AP548A - Controlled-release dosage forms of azithromycin. - Google Patents

Controlled-release dosage forms of azithromycin. Download PDF

Info

Publication number
AP548A
AP548A APAP/P/1995/000735A AP9500735A AP548A AP 548 A AP548 A AP 548A AP 9500735 A AP9500735 A AP 9500735A AP 548 A AP548 A AP 548A
Authority
AP
ARIPO
Prior art keywords
azithromycin
dosage form
membrane
tablet
coating
Prior art date
Application number
APAP/P/1995/000735A
Other languages
English (en)
Other versions
AP9500735A0 (en
Inventor
William John Curatolo
Hylar L Friedman
Richard W Korsmeyer
Mott Steven R Le
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22900590&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP548(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of AP9500735A0 publication Critical patent/AP9500735A0/xx
Application granted granted Critical
Publication of AP548A publication Critical patent/AP548A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
APAP/P/1995/000735A 1994-05-06 1995-04-27 Controlled-release dosage forms of azithromycin. AP548A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23909494A 1994-05-06 1994-05-06

Publications (2)

Publication Number Publication Date
AP9500735A0 AP9500735A0 (en) 1995-04-30
AP548A true AP548A (en) 1996-10-30

Family

ID=22900590

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1995/000735A AP548A (en) 1994-05-06 1995-04-27 Controlled-release dosage forms of azithromycin.

Country Status (42)

Country Link
US (2) US6068859A (fr)
EP (1) EP0758244B2 (fr)
JP (1) JP2977907B2 (fr)
KR (1) KR100232297B1 (fr)
CN (1) CN1096862C (fr)
AP (1) AP548A (fr)
AT (1) ATE209497T1 (fr)
AU (1) AU680356B2 (fr)
BG (1) BG63152B1 (fr)
BR (1) BR9501929A (fr)
CA (1) CA2189658C (fr)
CO (1) CO4290346A1 (fr)
CZ (1) CZ292360B6 (fr)
DE (1) DE69524214T3 (fr)
DK (1) DK0758244T4 (fr)
DZ (1) DZ1880A1 (fr)
ES (1) ES2163504T5 (fr)
FI (1) FI964452A0 (fr)
HR (1) HRP950277B1 (fr)
HU (1) HUT77530A (fr)
IL (3) IL131308A (fr)
IS (1) IS4282A (fr)
LV (1) LV11729B (fr)
MA (1) MA23537A1 (fr)
MX (1) MX9605419A (fr)
MY (1) MY113059A (fr)
NO (1) NO315453B1 (fr)
NZ (1) NZ283160A (fr)
OA (1) OA10320A (fr)
PE (1) PE4796A1 (fr)
PL (1) PL179910B1 (fr)
PT (1) PT758244E (fr)
RO (1) RO114740B1 (fr)
RU (1) RU2130311C1 (fr)
SI (1) SI9520049A (fr)
SK (1) SK282854B6 (fr)
TN (1) TNSN95051A1 (fr)
TW (1) TW420616B (fr)
UA (1) UA41995C2 (fr)
UY (1) UY23958A1 (fr)
WO (1) WO1995030422A1 (fr)
ZA (1) ZA953627B (fr)

Families Citing this family (199)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5914132A (en) * 1993-02-26 1999-06-22 The Procter & Gamble Company Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery
US5605889A (en) 1994-04-29 1997-02-25 Pfizer Inc. Method of administering azithromycin
RO114740B1 (ro) * 1994-05-06 1999-07-30 Pfizer Compozitie cu eliberare controlata, procedeu de obtinere a acesteia si metoda de tratament
US6262115B1 (en) * 1995-05-22 2001-07-17 Alza Coporation Method for the management of incontinence
US5912268A (en) * 1995-05-22 1999-06-15 Alza Corporation Dosage form and method for treating incontinence
US6548084B2 (en) 1995-07-20 2003-04-15 Smithkline Beecham Plc Controlled release compositions
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6645988B2 (en) * 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
HRP970493A2 (en) * 1996-09-23 1998-08-31 Wienman E. Phlips Oral delayed immediate release medical formulation and method for preparing the same
CA2271569C (fr) * 1996-11-15 2003-01-28 Gary Lee Manring Forme galenique pharmaceutique comportant des revetements enteriques polymeres multiples pour administration dans le colon
US6010718A (en) * 1997-04-11 2000-01-04 Abbott Laboratories Extended release formulations of erythromycin derivatives
US6551616B1 (en) 1997-04-11 2003-04-22 Abbott Laboratories Extended release formulations of erythromycin derivatives
US20040028735A1 (en) * 1997-11-14 2004-02-12 Unchalee Kositprapa Pharmaceutical formulation
US6306642B1 (en) * 1997-11-24 2001-10-23 Quidel Corporation Enzyme substrate delivery and product registration in one step enzyme immunoassays
PT1421939E (pt) * 1998-03-26 2010-07-12 Astellas Pharma Inc Preparaã†o da libertaã†o sustentada de um composto de macrëlido como tracolimus
EP1083879B1 (fr) * 1998-06-03 2004-09-29 Alza Corporation Dispositifs servant a maintenir un effet therapeutique prolonge
DE19850445A1 (de) * 1998-11-02 2000-05-04 Falk Pharma Gmbh Arzneimittel zur topischen Behandlung entzündlicher Darmerkrankungen
EP1027887B1 (fr) * 1999-02-10 2008-08-13 Pfizer Products Inc. Dispositif pour la libération du principe actif contrôlée par la matrice
US6706283B1 (en) * 1999-02-10 2004-03-16 Pfizer Inc Controlled release by extrusion of solid amorphous dispersions of drugs
US6878386B1 (en) * 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
EP1207852A4 (fr) * 1999-09-02 2009-11-11 Nostrum Pharmaceuticals Inc Dosage oral a liberation regulee destine a l'administration orale
JP2003518487A (ja) 1999-12-23 2003-06-10 ファイザー・プロダクツ・インク ヒドロゲル駆動型積層薬物製剤
YU35302A (sh) * 1999-12-23 2005-03-15 Pfizer Products Inc. Dozirani oblik leka sa inicijalnim hidrogelom
IL141438A0 (en) * 2000-02-23 2002-03-10 Pfizer Prod Inc Method of increasing the bioavailability and tissue penetration of azithromycin
US6991807B2 (en) * 2000-02-24 2006-01-31 Advancis Pharmaceutical, Corp. Antibiotic composition
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US20050175959A1 (en) * 2000-03-14 2005-08-11 Coll Partners Ltd. System for the controlled delivery of an active material to a dental site
IL135061A0 (en) * 2000-03-14 2001-05-20 Ahron Jodaikin Strategic targeted fluoridation and chemical treatment of teeth
US6569152B2 (en) 2000-03-21 2003-05-27 Farrington Pharmaceuticals, Llc Sustained release delivery systems for solutes
FR2811571B1 (fr) * 2000-07-11 2002-10-11 Flamel Tech Sa Composition pharmaceutique orale, permettant la liberation controlee et l'absorption prolongee d'un principe actif
US20030086972A1 (en) * 2000-08-09 2003-05-08 Appel Leah E. Hydrogel-driven drug dosage form
MXPA03001771A (es) 2000-08-30 2003-06-04 Pfizer Prod Inc Formulaciones de liberacion sostenida para secretagogos de hormona del crecimiento.
US6541014B2 (en) * 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
GB0025208D0 (en) * 2000-10-13 2000-11-29 Euro Celtique Sa Delayed release pharmaceutical formulations
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US20020197314A1 (en) 2001-02-23 2002-12-26 Rudnic Edward M. Anti-fungal composition
FR2821745B1 (fr) * 2001-03-09 2004-07-02 Ethypharm Lab Prod Ethiques Granules et granules enrobes au gout masque
AU2002248792B2 (en) * 2001-04-18 2006-09-21 Nostrum Pharmaceuticals Inc. A novel coating for a sustained release pharmaceutical composition
HRP20010301A2 (en) * 2001-04-27 2001-12-31 Pliva D D New therapeutic indication for azithromycin in the treatment of non-infective inflammatory diseases
EP1671979B1 (fr) 2001-05-22 2008-08-13 Pfizer Products Inc. Nouvelle forme cristalline de l'azithromycine
US20080305173A1 (en) * 2001-07-31 2008-12-11 Beuford Arlie Bogue Amorphous drug beads
EA200400214A1 (ru) * 2001-08-21 2004-06-24 Пфайзер Продактс Инк. Азитромицин в виде разовой дозы
WO2003017981A1 (fr) * 2001-08-29 2003-03-06 Ranbaxy Laboratories Limited Formulation a liberation controlee de clarithromycine ou de tinidazol
FR2830447B1 (fr) * 2001-10-09 2004-04-16 Flamel Tech Sa Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques
US8101209B2 (en) * 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
EP1541134A3 (fr) * 2001-10-18 2007-06-06 Teva Pharmaceutical Industries Limited Compositions stabilisées de azithromycin
US20030091630A1 (en) * 2001-10-25 2003-05-15 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral dosage form using in vitro disintegration test data
TWI312285B (en) 2001-10-25 2009-07-21 Depomed Inc Methods of treatment using a gastric retained gabapentin dosage
US20030152622A1 (en) * 2001-10-25 2003-08-14 Jenny Louie-Helm Formulation of an erodible, gastric retentive oral diuretic
US7612112B2 (en) 2001-10-25 2009-11-03 Depomed, Inc. Methods of treatment using a gastric retained gabapentin dosage
US20060159743A1 (en) * 2001-10-25 2006-07-20 Depomed, Inc. Methods of treating non-nociceptive pain states with gastric retentive gabapentin
WO2003053428A1 (fr) * 2001-12-20 2003-07-03 Pharmacia Corporation Forme posologique de liberation a controlee possedant des proprietes ameliorees de liberation de medicaments
IL161259A0 (en) * 2001-12-21 2004-09-27 Pfizer Prod Inc Methods for wet granulating azithromycin
NZ532707A (en) * 2001-12-21 2006-07-28 Pfizer Prod Inc Directly compressible formulations of azithromycin
KR100540035B1 (ko) * 2002-02-01 2005-12-29 주식회사 태평양 다단계 경구 약물 방출 제어 시스템
NZ534234A (en) * 2002-02-01 2007-05-31 Pfizer Prod Inc Dry granulated formulations of non-dihydrate form of azithromycin
KR100758045B1 (ko) * 2002-02-01 2007-09-11 화이자 프로덕츠 인크. 압력 노즐을 이용하여 균질한 분무 건조된 비결정질 고체약물 분산제를 제조하는 방법
JP4865989B2 (ja) 2002-02-01 2012-02-01 ベンド・リサーチ・インコーポレーテッド 改良された噴霧乾燥装置を使用する均質な噴霧乾燥された固体の非晶質薬物分散物を製造する方法
US6682759B2 (en) * 2002-02-01 2004-01-27 Depomed, Inc. Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs
GB0203296D0 (en) * 2002-02-12 2002-03-27 Glaxo Group Ltd Novel composition
CA2480824A1 (fr) * 2002-04-09 2003-10-16 Flamel Technologies Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee d'amoxicilline
DE60325709D1 (de) 2002-04-09 2009-02-26 Flamel Tech Sa Orale wässrige suspension, mikrokapseln enthaltend, zur kontrollierten freisetzung von wirkstoffen
WO2003105810A1 (fr) * 2002-06-14 2003-12-24 Andrx Corporation Compositions pharmaceutiques pour medicaments ayant une solubilite dependant du ph
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
GB0214013D0 (en) * 2002-06-18 2002-07-31 Euro Celtique Sa Pharmaceutical product
US20040028737A1 (en) * 2002-08-12 2004-02-12 Kopran Research Laboratories Limited Enteric coated stable oral pharmaceutical composition of acid unstable drug and process for preparing the same
US8980870B2 (en) * 2002-09-24 2015-03-17 Boehringer Ingelheim International Gmbh Solid telmisartan pharmaceutical formulations
US20040062778A1 (en) * 2002-09-26 2004-04-01 Adi Shefer Surface dissolution and/or bulk erosion controlled release compositions and devices
MY148805A (en) * 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
EP1558211A2 (fr) * 2002-10-30 2005-08-03 Pharmacia Corporation Comprimes oraux a liberation etendue et procedes de fabrication et d'utilisation associes
US7351430B2 (en) * 2002-11-06 2008-04-01 Uluru Inc. Shape-retentive hydrogel particle aggregates and their uses
US7811605B2 (en) * 2002-11-06 2010-10-12 Uluru Inc. Method of formation of shape-retentive aggregates of gel particles and their uses
US7670627B2 (en) * 2002-12-09 2010-03-02 Salvona Ip Llc pH triggered targeted controlled release systems for the delivery of pharmaceutical active ingredients
US20040114368A1 (en) * 2002-12-13 2004-06-17 Shyu Shing Jy Light device having rotatable or movable view
PL220457B1 (pl) 2002-12-16 2015-10-30 Kissei Pharmaceutical Kapsułka do leczenia dysurii
EP1589951B1 (fr) * 2003-01-03 2017-08-09 Supernus Pharmaceuticals, Inc. Utilisation d'un melange de deux ou de plusieurs materiaux enteriques afin de reguler la liberation de medicaments via une membrane ou une matrice dans des therapies systemiques
FR2850577B1 (fr) * 2003-02-03 2005-04-15 Ethypharm Sa Particules enrobees a gout masque, leur procede de preparation et comprimes orodispersibles contenant lesdites particules
CA2524827A1 (fr) * 2003-05-06 2004-11-25 Nirmal Mulye Formulation a liberation controlee de derives d'erythromycine
US7063862B2 (en) 2003-06-03 2006-06-20 Biokey, Inc. Pharmaceutical composition and method for treating
CA2673334C (fr) * 2003-06-16 2013-11-12 Andrx Pharmaceuticals, Llc Composition orale a liberation prolongee
US20050013835A1 (en) * 2003-07-15 2005-01-20 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
AU2004258949B2 (en) 2003-07-21 2011-02-10 Shionogi, Inc. Antibiotic product, use and formulation thereof
CA2533292C (fr) 2003-07-21 2013-12-31 Advancis Pharmaceutical Corporation Produit antibiotique, utilisation et formulation correspondantes
EP1648418A4 (fr) 2003-07-21 2011-11-16 Middlebrook Pharmaceuticals Inc Produit antibiotique, utilisation et formulation associees
JP2005041838A (ja) * 2003-07-24 2005-02-17 Matsumoto Shika Univ バイオフィルム除去剤
US20050025829A1 (en) * 2003-07-29 2005-02-03 Kim Cherng-Ju Controlled drug release tablets
CL2004001884A1 (es) * 2003-08-04 2005-06-03 Pfizer Prod Inc Procedimiento de secado por pulverizacion para la formacion de dispersiones solidas amorfas de un farmaco y polimeros.
DE10336400A1 (de) 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
DE102004032051A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
CA2535177A1 (fr) 2003-08-11 2005-02-24 Advancis Pharmaceutical Corporation Pastille robuste
EP1653924A4 (fr) * 2003-08-12 2009-09-09 Middlebrook Pharmaceuticals In Antibiotique, utilisation et formulation associees
CA2535780A1 (fr) 2003-08-29 2005-03-17 Advancis Pharmaceuticals Corporation Produit antibiotique, son utilisation et sa formulation
US8460710B2 (en) 2003-09-15 2013-06-11 Shionogi, Inc. Antibiotic product, use and formulation thereof
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
CA2547597A1 (fr) * 2003-12-04 2005-06-16 Pfizer Products Inc. Compositions multiparticulaires a stabilite amelioree
CN1889931A (zh) * 2003-12-04 2007-01-03 辉瑞产品公司 利用挤压器制备优选含泊洛沙姆和甘油酯的多重粒子阿奇霉素组合物的喷雾-冻凝方法
WO2005053652A1 (fr) * 2003-12-04 2005-06-16 Pfizer Products Inc. Compositions medicamenteuses cristallines multiparticulaires contenant un poloxamere et un glyceride
MXPA06005913A (es) * 2003-12-04 2006-06-27 Pfizer Prod Inc Formas de dosificacion de multiparticulas de azitromicina por procedimientos basados en liquidos.
CN1889932A (zh) * 2003-12-04 2007-01-03 辉瑞产品公司 制备药用多颗粒的方法
WO2005053654A1 (fr) * 2003-12-04 2005-06-16 Pfizer Products Inc. Formes posologiques d'azithromycine a liberation controlee
EP1689368B1 (fr) * 2003-12-04 2016-09-28 Bend Research, Inc Procédé d'atomisation/congélation faisant appel à une extrudeuse pour la préparation de compositions médicamenteuses cristallines multiparticulaires
WO2005053639A2 (fr) * 2003-12-04 2005-06-16 Pfizer Products Inc. Formes multiparticulaires a liberation controlee produites avec des optimiseurs de dissolution
US20040224019A1 (en) * 2004-03-03 2004-11-11 Adi Shefer Oral controlled release system for targeted drug delivery into the cell and its nucleus for gene therapy, DNA vaccination, and administration of gene based drugs
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
US20050226927A1 (en) * 2004-04-02 2005-10-13 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties that contain a GABAB receptor agonist
US8007827B2 (en) * 2004-04-02 2011-08-30 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties
US8697031B2 (en) * 2004-06-04 2014-04-15 Case Western Reserve University Dual function polymer micelles
EP1753405A4 (fr) * 2004-06-10 2008-09-17 Glatt Air Tech Inc Preparation pharmaceutique a liberation lente
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
CA2572292A1 (fr) 2004-07-02 2006-02-09 Advancis Pharmaceutical Corporation Comprime pour distribution par impulsion
DE202005022112U1 (de) * 2004-10-08 2014-04-24 Forward Pharma A/S Pharmazeutische Zusammensetzungen mit kontrollierter Freisetzung, umfassend einen Fumarsaureester
US20080199527A1 (en) * 2004-12-21 2008-08-21 Pfizer Inc. Enteric Coated Azithromycin Multiparticulates
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
US10071060B2 (en) * 2005-07-08 2018-09-11 Bioventures, Llc Asymmetrically coated table
US8858993B2 (en) * 2005-07-25 2014-10-14 Metrics, Inc. Coated tablet with zero-order or near zero-order release kinetics
EP1749519A1 (fr) * 2005-08-05 2007-02-07 Schering Aktiengesellschaft Forme galénique à libération prolongée pH-indépendant pour les substances actives avec une solubilité pH-dépendante
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
CA2634830A1 (fr) * 2005-12-27 2007-07-05 Labopharm Inc. Composition de microbilles a base de polymere degradable
US20090176882A1 (en) 2008-12-09 2009-07-09 Depomed, Inc. Gastric retentive gabapentin dosage forms and methods for using same
US20070191271A1 (en) * 2006-02-10 2007-08-16 Dow Pharmaceutical Sciences Method for stabilizing polypeptides lacking methionine
US20070243248A1 (en) * 2006-04-14 2007-10-18 Cherukuri S Rao Rapidly disintegrating solid oral dosage form of liquid dispersions
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
US20070281894A1 (en) * 2006-06-05 2007-12-06 Auspex Pharmaceuticals, Inc. Preparation and utility of substituted erythromycin analogs
US7713549B2 (en) * 2006-06-30 2010-05-11 Board Of Trustees Of The University Of Arkansas Extended release perforated tablet
SA07280459B1 (ar) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
US7910135B2 (en) * 2006-10-13 2011-03-22 Uluru Inc. Hydrogel wound dressing and biomaterials formed in situ and their uses
US20110052688A1 (en) * 2006-11-21 2011-03-03 San-Laung Chow Solid dispersion composition
EP2091519B1 (fr) * 2006-11-30 2015-06-24 Bend Research, Inc Médicament enduit par vaporisation et polymère multiparticulaires sur un noyau pouvant fondre
US11116728B2 (en) 2006-11-30 2021-09-14 Bend Research, Inc. Multiparticulates of spray-coated drug and polymer on a meltable core
CN100441196C (zh) * 2006-12-15 2008-12-10 北京化工大学 一种制备微粉化阿奇霉素的方法
US8895061B2 (en) * 2007-03-02 2014-11-25 Meda Pharmaceuticals Inc. Compositions comprising carisoprodol and methods of use thereof
US20080228268A1 (en) * 2007-03-15 2008-09-18 Uluru, Inc. Method of Formation of Viscous, Shape Conforming Gels and Their Uses as Medical Prosthesis
BRPI0700969A (pt) * 2007-03-22 2008-11-04 Ouro Fino Participacoes E Empr composição para o tratamento de afecções bacterianas e inflamatórias em animais de companhia
US7850453B2 (en) * 2007-08-08 2010-12-14 Coll Partners Ltd. Reshapable device for fixation at a dental site
US8124123B2 (en) * 2007-09-05 2012-02-28 Dow Pharmaceutical Sciences, Inc. Controlled release azithromycin solid dosages forms
AU2008303932A1 (en) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Use of BPP-B as a therapeutic agent
JP2010539059A (ja) 2007-09-11 2010-12-16 モンドバイオテック ラボラトリーズ アクチエンゲゼルシャフト 例えばAIDSまたはアルツハイマーの治療のための治療剤としてのβ−メラノトロピンの使用
AU2008297874A1 (en) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Use of secretin and optionally urodilatin as therapeutic agents
US20100204112A1 (en) 2007-09-11 2010-08-12 Dorian Bevec Use of tyr-w-mif-1 and urocortin 2 as therapeutic agents
AU2008306192A1 (en) 2007-09-11 2009-04-09 Mondobiotech Laboratories Ag Use of leptin (22-56 ) as a therapeutic agent
WO2009033734A2 (fr) 2007-09-11 2009-03-19 Mondobiotech Laboratoires Ag Utilisation d'un peptide comme agent thérapeutique
WO2009039989A1 (fr) 2007-09-11 2009-04-02 Mondobiotech Laboratories Ag Utilisation du peptide gly-arg-gly-asp-asn-pro en tant qu'agent thérapeutique
WO2009033710A1 (fr) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Utilisation du peptide yy, seul ou en combinaison avec un peptide de type glucagon, à usage médical
CA2699006A1 (fr) 2007-09-11 2009-03-19 Mondobiotech Laboratories Ag Utilisation d'un peptide en tant qu'agent therapeutique
EP2249811A1 (fr) 2008-01-25 2010-11-17 Grünenthal GmbH Forme posologique pharmaceutique
DE102008022520A1 (de) * 2008-05-07 2009-11-12 Bayer Animal Health Gmbh Feste Arzneimittelformulierung mit verzögerter Freisetzung
CA2723438C (fr) 2008-05-09 2016-10-11 Gruenenthal Gmbh Procede de preparation d'une formulation de poudre intermediaire et d'une forme galenique solide finale en utilisant une etape de congelation par pulverisation
TWI478712B (zh) 2008-09-30 2015-04-01 Astellas Pharma Inc 釋控性醫藥組成物
EP2198859A1 (fr) * 2008-12-17 2010-06-23 Losan Pharma GmbH Composition pharmaceutique à revêtement par fusion avec libération
BR112012001244A2 (pt) 2009-07-22 2020-12-08 Gruünenthal Gmbh Forma de dosagem resitente à adulteração, seu processo de produção, e embalagem contendo tal forma
WO2011009602A1 (fr) 2009-07-22 2011-01-27 Grünenthal GmbH Forme galénique extrudée à chaud à libération contrôlée
CA2780274C (fr) 2009-11-09 2018-06-26 Spotlight Technology Partners Llc Hydrogels fragmentes
AU2010314992B2 (en) 2009-11-09 2016-09-15 Spotlight Technology Partners Llc Polysaccharide based hydrogels
RU2567049C2 (ru) 2010-03-15 2015-10-27 Ульрих ДИТЦ Применение нитрокарбоновых кислот для лечения, диагностики и профилактики агрессивных форм заживления
WO2011125075A2 (fr) 2010-04-08 2011-10-13 Fdc Limited Nouveau système d'administration à rétention gastrique de macrolides
AR082862A1 (es) 2010-09-02 2013-01-16 Gruenenthal Gmbh Forma de dosificacion resistente a alteracion que comprende un polimero anionico
RU2604676C2 (ru) 2010-09-02 2016-12-10 Грюненталь Гмбх Устойчивая к разрушению лекарственная форма, содержащая неорганическую соль
CA2823628A1 (fr) 2011-01-05 2012-07-12 Hospira, Inc. Sechage par atomisation de la vancomycine
BR112014002022A2 (pt) 2011-07-29 2017-02-21 Gruenenthal Gmbh comprimido resistente à violação proporcionando liberação de fármaco imediata
PT2736497T (pt) 2011-07-29 2017-11-30 Gruenenthal Gmbh Comprimido resistente a adulteração proporcionando libertação imediata de fármaco
DK2741766T3 (en) * 2011-08-08 2016-01-11 Aptalis Pharma Ltd Process for dissolving solid compositions containing digestive enzymes
CA2885680C (fr) * 2011-09-07 2022-10-04 Roland Saur-Brosch Formulation optimale pour la liberation d'un principe actif dans le gros intestin.
US10653631B2 (en) 2011-09-07 2020-05-19 Roland SAUR-BROSCH Optimal colon targeting technology
US20130143867A1 (en) 2011-12-02 2013-06-06 Sychroneuron Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
WO2013088274A1 (fr) 2011-12-14 2013-06-20 Wockhardt Limited Composition d'azithromycine amorphe anhydre dépourvue de dihydrate d'azithromycine
WO2013103801A1 (fr) * 2012-01-04 2013-07-11 Hospira, Inc. Séchage par pulvérisation pharmaceutique
CA2864949A1 (fr) 2012-02-28 2013-09-06 Grunenthal Gmbh Forme pharmaceutique inviolable comprenant un compose pharmacologiquement actif et un polymere anionique
ES2692944T3 (es) 2012-04-18 2018-12-05 Grünenthal GmbH Forma de dosificación farmacéutica resistente a la manipulación y resistente a la descarga rápida de la dosis
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
RU2498805C1 (ru) * 2012-07-23 2013-11-20 Открытое акционерное общество "Биосинтез" Твердая лекарственная форма азитромицина
US20150202161A1 (en) * 2012-08-20 2015-07-23 O-Ray Pharma, Inc. Process for manufacturing drug delivery formulations
CN103860515A (zh) * 2012-12-10 2014-06-18 中国科学院上海药物研究所 阿奇霉素渗透泵控释片及其制备方法
CN104043104B (zh) 2013-03-15 2018-07-10 浙江创新生物有限公司 含盐酸万古霉素的喷雾干粉及其工业化制备方法
JP6041823B2 (ja) 2013-03-16 2016-12-14 ファイザー・インク トファシチニブの経口持続放出剤形
CN104177457A (zh) * 2013-05-23 2014-12-03 长春海悦药业有限公司 一种阿奇霉素药物原料及其制剂和用途
MX371432B (es) 2013-05-29 2020-01-30 Gruenenthal Gmbh Forma de dosificacion resistente al uso indebido que contiene una o mas particulas.
MX2015016254A (es) 2013-05-29 2016-04-20 Gruenenthal Gmbh Forma de dosificacion resistente al uso indebido con perfil de liberacion bimodal.
CN105431144A (zh) 2013-06-05 2016-03-23 思康脑侒股份有限公司 阿坎酸制剂、使用阿坎酸制剂的方法以及包含阿坎酸制剂的组合
US10624862B2 (en) 2013-07-12 2020-04-21 Grünenthal GmbH Tamper-resistant dosage form containing ethylene-vinyl acetate polymer
US9668844B2 (en) 2013-11-06 2017-06-06 Colldent Y.A Ltd Device for fixation at a dental site
CN105934241B (zh) 2013-11-26 2020-06-05 格吕伦塔尔有限公司 通过低温研磨制备粉末状药物组合物
WO2015173195A1 (fr) 2014-05-12 2015-11-19 Grünenthal GmbH Formulation pour capsule à libération immédiate résistant aux manipulations illicites comprenant du tapentadol
AU2015266117A1 (en) 2014-05-26 2016-11-24 Grunenthal Gmbh Multiparticles safeguarded against ethanolic dose-dumping
CN107889459A (zh) 2015-04-24 2018-04-06 格吕伦塔尔有限公司 具有立即释放和对溶剂萃取的抗性的抗篡改剂型
EP3307275B1 (fr) * 2015-06-10 2021-05-26 Piedmont Animal Health Inc. Formulations antibiotiques injectables et utilisation de celles-ci
US10842750B2 (en) 2015-09-10 2020-11-24 Grünenthal GmbH Protecting oral overdose with abuse deterrent immediate release formulations
WO2018190621A1 (fr) * 2017-04-10 2018-10-18 성균관대학교 산학협력단 Préparation à libération prolongée comprenant une couche de rétention gastrique poreuse, et son procédé de préparation
GB201904757D0 (en) * 2019-04-04 2019-05-22 Biorelevant Com Ltd Biorelevant composition
AU2020364192A1 (en) 2019-10-11 2021-07-29 Anatara Lifesciences Limited Gastrointestinal health composition
CN112326838A (zh) * 2020-11-10 2021-02-05 湖北省宏源药业科技股份有限公司 一种改善阿奇霉素胶囊溶出曲线的测定方法
CN113116859B (zh) * 2021-04-12 2022-08-30 海南普利制药股份有限公司 阿奇霉素丸芯包衣制剂
CN113985783B (zh) * 2021-10-29 2022-09-02 中山东菱威力电器有限公司 一种冰激淋料浆有无检测电路

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0307128A2 (fr) * 1987-09-10 1989-03-15 Pfizer Inc. Azitromycine et dérivés comme agents protozoaires
EP0582396A1 (fr) * 1992-07-30 1994-02-09 Pfizer Inc. Compositions pharmaceutiques masquant le mauvais goût à base de composés amers

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2471186A1 (fr) * 1979-12-10 1981-06-19 Roussel Uclaf Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation
US4340582A (en) * 1981-01-15 1982-07-20 Abbott Laboratories Erythromycin base tablets
SI8110592A8 (en) * 1981-03-06 1996-06-30 Pliva Pharm & Chem Works Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof
DK150008C (da) * 1981-11-20 1987-05-25 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat
US4434153A (en) * 1982-03-22 1984-02-28 Alza Corporation Drug delivery system comprising a reservoir containing a plurality of tiny pills
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US4522625A (en) * 1982-09-29 1985-06-11 Alza Corporation Drug dispenser comprising wall formed of semipermeable member and enteric member
PH19293A (en) * 1982-11-15 1986-03-04 Pfizer Epimeric azahomoerythromycin,pharmaceutical composition containing the same and method of use thereof
US4851231A (en) * 1982-12-13 1989-07-25 Alza Corporation System for delivering drug in selected environment of use
US4496322A (en) 1983-05-11 1985-01-29 University Of Toronto Innovations Foundation Benzoin antimicrobial dental varnishes
US4968507A (en) * 1984-06-20 1990-11-06 Merck & Co., Inc. Controlled porosity osmotic pump
DE3524572A1 (de) 1985-07-10 1987-01-15 Thomae Gmbh Dr K Feste arzneimittelformen zur peroralen anwendung enthaltend 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethyliden)-oxy)-(9s)-erythromycin und verfahren zu ihrer herstellung
DE3776187D1 (de) 1986-04-17 1992-03-05 Eltech Systems Corp Elektrode mit platinmetallkatalysator in der oberflaechenschicht und ihre verwendung.
US4792448A (en) * 1987-06-11 1988-12-20 Pfizer Inc. Generic zero order controlled drug delivery system
IT1222309B (it) 1987-07-08 1990-09-05 Menarini Sas Utilizzazione di forme farmaceutiche per uso topico contenenti miocamicina per la terapia delle infezione da germi sensibili alla miocamicina stessa
UA27040C2 (uk) 1987-07-09 2000-02-28 Пфайзер Інк. Кристалічhий дигідрат азитроміциhу та спосіб одержаhhя кристалічhого дигідрату азитроміциhу
IL92966A (en) * 1989-01-12 1995-07-31 Pfizer Hydrogel-operated release devices
WO1990009168A1 (fr) * 1989-02-16 1990-08-23 National Research Development Corporation Dispositif de distribution
AU633617B2 (en) * 1989-07-18 1993-02-04 Alza Corporation Dispenser comprising ionophore
US5084267A (en) 1989-11-17 1992-01-28 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US5198220A (en) 1989-11-17 1993-03-30 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US5173299A (en) 1989-11-17 1992-12-22 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US5230895A (en) 1990-05-01 1993-07-27 Copley Pharmaceutical Inc. Sustained released delivery system for use in the periodontal pocket
WO1991017744A1 (fr) * 1990-05-14 1991-11-28 Jernberg Gary R Procede et implant chirurgical utilisant des agents chimiotherapeutiques
US5114718A (en) 1990-09-20 1992-05-19 The Procter & Gamble Company Sustained release compositions for treating periodontol disease
SE9201930D0 (sv) 1992-06-24 1992-06-24 Astra Ab Gastric antibacterial treatment
EP0670717B1 (fr) 1992-11-30 1998-11-25 Pfizer Inc. Dispositif de distribution a membrane de retenue de liquide
AU7957994A (en) * 1993-10-01 1995-05-01 Procter & Gamble Company, The Use of azithromycin for the treatment of adult periodontitis and topical compositions for this use
US5605889A (en) 1994-04-29 1997-02-25 Pfizer Inc. Method of administering azithromycin
RO114740B1 (ro) 1994-05-06 1999-07-30 Pfizer Compozitie cu eliberare controlata, procedeu de obtinere a acesteia si metoda de tratament
US5747058A (en) * 1995-06-07 1998-05-05 Southern Biosystems, Inc. High viscosity liquid controlled delivery system
US5705190A (en) * 1995-12-19 1998-01-06 Abbott Laboratories Controlled release formulation for poorly soluble basic drugs
US6984403B2 (en) 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0307128A2 (fr) * 1987-09-10 1989-03-15 Pfizer Inc. Azitromycine et dérivés comme agents protozoaires
EP0582396A1 (fr) * 1992-07-30 1994-02-09 Pfizer Inc. Compositions pharmaceutiques masquant le mauvais goût à base de composés amers

Also Published As

Publication number Publication date
DK0758244T4 (da) 2008-06-16
SI9520049A (en) 1997-12-31
US7108865B2 (en) 2006-09-19
ES2163504T5 (es) 2008-05-16
US6068859A (en) 2000-05-30
KR100232297B1 (ko) 1999-12-01
DK0758244T3 (da) 2002-02-11
IS4282A (is) 1995-11-07
RU2130311C1 (ru) 1999-05-20
JP2977907B2 (ja) 1999-11-15
ZA953627B (en) 1996-11-05
PL317106A1 (en) 1997-03-17
UA41995C2 (uk) 2001-10-15
CN1096862C (zh) 2002-12-25
NZ283160A (en) 1998-07-28
CZ292360B6 (cs) 2003-09-17
CN1149831A (zh) 1997-05-14
FI964452A (fi) 1996-11-05
TW420616B (en) 2001-02-01
IL113516A (en) 2001-04-30
ES2163504T3 (es) 2002-02-01
DE69524214T3 (de) 2008-05-15
IL131308A0 (en) 2001-01-28
BG63152B1 (bg) 2001-05-31
RO114740B1 (ro) 1999-07-30
BG100960A (en) 1997-08-29
CA2189658C (fr) 2000-10-31
JPH09505609A (ja) 1997-06-03
MY113059A (en) 2001-11-30
CZ324296A3 (cs) 1998-04-15
PE4796A1 (es) 1996-03-09
SK282854B6 (sk) 2002-12-03
HUT77530A (hu) 1998-05-28
WO1995030422A1 (fr) 1995-11-16
NO964678D0 (no) 1996-11-05
LV11729B (en) 1997-08-20
AU2113195A (en) 1995-11-29
IL113516A0 (en) 1995-07-31
PL179910B1 (pl) 2000-11-30
LV11729A (lv) 1997-04-20
DE69524214T2 (de) 2002-05-23
KR970702727A (ko) 1997-06-10
TNSN95051A1 (fr) 1996-02-06
DZ1880A1 (fr) 2002-02-17
FI964452A0 (fi) 1996-11-05
AU680356B2 (en) 1997-07-24
HRP950277B1 (en) 2002-06-30
PT758244E (pt) 2002-04-29
CA2189658A1 (fr) 1995-11-16
EP0758244B1 (fr) 2001-11-28
IL131308A (en) 2001-07-24
HU9603076D0 (en) 1997-01-28
MX9605419A (es) 1997-12-31
NO315453B1 (no) 2003-09-08
EP0758244A1 (fr) 1997-02-19
NO964678L (no) 1997-01-06
DE69524214D1 (de) 2002-01-10
SK143296A3 (en) 1998-07-08
AP9500735A0 (en) 1995-04-30
EP0758244B2 (fr) 2008-02-13
US20020044965A1 (en) 2002-04-18
MA23537A1 (fr) 1995-12-31
OA10320A (en) 1997-10-07
UY23958A1 (es) 1995-10-31
ATE209497T1 (de) 2001-12-15
HRP950277A2 (en) 1997-10-31
CO4290346A1 (es) 1996-04-17
BR9501929A (pt) 1996-03-05

Similar Documents

Publication Publication Date Title
AP548A (en) Controlled-release dosage forms of azithromycin.
JP4012689B2 (ja) 新規徐放性経口製剤
US4851232A (en) Drug delivery system with means for obtaining desirable in vivo release rate pattern
CA2268175C (fr) Forme posologique pharmaceutique comportant plusieurs enrobages polymeres enteriques, destinee a agir dans le colon
US5540945A (en) Pharmaceutical preparations for oral administration that are adapted to release the drug at appropriate sites in the intestines
CA2142653A1 (fr) Composition pharmaceutique
CA2290969C (fr) Formes posologiques de sertraline, a action retardee
CA2032475C (fr) Preparations pharmaceutiques pour administration par voie orale permettant la liberation du medicament dans des endroits cibles de l'intestin
WO2011039686A1 (fr) Formes pharmaceutiques orales à libération prolongée de latrépirdine
JP2005526739A (ja) コレステロール濃度を低下させる活性成分を含み、活性成分が遅延放出される薬剤
CA2379595A1 (fr) Formulations orales a liberation controlee
CZ118899A3 (cs) Kompozice s pozvolným uvolňováním léčiva, způsob přípravy této kompozice, způsob zlepšení profilu uvolňování léčiva a použití této kompozice
WO2006042277A2 (fr) Compositions a liberation prolongee d'inhibiteurs de pompes a protons
MXPA01002365A (en) New sustained release oral formulations
MXPA99012082A (en) Delayed-release dosage forms of sertraline