ZA200107999B - Formation and anion-exchange of crystalline echinocandin ammonium salts. - Google Patents

Formation and anion-exchange of crystalline echinocandin ammonium salts.

Info

Publication number
ZA200107999B
ZA200107999B ZA200107999A ZA200107999A ZA200107999B ZA 200107999 B ZA200107999 B ZA 200107999B ZA 200107999 A ZA200107999 A ZA 200107999A ZA 200107999 A ZA200107999 A ZA 200107999A ZA 200107999 B ZA200107999 B ZA 200107999B
Authority
ZA
South Africa
Prior art keywords
anion
exchange
formation
salt
ammonium salts
Prior art date
Application number
ZA200107999A
Other languages
English (en)
Inventor
Brian Weston Dadler
Michael Anthony Dotlich
Neil John Kallman
Samuel Dean Larsen
Sharon Van Den Berghe Snorek
Jeffrey Thomas Vicenzi
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA200107999B publication Critical patent/ZA200107999B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/84—Manufacture, treatment, or detection of nanostructure
    • Y10S977/895—Manufacture, treatment, or detection of nanostructure having step or means utilizing chemical property
    • Y10S977/896—Chemical synthesis, e.g. chemical bonding or breaking
    • Y10S977/898—Enzymatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
ZA200107999A 1999-03-03 2001-09-28 Formation and anion-exchange of crystalline echinocandin ammonium salts. ZA200107999B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12307399P 1999-03-03 1999-03-03

Publications (1)

Publication Number Publication Date
ZA200107999B true ZA200107999B (en) 2003-06-25

Family

ID=22406562

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200107999A ZA200107999B (en) 1999-03-03 2001-09-28 Formation and anion-exchange of crystalline echinocandin ammonium salts.

Country Status (18)

Country Link
US (1) US6590073B2 (enExample)
EP (1) EP1155034B1 (enExample)
JP (1) JP4063497B2 (enExample)
KR (1) KR20020002476A (enExample)
CN (1) CN1351610A (enExample)
AT (1) ATE338060T1 (enExample)
AU (1) AU767956B2 (enExample)
BR (1) BR0009248A (enExample)
CA (1) CA2362826A1 (enExample)
CY (1) CY1105777T1 (enExample)
DE (1) DE60030415T2 (enExample)
DK (1) DK1155034T3 (enExample)
ES (1) ES2270819T3 (enExample)
HK (1) HK1040087A1 (enExample)
IL (1) IL145186A0 (enExample)
PT (1) PT1155034E (enExample)
WO (1) WO2000052036A1 (enExample)
ZA (1) ZA200107999B (enExample)

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US6743777B1 (en) * 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
CN1337968A (zh) 1998-12-09 2002-02-27 伊莱利利公司 蓝刺菌素环肽化合物的纯化
DK1155034T3 (da) 1999-03-03 2007-01-08 Lilly Co Eli Dannelse og anionbytning af indre krystallinske echinocandin B-ammoniumsalte
JP2002538097A (ja) 1999-03-03 2002-11-12 イーライ リリー アンド カンパニー 薬学的経口ｅｃｂ処方物および組成物の作製方法
CN100335122C (zh) * 1999-03-03 2007-09-05 伊莱利利公司 含有成胶束表面活性剂的棘白菌素药物制剂
KR20020003864A (ko) 1999-03-03 2002-01-15 피터 지. 스트링거 에키노칸딘/탄수화물 착물
US6991800B2 (en) 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
TW200826957A (en) * 2006-10-16 2008-07-01 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Purification processes for echinocandin-type compounds
EP2062909A1 (en) * 2007-11-21 2009-05-27 SOLVAY (Société Anonyme) Peptide production and purification process
US9394340B2 (en) 2009-03-24 2016-07-19 Cadila Healthcare Limited Purification process for lipopeptides
WO2010108637A1 (en) * 2009-03-27 2010-09-30 Axellia Pharmaceuticals Aps Crystalline compound
CN102464704B (zh) * 2010-11-05 2013-12-11 上海医药工业研究院 一种化合物及其制备方法和用途
CN102485879A (zh) * 2010-12-03 2012-06-06 上海医药工业研究院 一种用于生产wf11899a的发酵培养基
CN102295686A (zh) * 2011-09-09 2011-12-28 杭州华东医药集团生物工程研究所有限公司 一种纽莫康定b0的提取纯化方法
CN102659930B (zh) * 2012-03-30 2014-04-23 上海天伟生物制药有限公司 一种高纯度环肽类物质的晶体及其制备方法和用途
CN102627688B (zh) * 2012-03-30 2014-12-31 上海天伟生物制药有限公司 一种高纯度环肽化合物及其制备方法和用途
CN102627689B (zh) * 2012-03-30 2014-08-06 上海天伟生物制药有限公司 一种环肽类化合物的水合物及其制备方法和用途
CN105669839B (zh) * 2014-12-05 2019-08-13 重庆乾泰生物医药有限公司 一种棘白菌素b母核或其盐的水合物及制备方法和用途
CN105669840B (zh) * 2014-12-05 2019-06-04 重庆乾泰生物医药有限公司 一种高纯度棘白菌素b母核盐酸盐的晶体及其制备方法
US12060439B2 (en) 2018-10-25 2024-08-13 Napp Pharmaceutical Group Limited Polymorph of echinocandin antifungal agent

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EP0460882B1 (en) 1990-06-07 1996-07-24 Eli Lilly And Company Lipopeptide deacylase
FI912873L (fi) 1990-06-18 1991-12-19 Fujisawa Pharmaceutical Co Ny polypeptidfoerening och foerfarande foer dess framstaellning.
US5198421A (en) 1991-04-26 1993-03-30 Merck & Co., Inc. Phosphorylated cyclic lipopeptide
IL105048A (en) 1992-03-19 2001-06-14 Eli Lilly And Company U S Cyclic peptide antifungal agents and process for preparation thereof
US5965525A (en) 1992-03-19 1999-10-12 Eli Lilly And Company Cyclic peptide antifungal agents
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US5646111A (en) 1995-04-07 1997-07-08 Eli Lilly And Company Cyclic peptide antifungal Agents
US5652213A (en) 1995-05-26 1997-07-29 Eli Lilly And Company Cyclic peptide antifungal agents
US5618787A (en) 1995-05-26 1997-04-08 Eli Lilly And Company Cyclic peptide antifungal agents
US5786325A (en) 1995-05-26 1998-07-28 Eli Lilly And Company Cyclic peptide antifungal agents and methods of making and using
US5629290A (en) 1995-05-26 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
US5629289A (en) 1995-07-25 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
JP2001503015A (ja) * 1996-02-01 2001-03-06 イーライ・リリー・アンド・カンパニー 環状ペプチド抗真菌剤
JPH1036284A (ja) * 1996-07-24 1998-02-10 Sumitomo Pharmaceut Co Ltd プロテアソーム阻害剤
AU8687798A (en) 1997-08-04 1999-02-22 Eli Lilly And Company Cyclic peptide antifungal agents
US6232290B1 (en) * 1998-02-09 2001-05-15 Fujisawa Pharmaceutical Co., Ltd. Cyclic hexapeptides with antimicrobial activity
US6323176B1 (en) 1998-02-25 2001-11-27 Eli Lilly And Company Cyclic peptide antifungal agents
EP1107981B1 (en) 1998-08-20 2005-01-26 Eli Lilly & Company Synthesis of ring-modified cyclic peptide analogs
ATE267210T1 (de) 1998-08-28 2004-06-15 Lilly Co Eli Reversible borkomplexe von 1,2-(cis)-diol zyklischen peptiden
CN1337968A (zh) 1998-12-09 2002-02-27 伊莱利利公司 蓝刺菌素环肽化合物的纯化
JP2002535248A (ja) 1998-12-16 2002-10-22 イーライ リリー アンド カンパニー 環式ペプチド抗真菌剤
CA2354055A1 (en) 1998-12-16 2000-06-22 Eli Lilly And Company Cyclic peptide antifungal agents having a sugar substituent
DK1155034T3 (da) 1999-03-03 2007-01-08 Lilly Co Eli Dannelse og anionbytning af indre krystallinske echinocandin B-ammoniumsalte
KR20020003864A (ko) 1999-03-03 2002-01-15 피터 지. 스트링거 에키노칸딘/탄수화물 착물
JP2002538097A (ja) 1999-03-03 2002-11-12 イーライ リリー アンド カンパニー 薬学的経口ｅｃｂ処方物および組成物の作製方法
CN100335122C (zh) 1999-03-03 2007-09-05 伊莱利利公司 含有成胶束表面活性剂的棘白菌素药物制剂

Also Published As

Publication number Publication date
HK1040087A1 (zh) 2002-05-24
KR20020002476A (ko) 2002-01-09
DE60030415T2 (de) 2007-08-30
CA2362826A1 (en) 2000-09-08
US20020161176A1 (en) 2002-10-31
DK1155034T3 (da) 2007-01-08
CN1351610A (zh) 2002-05-29
JP4063497B2 (ja) 2008-03-19
WO2000052036A1 (en) 2000-09-08
BR0009248A (pt) 2001-11-20
JP2002538165A (ja) 2002-11-12
ES2270819T3 (es) 2007-04-16
ATE338060T1 (de) 2006-09-15
US6590073B2 (en) 2003-07-08
AU3718200A (en) 2000-09-21
EP1155034A1 (en) 2001-11-21
CY1105777T1 (el) 2011-02-02
AU767956B2 (en) 2003-11-27
DE60030415D1 (de) 2006-10-12
IL145186A0 (en) 2002-06-30
EP1155034B1 (en) 2006-08-30
WO2000052036A8 (en) 2001-06-21
PT1155034E (pt) 2007-01-31

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