ZA200804521B - Methods and compounds for preparing CC-1065 analogs - Google Patents

Methods and compounds for preparing CC-1065 analogs

Info

Publication number
ZA200804521B
ZA200804521B ZA200804521A ZA200804521A ZA200804521B ZA 200804521 B ZA200804521 B ZA 200804521B ZA 200804521 A ZA200804521 A ZA 200804521A ZA 200804521 A ZA200804521 A ZA 200804521A ZA 200804521 B ZA200804521 B ZA 200804521B
Authority
ZA
South Africa
Prior art keywords
analogs
preparing
compounds
methods
alkyl
Prior art date
Application number
ZA200804521A
Other languages
English (en)
Inventor
Gangwar Sanjeev
Zhang Qian
Original Assignee
Medarex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medarex Inc filed Critical Medarex Inc
Publication of ZA200804521B publication Critical patent/ZA200804521B/xx

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/60Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA200804521A 2005-10-26 2008-05-23 Methods and compounds for preparing CC-1065 analogs ZA200804521B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73080405P 2005-10-26 2005-10-26

Publications (1)

Publication Number Publication Date
ZA200804521B true ZA200804521B (en) 2009-04-29

Family

ID=37766648

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200804521A ZA200804521B (en) 2005-10-26 2008-05-23 Methods and compounds for preparing CC-1065 analogs

Country Status (23)

Country Link
US (1) US7847105B2 (xx)
EP (1) EP1940789B1 (xx)
JP (1) JP5116686B2 (xx)
KR (1) KR20080068084A (xx)
CN (1) CN101365679B (xx)
AT (1) ATE534629T1 (xx)
AU (1) AU2006305842B2 (xx)
BR (1) BRPI0619331A2 (xx)
CA (1) CA2627046C (xx)
CY (1) CY1112533T1 (xx)
DK (1) DK1940789T3 (xx)
EA (1) EA015324B1 (xx)
ES (1) ES2375843T3 (xx)
HK (1) HK1118549A1 (xx)
HR (1) HRP20120058T1 (xx)
IL (1) IL190971A (xx)
NO (1) NO20082243L (xx)
PL (1) PL1940789T3 (xx)
PT (1) PT1940789E (xx)
RS (1) RS52100B (xx)
SI (1) SI1940789T1 (xx)
WO (1) WO2007051081A1 (xx)
ZA (1) ZA200804521B (xx)

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