ZA912550B - Dtpa monoamides,pharmaceutical agents containing these compounds,their use and process for their production - Google Patents

Dtpa monoamides,pharmaceutical agents containing these compounds,their use and process for their production

Info

Publication number
ZA912550B
ZA912550B ZA912550A ZA912550A ZA912550B ZA 912550 B ZA912550 B ZA 912550B ZA 912550 A ZA912550 A ZA 912550A ZA 912550 A ZA912550 A ZA 912550A ZA 912550 B ZA912550 B ZA 912550B
Authority
ZA
South Africa
Prior art keywords
group
hydrogen atom
radical
alkyl
denote
Prior art date
Application number
ZA912550A
Other languages
English (en)
Inventor
Heinz Gries
Gries Heinz
Erich Klieger
Klieger Erich
Bernd Raduechel
Raduechel Bernd
Heribert Schmitt-Willich
Schmitt-Willich Heribert
Hanns-Joachim Weinmann
Weinmann Hanns-Joachim
Hubert Vogler
Vogler Hubert
Juergen Conrad
Conrad Juergen
Gabriele Schuhmann-Giampieri
Schuhmann-Giampieri Gabriele
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of ZA912550B publication Critical patent/ZA912550B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/003—Compounds containing elements of Groups 3 or 13 of the Periodic Table without C-Metal linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/12—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02—Iron compounds
    • C07F15/025—Iron compounds without a metal-carbon linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA912550A 1990-04-06 1991-04-05 Dtpa monoamides,pharmaceutical agents containing these compounds,their use and process for their production ZA912550B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4011684A DE4011684A1 (de) 1990-04-06 1990-04-06 Dtpa-monoamide, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
ZA912550B true ZA912550B (en) 1992-01-29

Family

ID=6404192

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA912550A ZA912550B (en) 1990-04-06 1991-04-05 Dtpa monoamides,pharmaceutical agents containing these compounds,their use and process for their production

Country Status (16)

Country Link
US (4) US5859214A (es)
EP (1) EP0450742B1 (es)
JP (1) JP2854159B2 (es)
AT (1) ATE108179T1 (es)
AU (1) AU644639B2 (es)
CA (1) CA2039846A1 (es)
DE (2) DE4011684A1 (es)
DK (1) DK0450742T3 (es)
ES (1) ES2057746T3 (es)
FI (1) FI911646A (es)
HU (1) HUT57180A (es)
IE (1) IE65923B1 (es)
NO (1) NO180582C (es)
NZ (1) NZ237711A (es)
PT (1) PT97263B (es)
ZA (1) ZA912550B (es)

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US5817292A (en) * 1992-10-14 1998-10-06 Nycomed Imaging As MR imaging compositions and methods
DE4317588C2 (de) * 1993-05-24 1998-04-16 Schering Ag Fluorhaltige makrocyclische Metallkomplexe, Verfahren zu ihrer Herstellung, sowie ihre Verwendung
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US5582814A (en) * 1994-04-15 1996-12-10 Metasyn, Inc. 1-(p-n-butylbenzyl) DTPA for magnetic resonance imaging
US5672335A (en) * 1994-11-30 1997-09-30 Schering Aktiengesellschaft Use of metal complexes as liver and gallbladder X-ray diagnostic agents
CZ166797A3 (en) * 1994-11-30 1997-11-12 Schering Ag Application of metal complexes as liver and gallbladder x-ray diagnostic agents
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IL117200A0 (en) * 1995-02-21 1996-06-18 Schering Ag Diethylenetriamine-pentaacetic acid monoamide derivatives pharmaceutical compostions containing the same and processes for the preparation thereof
DE19507820A1 (de) * 1995-02-21 1996-08-22 Schering Ag Neuartig substituierte DTPA-Derivate, deren Metallkomplexe, diese Komplexe enthaltende pharmazeutische Mittel, deren Verwendung in der Diagnostik, sowie Verfahren zur Herstellung der Komplexe und Mittel
DE19507819A1 (de) * 1995-02-21 1996-08-22 Schering Ag DTPA-Monoamide der zentralen Carbonsäure und deren Metallkomplexe, diese Komplexe enthaltende pharmazeutische Mittel, deren Verwendung in der Diagnostik und Therapie sowie Verfahren zur Herstellung der Komplexe und Mittel
DE19507822B4 (de) * 1995-02-21 2006-07-20 Schering Ag Substituierte DTPA-Monoamide der zentralen Carbonsäure und deren Metallkomplexe, diese Komplexe enthaltende pharmazeutische Mittel, deren Verwendung in der Diagnostik und Therapie sowie Verfahren zur Herstellung der Komplexe und Mittel
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US6334995B1 (en) * 1998-03-24 2002-01-01 Council Of Scientific & Industrial Research Process for the preparation of technetium-99m diethylene triamine penta-acetic acid diester
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CN101010107A (zh) * 2004-08-26 2007-08-01 马林克罗特公司 监测肾功能的发光金属络合物
FI20065030L (fi) * 2006-01-17 2007-07-18 Wallac Oy Neutraaliset leimausreagenssit ja niistä johdetut konjugaatit
KR101336505B1 (ko) * 2006-08-17 2013-12-05 에픽스 파마슈티칼스, 인코포레이티드 림프계의 영상화 방법
US20110146787A1 (en) * 2008-05-28 2011-06-23 Sebastien Allen Silicon carbide-based antireflective coating
EP2480891B1 (en) 2009-09-24 2016-11-23 INSERM - Institut National de la Santé et de la Recherche Médicale Fkbp52-tau interaction as a novel therapeutical target for treating the neurological disorders involving tau dysfunction
EP2710381A2 (en) 2011-05-16 2014-03-26 Institut National de la Sante et de la Recherche Medicale (INSERM) Methods for screening substances capable of modulating the replication of an influenza virus
US20150276760A1 (en) 2012-10-04 2015-10-01 INSERM (Institut National de la Sante Et de la Recherche Medicate) Method for Screening a Compound Capable of Inhibiting the Notch1 Transcriptional Activity
WO2015124588A1 (en) 2014-02-18 2015-08-27 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of diseases mediated by the nrp-1/obr complex signaling pathway
EP3131922B1 (en) 2014-04-17 2020-05-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Polypeptides and uses thereof for reducing cd95-mediated cell motility
SG11201908911QA (en) * 2017-04-27 2019-11-28 Univ California Modified mri contrast agents and uses thereof
US11008354B2 (en) * 2018-05-24 2021-05-18 The Texas A&M University System Chiral solvating agents
EP3908680B1 (en) 2019-01-11 2023-03-01 Institut National de la Santé et de la Recherche Médicale (INSERM) Methods for screening inhibitors against chikungunya virus and for determining whether subjects are predisposed to infection by said virus
CN115043747B (zh) * 2022-08-15 2022-11-25 康瑞鑫(天津)药物研究院有限公司 卡洛酸三钠的析晶方法及制备的卡洛酸三钠晶体

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Also Published As

Publication number Publication date
NO911345D0 (no) 1991-04-05
EP0450742A1 (de) 1991-10-09
US5859214A (en) 1999-01-12
PT97263B (pt) 1998-08-31
AU644639B2 (en) 1993-12-16
JPH0665174A (ja) 1994-03-08
ATE108179T1 (de) 1994-07-15
US7074387B2 (en) 2006-07-11
CA2039846A1 (en) 1991-10-07
NO180582C (no) 1997-05-14
HU911126D0 (en) 1991-10-28
US6565830B1 (en) 2003-05-20
FI911646A (fi) 1991-10-07
ES2057746T3 (es) 1994-10-16
US6287538B1 (en) 2001-09-11
DE59102092D1 (de) 1994-08-18
DE4011684A1 (de) 1991-10-10
FI911646A0 (fi) 1991-04-05
PT97263A (pt) 1992-01-31
HUT57180A (en) 1991-11-28
DK0450742T3 (da) 1994-11-07
NO180582B (no) 1997-02-03
JP2854159B2 (ja) 1999-02-03
IE65923B1 (en) 1995-11-29
EP0450742B1 (de) 1994-07-06
NZ237711A (en) 1993-12-23
AU7418691A (en) 1991-10-10
NO911345L (no) 1991-10-07
US20030202943A1 (en) 2003-10-30
IE911155A1 (en) 1991-10-09

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