AR005903A1 - Un proceso para la preparacion de clorhidrato en n(g)-monometil-l-arginina - Google Patents

Un proceso para la preparacion de clorhidrato en n(g)-monometil-l-arginina

Info

Publication number
AR005903A1
AR005903A1 ARP970100652A ARP970100652A AR005903A1 AR 005903 A1 AR005903 A1 AR 005903A1 AR P970100652 A ARP970100652 A AR P970100652A AR P970100652 A ARP970100652 A AR P970100652A AR 005903 A1 AR005903 A1 AR 005903A1
Authority
AR
Argentina
Prior art keywords
monomethyl
preparation
arginine
chlorhydrate
acid addition
Prior art date
Application number
ARP970100652A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of AR005903A1 publication Critical patent/AR005903A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/08Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un proceso para la preparación de clorhidrato de N(G)-monometil-L-arginina, el cual comprende la reacción de un compuesto de la fórmula (I) o una sal deadición de ácido del mismo, en donde L es un grupo saliente con L-ornitina o una sal de adiciónde ácido de la misma, en un solvente polar adecuado,seguida de acidificación hasta pH entre 4 y 5, y luego de la adición de un solvente alcohólico, se aisla el producto a partir de la mezcla de reacción,mediante cristalización.
ARP970100652A 1996-02-20 1997-02-19 Un proceso para la preparacion de clorhidrato en n(g)-monometil-l-arginina AR005903A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9603522.5A GB9603522D0 (en) 1996-02-20 1996-02-20 Chemical process

Publications (1)

Publication Number Publication Date
AR005903A1 true AR005903A1 (es) 1999-07-21

Family

ID=10789060

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP970100652A AR005903A1 (es) 1996-02-20 1997-02-19 Un proceso para la preparacion de clorhidrato en n(g)-monometil-l-arginina

Country Status (11)

Country Link
EP (1) EP0882014A1 (es)
JP (1) JP2000504738A (es)
AR (1) AR005903A1 (es)
AU (1) AU1791697A (es)
CO (1) CO4761060A1 (es)
GB (1) GB9603522D0 (es)
ID (1) ID15968A (es)
PE (1) PE43198A1 (es)
TW (1) TW370520B (es)
WO (1) WO1997030972A1 (es)
ZA (1) ZA971398B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10050900A1 (de) * 2000-10-13 2002-04-25 Degussa Verfahren zur Herstellung von 1-Guanylpyrazolsäureadditionsprodukten

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9215816D0 (en) * 1992-07-24 1992-09-09 Wellcome Found Arginine derivatives

Also Published As

Publication number Publication date
TW370520B (en) 1999-09-21
EP0882014A1 (en) 1998-12-09
GB9603522D0 (en) 1996-04-17
CO4761060A1 (es) 1999-04-27
WO1997030972A1 (en) 1997-08-28
AU1791697A (en) 1997-09-10
ZA971398B (en) 1997-08-20
JP2000504738A (ja) 2000-04-18
ID15968A (id) 1997-08-21
PE43198A1 (es) 1998-08-26

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