UY32836A - Partículas estabilizadas que comprenden 5-metil-(6s)-tetrahidrofolato - Google Patents
Partículas estabilizadas que comprenden 5-metil-(6s)-tetrahidrofolatoInfo
- Publication number
- UY32836A UY32836A UY0001032836A UY32836A UY32836A UY 32836 A UY32836 A UY 32836A UY 0001032836 A UY0001032836 A UY 0001032836A UY 32836 A UY32836 A UY 32836A UY 32836 A UY32836 A UY 32836A
- Authority
- UY
- Uruguay
- Prior art keywords
- methyl
- tetrahydropholate
- stabilized particles
- particles
- earth metal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7007—Drug-containing films, membranes or sheets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
Abstract
Pequeñas partículas estabilizadas que comprenden una forma cristalina de una sal 5-metil-(6S)-tetrahidrofolato de metal alcalino térreo y por lo menos un agente protector. Dichas partículas confieren estabilidad a la sal 5-metil-(6S)-tetrahidrofolato de metal alcalino térreo, y se incorporan convenientemente a formas de dosificación unitaria, como por ejemplo a láminas .
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09167733 | 2009-08-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
UY32836A true UY32836A (es) | 2011-03-31 |
Family
ID=43037665
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY0001032836A UY32836A (es) | 2009-08-12 | 2010-08-09 | Partículas estabilizadas que comprenden 5-metil-(6s)-tetrahidrofolato |
Country Status (9)
Country | Link |
---|---|
US (1) | US20120263762A1 (es) |
EP (1) | EP2464331A1 (es) |
JP (1) | JP2013501753A (es) |
CN (1) | CN102612358A (es) |
AR (1) | AR077843A1 (es) |
CA (1) | CA2769803A1 (es) |
TW (1) | TW201110969A (es) |
UY (1) | UY32836A (es) |
WO (1) | WO2011018482A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2878600B1 (en) | 2013-12-02 | 2018-06-27 | Cerbios-Pharma S.A. | Stable complexes of an alkaline earth metal salt of N5-methyl-tetrahydrofolic acid and a polyol |
WO2016034145A1 (zh) | 2014-09-04 | 2016-03-10 | 连云港金康和信药业有限公司 | (6s)-5-甲基四氢叶酸或其盐组合物及其制备和应用 |
CN108186586B (zh) * | 2018-03-01 | 2020-12-29 | 常州市第四制药厂有限公司 | 一种烯丙雌醇片剂及其制备方法 |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56140915A (en) * | 1980-04-07 | 1981-11-04 | Yamanouchi Pharmaceut Co Ltd | Pharmaceutical preparation for solid drug |
DE3347125A1 (de) | 1983-12-22 | 1985-07-11 | Schering AG, 1000 Berlin und 4709 Bergkamen | Mehrstufenkombinationspraeparat und seine verwendung zur oralen kontrazeption |
US4800087A (en) | 1986-11-24 | 1989-01-24 | Mehta Atul M | Taste-masked pharmaceutical compositions |
DE4426709A1 (de) | 1994-07-20 | 1996-01-25 | Schering Ag | Steroidale Sexualhormone enthaltende feste Arzneiformen |
CH693255A5 (de) | 1997-06-13 | 2003-05-15 | Eprova Ag | Verwendung von Tetrahydrofolaten in der natürlichenstereoisomeren Form zur Herstellung einer pharmazeutischenZubereitung geeignet zur Beeinflussung des Homocystein-Spiegels. |
CN1240387C (zh) | 1998-04-17 | 2006-02-08 | 奥索一麦克尼尔药品公司 | 含有叶酸的药用组合物及其用途和给药系统 |
EP1133282A4 (en) | 1998-11-25 | 2006-03-29 | Cima Labs Inc | TASTE-MAKING DELIVERY SYSTEM WITH FAST RELEASE |
US6552024B1 (en) | 1999-01-21 | 2003-04-22 | Lavipharm Laboratories Inc. | Compositions and methods for mucosal delivery |
CH693905A5 (de) | 1999-04-15 | 2004-04-15 | Eprova Ag | Stabile kristalline Salze von 5-Methyltetrahydrofolsäure. |
DE122009000006I2 (de) | 1999-08-31 | 2012-03-22 | Bayer Schering Pharma | Pharmazeutische kombination von ethinylestradiol und drospirenone als empfangnisverhutendes mittel. |
DE60113809T2 (de) | 2000-01-18 | 2006-06-22 | Schering Ag | Pharmazeutische kombination aus mikronisiertem drospirenon und einen estrogen für die hormonersatztherapie |
EP1216713A1 (en) | 2000-12-20 | 2002-06-26 | Schering Aktiengesellschaft | Compositions of estrogen-cyclodextrin complexes |
EP1216712A1 (en) | 2000-12-20 | 2002-06-26 | Schering Aktiengesellschaft | Cyclodextrin-drospirenone inclusion complexes |
CA2419089A1 (en) | 2001-07-27 | 2003-03-05 | Tatsuki Shinoda | Composition comprises sustained-release fine particles for quick-disintegrating tablets in the buccal cavity and manufacturing method thereof |
ATE536868T1 (de) | 2001-10-12 | 2011-12-15 | Monosolrx Llc | Einheitliche filme als schnell auflösende verabreichungsformen enthaltend geschmacksmaskiereden stoff |
US20060057207A1 (en) * | 2001-11-30 | 2006-03-16 | Pfizer Inc | Fast-disintegrating dosage forms of 5,8,14-triazatetracyclo[10.3.1.02,11.04,9]-hexadeca-2(11),3,5,7,9-pentaene |
AU2002343249B2 (en) | 2002-02-21 | 2009-02-05 | Bayer Schering Pharma Aktiengesellschaft | Pharmaceutical compositions comprising one or more steroids one or more tetrahydrofolate components and vitamin B12 |
US8153161B2 (en) | 2003-12-09 | 2012-04-10 | Dainippon Sumitomo Pharma Co., Ltd. | Medicament-containing particle and a solid preparation containing the particle |
US9050249B2 (en) | 2004-04-30 | 2015-06-09 | Astellas Pharma Inc. | Oral pharmaceutical compositions in timed-release particle form and fast-disintegrating tablets containing this composition |
US20060105038A1 (en) | 2004-11-12 | 2006-05-18 | Eurand Pharmaceuticals Limited | Taste-masked pharmaceutical compositions prepared by coacervation |
DE102005062270A1 (de) | 2005-12-24 | 2007-06-28 | Bayer Technology Services Gmbh | Geschmacksmaskierung von Pulvern |
WO2007074472A2 (en) | 2005-12-27 | 2007-07-05 | Jubilant Organosys Limited | Mouth dissolving pharmaceutical composition and process for preparing the same using a high amount of silicon dioxide |
DE102006003512A1 (de) | 2006-01-24 | 2007-08-02 | Bayer Schering Pharma Ag | Plättchenförmige Arzneimittel zur transbukkalen Applikation von Arzneistoffen |
US8986735B2 (en) | 2006-03-16 | 2015-03-24 | Novartis Ag | Solid dosage form containing a taste masked active agent |
US20070292508A1 (en) * | 2006-06-05 | 2007-12-20 | Balchem Corporation | Orally disintegrating dosage forms |
CN101489563A (zh) * | 2006-07-06 | 2009-07-22 | 拜耳先灵医药股份有限公司 | 用于避孕和预防先天性畸形风险的药物制剂 |
NZ575900A (en) | 2006-10-02 | 2012-04-27 | Labtec Gmbh | Non-mucoadhesive film dosage forms |
-
2010
- 2010-08-09 UY UY0001032836A patent/UY32836A/es not_active Application Discontinuation
- 2010-08-11 TW TW099126805A patent/TW201110969A/zh unknown
- 2010-08-11 JP JP2012524231A patent/JP2013501753A/ja active Pending
- 2010-08-11 CA CA2769803A patent/CA2769803A1/en not_active Abandoned
- 2010-08-11 CN CN2010800392309A patent/CN102612358A/zh active Pending
- 2010-08-11 AR ARP100102934A patent/AR077843A1/es unknown
- 2010-08-11 EP EP10742494A patent/EP2464331A1/en not_active Withdrawn
- 2010-08-11 WO PCT/EP2010/061703 patent/WO2011018482A1/en active Application Filing
- 2010-08-11 US US13/390,315 patent/US20120263762A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AR077843A1 (es) | 2011-09-28 |
CN102612358A (zh) | 2012-07-25 |
US20120263762A1 (en) | 2012-10-18 |
JP2013501753A (ja) | 2013-01-17 |
WO2011018482A1 (en) | 2011-02-17 |
EP2464331A1 (en) | 2012-06-20 |
CA2769803A1 (en) | 2011-02-17 |
TW201110969A (en) | 2011-04-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
109 | Application deemed to be withdrawn |
Effective date: 20181127 |