965A0 (en) 1997-04-30
AU697357B2 (en) 1998-10-01
MA23706A1 (fr) 1996-07-01
NZ295368A (en) 1998-12-23
BR9509432A (pt) 1998-01-06
PT788474E (pt) 2000-08-31
NO971955D0 (no) 1997-04-25

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