ATE370744T1 - Selbstemulgierende formulierung mit erhöhter bioverfügbarkeit und immunsupprimierender wirkung - Google Patents

Selbstemulgierende formulierung mit erhöhter bioverfügbarkeit und immunsupprimierender wirkung

Info

Publication number
ATE370744T1
ATE370744T1 AT00988993T AT00988993T ATE370744T1 AT E370744 T1 ATE370744 T1 AT E370744T1 AT 00988993 T AT00988993 T AT 00988993T AT 00988993 T AT00988993 T AT 00988993T AT E370744 T1 ATE370744 T1 AT E370744T1
Authority
AT
Austria
Prior art keywords
formulation
agent
immunosuppression
labrasol
preservative
Prior art date
Application number
AT00988993T
Other languages
English (en)
Inventor
Saibal Chakravorty
Prasad Bharti
Original Assignee
Rpg Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rpg Life Sciences Ltd filed Critical Rpg Life Sciences Ltd
Application granted granted Critical
Publication of ATE370744T1 publication Critical patent/ATE370744T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Transplantation (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT00988993T 2000-09-18 2000-09-18 Selbstemulgierende formulierung mit erhöhter bioverfügbarkeit und immunsupprimierender wirkung ATE370744T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2000/000091 WO2002022158A1 (en) 2000-09-18 2000-09-18 Selfemulsifiable formulation having enhanced bioabsorption and immunosuppression activities

Publications (1)

Publication Number Publication Date
ATE370744T1 true ATE370744T1 (de) 2007-09-15

Family

ID=11076272

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00988993T ATE370744T1 (de) 2000-09-18 2000-09-18 Selbstemulgierende formulierung mit erhöhter bioverfügbarkeit und immunsupprimierender wirkung

Country Status (12)

Country Link
US (1) US7056530B1 (de)
EP (1) EP1333851B1 (de)
AT (1) ATE370744T1 (de)
AU (2) AU2545901A (de)
BR (1) BR0013813A (de)
CA (1) CA2422580C (de)
DE (1) DE60036137T2 (de)
ES (1) ES2292496T3 (de)
MX (1) MXPA02004900A (de)
PT (1) PT1333851E (de)
SI (1) SI1333851T1 (de)
WO (1) WO2002022158A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY28057A1 (es) * 2002-10-31 2003-12-31 Alza Corp Formulacion y forma de dosificacion que provee mayor biodisponibilidad de los farmacos hidrófobos
GB0308732D0 (en) * 2003-04-15 2003-05-21 Axcess Ltd Absorption enhancers
GB0308734D0 (en) 2003-04-15 2003-05-21 Axcess Ltd Uptake of macromolecules
GB0603252D0 (en) 2006-02-17 2006-03-29 Axcess Ltd Dissolution aids for oral peptide delivery
US20130266615A1 (en) * 2012-04-10 2013-10-10 Bin Wu Non-immunogenic delivery vehicle for beta-, gamma-, and delta-tocopherols and methods of using and making same
CN114010597B (zh) * 2021-11-25 2023-05-16 广州白云山汉方现代药业有限公司 一种特殊油脂比例的棓丙酯脂肪乳注射液及其制备方法
CN114246827B (zh) * 2022-01-04 2023-04-11 中山大学 一种鱼油微乳制剂及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2870062A (en) * 1956-04-27 1959-01-20 Scherer Corp R P Gelatin composition for capsules
SE445174B (sv) 1978-03-07 1986-06-09 Sandoz Ag Farmaceutisk komposition innehallande en cyklosporin och en berarsubstans
KR0148748B1 (ko) 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
FR2705568B1 (fr) * 1993-05-27 1995-08-18 Carilene Laboratoires Utilisation de lipides peroxydés pour la préparation d'une composition pharmaceutique destinées au traitement par application locale des télangiectasies.
PT649651E (pt) * 1993-09-28 2001-03-30 Scherer Gmbh R P Preparacao de capsulas de gelatina macia
IL115742A (en) * 1994-10-26 2000-06-01 Novartis Ag Pharmaceutical compositions comprising a difficultly soluble active agent a hydrophilic phase a lipophilic phase and a surfactant
KR0167613B1 (ko) 1994-12-28 1999-01-15 한스 루돌프 하우스, 니콜 케르커 사이클로스포린-함유 연질캅셀제 조성물
US5858401A (en) * 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
EP1413297B1 (de) 1996-06-19 2008-04-23 Novartis AG Cyclosporin enthaltende Präparate
ATE497384T1 (de) * 1997-12-10 2011-02-15 Cyclosporine Therapeutics Ltd Omega-3 fettsäure enthaltende pharmazeutische zusammensetzungen
DK0982035T3 (da) 1998-08-18 2004-06-28 Panacea Biotec Ltd Cyclosporinpræparater
US6267985B1 (en) * 1999-06-30 2001-07-31 Lipocine Inc. Clear oil-containing pharmaceutical compositions

Also Published As

Publication number Publication date
AU2545901A (en) 2002-03-26
WO2002022158A1 (en) 2002-03-21
AU2001225459B2 (en) 2005-12-22
AU2001225459C1 (en) 2002-03-26
CA2422580C (en) 2011-05-17
US7056530B1 (en) 2006-06-06
DE60036137D1 (de) 2007-10-04
SI1333851T1 (sl) 2008-02-29
BR0013813A (pt) 2002-04-30
EP1333851A1 (de) 2003-08-13
ES2292496T3 (es) 2008-03-16
PT1333851E (pt) 2007-11-26
CA2422580A1 (en) 2002-03-21
EP1333851B1 (de) 2007-08-22
DE60036137T2 (de) 2008-05-15
MXPA02004900A (es) 2003-10-24

Similar Documents

Publication Publication Date Title
US11103454B2 (en) Wax foamable vehicle and pharmaceutical compositions thereof
US9682021B2 (en) Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US7820145B2 (en) Oleaginous pharmaceutical and cosmetic foam
MX9204379A (es) Microemulsiones de agua en aceite auto-emulsificables, estables, farmaceuticamente aceptables.
AP2000001943A0 (en) Orally administrable immediate-release and prolonged-release galenic form comprising an absorption-promoting agent and use of this absorption-promoting agent.
US20090130029A1 (en) Glycerol ethers vehicle and pharmaceutical compositions thereof
CA2395678A1 (en) Antimicrobial compositions and methods of use
KR20060113657A (ko) 침투성 약제용 거품제
US5853740A (en) Delivery system for pharmaceutical agents encapsulated with oils
ATE370744T1 (de) Selbstemulgierende formulierung mit erhöhter bioverfügbarkeit und immunsupprimierender wirkung
JP2016512828A (ja) ラセカドトリル脂質組成物
AU2002356421B2 (en) Dexibuprofen-containing soft gelatin capsules and process for preparing the same
RU2008105323A (ru) Консервирующая композиция для офтальмологического применения
ZA200507018B (en) Oleaginous pharmaceutical and cosmetic foam
CZ302649B6 (cs) Farmaceutická formulace zahrnující cyklosporin a její použití
Subramanian et al. Topical delivery of celecoxib using microemulsion
ES2215101T3 (es) Formulaciones farmaceuticas que contienen productos activos antiinflamatorios, y su empleo.
EP2343038B1 (de) Dermatologische Zubereitugen enthaltend eine Kombination von peroxydierten Fetten und Zink und Verwendung davon in der Behandlung von unter anderem Herpes.
WO2013182688A1 (en) A topical gel composition comprising an ingenol derivative and a solvent mixture
ES2405782T3 (es) Composición de microemulsión oral que comprende bifenildicarboxilato de dimetilo y silibina
CA3148675A1 (en) Solvent delivery system for topical delivery of active agents
ZA200104828B (en) Cyclosporin solution.
Bhatpahri et al. Cutaneous Drug Delivery Potential of Topical Microemulsion Formulations
KR20070032272A (ko) 유성 약제용 및 화장료용 거품제
WO2000048570A1 (fr) Composition pharmaceutique pour administration transmucosale balanique d'alfuzosine

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1333851

Country of ref document: EP