DE60332776D1 - Herstellung von Delta-9-Tetrahydrocannabinol - Google Patents

Herstellung von Delta-9-Tetrahydrocannabinol

Info

Publication number
DE60332776D1
DE60332776D1 DE60332776T DE60332776T DE60332776D1 DE 60332776 D1 DE60332776 D1 DE 60332776D1 DE 60332776 T DE60332776 T DE 60332776T DE 60332776 T DE60332776 T DE 60332776T DE 60332776 D1 DE60332776 D1 DE 60332776D1
Authority
DE
Germany
Prior art keywords
acid
thc
tetrahydrocannabinol
delta
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60332776T
Other languages
English (en)
Inventor
Alan Kenneth Greenwood
Derek Mchattie
Neil John Goodwin
Nicolas James Archer
Christopher Murray
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Resolution Chemicals Ltd
Original Assignee
Resolution Chemicals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0202396A external-priority patent/GB0202396D0/en
Application filed by Resolution Chemicals Ltd filed Critical Resolution Chemicals Ltd
Application granted granted Critical
Publication of DE60332776D1 publication Critical patent/DE60332776D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Psychiatry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Pyrane Compounds (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
  • Optical Integrated Circuits (AREA)
  • Steroid Compounds (AREA)
DE60332776T 2002-02-01 2003-02-03 Herstellung von Delta-9-Tetrahydrocannabinol Expired - Lifetime DE60332776D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0202396A GB0202396D0 (en) 2002-02-01 2002-02-01 Production of delta 9 tetrahydrocannabinol
GB0214022A GB0214022D0 (en) 2002-02-01 2002-06-18 Production of delta 9 tetrahydrocannabinol

Publications (1)

Publication Number Publication Date
DE60332776D1 true DE60332776D1 (de) 2010-07-08

Family

ID=27665366

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60332776T Expired - Lifetime DE60332776D1 (de) 2002-02-01 2003-02-03 Herstellung von Delta-9-Tetrahydrocannabinol
DE60321318T Expired - Lifetime DE60321318D1 (de) 2002-02-01 2003-02-03 Gewinnung von delta-9 tetrahydrocannabinol

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60321318T Expired - Lifetime DE60321318D1 (de) 2002-02-01 2003-02-03 Gewinnung von delta-9 tetrahydrocannabinol

Country Status (17)

Country Link
US (3) US7524881B2 (de)
EP (2) EP1474412B1 (de)
JP (1) JP2005526715A (de)
CN (2) CN100999513A (de)
AT (1) ATE396984T1 (de)
AU (2) AU2003205844B2 (de)
BR (1) BR0307330A (de)
CA (1) CA2474951A1 (de)
DE (2) DE60332776D1 (de)
DK (1) DK1474412T3 (de)
ES (1) ES2305437T3 (de)
NO (1) NO20043209L (de)
NZ (2) NZ552547A (de)
PT (1) PT1474412E (de)
SI (1) SI1474412T1 (de)
WO (1) WO2003064407A2 (de)
ZA (1) ZA200405938B (de)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1474412T1 (sl) * 2002-02-01 2008-10-31 Resolution Chemicals Ltd Proizvodnja delta-9 tetrahidrokanabinola
PT2311475T (pt) * 2002-08-14 2016-09-22 Gw Pharma Ltd Extração de canabinoides farmaceuticamente ativos a partir de material vegetal
GB2391865B (en) * 2002-08-14 2005-06-01 Gw Pharma Ltd Improvements in the extraction of pharmaceutically active components from plant materials
GB0222077D0 (en) 2002-09-23 2002-10-30 Gw Pharma Ltd Methods of preparing cannabinoids from plant material
GB2408978B (en) * 2002-09-23 2006-04-05 Gw Pharma Ltd Methods of preparing delta-9 tetrahydrocannabinol from plant material
TWI369203B (en) 2004-11-22 2012-08-01 Euro Celtique Sa Methods for purifying trans-(-)-△9-tetrahydrocannabinol and trans-(+)-△9-tetrahydrocannabinol
WO2006063109A2 (en) * 2004-12-09 2006-06-15 Insys Therapeutics, Inc. Room-temperature stable dronabinol formulations
TWI366460B (en) 2005-06-16 2012-06-21 Euro Celtique Sa Cannabinoid active pharmaceutical ingredient for improved dosage forms
KR20080063800A (ko) * 2005-09-29 2008-07-07 에이엠알 테크놀로지, 인크. 델타-9-테트라히드로칸나비놀의 제조 방법
CN101516333A (zh) * 2006-08-04 2009-08-26 英西斯治疗学股份有限公司 水性屈大麻酚制剂
US20080103193A1 (en) * 2006-10-26 2008-05-01 Trevor Percival Castor Methods for making compositions and compositions for treating pain and cachexia
GB0703284D0 (en) 2007-02-20 2007-03-28 Resolution Chemicals Ltd Delta 9 - tetrahydrocannabinol processing
JP2010535774A (ja) * 2007-08-06 2010-11-25 インシス セラピューティクス インコーポレイテッド 経口カンナビノイド液体製剤および治療方法
US20090042974A1 (en) * 2007-08-07 2009-02-12 Anson David Parker Compositions And Methods Relating To Extensible Transgenic Vector Assembler, Pestilence Ridder, Plus Cannabinoid Producer
GB0807915D0 (en) * 2008-05-01 2008-06-04 Resolution Chemicals Ltd Production of delta 9 tetrahydrocannabinol
US8343553B2 (en) 2011-04-18 2013-01-01 Hospodor Andrew D Essential element extractor
US9376367B2 (en) 2011-09-29 2016-06-28 The Health Concept Gmbh Cannabinoid carboxylic acids, salts of cannabinoid carboxylic acids, and the production and uses of same
US9358259B2 (en) 2012-03-20 2016-06-07 Andrew David Hospodor Recycling cannabinoid extractor
IN2014DN09507A (de) * 2012-05-03 2015-07-17 Echo Pharmaceuticals Bv
US20130337052A1 (en) * 2012-06-19 2013-12-19 Patricia Linert System and Method of Reducing Impairment of Alertness, Concentration, Motivation, and Creativity Caused by Medication
US9155767B2 (en) 2012-10-18 2015-10-13 Andrew D. Hospodor Essential element management
EP4137142A1 (de) * 2013-03-14 2023-02-22 Purple Mundo, Inc. Bioaktive konzentrate und verwendungen davon
US9199960B2 (en) * 2013-05-02 2015-12-01 Frederick R. Ferri Method and apparatus for processing herbaceous plant materials including the cannabis plant
US9380813B2 (en) 2014-02-11 2016-07-05 Timothy McCullough Drug delivery system and method
US10821240B2 (en) 2014-02-11 2020-11-03 Vapor Cartridge Technology Llc Methods and drug delivery devices using cannabis
US9220294B2 (en) 2014-02-11 2015-12-29 Timothy McCullough Methods and devices using cannabis vapors
US20170312327A1 (en) * 2014-11-17 2017-11-02 Connoisseur Holdings, Llc Extraction devices, systems, and methods
US11034639B2 (en) 2015-01-22 2021-06-15 Phytoplant Research S.L. Methods of purifying cannabinoids using liquid:liquid chromatography
US10207198B2 (en) * 2015-01-22 2019-02-19 Phytoplant Research S.L. Methods of purifying cannabinoids using liquid:liquid chromatography
ES2801005T3 (es) * 2015-01-22 2021-01-07 Phytoplant Res S L Métodos de purificar canabinoides, composiciones y kits asociados
US11040295B2 (en) 2015-02-06 2021-06-22 Joseph Francis Payack Method and apparatus for extracting plant oils using ethanol water
MA42057A (fr) * 2015-05-07 2018-03-14 Axim Biotechnologies Inc Procédé d'extraction et de purification de delta-9-tétrahydrocannabinol
US10913071B2 (en) 2016-03-09 2021-02-09 Pearson Incorporated Scalper apparatus and processing system
US10499584B2 (en) 2016-05-27 2019-12-10 New West Genetics Industrial hemp Cannabis cultivars and seeds with stable cannabinoid profiles
EP3478307A4 (de) 2016-06-29 2020-02-26 Cannscience Innovations Inc. Decarboxylierte cannabisharze, verwendungen davon und verfahren zur herstellung davon
US9908832B2 (en) * 2016-07-15 2018-03-06 S.S. Steiner, Inc. Decarboxylation of cannabidiolic acid in hemp biomass and hemp extract
US10322487B1 (en) 2016-07-15 2019-06-18 Pearson Incorporated Roller mill grinding apparatus with regenerative capability
US10239808B1 (en) 2016-12-07 2019-03-26 Canopy Holdings, LLC Cannabis extracts
US10702495B2 (en) 2017-02-20 2020-07-07 Nexien Biopharma, Inc. Method and compositions for treating dystrophies and myotonia
US10807098B1 (en) 2017-07-26 2020-10-20 Pearson Incorporated Systems and methods for step grinding
IT201700085508A1 (it) * 2017-07-26 2019-01-26 Inalco S R L Metodo per la produzione di cannabinoidi da varietà di canapa industriale
US10272360B2 (en) 2017-08-05 2019-04-30 Priya Naturals, Inc. Phytochemical extraction system and methods to extract phytochemicals from plants including plants of the family Cannabaceae sensu stricto
US10406453B2 (en) * 2017-09-29 2019-09-10 NextLeaf Solutions Ltd. Cannabinoid extraction process using brine
US10941102B2 (en) * 2017-11-29 2021-03-09 Robert Henry Wohleb Aqueous leaching method to produce microcrystalline powder
AU2019211188A1 (en) * 2018-01-29 2020-07-30 Phytoplant Research S.L. Methods of purifying cannabinoids using liquid:liquid chromatography
US11202771B2 (en) 2018-01-31 2021-12-21 Treehouse Biotech, Inc. Hemp powder
US11325133B1 (en) 2018-07-26 2022-05-10 Pearson Incorporated Systems and methods for monitoring the roll diameter and shock loads in a milling apparatus
WO2020060959A1 (en) * 2018-09-17 2020-03-26 Sorbent Technologies, Inc. Methods for removing contaminants from plant-derived pharmaceuticals
US11040932B2 (en) 2018-10-10 2021-06-22 Treehouse Biotech, Inc. Synthesis of cannabigerol
US10751722B1 (en) 2018-10-24 2020-08-25 Pearson Incorporated System for processing cannabis crop materials
WO2020150616A1 (en) * 2019-01-17 2020-07-23 Synthonics, Inc. Solid micellar compositions of cannabinoid acids
US10785906B2 (en) 2019-02-19 2020-09-29 Pearson Incorporated Plant processing system
JP2022533514A (ja) * 2019-03-24 2022-07-25 オメガ ライフ サイエンス リミテッド 電子タバコ
WO2020210119A1 (en) 2019-04-11 2020-10-15 Mantrose-Haeuser Co., Inc. Cannabis delivery with protective glaze coating
AU2020262269B2 (en) 2019-04-23 2024-03-28 Soma Oil Llc Cannabis processing systems and methods
EP3750528A1 (de) 2019-06-11 2020-12-16 Nexien Biopharma, Inc. Zusammensetzungen zur behandlung von dystrophien und myotonie
US11497249B2 (en) 2019-09-16 2022-11-15 Vapor Cartridge Technology Llc Drug delivery system with stackable substrates
US10757860B1 (en) 2019-10-31 2020-09-01 Hemp Processing Solutions, LLC Stripper apparatus crop harvesting system
US10933424B1 (en) 2019-12-11 2021-03-02 Pearson Incorporated Grinding roll improvements
CN111039760A (zh) * 2019-12-16 2020-04-21 福建省中科生物股份有限公司 一种制备酚类化合物的方法
US11351476B2 (en) * 2020-01-07 2022-06-07 Agrify Corporation Method for chemical separation of cannabinoids
WO2021248235A1 (en) * 2020-06-09 2021-12-16 Protonify Corporation Process for isolation and purification of thca from cannabis
CA3191486A1 (en) 2020-09-04 2022-03-10 Giovanni VENTURINI DEL GRECO Thc-free cannabinoid concentrate, method of obtaining the same and use thereof
US11242328B1 (en) * 2021-02-25 2022-02-08 Acid Neutral Alkaline Laboratory Heterogeneous catalyst and method for preparation of aromatic tricyclic pyrans
US11352337B1 (en) * 2021-06-02 2022-06-07 Acid Neutral Alkaline Laboratory Zeolite catalyst and method for preparation of aromatic tricyclic pyrans
CN115260005B (zh) * 2022-08-30 2024-01-30 晨光生物科技集团股份有限公司 一种纯化提取大麻二酚的方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342971A (en) * 1992-12-29 1994-08-30 The Australian National University Process for the preparation of dibenzo[b,d]pyrans
WO1996034534A1 (en) 1995-05-05 1996-11-07 Hauser Inc. High purity carnosic acid from rosemary and sage extracts by ph-controlled precipitation
GB9726916D0 (en) * 1997-12-19 1998-02-18 Danbiosyst Uk Nasal formulation
US6730519B2 (en) * 1998-10-26 2004-05-04 The University Of Mississippi Method of preparing delta-9-tetrahydrocannabinol
US6365416B1 (en) * 1998-10-26 2002-04-02 The University Of Mississippi Method of preparing delta-9-tetrahydrocannabinol
SI1474412T1 (sl) * 2002-02-01 2008-10-31 Resolution Chemicals Ltd Proizvodnja delta-9 tetrahidrokanabinola

Also Published As

Publication number Publication date
BR0307330A (pt) 2004-12-07
PT1474412E (pt) 2008-07-04
CA2474951A1 (en) 2003-08-07
DK1474412T3 (da) 2008-09-01
NZ534430A (en) 2007-09-28
WO2003064407A3 (en) 2003-10-16
CN100999513A (zh) 2007-07-18
EP1474412A2 (de) 2004-11-10
EP1803717B1 (de) 2010-05-26
NZ552547A (en) 2008-03-28
EP1474412B1 (de) 2008-05-28
ZA200405938B (de) 2006-05-31
US20090253783A1 (en) 2009-10-08
AU2006252300B2 (en) 2009-02-12
DE60321318D1 (de) 2008-07-10
AU2003205844B2 (en) 2006-10-12
US20050171361A1 (en) 2005-08-04
EP1803717A2 (de) 2007-07-04
AU2006252300A1 (en) 2007-01-25
US7592468B2 (en) 2009-09-22
CN1642934A (zh) 2005-07-20
SI1474412T1 (sl) 2008-10-31
EP1803717A3 (de) 2007-07-11
WO2003064407A2 (en) 2003-08-07
ATE396984T1 (de) 2008-06-15
US7524881B2 (en) 2009-04-28
US20050049298A1 (en) 2005-03-03
ES2305437T3 (es) 2008-11-01
JP2005526715A (ja) 2005-09-08
NO20043209L (no) 2004-10-28

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