BR0307515A - Método para fabricar dispersões de drogas amorfas sólidas secas por aspersão homogêneas usando bicos de pressão - Google Patents

Método para fabricar dispersões de drogas amorfas sólidas secas por aspersão homogêneas usando bicos de pressão

Info

Publication number
BR0307515A
BR0307515A BR0307515-0A BR0307515A BR0307515A BR 0307515 A BR0307515 A BR 0307515A BR 0307515 A BR0307515 A BR 0307515A BR 0307515 A BR0307515 A BR 0307515A
Authority
BR
Brazil
Prior art keywords
pressure nozzles
amorphous drug
solid amorphous
dried solid
drug dispersions
Prior art date
Application number
BR0307515-0A
Other languages
English (en)
Inventor
Ronald Arthur Beyerrinck
Roderick Jack Ray
Daniel Elmont Dobry
Dana Marie Settell
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27663274&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0307515(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR0307515A publication Critical patent/BR0307515A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
  • Glanulating (AREA)
  • Disintegrating Or Milling (AREA)

Abstract

"MéTODO PARA FABRICAR DISPERSõES DE DROGAS AMORFAS SóLIDAS SECAS POR ASPERSãO HOMOGêNEAS USANDO BICOS DE PRESSãO". A presente invenção refere-se a dispersões amorfas sólidas homogêneas de drogas em polímeros potenciadores de concentração que são formadas em desejáveis tamanhos de partícula maiores com finas mínimas usando um atomizador e condições de processo capazes de produzir gotículas tendo um diâmetro de pelo menos 50 microns e um D~ 10~ de pelo menos 10 microns.
BR0307515-0A 2002-02-01 2003-01-20 Método para fabricar dispersões de drogas amorfas sólidas secas por aspersão homogêneas usando bicos de pressão BR0307515A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35398602P 2002-02-01 2002-02-01
PCT/IB2003/000120 WO2003063821A2 (en) 2002-02-01 2003-01-20 Method for making homogeneous spray-dried solid amorphous drug dispersions using pressure nozzles

Publications (1)

Publication Number Publication Date
BR0307515A true BR0307515A (pt) 2004-12-07

Family

ID=27663274

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0307515-0A BR0307515A (pt) 2002-02-01 2003-01-20 Método para fabricar dispersões de drogas amorfas sólidas secas por aspersão homogêneas usando bicos de pressão

Country Status (20)

Country Link
US (1) US7780988B2 (pt)
EP (1) EP1469830A2 (pt)
JP (1) JP2005523260A (pt)
KR (1) KR100758045B1 (pt)
CN (1) CN1787808A (pt)
AR (1) AR038369A1 (pt)
AU (1) AU2003239463B2 (pt)
BR (1) BR0307515A (pt)
CA (1) CA2474958A1 (pt)
GT (1) GT200300024A (pt)
MX (1) MXPA04007435A (pt)
PA (1) PA8565401A1 (pt)
PE (1) PE20030804A1 (pt)
PL (1) PL371593A1 (pt)
RS (1) RS67304A (pt)
RU (1) RU2288703C2 (pt)
TW (1) TW200404576A (pt)
UY (1) UY27645A1 (pt)
WO (1) WO2003063821A2 (pt)
ZA (1) ZA200405971B (pt)

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Also Published As

Publication number Publication date
US20030185893A1 (en) 2003-10-02
PL371593A1 (en) 2005-06-27
TW200404576A (en) 2004-04-01
CN1787808A (zh) 2006-06-14
RU2004123639A (ru) 2005-04-20
KR100758045B1 (ko) 2007-09-11
RS67304A (en) 2006-10-27
AU2003239463B2 (en) 2007-10-18
ZA200405971B (en) 2006-05-31
WO2003063821A3 (en) 2003-11-13
WO2003063821A2 (en) 2003-08-07
PA8565401A1 (es) 2003-12-10
PE20030804A1 (es) 2003-09-19
EP1469830A2 (en) 2004-10-27
MXPA04007435A (es) 2004-10-11
RU2288703C2 (ru) 2006-12-10
UY27645A1 (es) 2003-09-30
CA2474958A1 (en) 2003-08-07
KR20040083491A (ko) 2004-10-02
AR038369A1 (es) 2005-01-12
US7780988B2 (en) 2010-08-24
JP2005523260A (ja) 2005-08-04
GT200300024A (es) 2003-09-22

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE A 8.6 DA RPI 2116 DE 26/07/2011.