ZA927724B - Cyclic vasoactive peptides - Google Patents

Cyclic vasoactive peptides

Info

Publication number
ZA927724B
ZA927724B ZA927724A ZA927724A ZA927724B ZA 927724 B ZA927724 B ZA 927724B ZA 927724 A ZA927724 A ZA 927724A ZA 927724 A ZA927724 A ZA 927724A ZA 927724 B ZA927724 B ZA 927724B
Authority
ZA
South Africa
Prior art keywords
peptide
amino acid
cyclic
vasoactive
chain
Prior art date
Application number
ZA927724A
Other languages
English (en)
Inventor
David Robert Bolin
Margaret O'donnell
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ZA927724B publication Critical patent/ZA927724B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/17—Vasoactive intestinal peptides; related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA927724A 1991-10-11 1992-10-07 Cyclic vasoactive peptides ZA927724B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77374791A 1991-10-11 1991-10-11

Publications (1)

Publication Number Publication Date
ZA927724B true ZA927724B (en) 1994-04-07

Family

ID=25099195

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA927724A ZA927724B (en) 1991-10-11 1992-10-07 Cyclic vasoactive peptides

Country Status (26)

Country Link
US (1) US5677419A (fi)
EP (1) EP0536741B1 (fi)
JP (1) JP2515473B2 (fi)
KR (1) KR970001580B1 (fi)
CN (3) CN1034943C (fi)
AT (1) ATE132165T1 (fi)
AU (1) AU656230B2 (fi)
BG (1) BG61125B2 (fi)
BR (1) BR9203959A (fi)
CA (1) CA2080272C (fi)
CZ (1) CZ281818B6 (fi)
DE (1) DE69207138T2 (fi)
DK (1) DK0536741T3 (fi)
ES (1) ES2082317T3 (fi)
FI (2) FI111646B (fi)
GR (1) GR3019326T3 (fi)
HU (2) HUT62606A (fi)
IL (3) IL103396A (fi)
MX (1) MX9205822A (fi)
NO (3) NO304523B1 (fi)
NZ (1) NZ244644A (fi)
RU (1) RU2095368C1 (fi)
SK (1) SK279399B6 (fi)
TW (1) TW305846B (fi)
UY (2) UY23488A1 (fi)
ZA (1) ZA927724B (fi)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6872803B1 (en) 1993-09-21 2005-03-29 Kyowa Hakko Kogyo Co., Ltd. Peptides
EP0879246B1 (en) * 1996-02-09 2006-05-31 F. Hoffmann-La Roche Ag Synthesis of vip analog
AU725827B2 (en) 1996-07-12 2000-10-19 Immunomedics Inc. Radiometal-binding peptide analogues
WO1998002453A2 (en) * 1996-07-15 1998-01-22 Universite Libre De Bruxelles Peptidic ligands having a higher selectivity for the vip1 receptor than for the vip2 receptor
RU2269354C2 (ru) * 1999-09-28 2006-02-10 Байер Корпорейшн Агонисты рецептора-3(r3) пептида-активатора гипофизарной аденилатциклазы(расар) и способы их фармакологического применения
US6972319B1 (en) 1999-09-28 2005-12-06 Bayer Pharmaceuticals Corporation Pituitary adenylate cyclase activating peptide (PACAP)receptor 3 (R3) agonists and their pharmacological methods of use
AU2000263935A1 (en) 2000-02-18 2001-08-27 Dabur Research Foundation Radiolabeled vasoactive intestinal peptide analogs for diagnosis and radiotherapy
EP1257576B1 (en) * 2000-02-18 2004-09-15 Dabur Research Foundation Vasoactive intestinal peptide analogs
US6828304B1 (en) 2000-07-31 2004-12-07 Dabur Research Foundation Peptides for treatment of cancer
US7507714B2 (en) * 2000-09-27 2009-03-24 Bayer Corporation Pituitary adenylate cyclase activating peptide (PACAP) receptor 3 (R3) agonists and their pharmacological methods of use
AU2002220720B2 (en) 2000-11-28 2006-09-14 Mondobiotech Ag Compounds with the biological activity of vasoactive intestinal peptide for the treatment of pulmonary and arteriolar hypertension
DK1515745T3 (da) 2002-06-10 2009-07-13 Mondobiotech Ag Anvendelse af forbindelser med biologiskaktivitet af vasoaktivt intestinalt peptid til behandlingen af sarkoidose
BRPI0507177A (pt) * 2004-01-27 2007-06-26 Bayer Pharmaceuticals Corp agonistas (vpac2) do receptor peptìdico de ativação de adenilato ciclase pituitários (pacap) e seus métodos farmacológicos de uso
US20080085860A1 (en) * 2004-08-18 2008-04-10 Eli Lilly And Company Selective Vpac2 Receptor Peptide Agonists
CA2576217A1 (en) * 2004-08-18 2006-03-02 Eli Lilly And Company Selective vpac2 receptor peptide agonists
JP2009528376A (ja) * 2006-02-28 2009-08-06 イーライ リリー アンド カンパニー 選択的ｖｐａｃ２受容体ペプチドアゴニスト
AU2007271274A1 (en) * 2006-07-06 2008-01-10 F. Hoffmann-La Roche Ag Analogs of vasoactive intestinal peptide
CN101906144B (zh) * 2009-06-03 2013-06-19 首都医科大学 一根Arg-Gly-Asp-Val链通过Asp与两根脂肪醇链的偶联物、它们的合成及在医学中的应用
BR112012003327A2 (pt) 2009-08-14 2017-06-06 Phasebio Pharmaceuticals Inc peptídeos intestinais vasoativos modificados
WO2011133948A2 (en) * 2010-04-22 2011-10-27 Longevity Biotech, Inc. Highly active polypeptides and methods of making and using the same
ES2669190T3 (es) 2011-06-06 2018-05-24 Phasebio Pharmaceuticals, Inc. Uso de péptidos intestinales vasoactivos modificados en el tratamiento de la hipertensión
US9789164B2 (en) 2013-03-15 2017-10-17 Longevity Biotech, Inc. Peptides comprising non-natural amino acids and methods of making and using the same
GB201421647D0 (en) 2014-12-05 2015-01-21 Amcure Gmbh And Ruprecht-Karls-Universitat And Karlsruher Institut F�R Technologie CD44v6-derived cyclic peptides for treating cancers and angiogenesis related diseases
US10688156B2 (en) 2015-02-09 2020-06-23 Phasebio Pharmaceuticals, Inc. Methods and compositions for treating muscle disease and disorders
CN109790202B (zh) 2016-09-30 2022-09-13 富士胶片株式会社 环肽、亲和层析载体、标记抗体、抗体药物复合体及药物制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8427651D0 (en) * 1984-11-01 1984-12-05 Beecham Group Plc Compounds
US4835252A (en) * 1987-02-26 1989-05-30 The Salk Institute Biotechnology/Industrial Associates, Inc. Vasoactive intestinal peptide analogs
GB8729802D0 (en) * 1987-12-22 1988-02-03 Beecham Group Plc Novel compounds
US5084442A (en) * 1988-09-06 1992-01-28 Hoffmann-La Roche Inc. Cyclic growth hormone releasing factor analogs and method for the manufacture thereof
US5141924A (en) * 1989-06-30 1992-08-25 Hoffmann-La Roche, Inc. Synthetic vasoactive intestinal peptide analogs

Also Published As

Publication number Publication date
CA2080272A1 (en) 1993-04-12
CN1198841C (zh) 2005-04-27
KR970001580B1 (ko) 1997-02-11
IL117252A (en) 1999-11-30
IL103396A0 (en) 1993-03-15
NO980377D0 (no) 1998-01-28
CN1072415A (zh) 1993-05-26
HU9203194D0 (en) 1992-12-28
RU2095368C1 (ru) 1997-11-10
NO923929L (no) 1993-04-13
NZ244644A (en) 1995-04-27
UY23488A1 (es) 1993-04-20
HUT62606A (en) 1993-05-28
CZ308692A3 (en) 1993-08-11
NO975023L (no) 1993-04-13
ES2082317T3 (es) 1996-03-16
EP0536741B1 (en) 1995-12-27
FI20002041A (fi) 2000-09-15
NO975023D0 (no) 1997-10-31
UY25084A1 (es) 1998-12-21
CN1034943C (zh) 1997-05-21
NO923929D0 (no) 1992-10-09
SK279399B6 (sk) 1998-11-04
EP0536741A2 (en) 1993-04-14
BG61125B2 (bg) 1996-11-29
JPH05213996A (ja) 1993-08-24
DE69207138T2 (de) 1996-06-13
EP0536741A3 (fi) 1994-04-06
FI924580A (fi) 1993-04-12
CZ281818B6 (cs) 1997-02-12
FI924580A0 (fi) 1992-10-09
MX9205822A (es) 1993-06-01
TW305846B (fi) 1997-05-21
HU211534A9 (en) 1995-12-28
SK308692A3 (en) 1995-03-08
ATE132165T1 (de) 1996-01-15
KR930007972A (ko) 1993-05-20
CN1152579A (zh) 1997-06-25
IL117252A0 (en) 1996-06-18
CA2080272C (en) 2002-09-17
DK0536741T3 (da) 1996-04-22
JP2515473B2 (ja) 1996-07-10
NO980377L (no) 1993-04-13
NO304523B1 (no) 1999-01-04
FI111646B (fi) 2003-08-29
IL103396A (en) 1997-11-20
AU656230B2 (en) 1995-01-27
US5677419A (en) 1997-10-14
BR9203959A (pt) 1993-04-27
CN1225473C (zh) 2005-11-02
GR3019326T3 (en) 1996-06-30
DE69207138D1 (de) 1996-02-08
CN1153785A (zh) 1997-07-09
AU2622892A (en) 1993-04-22

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