UY28057A1 - Formulacion y forma de dosificacion que provee mayor biodisponibilidad de los farmacos hidrófobos - Google Patents
Formulacion y forma de dosificacion que provee mayor biodisponibilidad de los farmacos hidrófobosInfo
- Publication number
- UY28057A1 UY28057A1 UY28057A UY28057A UY28057A1 UY 28057 A1 UY28057 A1 UY 28057A1 UY 28057 A UY28057 A UY 28057A UY 28057 A UY28057 A UY 28057A UY 28057 A1 UY28057 A1 UY 28057A1
- Authority
- UY
- Uruguay
- Prior art keywords
- formulation
- hydrophobic
- dosage
- pharmacos
- biodisponibility
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Provee una formulación del fármaco y una forma de dosificación. La formulación del fármaco cumple la función de incrementar la biodisponibilidad de los fármacos hidrófobos administrados al tracto gastrointestinal ("tracto GI") de un sujeto determinado. La forma de dosificación, puede formarse utilizando varios materiales diferentes y puede configurarse para administrar la formulación del fármaco de la presente invención al tracto GI de un sujeto utilizando cualquier mecanismo adecuado.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42318402P | 2002-10-31 | 2002-10-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY28057A1 true UY28057A1 (es) | 2003-12-31 |
Family
ID=32312618
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY28057A UY28057A1 (es) | 2002-10-31 | 2003-10-31 | Formulacion y forma de dosificacion que provee mayor biodisponibilidad de los farmacos hidrófobos |
Country Status (11)
Country | Link |
---|---|
US (1) | US20040142040A1 (es) |
EP (1) | EP1556000A1 (es) |
JP (1) | JP2006507309A (es) |
KR (1) | KR20050083875A (es) |
CN (1) | CN1728982A (es) |
AR (1) | AR041745A1 (es) |
AU (1) | AU2003291667A1 (es) |
CA (1) | CA2504031A1 (es) |
TW (1) | TW200423968A (es) |
UY (1) | UY28057A1 (es) |
WO (1) | WO2004041246A1 (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2003230885A1 (en) * | 2002-04-12 | 2003-10-27 | Elan Pharma International Ltd. | Nanoparticulate megestrol formulations |
US9101540B2 (en) | 2002-04-12 | 2015-08-11 | Alkermes Pharma Ireland Limited | Nanoparticulate megestrol formulations |
US20060047025A1 (en) * | 2004-06-29 | 2006-03-02 | Matthew Piazza | Viscous materials and method for producing |
EP1791520A2 (en) * | 2004-08-19 | 2007-06-06 | Alza Corporation | Controlled release nanoparticle active agent formulation dosage forms and methods |
KR101327649B1 (ko) * | 2005-03-31 | 2013-11-12 | 산토리 홀딩스 가부시키가이샤 | 리그난류 화합물 함유 수중 유적형 에멀션 및 그것을함유하는 조성물 |
KR100682531B1 (ko) | 2005-04-06 | 2007-02-15 | 유효경 | 양쪽성 계면활성제와 폴리올을 함유하는 가용화용나노조성물 |
US20070077309A1 (en) * | 2005-09-30 | 2007-04-05 | Wong Patrick S | Banded controlled release nanoparticle active agent formulation dosage forms and methods |
BRPI0713533A2 (pt) * | 2006-06-26 | 2012-04-17 | Mutual Pharmaceutical Co | formulações de agente ativo, métodos de fabricação, e métodos de uso |
WO2008044550A1 (fr) * | 2006-10-04 | 2008-04-17 | Suntory Limited | Émulsion de type huile/eau/huile contenant un composé de lignane, et composition la contenant |
EP2200613B1 (en) | 2007-09-21 | 2018-09-05 | The Johns Hopkins University | Phenazine derivatives and uses thereof |
IT1393245B1 (it) * | 2008-07-24 | 2012-04-12 | Universita' Degli Studi Di Milano | Forme farmaceutiche per il rilascio tempo-specifico di farmaci |
US20100159010A1 (en) * | 2008-12-24 | 2010-06-24 | Mutual Pharmaceutical Company, Inc. | Active Agent Formulations, Methods of Making, and Methods of Use |
US8993625B2 (en) | 2009-03-11 | 2015-03-31 | Stable Solutions Llc | Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle |
US20110071090A1 (en) * | 2009-03-11 | 2011-03-24 | Stable Solutions Llc | Method of mitigating adverse drug events using omega-3-fatty acids as a parenteral therapeutic drug vehicle |
US9034389B2 (en) | 2009-03-11 | 2015-05-19 | Stable Solutions Llc | Omega-3 enriched fish oil-in-water parenteral nutrition emulsions |
US9431262B2 (en) | 2014-03-14 | 2016-08-30 | Fujikoshi Machinery Corp. | Method for polishing work and work polishing apparatus |
AU2015341479B2 (en) * | 2014-11-04 | 2020-11-26 | Innopharmax, Inc. | Oral administration of unstable or poorly-absorbed drugs |
GB2541387A (en) * | 2015-08-14 | 2017-02-22 | Res Center Pharmaceutical Eng Gmbh | Self-emulsifying Nanosuspensions as Drug Delivery Systems (SENDDS) |
PL428779A1 (pl) * | 2019-01-31 | 2020-08-10 | Gdański Uniwersytet Medyczny | Kompozycja farmaceutyczna w postaci ciekłej zawierająca jako substancję aktywną substancję leczniczą nietrwałą w środowisku wodnym |
Family Cites Families (38)
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US534280A (en) * | 1895-02-19 | Hose-leak stop or jacket | ||
US3845770A (en) * | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
US3916899A (en) * | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
US4077407A (en) * | 1975-11-24 | 1978-03-07 | Alza Corporation | Osmotic devices having composite walls |
US4200098A (en) * | 1978-10-23 | 1980-04-29 | Alza Corporation | Osmotic system with distribution zone for dispensing beneficial agent |
US4627850A (en) * | 1983-11-02 | 1986-12-09 | Alza Corporation | Osmotic capsule |
US4627851A (en) * | 1984-10-26 | 1986-12-09 | Alza Corporation | Colonic-therapeutic delivery system |
US4915949A (en) * | 1987-07-13 | 1990-04-10 | Alza Corporation | Dispenser with movable matrix comprising a plurality of tiny pills |
US5160743A (en) * | 1988-04-28 | 1992-11-03 | Alza Corporation | Annealed composition for pharmaceutically acceptable drug |
US4931285A (en) * | 1988-04-28 | 1990-06-05 | Alza Corporation | Aqueous based pharmaceutical coating composition for dosage forms |
US5006346A (en) * | 1988-04-28 | 1991-04-09 | Alza Corporation | Delivery system |
US5024842A (en) * | 1988-04-28 | 1991-06-18 | Alza Corporation | Annealed coats |
US5126142A (en) * | 1989-07-18 | 1992-06-30 | Alza Corporation | Dispenser comprising ionophore |
US5324280A (en) * | 1990-04-02 | 1994-06-28 | Alza Corporation | Osmotic dosage system for delivering a formulation comprising liquid carrier and drug |
US5252338A (en) * | 1991-06-27 | 1993-10-12 | Alza Corporation | Therapy delayed |
US5190765A (en) * | 1991-06-27 | 1993-03-02 | Alza Corporation | Therapy delayed |
EP0656779B1 (en) * | 1992-08-28 | 2000-04-12 | Pharmos Corporation | Submicron emulsions as ocular drug delivery vehicles |
US6113921A (en) * | 1993-03-23 | 2000-09-05 | Pharmos Corp. | Topical and transdermal delivery system utilizing submicron oil spheres |
ZA953078B (en) * | 1994-04-28 | 1996-01-05 | Alza Corp | Effective therapy for epilepsies |
US5633011A (en) * | 1994-08-04 | 1997-05-27 | Alza Corporation | Progesterone replacement therapy |
US5578642A (en) * | 1994-08-17 | 1996-11-26 | Henkel Corporation | Self-emulsifying and/or emollient agents |
US5614578A (en) * | 1994-10-28 | 1997-03-25 | Alza Corporation | Injection-molded dosage form |
AU692255B2 (en) * | 1995-04-24 | 1998-06-04 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Self-emulsifiable formulation producing an oil-in-water emulsion |
US6245349B1 (en) * | 1996-02-23 | 2001-06-12 | éLAN CORPORATION PLC | Drug delivery compositions suitable for intravenous injection |
AU724635B2 (en) * | 1997-07-01 | 2000-09-28 | Pfizer Products Inc. | Gelatine encapsulated solution dosage forms of sertraline |
JP4761093B2 (ja) * | 1997-12-10 | 2011-08-31 | シクロスポリン セラポイティクス リミテッド | オメガ−3脂肪酸油を含む医薬組成物 |
US6245357B1 (en) * | 1998-03-06 | 2001-06-12 | Alza Corporation | Extended release dosage form |
US6183466B1 (en) * | 1998-08-21 | 2001-02-06 | Alza Corporation | Dosage form comprising a capsule |
US6551613B1 (en) * | 1998-09-08 | 2003-04-22 | Alza Corporation | Dosage form comprising therapeutic formulation |
US6174547B1 (en) * | 1999-07-14 | 2001-01-16 | Alza Corporation | Dosage form comprising liquid formulation |
US6221391B1 (en) * | 1998-11-23 | 2001-04-24 | Accucaps Industries Limited | Self-emulsifying ibuprofen solution and soft gelatin capsule for use therewith |
IL143580A0 (en) * | 1998-12-11 | 2002-04-21 | Pharmasolutions Inc | Pharmaceutical compositions containing lipophilic drugs and methods for the preparation thereof |
CN1161101C (zh) * | 1998-12-17 | 2004-08-11 | 阿尔扎有限公司 | 用多层包衣将填充液体的明胶胶囊转变成控制释放的系统 |
US6342249B1 (en) * | 1998-12-23 | 2002-01-29 | Alza Corporation | Controlled release liquid active agent formulation dosage forms |
US6057289A (en) * | 1999-04-30 | 2000-05-02 | Pharmasolutions, Inc. | Pharmaceutical composition comprising cyclosporin in association with a carrier in a self-emulsifying drug delivery system |
AU7709901A (en) * | 2000-07-24 | 2002-02-05 | Upjohn Co | Self-emulsifying drug delivery systems for extremely water-insoluble, lipophilicdrugs |
ATE370744T1 (de) * | 2000-09-18 | 2007-09-15 | Rpg Life Sciences Ltd | Selbstemulgierende formulierung mit erhöhter bioverfügbarkeit und immunsupprimierender wirkung |
WO2003053400A1 (en) * | 2001-12-19 | 2003-07-03 | Alza Corporation | Formulation & dosage form for the controlled delivery of therapeutic agents |
-
2003
- 2003-10-31 AU AU2003291667A patent/AU2003291667A1/en not_active Abandoned
- 2003-10-31 UY UY28057A patent/UY28057A1/es unknown
- 2003-10-31 US US10/698,894 patent/US20040142040A1/en not_active Abandoned
- 2003-10-31 WO PCT/US2003/034703 patent/WO2004041246A1/en active Application Filing
- 2003-10-31 TW TW092130379A patent/TW200423968A/zh unknown
- 2003-10-31 JP JP2004550348A patent/JP2006507309A/ja not_active Withdrawn
- 2003-10-31 EP EP03768556A patent/EP1556000A1/en not_active Withdrawn
- 2003-10-31 KR KR1020057007599A patent/KR20050083875A/ko not_active Application Discontinuation
- 2003-10-31 AR ARP030104008A patent/AR041745A1/es not_active Application Discontinuation
- 2003-10-31 CN CNA200380106667XA patent/CN1728982A/zh active Pending
- 2003-10-31 CA CA002504031A patent/CA2504031A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2004041246A1 (en) | 2004-05-21 |
TW200423968A (en) | 2004-11-16 |
KR20050083875A (ko) | 2005-08-26 |
CN1728982A (zh) | 2006-02-01 |
AR041745A1 (es) | 2005-05-26 |
JP2006507309A (ja) | 2006-03-02 |
AU2003291667A1 (en) | 2004-06-07 |
CA2504031A1 (en) | 2004-05-21 |
US20040142040A1 (en) | 2004-07-22 |
EP1556000A1 (en) | 2005-07-27 |
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