ZA792729B - Novel aminothiazoles - Google Patents

Novel aminothiazoles

Info

Publication number
ZA792729B
ZA792729B ZA792729A ZA792729A ZA792729B ZA 792729 B ZA792729 B ZA 792729B ZA 792729 A ZA792729 A ZA 792729A ZA 792729 A ZA792729 A ZA 792729A ZA 792729 B ZA792729 B ZA 792729B
Authority
ZA
South Africa
Prior art keywords
aminothiazoles
novel
novel aminothiazoles
Prior art date
Application number
ZA792729A
Other languages
English (en)
Inventor
J Lombardino
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA792729B publication Critical patent/ZA792729B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/42Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16BDEVICES FOR FASTENING OR SECURING CONSTRUCTIONAL ELEMENTS OR MACHINE PARTS TOGETHER, e.g. NAILS, BOLTS, CIRCLIPS, CLAMPS, CLIPS OR WEDGES; JOINTS OR JOINTING
    • F16B15/00Nails; Staples
    • F16B15/0023Nail plates
    • F16B2015/0076Nail plates with provisions for additional fastening means, e.g. hooks, holes for separate screws or nails, adhesive

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA792729A 1978-06-02 1979-06-01 Novel aminothiazoles ZA792729B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US91183078A 1978-06-02 1978-06-02

Publications (1)

Publication Number Publication Date
ZA792729B true ZA792729B (en) 1981-03-25

Family

ID=25430923

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA792729A ZA792729B (en) 1978-06-02 1979-06-01 Novel aminothiazoles

Country Status (36)

Country Link
JP (1) JPS5936988B2 (nl)
AR (1) AR226285A1 (nl)
AT (1) AT373248B (nl)
AU (1) AU511242B2 (nl)
BE (1) BE876732A (nl)
CA (1) CA1117949A (nl)
CH (1) CH639653A5 (nl)
CS (1) CS216927B2 (nl)
DD (1) DD144055A5 (nl)
DE (1) DE2922523C2 (nl)
DK (1) DK150068C (nl)
EG (1) EG14354A (nl)
ES (1) ES481220A1 (nl)
FI (1) FI68820C (nl)
FR (1) FR2427333A1 (nl)
GB (1) GB2022085B (nl)
GR (1) GR73142B (nl)
HK (1) HK66487A (nl)
HU (1) HU180045B (nl)
IE (1) IE48426B1 (nl)
IL (1) IL57450A (nl)
IT (1) IT1121238B (nl)
KE (1) KE3459A (nl)
LU (1) LU81349A1 (nl)
MY (1) MY8500318A (nl)
NL (1) NL178421C (nl)
NO (1) NO150760C (nl)
NZ (1) NZ190623A (nl)
PH (1) PH17020A (nl)
PL (1) PL117515B1 (nl)
PT (1) PT69718A (nl)
SE (1) SE438333B (nl)
SG (1) SG56184G (nl)
SU (1) SU843746A3 (nl)
YU (1) YU40997B (nl)
ZA (1) ZA792729B (nl)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57501565A (nl) * 1980-10-24 1982-09-02
JPS57136579A (en) * 1981-01-21 1982-08-23 Mitsui Toatsu Chem Inc Thiazolylurea derivative, its preparation, and pharmaceutical composition containing the same
EP0068033B1 (en) * 1981-01-08 1985-07-10 Mitsui Toatsu Kagaku Kabushiki Kaisha N-(4-phenyl-2-thiazolyl)carbamate derivatives, process for their preparation, and medicinal composition containing same
JPS57116067A (en) * 1981-01-12 1982-07-19 Sankyo Kagaku Kk Novel 8-quinolinesulfonyl derivative, its synthesis and use
US4501750A (en) * 1981-01-13 1985-02-26 Mitsui Toatsu Kaguku Kabushiki Kaisha Thiazole compounds, a process for preparing same and a pharmaceutical composition containing the thiazole compounds
WO1982002386A1 (en) * 1981-01-13 1982-07-22 Sakano Isao Aminothiazole derivatives,process for their preparation,and medicinal composition containing same
JPS57154175A (en) * 1981-03-16 1982-09-22 Mitsui Toatsu Chem Inc 2-thiazoleamine derivative, its preparation, and drug composition comprising it
DE3227329A1 (de) * 1982-07-22 1984-01-26 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von 2-n,n-disubstituierten aminothiazolen
WO1986003203A1 (en) * 1984-11-22 1986-06-05 Yoshitomi Pharmaceutical Industries, Ltd. Thienylthiazole derivatives
FR2581063B1 (fr) * 1985-04-30 1987-07-17 Chauvin Blache Lab Amino-2 thiazoles n-substitues, leur procede de preparation et leur application en therapeutique
JPS63152368A (ja) * 1986-06-03 1988-06-24 Sumitomo Pharmaceut Co Ltd 新規なアミノアゾ−ル誘導体およびその酸付加塩
JPH075579B2 (ja) * 1986-09-01 1995-01-25 吉富製薬株式会社 アミノチアゾ−ル化合物
JPH0753666B2 (ja) * 1987-09-14 1995-06-07 久光製薬株式会社 置換ジフェニルチアゾール誘導体からなる抗炎症剤
ATE159622T1 (de) * 1989-08-10 1997-11-15 Commw Scient Ind Res Org Verfahren zur herstellung von einer elektrosuspension von mikropartikeln
DE69132293D1 (de) * 1991-03-07 2000-08-10 Hisamitsu Pharmaceutical Co Diphenylthiazolderivate mit antiinflammatorischer aktivität
FR2692893B1 (fr) * 1992-06-24 1994-09-02 Sanofi Elf Dérivés alkylamino ramifiés du thiazole, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
CA2195847A1 (en) * 1994-07-27 1996-02-08 John J. Talley Substituted thiazoles for the treatment of inflammation
FR2754258B1 (fr) 1996-10-08 1998-12-31 Sanofi Sa Derives d'aminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant
US7105550B2 (en) * 2000-03-01 2006-09-12 Christopher Love 2,4-disubstituted thiazolyl derivatives
EP1423113A4 (en) * 2001-08-13 2007-04-18 Phenex Pharmaceuticals Ag NR1H4 NUCLEAR RECEPTOR BINDING COMPOUNDS
WO2003027096A1 (en) * 2001-09-26 2003-04-03 Bayer Pharmaceuticals Corporation Substituted 3-pyridyl imidazoles as c17,20 lyase inhibitors
PT1471054E (pt) 2002-01-11 2009-09-23 Daiichi Sankyo Co Ltd Derivado de aminoálcool ou derivado de ácido fosfónico e composição medicinal que os contém
EP1555264A1 (en) * 2004-01-15 2005-07-20 Sireen AG Five-membered heterocyclic compounds as inhibitors of SRC family protein kinase.
KR20110136901A (ko) 2004-02-24 2011-12-21 상꾜 가부시키가이샤 아미노 알코올 화합물
KR20080019213A (ko) 2005-05-09 2008-03-03 아칠리온 파르마세우티칼스 인코포레이티드 티아졸 화합물 및 그 사용방법
ES2389062T3 (es) 2006-01-18 2012-10-22 Amgen, Inc Compuestos de tiazol como inhibidores de proteína cinasa B (PKB)
AU2008276521B2 (en) 2007-07-17 2011-11-03 Amgen Inc. Heterocyclic modulators of PKB
AU2008276512A1 (en) 2007-07-17 2009-01-22 Amgen Inc. Thiadiazole modulators of PKB
WO2012170951A2 (en) * 2011-06-10 2012-12-13 Calcimedica, Inc. Compounds that modulate intracellular calcium
US20120316182A1 (en) 2011-06-10 2012-12-13 Calcimedica, Inc. Compounds that modulate intracellular calcium
US9856240B2 (en) 2011-10-19 2018-01-02 Calcimedica, Inc. Compounds that modulate intracellular calcium
CN110590785B (zh) * 2019-09-23 2021-02-02 武汉大学 一种氨基噻唑类化合物及其制备方法与抗肠道病毒71型的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3458526A (en) * 1966-09-26 1969-07-29 Upjohn Co Certain 2-amino-4,5-bis(p-methoxyphenyl)thiazoles

Also Published As

Publication number Publication date
FI68820C (fi) 1985-11-11
HK66487A (en) 1987-09-25
FI68820B (fi) 1985-07-31
IT1121238B (it) 1986-03-26
GB2022085B (en) 1983-01-12
PL117515B1 (en) 1981-08-31
PT69718A (en) 1979-07-01
HU180045B (en) 1983-01-28
DD144055A5 (de) 1980-09-24
PL216030A1 (nl) 1980-03-10
YU128879A (en) 1982-10-31
IE791069L (en) 1979-12-02
EG14354A (en) 1984-06-30
GR73142B (nl) 1984-02-09
IT7923228A0 (it) 1979-06-01
NO791831L (no) 1979-12-04
NZ190623A (en) 1984-07-06
DK150068B (da) 1986-12-01
IL57450A0 (en) 1979-09-30
MY8500318A (en) 1985-12-31
NO150760B (no) 1984-09-03
CS216927B2 (en) 1982-12-31
FR2427333B1 (nl) 1983-05-20
PH17020A (en) 1984-05-11
NO150760C (no) 1984-12-12
SE7904798L (sv) 1979-12-03
BE876732A (fr) 1979-12-03
AT373248B (de) 1983-12-27
NL7904337A (nl) 1979-12-04
FI791754A (fi) 1979-11-26
DK177679A (da) 1979-12-03
JPS5936988B2 (ja) 1984-09-06
CH639653A5 (fr) 1983-11-30
ES481220A1 (es) 1980-09-01
DE2922523C2 (de) 1982-10-21
DE2922523A1 (de) 1979-12-06
FR2427333A1 (fr) 1979-12-28
ATA401679A (de) 1983-05-15
AU511242B2 (en) 1980-08-07
IE48426B1 (en) 1985-01-23
CA1117949A (en) 1982-02-09
IL57450A (en) 1982-11-30
NL178421C (nl) 1986-03-17
DK150068C (da) 1987-06-29
YU40997B (en) 1986-10-31
GB2022085A (en) 1979-12-12
SE438333B (sv) 1985-04-15
SU843746A3 (ru) 1981-06-30
AR226285A1 (es) 1982-06-30
SG56184G (en) 1985-03-08
LU81349A1 (fr) 1979-12-07
NL178421B (nl) 1985-10-16
JPS54160369A (en) 1979-12-19
KE3459A (en) 1984-10-12
AU4763479A (en) 1979-12-06

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