DK515288D0 - Fremgangsmaade til syntese af alpha-n-alkylerede aminosyrer og estere deraf - Google Patents
Fremgangsmaade til syntese af alpha-n-alkylerede aminosyrer og estere derafInfo
- Publication number
- DK515288D0 DK515288D0 DK515288A DK515288A DK515288D0 DK 515288 D0 DK515288 D0 DK 515288D0 DK 515288 A DK515288 A DK 515288A DK 515288 A DK515288 A DK 515288A DK 515288 D0 DK515288 D0 DK 515288D0
- Authority
- DK
- Denmark
- Prior art keywords
- synthesis
- alpha
- esters
- procedure
- amino acids
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8712902 | 1987-09-17 | ||
FR8712902A FR2620700B1 (fr) | 1987-09-17 | 1987-09-17 | Procede de synthese d'alpha amino acides n alkyles et leurs esters. application a la synthese de carboxyalkyl dipeptides |
Publications (3)
Publication Number | Publication Date |
---|---|
DK515288D0 true DK515288D0 (da) | 1988-09-15 |
DK515288A DK515288A (da) | 1989-03-18 |
DK173730B1 DK173730B1 (da) | 2001-08-06 |
Family
ID=9354994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK198805152A DK173730B1 (da) | 1987-09-17 | 1988-09-15 | Fremgangsmåde til syntese af Alpha-N-alkylerede aminosyrer og estere deraf samt mellemprodukt ved fremgangsmåden |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0309324B1 (da) |
JP (2) | JPH0725723B2 (da) |
AT (1) | ATE61567T1 (da) |
AU (1) | AU607260B2 (da) |
CA (1) | CA1341380C (da) |
DE (1) | DE3862006D1 (da) |
DK (1) | DK173730B1 (da) |
ES (1) | ES2034324T3 (da) |
FR (1) | FR2620700B1 (da) |
GR (1) | GR3001874T3 (da) |
HK (1) | HK55196A (da) |
IE (1) | IE60995B1 (da) |
NZ (1) | NZ226222A (da) |
OA (1) | OA08941A (da) |
PT (1) | PT88530B (da) |
ZA (1) | ZA886933B (da) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2620699B1 (fr) * | 1987-09-17 | 1990-06-01 | Adir | Procede de synthese d'alpha amino acides n alkyles et de leurs esters. application a la synthese de carboxyalkyl dipeptides |
DE19804100C1 (de) | 1998-02-03 | 1999-05-12 | Daimler Chrysler Ag | Fahrzeugsitz |
JP3892963B2 (ja) * | 1998-03-17 | 2007-03-14 | 住友化学株式会社 | L−バリンベンジルエステルp−トルエンスルホン酸塩の製造方法 |
US6706916B1 (en) | 1999-02-23 | 2004-03-16 | Toray Fine Chemicals Co., Ltd. | Optically active amino acid derivatives and processes for the preparation of the same |
JP2000247934A (ja) * | 1999-02-23 | 2000-09-12 | Toray Ind Inc | 高光学純度アミノ酸ベンジルエステルの製造法 |
FR2807431B1 (fr) | 2000-04-06 | 2002-07-19 | Adir | Nouveau procede de synthese du perindopril et de ses sels pharmaceutiquement acceptables |
FR2807430B1 (fr) * | 2000-04-11 | 2002-05-17 | Adir | Nouveau procede de synthese des esters de la n-[(s)-1- carboxybutyl]-(s)-alanine et application a la synthese du perindopril |
AR036187A1 (es) * | 2001-07-24 | 2004-08-18 | Adir | Un proceso para la preparacion de perindopril, compuestos analogos y sus sales, compuesto intermediario 2,5-dioxo-oxazolidina y proceso para preparar un intermediario |
SI1603558T1 (sl) | 2003-02-28 | 2008-12-31 | Servier S A Lab | Postopek za pripravo perindoprila in njegovih soli |
SI21800A (sl) | 2004-05-14 | 2005-12-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Nov postopek sinteze perindoprila |
EP1792896A1 (en) | 2005-12-01 | 2007-06-06 | KRKA, tovarna zdravil, d.d., Novo mesto | Process for the preparation of perindopril and salts thereof |
JP4929938B2 (ja) | 2006-09-12 | 2012-05-09 | 住友化学株式会社 | 光学活性なα−アミノ酸ベンジルエステル類の製造方法 |
JP5785045B2 (ja) * | 2011-10-06 | 2015-09-24 | エヌ・イーケムキャット株式会社 | 選択的脱ベンジル化方法およびこれに用いる選択水素化触媒 |
WO2016178591A2 (en) | 2015-05-05 | 2016-11-10 | Gene Predit, Sa | Genetic markers and treatment of male obesity |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2503155A2 (fr) * | 1980-10-02 | 1982-10-08 | Science Union & Cie | Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme |
US4344949A (en) * | 1980-10-03 | 1982-08-17 | Warner-Lambert Company | Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids |
US4296110A (en) * | 1980-10-28 | 1981-10-20 | E. I. Du Pont De Nemours And Company | Antihypertensive I-substituted cyclic lactam-2-carboxylic acids |
JPS6058233B2 (ja) * | 1982-05-24 | 1985-12-19 | 田辺製薬株式会社 | 2−オキソイミダゾリジン誘導体及びその製法 |
FR2620709B1 (fr) * | 1987-09-17 | 1990-09-07 | Adir | Procede de synthese industrielle du perindopril et de ses principaux intermediaires de synthese |
-
1987
- 1987-09-17 FR FR8712902A patent/FR2620700B1/fr not_active Expired - Lifetime
-
1988
- 1988-09-07 CA CA000577079A patent/CA1341380C/fr not_active Expired - Fee Related
- 1988-09-15 DK DK198805152A patent/DK173730B1/da active IP Right Grant
- 1988-09-16 AU AU22356/88A patent/AU607260B2/en not_active Expired
- 1988-09-16 EP EP19880402340 patent/EP0309324B1/fr not_active Expired - Lifetime
- 1988-09-16 ES ES198888402340T patent/ES2034324T3/es not_active Expired - Lifetime
- 1988-09-16 OA OA59436A patent/OA08941A/xx unknown
- 1988-09-16 DE DE8888402340T patent/DE3862006D1/de not_active Expired - Lifetime
- 1988-09-16 NZ NZ226222A patent/NZ226222A/xx unknown
- 1988-09-16 ZA ZA886933A patent/ZA886933B/xx unknown
- 1988-09-16 IE IE280788A patent/IE60995B1/en not_active IP Right Cessation
- 1988-09-16 JP JP63232122A patent/JPH0725723B2/ja not_active Expired - Lifetime
- 1988-09-16 AT AT88402340T patent/ATE61567T1/de not_active IP Right Cessation
- 1988-09-16 PT PT88530A patent/PT88530B/pt not_active IP Right Cessation
-
1991
- 1991-04-29 GR GR91400546T patent/GR3001874T3/el unknown
-
1994
- 1994-10-05 JP JP6241178A patent/JP2524489B2/ja not_active Expired - Lifetime
-
1996
- 1996-03-28 HK HK55196A patent/HK55196A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JPH01110651A (ja) | 1989-04-27 |
DK515288A (da) | 1989-03-18 |
HK55196A (en) | 1996-04-03 |
DK173730B1 (da) | 2001-08-06 |
JPH07206792A (ja) | 1995-08-08 |
JP2524489B2 (ja) | 1996-08-14 |
AU607260B2 (en) | 1991-02-28 |
DE3862006D1 (de) | 1991-04-18 |
EP0309324A1 (fr) | 1989-03-29 |
IE60995B1 (en) | 1994-09-07 |
ES2034324T3 (es) | 1993-04-01 |
GR3001874T3 (en) | 1992-11-23 |
NZ226222A (en) | 1990-06-26 |
OA08941A (fr) | 1989-10-31 |
JPH0725723B2 (ja) | 1995-03-22 |
ZA886933B (en) | 1989-05-30 |
EP0309324B1 (fr) | 1991-03-13 |
PT88530A (pt) | 1988-10-01 |
FR2620700B1 (fr) | 1990-06-01 |
PT88530B (pt) | 1992-11-30 |
ATE61567T1 (de) | 1991-03-15 |
FR2620700A1 (fr) | 1989-03-24 |
IE882807L (en) | 1989-03-17 |
CA1341380C (fr) | 2002-08-06 |
AU2235688A (en) | 1989-03-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) |