ZA200001851B - Stable crystalline salts of 5-methyltetrahydrofolic acid. - Google Patents

Stable crystalline salts of 5-methyltetrahydrofolic acid.

Info

Publication number
ZA200001851B
ZA200001851B ZA200001851A ZA200001851A ZA200001851B ZA 200001851 B ZA200001851 B ZA 200001851B ZA 200001851 A ZA200001851 A ZA 200001851A ZA 200001851 A ZA200001851 A ZA 200001851A ZA 200001851 B ZA200001851 B ZA 200001851B
Authority
ZA
South Africa
Prior art keywords
crystalline salts
stable crystalline
methyltetrahydrofolic acid
methyl
tetrahydrofolic acid
Prior art date
Application number
ZA200001851A
Other languages
English (en)
Inventor
Hans Rudolf Mueller
Rudolf Moser
Thomas Egger
Original Assignee
Eprova Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4193016&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200001851(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eprova Ag filed Critical Eprova Ag
Publication of ZA200001851B publication Critical patent/ZA200001851B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • C07D475/02Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Neurosurgery (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200001851A 1999-04-15 2000-04-12 Stable crystalline salts of 5-methyltetrahydrofolic acid. ZA200001851B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH00695/99A CH693905A5 (de) 1999-04-15 1999-04-15 Stabile kristalline Salze von 5-Methyltetrahydrofolsäure.

Publications (1)

Publication Number Publication Date
ZA200001851B true ZA200001851B (en) 2000-12-06

Family

ID=4193016

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200001851A ZA200001851B (en) 1999-04-15 2000-04-12 Stable crystalline salts of 5-methyltetrahydrofolic acid.

Country Status (19)

Country Link
US (1) US6441168B1 (hu)
EP (5) EP2192120B1 (hu)
JP (4) JP5202774B2 (hu)
KR (2) KR100774012B1 (hu)
CN (1) CN1154648C (hu)
AT (2) ATE451372T1 (hu)
AU (1) AU782641B2 (hu)
CA (1) CA2305926C (hu)
CH (1) CH693905A5 (hu)
CY (2) CY1109874T1 (hu)
DE (2) DE50015815D1 (hu)
DK (4) DK1044975T3 (hu)
ES (3) ES2374371T3 (hu)
HU (1) HU229423B1 (hu)
NO (1) NO325495B1 (hu)
PT (4) PT1044975E (hu)
RU (1) RU2265605C2 (hu)
TW (1) TWI285205B (hu)
ZA (1) ZA200001851B (hu)

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CH693905A5 (de) * 1999-04-15 2004-04-15 Eprova Ag Stabile kristalline Salze von 5-Methyltetrahydrofolsäure.
US20020094970A1 (en) * 2000-12-14 2002-07-18 Ronenn Roubenoff Compositions and methods for treating an arthritic condition
DK1708690T3 (en) 2003-11-17 2016-11-07 Biomarin Pharm Inc TREATMENT OF PHENYLKETONURI WITH BH4
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AU2005313940A1 (en) * 2004-12-08 2006-06-15 Biomarin Pharmaceutical Inc. Methods and compositions for the treatment of pulmonary hypertension of the newborn
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US8617597B2 (en) * 2006-07-06 2013-12-31 Bayer Intellectual Property Gmbh Pharmaceutical composition containing a tetrahydrofolic acid
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EP2027855A1 (de) 2007-08-24 2009-02-25 Bayer Schering Pharma AG Verwendung von Gestagenen in Kombination mit (6S)5-Methyltetrahydrofolat zur Therapie der Endometriose mit gleichzeitiger Verminderung von Therapie-Nebenwirkungen sowie der Verminderung des Risikos angeborener Fehlbildungen bei Eintritt einer Gravidität
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WO2013163917A1 (zh) * 2012-04-13 2013-11-07 连云港金康和信药业有限公司 化合物jk12a及其制备
CN103450202B (zh) * 2012-06-04 2015-07-01 南京莱因医药科技有限公司 L-5-甲基四氢叶酸与有机碱加成盐的方法
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Also Published As

Publication number Publication date
JP2013047280A (ja) 2013-03-07
PT2194057E (pt) 2012-01-16
CY1109874T1 (el) 2014-09-10
DE50016064D1 (de) 2011-03-03
JP5675760B2 (ja) 2015-02-25
EP2192120B1 (de) 2011-10-26
DK2189459T3 (da) 2011-04-18
ES2336190T3 (es) 2010-04-09
DK1044975T3 (da) 2010-03-22
NO20001886L (no) 2000-10-16
KR20070062964A (ko) 2007-06-18
TWI285205B (en) 2007-08-11
HUP0001560A3 (en) 2003-04-28
JP5675759B2 (ja) 2015-02-25
HU229423B1 (en) 2013-12-30
AU782641B2 (en) 2005-08-18
JP2013047278A (ja) 2013-03-07
DK2194057T3 (da) 2012-01-16
KR100874368B1 (ko) 2008-12-16
KR100774012B1 (ko) 2007-11-08
JP2013047279A (ja) 2013-03-07
NO20001886D0 (no) 2000-04-12
EP1044975B1 (de) 2009-12-09
CA2305926A1 (en) 2000-10-15
EP2194057A1 (de) 2010-06-09
EP2192120A1 (de) 2010-06-02
HU0001560D0 (en) 2000-06-28
NO325495B1 (no) 2008-05-19
JP5675758B2 (ja) 2015-02-25
DK2192120T3 (da) 2012-01-16
HUP0001560A2 (hu) 2001-04-28
AU2768900A (en) 2000-10-19
PT1044975E (pt) 2010-03-09
EP1695975A1 (de) 2006-08-30
CH693905A5 (de) 2004-04-15
DE50015815D1 (de) 2010-01-21
CA2305926C (en) 2008-10-07
KR20010014732A (ko) 2001-02-26
CY1111313T1 (el) 2015-08-05
ATE451372T1 (de) 2009-12-15
JP2000327680A (ja) 2000-11-28
ES2374369T3 (es) 2012-02-16
CN1277197A (zh) 2000-12-20
EP2189459B1 (de) 2011-01-19
US6441168B1 (en) 2002-08-27
EP2189459A1 (de) 2010-05-26
ES2374371T3 (es) 2012-02-16
PT2192120E (pt) 2012-01-16
JP5202774B2 (ja) 2013-06-05
CN1154648C (zh) 2004-06-23
PT2189459E (pt) 2011-04-14
EP1044975A1 (de) 2000-10-18
ATE496052T1 (de) 2011-02-15
EP2194057B1 (de) 2011-10-26
RU2265605C2 (ru) 2005-12-10

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