YU97583A - Process for obtaining new piperidine derivatives - Google Patents

Process for obtaining new piperidine derivatives

Info

Publication number
YU97583A
YU97583A YU00975/83A YU97583A YU97583A YU 97583 A YU97583 A YU 97583A YU 00975/83 A YU00975/83 A YU 00975/83A YU 97583 A YU97583 A YU 97583A YU 97583 A YU97583 A YU 97583A
Authority
YU
Yugoslavia
Prior art keywords
piperidine derivatives
obtaining new
new piperidine
obtaining
derivatives
Prior art date
Application number
YU00975/83A
Other languages
English (en)
Inventor
J L Archibald
T J Ward
Original Assignee
Wyeth John & Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd
Publication of YU97583A publication Critical patent/YU97583A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
YU00975/83A 1980-03-01 1983-05-04 Process for obtaining new piperidine derivatives YU97583A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8007048 1980-03-01
GB8027435 1980-08-22

Publications (1)

Publication Number Publication Date
YU97583A true YU97583A (en) 1983-10-31

Family

ID=26274662

Family Applications (4)

Application Number Title Priority Date Filing Date
YU00473/81A YU47381A (en) 1980-03-01 1981-02-24 Process for obtaining new piperidine derivatives
YU00975/83A YU97583A (en) 1980-03-01 1983-05-04 Process for obtaining new piperidine derivatives
YU00974/83A YU97483A (en) 1980-03-01 1983-05-04 Process for obtaining new piperidine derivatives
YU00973/83A YU97383A (en) 1980-03-01 1983-05-04 Process for obtaining new piperidine derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
YU00473/81A YU47381A (en) 1980-03-01 1981-02-24 Process for obtaining new piperidine derivatives

Family Applications After (2)

Application Number Title Priority Date Filing Date
YU00974/83A YU97483A (en) 1980-03-01 1983-05-04 Process for obtaining new piperidine derivatives
YU00973/83A YU97383A (en) 1980-03-01 1983-05-04 Process for obtaining new piperidine derivatives

Country Status (20)

Country Link
US (2) US4426387A (xx)
EP (1) EP0035374B1 (xx)
KR (4) KR850000630B1 (xx)
AU (1) AU542950B2 (xx)
CA (1) CA1173037A (xx)
DE (1) DE3168564D1 (xx)
DK (1) DK164546C (xx)
EG (1) EG16004A (xx)
ES (4) ES499716A0 (xx)
FI (1) FI77231C (xx)
GR (1) GR73576B (xx)
HU (1) HU187768B (xx)
IE (1) IE52014B1 (xx)
IL (1) IL62200A (xx)
NO (1) NO156864C (xx)
NZ (1) NZ196324A (xx)
PH (1) PH17019A (xx)
PL (4) PL135545B1 (xx)
PT (1) PT72562B (xx)
YU (4) YU47381A (xx)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8528235D0 (en) * 1985-11-15 1985-12-18 Wyeth John & Brother Ltd Heterocyclic compounds
US4508722A (en) * 1981-05-18 1985-04-02 Eli Lilly And Company 1-Benzoyl-3-(arylpyridyl)urea compounds
DE3371511D1 (en) * 1982-04-07 1987-06-19 Ici Plc Quinoline derivatives
EP0093521B1 (en) * 1982-05-04 1988-08-24 Imperial Chemical Industries Plc Quinoline derivatives
FR2527205A1 (fr) * 1982-05-18 1983-11-25 Bouchara Emile Nouvelles phenyloxoalcoyl piperidines, leurs procedes d'obtention et les compositions pharmaceutiques en renfermant
ATE55378T1 (de) * 1983-09-19 1990-08-15 Bouchara Sa Substituierte, piperidinoguanidine, verfahren zu ihrer herstellung, und diese enthaltende pharmazeutische zusammensetzungen.
US4569933A (en) * 1984-04-13 1986-02-11 Cornu Pierre Jean Antihypertensive substituted derivatives of 2,5-diamino 1,4-diazole
GB8528234D0 (en) * 1985-11-15 1985-12-18 Wyeth John & Brother Ltd Heterocyclic compounds
US5312840A (en) * 1986-07-10 1994-05-17 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education Substituted guanidines having high binding to the sigma receptor and the use thereof
US5502255A (en) * 1986-07-10 1996-03-26 State Of Oregon Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Substituted guanidines having high binding to the sigma receptor and the use thereof
US4709094A (en) * 1986-07-10 1987-11-24 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Sigma brain receptor ligands and their use
EP0343307A1 (en) * 1988-05-26 1989-11-29 Fabrica Espanola De Productos Quimicos Y Farmaceuticos, S.A. 4-Piperidinealkanamine derivatives
GR1000662B (el) * 1988-07-01 1992-09-25 Janssen Pharmaceutica Nv Μεθοδος παρασκευης cis-ν-(3-μεθοξυ-4-πιπεριδινυλο)βενζαμιδιων.
US5262568A (en) * 1990-03-02 1993-11-16 State Of Oregon Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
CA2076664C (en) 1990-03-02 2004-01-13 Eckard Weber Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
FR2662162B1 (fr) * 1990-05-18 1995-01-20 Adir Nouveaux derives de l'amino piperidine, de l'amino pyrrolidine et de l'amino perhydroazepine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
JPH05508836A (ja) * 1990-05-25 1993-12-09 オレゴン州 シグマ受容体に対して高い結合性を有する置換グアニジンおよびその使用
US5741661A (en) * 1991-02-08 1998-04-21 Cambridge Neuroscience, Inc. Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers
US5847006A (en) * 1991-02-08 1998-12-08 Cambridge Neuroscience, Inc. Therapeutic guanidines
KR100246083B1 (ko) * 1991-02-08 2000-03-15 버틀러 그레고리 비. 신경전달물질의 방출조절물질인 치환 구아니딘류 및 그것의 유도체와 그들을 함유하는 약학 조성물
FR2690158B1 (fr) * 1992-04-17 1994-07-22 Sanofi Elf Nouveau derive arylpiperidinique, procede pour sa preparation et compositions pharmaceutiques le contenant.
ES2204920T3 (es) * 1993-05-27 2004-05-01 Cenes Limited Guanidinas substituidas terapeuticas.
US5739135A (en) * 1993-09-03 1998-04-14 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
JPH09505591A (ja) * 1993-11-23 1997-06-03 ケンブリッジ・ニューロサイエンス・インコーポレーテッド 治療用置換グアニジン類
KR100423272B1 (ko) 1994-02-03 2004-09-01 캠브리지 뉴로사이언스, 인코포레이티드 신경전달물질의방출을조절하는화합물,이의약학적으로허용가능한염및이를포함하는약학조성물
US7351743B1 (en) 1994-02-03 2008-04-01 Wyeth Therapeutic guanidines
US6143791A (en) * 1994-02-03 2000-11-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
US6787569B1 (en) 1994-02-03 2004-09-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
US6025355A (en) 1997-05-19 2000-02-15 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
US6242198B1 (en) 1996-07-25 2001-06-05 Cambridge Neuroscience, Inc. Methods of treatment of eye trauma and disorders
US6756389B2 (en) 1996-08-09 2004-06-29 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
DE19824470A1 (de) * 1998-05-30 1999-12-02 Boehringer Ingelheim Pharma Neue Neurokininantagonisten, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3072663A (en) * 1961-09-25 1963-01-08 Warner Lambert Pharmaceutical Polyalkyl substituted-4-guanidopiperidines
US3161637A (en) * 1961-10-10 1964-12-15 Res Lab Dr C Janssen N V 1-(gamma-aroyl-propyl)-4-(nu-arylcarbonyl amino) piperidines and related compounds
US3171838A (en) * 1961-10-10 1965-03-02 Res Lab Dr C Janssen N V Aroylalkyl and hydroxyaralkyl derivatives of 4-(n-arylalkanamido)-piperidines and related compounds
GB1411782A (en) * 1972-02-24 1975-10-29 Wyeth John & Brother Ltd Piperidine derivatives
GB1411783A (en) * 1972-02-24 1975-10-29 Wyeth John & Brother Ltd Piperidine derivatives
US3910930A (en) * 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
US4177279A (en) * 1973-10-10 1979-12-04 John Wyeth & Brother Ltd. 1-[(3-Indolyl)-alkyl]-piperidyl ureas and hypotensive compositions
GB1459506A (en) * 1974-02-18 1976-12-22 Wyeth John & Brother Ltd Piperidine derivatives
JPS5152176A (xx) 1974-10-12 1976-05-08 Yoshitomi Pharmaceutical
AU500990B2 (en) * 1975-07-25 1979-06-07 John Wyeth & Brother Limited Piperidine derivatives
JPS6039680B2 (ja) * 1975-12-22 1985-09-06 日本化薬株式会社 ３‐（メチルメルカプト）プロピルアミノブレオマイシンの製造法
JPS5285174A (en) * 1976-01-05 1977-07-15 Yoshitomi Pharmaceut Ind Ltd Novel urea or thiourea derivatives
GB1582239A (en) * 1976-12-11 1981-01-07 Wyeth John & Brother Ltd Piperidin-4-yl ureas and thioureas
GB1561023A (en) * 1977-04-22 1980-02-13 Beecham Group Ltd 2-methoxy - 5 - chloro aniline derivatives
IN148482B (xx) * 1977-06-03 1981-03-07 Pfizer
EP0000485A1 (de) * 1977-07-08 1979-02-07 Ciba-Geigy Ag Piperidino-propanole, ihre Herstellung und pharmazeutische Präparate die diese enthalten
US4281132A (en) * 1977-10-29 1981-07-28 John Wyeth & Brother Limited Piperidino ureas and thioureas
GB1586817A (en) * 1977-12-01 1981-03-25 Wyeth John & Brother Ltd Indole derivatives
US4169202A (en) * 1978-06-05 1979-09-25 American Home Products Corporation Process for preparing 4,5-dihydro-4-oxofuran-2-carboxylic acid derivatives
GB2034305B (en) * 1978-10-24 1982-12-22 Wyeth John & Brother Ltd Preparation of piperidine derivatives

Also Published As

Publication number Publication date
ES8203840A1 (es) 1982-05-01
EG16004A (en) 1986-12-30
IE52014B1 (en) 1987-05-27
US4426387A (en) 1984-01-17
PL229830A1 (xx) 1982-11-22
PL128409B1 (en) 1984-01-31
DK164546C (da) 1992-11-30
PL234317A1 (xx) 1982-08-16
YU97483A (en) 1983-10-31
NO156864B (no) 1987-08-31
PL135545B1 (en) 1985-11-30
ES8302657A1 (es) 1983-02-01
KR850001035B1 (ko) 1985-07-19
ES509164A0 (es) 1983-02-01
GR73576B (xx) 1984-03-20
US4563466A (en) 1986-01-07
NO156864C (no) 1987-12-09
KR850000630B1 (ko) 1985-05-06
IL62200A0 (en) 1981-03-31
PL234316A1 (en) 1983-11-07
EP0035374A2 (en) 1981-09-09
FI77231C (fi) 1989-02-10
AU542950B2 (en) 1985-03-28
FI77231B (fi) 1988-10-31
EP0035374A3 (en) 1981-11-11
IE810392L (en) 1981-09-01
DK87881A (da) 1981-09-02
AU6761481A (en) 1981-09-10
PH17019A (en) 1984-05-11
PL128510B1 (en) 1984-02-29
PL129174B1 (en) 1984-04-30
IL62200A (en) 1984-09-30
KR830005140A (ko) 1983-08-03
YU97383A (en) 1983-10-31
HU187768B (en) 1986-02-28
NZ196324A (en) 1983-09-02
ES499716A0 (es) 1982-05-01
PT72562B (en) 1982-06-20
KR850000631B1 (ko) 1985-05-06
PT72562A (en) 1981-03-01
ES509163A0 (es) 1983-02-01
ES8302656A1 (es) 1983-02-01
KR850002008A (ko) 1985-04-10
FI810587L (fi) 1981-09-02
NO810610L (no) 1981-09-02
PL234318A1 (xx) 1982-08-16
KR850002009A (ko) 1985-04-10
ES509165A0 (es) 1983-02-01
DK164546B (da) 1992-07-13
DE3168564D1 (en) 1985-03-14
KR850001063B1 (ko) 1985-07-25
EP0035374B1 (en) 1985-01-30
YU47381A (en) 1983-10-31
CA1173037A (en) 1984-08-21
KR850002007A (ko) 1985-05-06
ES8302658A1 (es) 1983-02-01

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