IT201700085508A1 - Metodo per la produzione di cannabinoidi da varietà di canapa industriale - Google Patents

Metodo per la produzione di cannabinoidi da varietà di canapa industriale

Info

Publication number
IT201700085508A1
IT201700085508A1 IT102017000085508A IT201700085508A IT201700085508A1 IT 201700085508 A1 IT201700085508 A1 IT 201700085508A1 IT 102017000085508 A IT102017000085508 A IT 102017000085508A IT 201700085508 A IT201700085508 A IT 201700085508A IT 201700085508 A1 IT201700085508 A1 IT 201700085508A1
Authority
IT
Italy
Prior art keywords
cannabinoids
variety
production
industrial hemp
hemp
Prior art date
Application number
IT102017000085508A
Other languages
English (en)
Inventor
Giovanni Cipolletti
Luana Vagnoli
Marina Matulli
Barbara Februari
Jacopo Chini
Original Assignee
Inalco S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inalco S R L filed Critical Inalco S R L
Priority to IT102017000085508A priority Critical patent/IT201700085508A1/it
Priority to PT187557228T priority patent/PT3658524T/pt
Priority to ES18755722T priority patent/ES2901132T3/es
Priority to PCT/EP2018/070275 priority patent/WO2019020738A1/en
Priority to JP2020503952A priority patent/JP7196153B2/ja
Priority to CA3071053A priority patent/CA3071053A1/en
Priority to RU2020108066A priority patent/RU2796921C2/ru
Priority to MX2020000955A priority patent/MX2020000955A/es
Priority to PL18755722T priority patent/PL3658524T3/pl
Priority to AU2018308925A priority patent/AU2018308925B2/en
Priority to UAA202000718A priority patent/UA126811C2/uk
Priority to CN201880050039.0A priority patent/CN110997607B/zh
Priority to MA049689A priority patent/MA49689A/fr
Priority to US16/634,311 priority patent/US11505518B2/en
Priority to BR112020001704-3A priority patent/BR112020001704A2/pt
Priority to EP18755722.8A priority patent/EP3658524B1/en
Publication of IT201700085508A1 publication Critical patent/IT201700085508A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/004—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by obtaining phenols from plant material or from animal material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/02—Solvent extraction of solids
    • B01D11/0288—Applications, solvents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0492—Applications, solvents used
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0004—Crystallisation cooling by heat exchange
    • B01D9/0013—Crystallisation cooling by heat exchange by indirect heat exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/004—Fractional crystallisation; Fractionating or rectifying columns
    • B01D9/0045—Washing of crystals, e.g. in wash columns
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/50—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions decreasing the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/68—Purification; separation; Use of additives, e.g. for stabilisation
    • C07C37/70—Purification; separation; Use of additives, e.g. for stabilisation by physical treatment
    • C07C37/84—Purification; separation; Use of additives, e.g. for stabilisation by physical treatment by crystallisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Botany (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT102017000085508A 2017-07-26 2017-07-26 Metodo per la produzione di cannabinoidi da varietà di canapa industriale IT201700085508A1 (it)

Priority Applications (16)

Application Number Priority Date Filing Date Title
IT102017000085508A IT201700085508A1 (it) 2017-07-26 2017-07-26 Metodo per la produzione di cannabinoidi da varietà di canapa industriale
PT187557228T PT3658524T (pt) 2017-07-26 2018-07-26 Método para a produção de canabinóides a partir de tipos de cânhamo industrial
ES18755722T ES2901132T3 (es) 2017-07-26 2018-07-26 Método para la producción de cannabinoides a partir de tipos de cáñamo industrial
PCT/EP2018/070275 WO2019020738A1 (en) 2017-07-26 2018-07-26 PROCESS FOR PRODUCING CANNABINOIDS FROM TYPES OF INDUSTRIAL HEMP
JP2020503952A JP7196153B2 (ja) 2017-07-26 2018-07-26 工業用大麻のタイプからのカンナビノイドの製造方法
CA3071053A CA3071053A1 (en) 2017-07-26 2018-07-26 Method for the production of cannabinoids from types of industrial hemp
RU2020108066A RU2796921C2 (ru) 2017-07-26 2018-07-26 Способ получения каннабиноидов из сортов технической конопли
MX2020000955A MX2020000955A (es) 2017-07-26 2018-07-26 Método para la producción de cannabinoides a partir de tipos de cáñamo industrial.
PL18755722T PL3658524T3 (pl) 2017-07-26 2018-07-26 Sposób wytwarzania kannabinoidów z przemysłowych typów konopi
AU2018308925A AU2018308925B2 (en) 2017-07-26 2018-07-26 Method for the production of cannabinoids from types of industrial hemp
UAA202000718A UA126811C2 (uk) 2017-07-26 2018-07-26 Спосіб одержання канабіноїдів з коноплі деяких промислових сортів
CN201880050039.0A CN110997607B (zh) 2017-07-26 2018-07-26 用于从工业大麻类生产大麻素的方法
MA049689A MA49689A (fr) 2017-07-26 2018-07-26 Procédé de production de cannabinoïdes à partir de types de chanvre industriel
US16/634,311 US11505518B2 (en) 2017-07-26 2018-07-26 Method for the production of cannabinoids from types of industrial hemp
BR112020001704-3A BR112020001704A2 (pt) 2017-07-26 2018-07-26 método para a produção de cannabinoides a partir de tipos de cânhamo industrial
EP18755722.8A EP3658524B1 (en) 2017-07-26 2018-07-26 Method for the production of cannabinoids from types of industrial hemp

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102017000085508A IT201700085508A1 (it) 2017-07-26 2017-07-26 Metodo per la produzione di cannabinoidi da varietà di canapa industriale

Publications (1)

Publication Number Publication Date
IT201700085508A1 true IT201700085508A1 (it) 2019-01-26

Family

ID=60451089

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102017000085508A IT201700085508A1 (it) 2017-07-26 2017-07-26 Metodo per la produzione di cannabinoidi da varietà di canapa industriale

Country Status (15)

Country Link
US (1) US11505518B2 (it)
EP (1) EP3658524B1 (it)
JP (1) JP7196153B2 (it)
CN (1) CN110997607B (it)
AU (1) AU2018308925B2 (it)
BR (1) BR112020001704A2 (it)
CA (1) CA3071053A1 (it)
ES (1) ES2901132T3 (it)
IT (1) IT201700085508A1 (it)
MA (1) MA49689A (it)
MX (1) MX2020000955A (it)
PL (1) PL3658524T3 (it)
PT (1) PT3658524T (it)
UA (1) UA126811C2 (it)
WO (1) WO2019020738A1 (it)

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GB2530001B (en) 2014-06-17 2019-01-16 Gw Pharma Ltd Use of cannabidiol in the reduction of convulsive seizure frequency in treatment-resistant epilepsy
GB2531281A (en) 2014-10-14 2016-04-20 Gw Pharma Ltd Use of cannabidiol in the treatment of intractable epilepsy
US10239808B1 (en) 2016-12-07 2019-03-26 Canopy Holdings, LLC Cannabis extracts
WO2019152736A1 (en) 2018-01-31 2019-08-08 Canopy Holdings, LLC Hemp powder
US10843102B2 (en) * 2018-06-29 2020-11-24 Senti Solutions Inc. Resinous compound crystallization using non-polar solvent sequence
CA3073093A1 (en) 2018-08-03 2020-02-06 Biomass Oil Separation Solutions, Llc Processes and apparatus for extraction of substances and enriched extracts from plant material
US11040932B2 (en) 2018-10-10 2021-06-22 Treehouse Biotech, Inc. Synthesis of cannabigerol
CA3130256A1 (en) * 2019-02-15 2020-08-20 Ebers Tech Inc. L-pipecolic acid cocrystal of cannabidiol
CN111848364B (zh) * 2019-04-30 2021-04-02 云南汉盟制药有限公司 从大麻中提取大麻二酚的方法
WO2021012044A1 (en) 2019-07-22 2021-01-28 Canopy Growth Corporation Continuous crystallization of cannabinoids in a stirred-tank reactor
US10799546B1 (en) 2019-07-26 2020-10-13 Biomass Oil Separation Solutions, Llc Modular, integrated process and apparatus for extracting, refining and remediating active substances from plant material
WO2021034718A1 (en) * 2019-08-22 2021-02-25 Medpharm Iowa Llc Water-based extraction and purification processes for cannabinoid acids
US10858303B1 (en) * 2019-10-30 2020-12-08 Heinkel Filtering Systems, Inc. Cannabidiol isolate production systems and methods
US10751640B1 (en) * 2019-10-30 2020-08-25 Heinkel Filtering Systems, Inc. Cannabidiol isolate production systems and methods
WO2021113083A1 (en) 2019-12-06 2021-06-10 JLABS Beauty LLC Topical compositions containing rose oil and cannabidiol and methods of making and using the same
US11291699B1 (en) 2019-12-13 2022-04-05 Delmarva Hemp, LLC Method for solvent-free extraction and concentration of full spectrum of cannabinoids in a carrier oil
US11351476B2 (en) * 2020-01-07 2022-06-07 Agrify Corporation Method for chemical separation of cannabinoids
GB202002754D0 (en) 2020-02-27 2020-04-15 Gw Res Ltd Methods of treating tuberous sclerosis complex with cannabidiol and everolimus
US11813549B1 (en) 2020-03-04 2023-11-14 Eco-Logic Environmental Engineering Inc. Devices and methods for essential oils, terpenes, flavonoids, and hydrosols extraction
EP4153306A1 (en) 2020-05-22 2023-03-29 Ilera Derm LLC Compositions for treating acne and dermatological conditions
US20210370198A1 (en) * 2020-05-29 2021-12-02 Chemtor, Lp Purification and extraction of cannabinoids
CN111792981B (zh) * 2020-06-24 2023-05-02 深圳市云麻生物科技有限公司 一种大麻二酚的提纯方法
CA3189932A1 (en) * 2020-09-02 2022-03-10 Purcann Pharma Inc. Method for producing a purified cannabinoid extract, and a purified cannabinoid extract obtained therefrom
GB202013765D0 (en) * 2020-09-02 2020-10-14 Gw Res Ltd Method of preparing cannabinoids
CN112057894A (zh) * 2020-09-08 2020-12-11 云南工麻生物科技有限公司 一种提取大麻二酚的方法
WO2022140197A1 (en) * 2020-12-23 2022-06-30 M-For, LLC Extraction and purification of cannabinoids
PE20231737A1 (es) * 2021-03-23 2023-10-31 Pobeltsch Gle Ad Metodos y sistemas para el extraccion de cannabinoides
WO2023209046A1 (en) 2022-04-27 2023-11-02 GW Research Limited Treatment of spasticity and pain in renally-impaired patients
EP4374864A1 (en) * 2022-11-23 2024-05-29 Bioactive Botanicals Swiss AG Method for preparing thc-reduced cannabis plant extract
KR102585373B1 (ko) 2023-04-03 2023-10-06 한국콜마주식회사 헴프로부터 칸나비디올을 정제하는 방법 및 이에 의해 정제되는 칸나비디올
KR102641482B1 (ko) * 2023-05-18 2024-02-28 재단법인춘천바이오산업진흥원 고순도의 칸나비디올 정제 및 결정 제조방법

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060167283A1 (en) * 2002-09-23 2006-07-27 Ian Flockhart Method of preparing cannabidiol from plant material
US20150038567A1 (en) * 2011-09-29 2015-02-05 The Health Concept Gmbh Cannabinoid Carboxylic Acids, Salts of Cannabinoid Carboxylic Acids, and the Production and Uses of Same
US20150203434A1 (en) * 2002-09-23 2015-07-23 Gw Pharma Limited Methods of preparing cannabinoids from plant material
US20160214920A1 (en) * 2015-01-22 2016-07-28 Phytoplant Research S.L. Methods of Purifying Cannabinoids, Compositions and Kits Thereof
WO2016187679A1 (en) * 2015-05-22 2016-12-01 "Pobelch - Gle" Ood Method for preparation of a cannabinoid extract from hemp
US20170022132A1 (en) * 2014-07-02 2017-01-26 Cv Sciences, Inc. Novel process for generating hemp oil with a high cannabidiol (cbd) content

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AU2003205844B2 (en) * 2002-02-01 2006-10-12 Resolution Chemicals Limited Production of Delta 9 tetrahydrocannabinol
EP3274321B8 (en) 2015-03-23 2019-10-23 Echo Pharmaceuticals B.V. Cannabidiol isolate from industrial-hemp and use thereof in pharmaceutical and/or cosmetic preparations
CN106278828A (zh) * 2016-08-16 2017-01-04 云南汉素生物科技有限公司 一种从工业大麻花叶中提取大麻二酚的方法
US10189762B1 (en) * 2017-07-07 2019-01-29 Orochem Technologies, Inc. Process for purification and separation of cannabinoids, from dried hemp and cannabis leaves

Patent Citations (6)

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Publication number Priority date Publication date Assignee Title
US20060167283A1 (en) * 2002-09-23 2006-07-27 Ian Flockhart Method of preparing cannabidiol from plant material
US20150203434A1 (en) * 2002-09-23 2015-07-23 Gw Pharma Limited Methods of preparing cannabinoids from plant material
US20150038567A1 (en) * 2011-09-29 2015-02-05 The Health Concept Gmbh Cannabinoid Carboxylic Acids, Salts of Cannabinoid Carboxylic Acids, and the Production and Uses of Same
US20170022132A1 (en) * 2014-07-02 2017-01-26 Cv Sciences, Inc. Novel process for generating hemp oil with a high cannabidiol (cbd) content
US20160214920A1 (en) * 2015-01-22 2016-07-28 Phytoplant Research S.L. Methods of Purifying Cannabinoids, Compositions and Kits Thereof
WO2016187679A1 (en) * 2015-05-22 2016-12-01 "Pobelch - Gle" Ood Method for preparation of a cannabinoid extract from hemp

Also Published As

Publication number Publication date
CN110997607A (zh) 2020-04-10
AU2018308925B2 (en) 2022-02-17
PT3658524T (pt) 2021-12-03
ES2901132T3 (es) 2022-03-21
RU2020108066A (ru) 2021-08-26
UA126811C2 (uk) 2023-02-08
EP3658524B1 (en) 2021-09-08
CN110997607B (zh) 2023-05-09
MA49689A (fr) 2020-06-03
US20200181050A1 (en) 2020-06-11
RU2020108066A3 (it) 2021-10-22
JP2020528066A (ja) 2020-09-17
AU2018308925A1 (en) 2020-03-12
BR112020001704A2 (pt) 2020-07-21
WO2019020738A1 (en) 2019-01-31
PL3658524T3 (pl) 2022-05-02
MX2020000955A (es) 2020-07-22
CA3071053A1 (en) 2019-01-31
EP3658524A1 (en) 2020-06-03
JP7196153B2 (ja) 2022-12-26
US11505518B2 (en) 2022-11-22

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