ZA912380B - Osmotic dosage system for liquid drug delivery - Google Patents

Osmotic dosage system for liquid drug delivery

Info

Publication number
ZA912380B
ZA912380B ZA912380A ZA912380A ZA912380B ZA 912380 B ZA912380 B ZA 912380B ZA 912380 A ZA912380 A ZA 912380A ZA 912380 A ZA912380 A ZA 912380A ZA 912380 B ZA912380 B ZA 912380B
Authority
ZA
South Africa
Prior art keywords
drug delivery
liquid drug
osmotic dosage
dosage system
beneficial agent
Prior art date
Application number
ZA912380A
Other languages
English (en)
Inventor
Patrick S-L Wong
S-L Wong Patrick
Felix Theeuwes
Theeuwes Felix
Brian L Barclay
L Barclay Brian
Michael Howard Dealey
Howard Dealey Michael
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of ZA912380B publication Critical patent/ZA912380B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • External Artificial Organs (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Spinning Or Twisting Of Yarns (AREA)
  • Paper (AREA)
  • Wrappers (AREA)
  • Materials For Medical Uses (AREA)
  • Detergent Compositions (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA912380A 1990-04-02 1991-03-28 Osmotic dosage system for liquid drug delivery ZA912380B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/502,705 US5324280A (en) 1990-04-02 1990-04-02 Osmotic dosage system for delivering a formulation comprising liquid carrier and drug

Publications (1)

Publication Number Publication Date
ZA912380B true ZA912380B (en) 1992-01-29

Family

ID=23999024

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA912380A ZA912380B (en) 1990-04-02 1991-03-28 Osmotic dosage system for liquid drug delivery

Country Status (17)

Country Link
US (2) US5324280A (pt)
EP (1) EP0523172B1 (pt)
JP (1) JP2927956B2 (pt)
KR (1) KR0176724B1 (pt)
AT (1) ATE116543T1 (pt)
AU (1) AU645315B2 (pt)
CA (1) CA2039456C (pt)
DE (1) DE69106501T2 (pt)
DK (1) DK0523172T3 (pt)
ES (1) ES2075444T3 (pt)
FI (1) FI924419A (pt)
IE (1) IE62394B1 (pt)
NO (1) NO923756L (pt)
NZ (1) NZ237642A (pt)
PT (1) PT97203B (pt)
WO (1) WO1991015196A1 (pt)
ZA (1) ZA912380B (pt)

Families Citing this family (186)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2693907B1 (fr) * 1992-07-23 1994-09-02 Rhone Poulenc Rorer Sa Procédé d'administration de solutions de facteur de stimulation des colonies granulocytaires.
US6440457B1 (en) * 1993-05-27 2002-08-27 Alza Corporation Method of administering antidepressant dosage form
WO1995010989A1 (en) * 1993-10-19 1995-04-27 Scimed Life Systems, Inc. Intravascular stent pump
US5496360A (en) * 1994-04-12 1996-03-05 Ventritex, Inc. Implantable cardiac electrode with rate controlled drug delivery
EP0768867B1 (en) * 1994-06-13 2002-10-09 Alza Corporation Dosage form for administering drug in liquid formulation
US5633011A (en) * 1994-08-04 1997-05-27 Alza Corporation Progesterone replacement therapy
US5718700A (en) * 1994-09-20 1998-02-17 Alza Corporation Exit means in dosage form
US5533973A (en) * 1995-01-13 1996-07-09 Abbott Laboratories Alteration of nutritional product during enteral tube feeding
US5531682A (en) * 1995-01-13 1996-07-02 Abbott Laboratories Apparatus for adding marker dye to nutritional product during enternal tube feeding
US6277092B1 (en) 1995-01-13 2001-08-21 Abbott Laboratories Apparatus for altering composition of nutritional product during enteral tube feeding
US5531681A (en) * 1995-01-13 1996-07-02 Abbott Laboratories Apparatus for altering composition of nutritional product during enteral tube feeding
US5531734A (en) * 1995-01-13 1996-07-02 Abbott Laboratories Method of altering composition of nutritional product during enteral tube feeding
US6036669A (en) 1995-01-13 2000-03-14 Abbott Laboratories Apparatus for altering composition of nutritional product during enteral tube feeding
FR2731154B1 (fr) * 1995-03-03 1997-05-09 Roussel Uclaf Compositions pharmaceutiques comprenant des derives de dinoreburnamenine
US5651979A (en) * 1995-03-30 1997-07-29 Gel Sciences, Inc. Apparatus and method for delivering a biologically active compound into a biological environment
US5800422A (en) * 1995-06-02 1998-09-01 Alza Corporation Osmotic device with delayed activation of drug delivery and complete drug release
EP0877599B1 (en) * 1996-02-02 2003-03-26 Alza Corporation Sustained delivery of leuprolide using an implantable system
US6261584B1 (en) 1996-02-02 2001-07-17 Alza Corporation Sustained delivery of an active agent using an implantable system
US6395292B2 (en) * 1996-02-02 2002-05-28 Alza Corporation Sustained delivery of an active agent using an implantable system
US6156331A (en) * 1996-02-02 2000-12-05 Alza Corporation Sustained delivery of an active agent using an implantable system
US6919373B1 (en) * 1996-11-12 2005-07-19 Alza Corporation Methods and devices for providing prolonged drug therapy
ATE223208T1 (de) * 1997-12-22 2002-09-15 Alza Corp Membranen zur steuerung des durchflusses in vorrichtungen mit kontrollierter wirkstoffabgabe
US6080132A (en) * 1998-02-27 2000-06-27 Abbott Laboratories Apparatus for altering characteristics of a fluid
US6099859A (en) * 1998-03-20 2000-08-08 Andrx Pharmaceuticals, Inc. Controlled release oral tablet having a unitary core
PT1077683E (pt) * 1998-05-14 2003-04-30 Alza Corp Terapia anti-depressiva
US6524620B2 (en) 1998-07-20 2003-02-25 Andrx Pharmaceuticals, Inc. Diltiazem controlled release formulation and method of manufacture
US6309373B1 (en) 1998-08-12 2001-10-30 Abbott Laboratories Apparatus for altering the characteristics of a fluid
US6183466B1 (en) 1998-08-21 2001-02-06 Alza Corporation Dosage form comprising a capsule
US6099862A (en) * 1998-08-31 2000-08-08 Andrx Corporation Oral dosage form for the controlled release of a biguanide and sulfonylurea
US6551613B1 (en) * 1998-09-08 2003-04-22 Alza Corporation Dosage form comprising therapeutic formulation
US6174547B1 (en) * 1999-07-14 2001-01-16 Alza Corporation Dosage form comprising liquid formulation
WO2000013663A1 (en) * 1998-09-09 2000-03-16 Alza Corporation Dosage form comprising liquid formulation
US20090297602A1 (en) * 1998-11-02 2009-12-03 Devane John G Modified Release Loxoprofen Compositions
US6706282B1 (en) * 1998-11-02 2004-03-16 Evangeline Cruz Controlled delivery of phenoxyethyl-substituted 1,2,4-triazolones
GB9824658D0 (en) * 1998-11-11 1999-01-06 Brown Malcolm D A capsule based drug delivery system
MXPA01006108A (es) * 1998-12-17 2002-09-18 Alza Corp Conversion de capsulas de gelatina rellenas de liquido en sistemas de liberacion controlada mediante multiples recubrimientos.
PT1140039E (pt) 1998-12-18 2010-02-03 Alza Corp Dispositivos transparentes de administração transdérmica de nicotina
US6198966B1 (en) 1999-02-26 2001-03-06 Medtronic, Inc. Recirculating implantable drug delivery system
US20040121014A1 (en) * 1999-03-22 2004-06-24 Control Delivery Systems, Inc. Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6217895B1 (en) * 1999-03-22 2001-04-17 Control Delivery Systems Method for treating and/or preventing retinal diseases with sustained release corticosteroids
JP3061616B1 (ja) * 1999-04-09 2000-07-10 株式会社セラリカ野田 低カロリ―調製ロ―ヤルゼリ―
DE19923817A1 (de) * 1999-05-18 2000-11-23 Roland Bodmeier Kapsel mit kontrollierter Wirkstofffreisetzung
US20060015075A1 (en) * 1999-06-22 2006-01-19 Erblan Surgical Inc. Guarded infusor needle and infusor locking system
US20040230155A1 (en) * 1999-06-22 2004-11-18 Erblan Surgical Inc. Insufflator and method of use
US6251432B1 (en) 1999-07-01 2001-06-26 Abbott Laboratories Sustained release dosage form unit having latex coating and method of making the same
EP1239840B1 (en) 1999-12-09 2005-04-06 Alza Corporation Antiviral medication
AR026148A1 (es) * 2000-01-21 2003-01-29 Osmotica Argentina S A Dispositivo osmotico con pasaje preformado que aumenta de tamano
CA2399000C (en) * 2000-02-04 2009-12-22 Alza Corporation Osmotically-driven fluid dispenser and coating composition
US6464688B1 (en) 2000-02-15 2002-10-15 Microsolutions, Inc. Osmotic pump delivery system with flexible drug compartment
GB0003424D0 (en) * 2000-02-16 2000-04-05 Bioprogress Tech Int Inc A controlled release capsule
GB2398499B (en) * 2000-02-16 2004-11-24 Bioprogress Technology Ltd Two layer capsules
US6375972B1 (en) 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
US6468559B1 (en) * 2000-04-28 2002-10-22 Lipocine, Inc. Enteric coated formulation of bishosphonic acid compounds and associated therapeutic methods
US20020161387A1 (en) * 2000-06-22 2002-10-31 Blanco Ernesto E. Safety trocar with progressive cutting tip guards and gas jet tissue deflector
US20040230160A1 (en) * 2000-06-22 2004-11-18 Erblan Surgical Inc. Safety trocar including sealing member
US20020198215A1 (en) * 2000-10-23 2002-12-26 Lino Tavares Terazosin transdermal device and methods
US20060034922A1 (en) * 2000-11-03 2006-02-16 Andrx Labs, Llc Controlled release metformin compositions
EP1450836A4 (en) * 2000-11-03 2007-07-25 Intarcia Therapeutics Inc PROCESS FOR SHORT AND LONG-TERM DOSAGE OF MEDICAMENTS
US6866866B1 (en) * 2000-11-03 2005-03-15 Andrx Labs, Llc Controlled release metformin compositions
US6790459B1 (en) 2000-11-03 2004-09-14 Andrx Labs, Llc Methods for treating diabetes via administration of controlled release metformin
DE10100689A1 (de) * 2001-01-09 2002-07-18 Henkel Kgaa Wasch- und reinigungsaktive Substanzen enthaltende Mikrokapseln
US6632217B2 (en) 2001-04-19 2003-10-14 Microsolutions, Inc. Implantable osmotic pump
EP2316394B1 (en) 2001-06-12 2016-11-23 The Johns Hopkins University Reservoir device for intraocular drug delivery
US7163688B2 (en) * 2001-06-22 2007-01-16 Alza Corporation Osmotic implant with membrane and membrane retention means
US7083578B2 (en) * 2001-07-12 2006-08-01 Given Imaging Ltd. Device and method for examining a body lumen
US7349733B2 (en) * 2001-11-02 2008-03-25 Ceramatel, Inc. Iontophoretic drug delivery systems
CA2466228A1 (en) * 2001-11-09 2003-08-07 Biomedicines, Inc. Method for treating diseases with omega interferon
CA2471096A1 (en) * 2001-12-19 2003-07-03 Alza Corporation Formulation and dosage form for increasing oral bioavailability of hydrophilic macromolecules
AU2002357930B2 (en) * 2001-12-19 2007-06-28 Alza Corporation Formulation & dosage form for the controlled delivery of therapeutic agents
US7047069B2 (en) 2002-02-04 2006-05-16 Ceramatec, Inc. Iontophoretic fluid delivery device
US6775570B2 (en) 2002-02-04 2004-08-10 Ceramatec, Inc. Iontophoretic treatment device
US8871241B2 (en) * 2002-05-07 2014-10-28 Psivida Us, Inc. Injectable sustained release delivery devices
AU2003241537A1 (en) * 2002-05-23 2003-12-12 Andrx Corporation Biguanide formulations
EP1536767B1 (en) * 2002-06-17 2007-08-08 Alza Corporation Osmotic delivery system with early zero order push power engine comprising an osmotic agent dispersed in the fluid vehicle
AR039744A1 (es) * 2002-06-26 2005-03-09 Alza Corp Metodos y formas de dosificacion para aumentar la solubilidad de las composiciones de farmacos para la administracion controlada
MXPA05000224A (es) * 2002-06-26 2005-06-03 Alza Corp Piston de volumen eficiente, minimamente deformable, para sistemas de suministro osmotico de farmacos.
TW200414900A (pt) * 2002-06-28 2004-08-16
US20050232995A1 (en) 2002-07-29 2005-10-20 Yam Nyomi V Methods and dosage forms for controlled delivery of paliperidone and risperidone
AU2003256848A1 (en) * 2002-07-29 2004-02-16 Alza Corporation Formulations and dosage forms for controlled delivery of topiramate
WO2004041255A1 (en) * 2002-10-31 2004-05-21 Alza Corporation Dosage form providing ascending release of liquid formulation
UY28057A1 (es) * 2002-10-31 2003-12-31 Alza Corp Formulacion y forma de dosificacion que provee mayor biodisponibilidad de los farmacos hidrófobos
US7014636B2 (en) * 2002-11-21 2006-03-21 Alza Corporation Osmotic delivery device having a two-way valve and a dynamically self-adjusting flow channel
US7491234B2 (en) * 2002-12-03 2009-02-17 Boston Scientific Scimed, Inc. Medical devices for delivery of therapeutic agents
NZ539915A (en) * 2002-12-11 2007-09-28 Pfizer Prod Inc Controlled-release of an active substance into a high fat environment
US7731947B2 (en) * 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
CN1842321B (zh) * 2003-06-26 2012-07-04 控制递送系统有限公司 生物蚀解性缓释递药系统
PL1635875T3 (pl) 2003-06-26 2009-03-31 Psivida Inc System dostarczania leków poprzez żelowanie w warunkach in-situ
DK1635787T3 (da) * 2003-06-26 2012-03-26 Control Delivery Sys Inc Bioeroderbare lægemiddelafgivelsessystemer med forhalet frigivelse
AU2004264316A1 (en) * 2003-08-06 2005-02-24 Alza Corporation Uniform delivery of topiramate over prolonged period of time with enhanced dispersion formulation
WO2005020957A2 (en) * 2003-08-22 2005-03-10 Alza Corporation Stepwise delivery of topiramate over prolonged period of time
AU2004268661A1 (en) * 2003-09-02 2005-03-10 Alza Corporation Novel drug compositions and dosage forms of topiramate
WO2005048981A1 (en) * 2003-11-14 2005-06-02 Alza Corporation Controlled release of topirimate in liquid dosage forms
KR20060123493A (ko) * 2003-12-23 2006-12-01 알자 코포레이션 제어된 전달을 위한 약물 조성물의 용해도를 증가시키는방법 및 제형
EP1701708A2 (en) * 2003-12-29 2006-09-20 Alza Corporation Novel drug compositions and dosage forms of topiramate
AU2004312082A1 (en) * 2003-12-29 2005-07-21 Alza Corporation, Inc. Novel drug compositions and dosage forms
US20050175696A1 (en) * 2003-12-29 2005-08-11 David Edgren Drug granule coatings that impart smear resistance during mechanical compression
NZ582466A (en) * 2004-07-30 2011-09-30 Adeza Biomedical Corp Oncofetal fibronectin as a marker for disease and other conditions and methods for detection of oncofetal fibronectin
US20060045891A1 (en) * 2004-08-24 2006-03-02 Lovalenti Phillip M Density-matched suspension vehicles and pharmaceutical suspensions
US20060165798A1 (en) * 2005-01-27 2006-07-27 Edgren David E Oral osmotic dosage form having a high flux membrane
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
JP2008536928A (ja) * 2005-04-19 2008-09-11 アルザ・コーポレーシヨン トラマドール及び、ガバペンチンを含んでなる物質、の組み合わせ物
EP1898920A1 (en) * 2005-06-02 2008-03-19 Thallion Pharmaceuticals Inc. Formulation comprising farnesyl dibenzodiazepinone and a pharmaceutically acceptable surfactant
WO2007011972A2 (en) * 2005-07-19 2007-01-25 Inverseon, Inc. Improved pharmacokinetic profile of beta-adrenergic inverse agonists for the treatment of pulmonary airway diseases
AR055099A1 (es) * 2005-07-28 2007-08-08 Alza Corp Formulaciones liquidas para la administracion controlada de derivados de bencisoxazol
US20070212397A1 (en) * 2005-09-15 2007-09-13 Roth Daniel B Pharmaceutical delivery device and method for providing ocular treatment
PL116330U1 (en) 2005-10-31 2007-04-02 Alza Corp Method for the reduction of alcohol provoked rapid increase in the released dose of the orally administered opioide with prolonged liberation
US20070196487A1 (en) * 2006-02-16 2007-08-23 Geerke Johan H Method and apparatus for drilling orifices in osmotic tablets incorporating near-infrared spectroscopy
DE602007009377D1 (de) 2006-05-30 2010-11-04 Intarcia Therapeutics Inc Zweiteiliger flussmodulator mit einem internen kanal für ein osmotisches ausgabesystem
EP3421031A1 (en) * 2006-08-09 2019-01-02 Intarcia Therapeutics, Inc Osmotic delivery systems and piston assemblies
US20080177219A1 (en) * 2007-01-23 2008-07-24 Joshi Ashok V Method for Iontophoretic Fluid Delivery
US8524749B2 (en) * 2007-02-09 2013-09-03 Alza Corporation Controlled release compositions of tizanidine
GB0707127D0 (en) * 2007-04-13 2007-05-23 Zysis Ltd Pharmaceutical compositions
KR101208381B1 (ko) 2007-04-23 2012-12-05 인타르시아 세라퓨틱스 인코포레이티드 인슐린자극 펩티드의 현탁 제형 및 이의 용도
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
US20090087484A1 (en) * 2007-09-28 2009-04-02 Alza Corporation Formulation and dosage form for increasing oral bioavailability of hydrophilic macromolecules
US20090110724A1 (en) * 2007-10-31 2009-04-30 Everett Laboratories, Inc. Compositions and methods for treatment of pain
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
DK2240155T3 (da) 2008-02-13 2012-09-17 Intarcia Therapeutics Inc Indretninger, formuleringer og fremgangsmåder til levering af flere gavnlige midler
US20090311335A1 (en) * 2008-06-12 2009-12-17 Scott Jenkins Combination of a triptan and an nsaid
US20090312627A1 (en) * 2008-06-16 2009-12-17 Matott Laura A Radio-labeled ingestible capsule
CA2638240C (en) * 2008-08-29 2010-02-02 Alexander Macgregor Method of treating dysglycemia and glucose excursions
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
CA2757037C (en) 2009-01-29 2019-08-06 Forsight Vision4, Inc. Posterior segment drug delivery
EP2416764A4 (en) * 2009-04-09 2013-09-04 Alkermes Pharma Ireland Ltd COMPOSITION FOR ACTIVE COMPOSITION
CN105726201B (zh) * 2009-05-18 2020-08-25 多斯医学公司 给药眼植入物
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
SG176785A1 (en) 2009-06-16 2012-01-30 Pfizer Dosage forms of apixaban
WO2011006066A1 (en) 2009-07-10 2011-01-13 Ironwood Pharmaceuticals, Inc. Cb receptor agonists
JP5600174B2 (ja) * 2009-09-15 2014-10-01 チーム アカデミー オブ ファーマシューティカル サイエンス 浸透圧ポンプ型放出制御錠及びその製造方法
EP2462246B1 (en) 2009-09-28 2017-09-06 Intarcia Therapeutics, Inc Rapid establishment and/or termination of substantial steady-state drug delivery
EP2515759A4 (en) 2009-12-23 2015-01-21 Given Imaging Inc METHOD OF ASSESSING CONSTIPATION USING INGREDIENT CAPSULE
JP2013515741A (ja) * 2009-12-23 2013-05-09 サイヴィーダ ユーエス,インコーポレイテッド 持続放出性送達デバイス
EA201200855A1 (ru) 2009-12-23 2013-04-30 Айронвуд Фармасьютикелз, Инк. Модуляторы crth2
WO2013022801A1 (en) 2011-08-05 2013-02-14 Forsight Vision4, Inc. Small molecule delivery with implantable therapeutic device
WO2011100359A1 (en) 2010-02-09 2011-08-18 Ironwood Pharmaceuticals, Inc. Cannabinoid agonists
WO2011100324A1 (en) 2010-02-09 2011-08-18 Ironwood Pharmaceuticals Inc. Cannabinoid receptor agonists
WO2011115804A1 (en) 2010-03-17 2011-09-22 Ironwood Pharmaceuticals, Inc. Sgc stimulators
TWI582091B (zh) 2010-06-30 2017-05-11 艾諾屋製藥公司 可溶性鳥苷酸環化酶(sGC)刺激物
US20130259830A1 (en) 2010-07-12 2013-10-03 Ironwood Pharmaceuticals, Inc. Crth2 modulators
US20130216552A1 (en) 2010-07-12 2013-08-22 Ironwood Pharmaceuticals, Inc. Crth2 modulators
AU2011285548B2 (en) 2010-08-05 2014-02-06 Forsight Vision4, Inc. Combined drug delivery methods and apparatus
AU2011285545B2 (en) 2010-08-05 2014-03-13 Forsight Vision4, Inc. Injector apparatus and method for drug delivery
HUE057267T2 (hu) 2010-08-05 2022-05-28 Forsight Vision4 Inc Berendezés szem kezelésére
CN103118610B (zh) 2010-08-30 2016-03-02 西努赛斯公司 用于扩张鼻旁窦开口和用于治疗鼻窦炎的装置
ES2572803T3 (es) 2010-11-09 2016-06-02 Ironwood Pharmaceuticals, Inc. Estimuladores de GCs
CA2818612C (en) 2010-11-19 2020-12-29 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
WO2013003620A2 (en) 2011-06-28 2013-01-03 Forsight Vision4, Inc. Diagnostic methods and apparatus
ES2864203T3 (es) 2011-09-16 2021-10-13 Forsight Vision4 Inc Aparato de intercambio de fluido
CN104066731B (zh) 2011-12-27 2016-06-15 铁木医药有限公司 可用作sgc刺激剂的2-苄基、3-(嘧啶-2-基)取代的吡唑类
US10010448B2 (en) 2012-02-03 2018-07-03 Forsight Vision4, Inc. Insertion and removal methods and apparatus for therapeutic devices
CA2862297A1 (en) 2012-02-29 2013-09-06 SinuSys Corporation Devices and methods for dilating a paranasal sinus opening and for treating sinusitis
WO2013155422A1 (en) 2012-04-12 2013-10-17 Ironwood Pharmaceuticals, Inc. Methods of treating alopecia and acne
WO2014047111A1 (en) 2012-09-18 2014-03-27 Ironwood Pharmaceuticals, Inc. Sgc stimulators
CA2885645A1 (en) 2012-09-19 2014-03-27 Ironwood Pharmaceuticals, Inc. Sgc stimulators
CA2905496A1 (en) 2013-03-14 2014-09-25 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
MX361208B (es) 2013-03-15 2018-11-30 Ironwood Pharmaceuticals Inc Estimuladores de guanilato ciclasa soluble (sgc).
EP4302736A3 (en) 2013-03-28 2024-04-03 ForSight Vision4, Inc. Ophthalmic implant for delivering therapeutic substances
US9687263B2 (en) 2013-05-30 2017-06-27 SinuSys Corporation Devices and methods for inserting a sinus dilator
KR102385603B1 (ko) * 2013-08-19 2022-04-11 타리스 바이오메디컬 엘엘씨 다중 유닛 약물 전달 장치 및 방법
CA2932290C (en) 2013-12-06 2023-06-13 Durect Corporation Compositions comprising antioxidant, fluid dispensers, and methods involving the same
WO2015089182A1 (en) 2013-12-11 2015-06-18 Ironwood Pharmaceuticals, Inc. Sgc stimulators
AU2015266850B2 (en) 2014-05-29 2019-12-05 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
KR102416726B1 (ko) 2014-07-15 2022-07-05 포사이트 비젼4, 인크. 안구 이식물 전달 디바이스 및 방법
WO2016022750A1 (en) 2014-08-08 2016-02-11 Forsight Vision4, Inc. Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof
EP3194386A2 (en) 2014-09-17 2017-07-26 Ironwood Pharmaceuticals, Inc. Sgc stimulators
US20170298055A1 (en) 2014-09-17 2017-10-19 Ironwood Pharmaceuticals, Inc. sGC STIMULATORS
CA2959757A1 (en) 2014-09-17 2016-03-24 Ironwood Pharmaceuticals, Inc. Pyrazole derivatives as sgc stimulators
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
CN114587774A (zh) 2014-11-10 2022-06-07 弗赛特影像4股份有限公司 治疗眼睛的系统
EP4278996A3 (en) 2015-06-03 2024-01-24 i2o Therapeutics, Inc. Implant placement systems
WO2017040853A1 (en) 2015-09-02 2017-03-09 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
US11564833B2 (en) 2015-09-25 2023-01-31 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
AU2016355345A1 (en) 2015-11-20 2018-05-31 Forsight Vision4, Inc. Porous structures for extended release drug delivery devices
AR108177A1 (es) 2016-04-05 2018-07-25 Forsight Vision4 Inc Dispositivos de suministro de fármacos oculares implantables
CN109937025B (zh) 2016-04-20 2022-07-29 多斯医学公司 生物可吸收眼部药物的递送装置
AU2017268161B2 (en) 2016-05-16 2020-03-12 Intarcia Therapeutics, Inc. Glucagon-receptor selective polypeptides and methods of use thereof
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
MX2021007580A (es) 2016-09-02 2022-08-23 Cyclerion Therapeutics Inc Estimuladores de guanilato ciclasa soluble (sgc) biciclicos fusionados.
JP7150740B2 (ja) 2016-11-08 2022-10-11 サイクレリオン・セラピューティクス,インコーポレーテッド sGC刺激薬による中枢神経系疾患の治療
SG10202104876SA (en) 2016-11-08 2021-06-29 Cyclerion Therapeutics Inc Sgc stimulators
CN110225762A (zh) 2017-01-03 2019-09-10 因塔西亚制药公司 包括glp-1受体激动剂的连续施用和药物的共同施用的方法
CA3082891A1 (en) 2017-11-21 2019-05-31 Forsight Vision4, Inc. Fluid exchange apparatus for expandable port delivery system and methods of use
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3760805A (en) * 1971-01-13 1973-09-25 Alza Corp Osmotic dispenser with collapsible supply container
US3995631A (en) * 1971-01-13 1976-12-07 Alza Corporation Osmotic dispenser with means for dispensing active agent responsive to osmotic gradient
US4138013A (en) * 1976-08-27 1979-02-06 Parke, Davis & Company Enteric capsules
US4180073A (en) * 1977-08-29 1979-12-25 Alza Corporation Device for delivering drug to biological environment
US4203442A (en) * 1977-08-29 1980-05-20 Alza Corporation Device for delivering drug to a fluid environment
US4203440A (en) * 1978-10-23 1980-05-20 Alza Corporation Device having variable volume chamber for dispensing useful agent
US4203441A (en) * 1978-12-18 1980-05-20 Alza Corporation Osmotically triggered device with gas generating means
FR2524311A1 (fr) * 1982-04-05 1983-10-07 Azalbert Gilles Gelule compartimentee aux fins d'ingestions simultanees a effets differes
AU591171B2 (en) * 1983-11-02 1989-11-30 Alza Corporation Dispenser for delivering thermo-responsive composition
US4781714A (en) * 1983-11-02 1988-11-01 Alza Corporation Dispenser for delivering thermo-responsive composition
US4627850A (en) * 1983-11-02 1986-12-09 Alza Corporation Osmotic capsule
US4693886A (en) * 1985-04-22 1987-09-15 Alza Corporation Osmotic device with inert core
US4842867A (en) * 1986-05-09 1989-06-27 Alza Corporation Pulsed drug delivery of doxylamine
US4929233A (en) * 1988-08-26 1990-05-29 Alza Corporation Implantable fluid imbibing pump with improved closure

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AU7673791A (en) 1991-10-30
DE69106501D1 (de) 1995-02-16
NO923756L (no) 1992-12-02
PT97203A (pt) 1991-12-31
IE911040A1 (en) 1991-10-09
AU645315B2 (en) 1994-01-13
DE69106501T2 (de) 1995-05-11
DK0523172T3 (da) 1995-07-10
EP0523172A1 (en) 1993-01-20
US5413572A (en) 1995-05-09
ATE116543T1 (de) 1995-01-15
EP0523172B1 (en) 1995-01-04
JP2927956B2 (ja) 1999-07-28
JPH07502252A (ja) 1995-03-09
NO923756D0 (no) 1992-09-28
IE62394B1 (en) 1995-01-25
PT97203B (pt) 1999-03-31
KR0176724B1 (ko) 1999-03-20
CA2039456C (en) 2003-11-11
FI924419A0 (fi) 1992-10-01
FI924419A (fi) 1992-10-01
US5324280A (en) 1994-06-28
NZ237642A (en) 1993-07-27
CA2039456A1 (en) 1991-10-03
WO1991015196A1 (en) 1991-10-17
ES2075444T3 (es) 1995-10-01

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