YU49108B - Ciklični peptidi i postupak za njihovo dobijanje - Google Patents

Ciklični peptidi i postupak za njihovo dobijanje

Info

Publication number
YU49108B
YU49108B YU18593A YU18593A YU49108B YU 49108 B YU49108 B YU 49108B YU 18593 A YU18593 A YU 18593A YU 18593 A YU18593 A YU 18593A YU 49108 B YU49108 B YU 49108B
Authority
YU
Yugoslavia
Prior art keywords
substituted
phenyl
formula
alkyl
group represented
Prior art date
Application number
YU18593A
Other languages
English (en)
Serbo-Croatian (sh)
Other versions
YU18593A (sh
Inventor
Joseph Frederick Burkhardt
Manuel Debono
Scott Jeffrey Nissen
Jr.Wilson William Turner
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of YU18593A publication Critical patent/YU18593A/sh
Publication of YU49108B publication Critical patent/YU49108B/sh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • C07K7/66Gramicidins S, C; Tyrocidins A, B, C; Related peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
YU18593A 1992-03-19 1993-03-18 Ciklični peptidi i postupak za njihovo dobijanje YU49108B (sh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85411792A 1992-03-19 1992-03-19
US99239092A 1992-12-16 1992-12-16

Publications (2)

Publication Number Publication Date
YU18593A YU18593A (sh) 1996-10-09
YU49108B true YU49108B (sh) 2004-03-12

Family

ID=27127211

Family Applications (1)

Application Number Title Priority Date Filing Date
YU18593A YU49108B (sh) 1992-03-19 1993-03-18 Ciklični peptidi i postupak za njihovo dobijanje

Country Status (25)

Country Link
EP (1) EP0561639B1 (online.php)
JP (3) JP3519754B2 (online.php)
KR (1) KR100256036B1 (online.php)
CN (1) CN1036715C (online.php)
AT (1) ATE217635T1 (online.php)
AU (2) AU3534193A (online.php)
BR (1) BR9301232A (online.php)
CA (1) CA2091663C (online.php)
CZ (1) CZ288974B6 (online.php)
DE (2) DE122008000006I2 (online.php)
DK (1) DK0561639T3 (online.php)
ES (1) ES2174843T3 (online.php)
FI (1) FI118768B (online.php)
HU (2) HU225783B1 (online.php)
IL (3) IL122315A (online.php)
LU (1) LU91406I2 (online.php)
MX (1) MX9301457A (online.php)
MY (1) MY136593A (online.php)
NL (1) NL300334I2 (online.php)
NO (1) NO930948L (online.php)
NZ (3) NZ512085A (online.php)
PT (1) PT561639E (online.php)
RU (1) RU2129562C1 (online.php)
TW (1) TW264477B (online.php)
YU (1) YU49108B (online.php)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5430018A (en) * 1991-10-17 1995-07-04 Merck & Co., Inc. Cyclohexapeptide with basic nitrogen containing alkylamide groups
US6743777B1 (en) 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
IL122315A (en) * 1992-03-19 2002-03-10 Lilly Co Eli Cyclic peptides and antifungal pharmaceutical compositions containing them
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
AU674233B2 (en) * 1993-05-04 1996-12-12 Merck & Co., Inc. Cyclohexapeptidyl aminoalkyl ethers
US5948753A (en) * 1993-05-04 1999-09-07 Merck & Co., Inc. Cyclohexapeptidyl propanolamine compounds
WO1995008341A1 (en) * 1993-09-22 1995-03-30 Merck & Co., Inc. Antifungal and anti-pneumocystis compounds, compositions containing such compounds, and methods of use
AU692308B2 (en) * 1994-09-16 1998-06-04 Merck Sharp & Dohme Corp. Aza cyclohexapeptide compounds
US5516757A (en) * 1994-09-16 1996-05-14 Merck & Co., Inc. Semi-synthetic lipopeptides, compositions containing said lipopeptides, and methods of use
US5514651A (en) * 1994-09-16 1996-05-07 Merck & Co., Inc. Aza cyclohexapeptide compounds
HU228151B1 (en) * 1994-10-07 2012-12-28 Astellas Pharma Inc Cyclic hexapeptides
US5516756A (en) * 1994-10-31 1996-05-14 Merck & Co., Inc. Aza cyclohexapeptide compounds
DE69615535T2 (de) * 1995-01-26 2002-05-02 Merck & Co., Inc. Neue fungizide cyclohexapeptide
US5646111A (en) * 1995-04-07 1997-07-08 Eli Lilly And Company Cyclic peptide antifungal Agents
US5652213A (en) * 1995-05-26 1997-07-29 Eli Lilly And Company Cyclic peptide antifungal agents
US5629290A (en) * 1995-05-26 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
US5786325A (en) * 1995-05-26 1998-07-28 Eli Lilly And Company Cyclic peptide antifungal agents and methods of making and using
US5618787A (en) * 1995-05-26 1997-04-08 Eli Lilly And Company Cyclic peptide antifungal agents
US5629289A (en) * 1995-07-25 1997-05-13 Eli Lilly And Company Cyclic peptide antifungal agents
US5693611A (en) * 1996-02-01 1997-12-02 Eli Lilly And Company Cyclic peptide antifungal agents
EP0881907A4 (en) * 1996-02-01 2000-05-10 Lilly Co Eli FUNGICIDES IN THE FORM OF CYCLIC PEPTIDES
JPH09227422A (ja) * 1996-02-12 1997-09-02 Rolic Ag シクロペンチル誘導体
US5696084A (en) * 1996-08-16 1997-12-09 Abbott Laboratories Amino-lipopetide antifungal agents
AUPO381496A0 (en) * 1996-11-25 1996-12-19 Fujisawa Pharmaceutical Co., Ltd. New compound
AU2003200556B2 (en) * 1997-12-10 2005-12-01 Novexel Echinocandin derivative and their preparation method
FR2784993B1 (fr) * 1998-10-26 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme fongicides
UA72200C2 (uk) * 1997-12-10 2005-02-15 Авентіс Фарма С.А. Похідні ехінокандину, спосіб їх одержання, їх застосування, проміжні сполуки та фармацевтична композиція
AUPP172898A0 (en) * 1998-02-09 1998-03-05 Fujisawa Pharmaceutical Co., Ltd. New compound
US6730776B1 (en) * 1998-03-16 2004-05-04 Fujisawa Pharmaceutical Co., Ltd. WF14573 or its salt, production thereof and use thereof
PT1107981E (pt) 1998-08-20 2005-05-31 Lilly Co Eli Sintese de analogos peptidicos ciclicos de anel modificado
ATE338059T1 (de) 1998-12-09 2006-09-15 Lilly Co Eli Reinigung von echinocandin cyclopeptiden
DE19907904A1 (de) 1999-02-24 2000-08-31 Clariant Gmbh Verfahren zur Herstellung von [1,1':4',1"]-Terphenylverbindungen
WO2000051567A1 (en) 1999-03-03 2000-09-08 Eli Lilly And Company Processes for making pharmaceutical oral ecb formulations and compositions
EP1157030B1 (en) 1999-03-03 2003-08-27 Eli Lilly And Company Echinocandin/carbohydrate complexes
DE60030415T2 (de) 1999-03-03 2007-08-30 Eli Lilly And Co., Indianapolis Bildung und anionenaustausch von inneren kristallinen ammoniumsalzen des echinocandins b
HK1040062A1 (zh) 1999-03-03 2002-05-24 Eli Lilly And Company 含有成胶束表面活性剂的棘白菌素药物配方
ES2248281T3 (es) * 2000-02-18 2006-03-16 Meiji Seika Kaisha, Ltd. Derivados de fenoxialquilamina utiles como agonistas del receptor opioide delta.
FR2833596B1 (fr) * 2001-12-14 2005-02-18 Aventis Pharma Sa Procede de preparation de derives d'echinocandine
US6991800B2 (en) 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
CN1812978A (zh) * 2003-04-30 2006-08-02 药物研发有限责任公司 作为蛋白酪氨酸磷酸酶-1b抑制剂的苯基取代羧酸
KR101551207B1 (ko) * 2008-09-04 2015-09-08 롬엔드하스전자재료코리아유한회사 신규한 유기 발광 화합물 및 이를 발광재료로서 채용하고 있는 유기 발광 소자
CN102464704B (zh) * 2010-11-05 2013-12-11 上海医药工业研究院 一种化合物及其制备方法和用途
KR102061486B1 (ko) * 2012-03-19 2020-01-03 시다라 세라퓨틱스, 인코포레이티드 에키노칸딘 계열의 화합물에 대한 투여 용법
ES2694561T3 (es) 2015-02-23 2018-12-21 Selectchemie Ag Composición de anidulafungina
JP6866583B2 (ja) * 2016-07-05 2021-04-28 Dic株式会社 液晶化合物
CN116903706B (zh) * 2023-06-13 2024-05-17 深圳市祥根生物有限公司 一种棘白菌素类药物及其制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE886575A (fr) * 1979-12-13 1981-06-10 Lilly Co Eli Derives de noyaux peptidiques cycliques, leur preparation et leur utilisation comme agents antifongiques
BE886576A (fr) * 1979-12-13 1981-06-10 Lilly Co Eli Derives de noyaux peptidiques cycliques, leur preparation et leur utilisation comme agents antifongiques
CA2037957A1 (en) * 1990-03-12 1991-09-13 Merck & Co., Inc. N-acylated cyclohexapeptide compounds
GB2241956A (en) * 1990-03-16 1991-09-18 Merck & Co Inc N-acylated cyclohexapeptide compounds
IL97347A0 (en) * 1990-03-19 1992-05-25 Merck & Co Inc Lipopeptide derivatives and antimicrobial compositions containing them
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
US5310726A (en) * 1990-03-19 1994-05-10 Merck & Co., Inc. Lipopeptide compounds
IL122315A (en) * 1992-03-19 2002-03-10 Lilly Co Eli Cyclic peptides and antifungal pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP0561639B1 (en) 2002-05-15
CA2091663A1 (en) 1993-09-20
NO930948D0 (no) 1993-03-16
JP2002226500A (ja) 2002-08-14
CZ41693A3 (en) 1994-07-13
MX9301457A (es) 1994-02-28
EP0561639A1 (en) 1993-09-22
HUT63637A (en) 1993-09-28
DE122008000006I2 (de) 2011-07-21
FI118768B (fi) 2008-03-14
ATE217635T1 (de) 2002-06-15
RU2129562C1 (ru) 1999-04-27
DE122008000006I1 (de) 2008-04-17
AU3534193A (en) 1993-09-23
IL122315A (en) 2002-03-10
MY136593A (en) 2008-10-31
IL122315A0 (en) 1998-04-05
HU225783B1 (en) 2007-09-28
PT561639E (pt) 2002-10-31
CZ288974B6 (cs) 2001-10-17
IL105048A (en) 2001-06-14
FI931202L (fi) 1993-09-20
DK0561639T3 (da) 2002-06-17
CN1080926A (zh) 1994-01-19
DE69331922T2 (de) 2002-08-29
JPH0656892A (ja) 1994-03-01
JP2004115540A (ja) 2004-04-15
HU211562A9 (en) 1995-12-28
BR9301232A (pt) 1993-09-21
JP3519754B2 (ja) 2004-04-19
CN1036715C (zh) 1997-12-17
NZ247149A (en) 1996-10-28
LU91406I2 (fr) 2008-03-10
AU6552996A (en) 1996-12-05
FI931202A0 (fi) 1993-03-18
KR930019694A (ko) 1993-10-18
NZ512085A (en) 2003-08-29
IL105048A0 (en) 1993-07-08
AU689391B2 (en) 1998-03-26
NO930948L (no) 1993-09-20
HU9300785D0 (en) 1993-06-28
ES2174843T3 (es) 2002-11-16
NL300334I1 (nl) 2008-03-03
JP3520071B2 (ja) 2004-04-19
KR100256036B1 (ko) 2000-05-01
NZ299314A (en) 2001-09-28
CA2091663C (en) 2007-10-30
TW264477B (online.php) 1995-12-01
YU18593A (sh) 1996-10-09
NL300334I2 (nl) 2008-05-01
DE69331922D1 (de) 2002-06-20

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