YU48645B - Kondenzovani diazepinoni i postupci za njihovo dobijanje - Google Patents
Kondenzovani diazepinoni i postupci za njihovo dobijanjeInfo
- Publication number
- YU48645B YU48645B YU32592A YU32592A YU48645B YU 48645 B YU48645 B YU 48645B YU 32592 A YU32592 A YU 32592A YU 32592 A YU32592 A YU 32592A YU 48645 B YU48645 B YU 48645B
- Authority
- YU
- Yugoslavia
- Prior art keywords
- group
- methods
- condensed diazepinones
- carbon atoms
- hydrogen atoms
- Prior art date
Links
- DHZYXWMZLAKTQV-UHFFFAOYSA-N diazepin-3-one Chemical class O=C1C=CC=CN=N1 DHZYXWMZLAKTQV-UHFFFAOYSA-N 0.000 title abstract 2
- -1 cyclopropyl- Chemical group 0.000 abstract 11
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000005073 adamantyl group Chemical group C12(CC3CC(CC(C1)C3)C2)* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Kondenzovani diazepinoni, opšte formule I u kojoj predstavljaju X, atom azota n, brojeve 3 i 4, R1, alkil grupu, sa pravim nizom, sa 1 do 4 atoma ugljenika, R2, razgranatu alkil grupu, 4 do 6 atoma ugljenika, ciklopropil-, ciklobutil-, ciklopentil-, cikloheksil-, cikloheptil-, metilciklopentil-, metilcikloheksil-, metilcikloheptil ili adamantil-grupu, R3 i R4, atome vodonika ili je jedan od tih ostataka metil-grupa ili atom halogena,i jedinjenja formule I, u kojoj X predstavlja =CH-grupu, n, broj 3, R1, etil-grupu, R2, 1,1-dimetilbutil-grupu, R3 i R4, predstavljaju atome vodonika,i njihove soli sa neorganskim ili organskim kiselinama. - Prijava sadrži još 1 nezavisan i 3 zavisnih zahteva.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SI9210325A SI9210325A (en) | 1991-04-12 | 1992-03-30 | Condensed diazepinones, process for their preparation and compositions containing them for the treatment of the central nervous system and to enhance cerebral perfusion |
| HRP-325/92A HRP940753A2 (en) | 1991-04-12 | 1994-10-25 | Condensed diazepinones, process for their preparation and compositions containing them for the treatment of the central nervous system and to enhance cerebral perfusion |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4112014A DE4112014A1 (de) | 1991-04-12 | 1991-04-12 | Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel zur behandlung von erkrankungen des zentralnervensystems und zur foerderung der cerebralen durchblutung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| YU32592A YU32592A (sh) | 1998-09-18 |
| YU48645B true YU48645B (sh) | 1999-06-15 |
Family
ID=6429483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU32592A YU48645B (sh) | 1991-04-12 | 1992-03-30 | Kondenzovani diazepinoni i postupci za njihovo dobijanje |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US5641772A (sh) |
| EP (1) | EP0508370B1 (sh) |
| JP (1) | JPH0597845A (sh) |
| KR (1) | KR100196969B1 (sh) |
| AT (1) | ATE140004T1 (sh) |
| AU (1) | AU653802B2 (sh) |
| CA (1) | CA2065800A1 (sh) |
| CZ (1) | CZ283399B6 (sh) |
| DE (2) | DE4112014A1 (sh) |
| DK (1) | DK0508370T3 (sh) |
| ES (1) | ES2090396T3 (sh) |
| FI (1) | FI97470C (sh) |
| GR (1) | GR3020860T3 (sh) |
| HR (1) | HRP940753A2 (sh) |
| HU (2) | HUT61301A (sh) |
| IE (1) | IE921147A1 (sh) |
| IL (1) | IL101560A (sh) |
| MX (1) | MX9201675A (sh) |
| NO (1) | NO180303C (sh) |
| NZ (1) | NZ242305A (sh) |
| PL (1) | PL169745B1 (sh) |
| RU (1) | RU2081870C1 (sh) |
| SG (1) | SG48793A1 (sh) |
| SI (1) | SI9210325A (sh) |
| SK (1) | SK279466B6 (sh) |
| TW (1) | TW205551B (sh) |
| YU (1) | YU48645B (sh) |
| ZA (1) | ZA922617B (sh) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4332168A1 (de) * | 1993-02-22 | 1995-03-23 | Thomae Gmbh Dr K | Cyclische Derivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| PT693070E (pt) * | 1993-04-05 | 2002-12-31 | Pharmaceutical Discovery Corp | Pirido(2,3-b)(1,4)benzodiazepinonas como ligando do receptor m2 para o tratamento de desordens neurologicas |
| WO1996013488A1 (fr) * | 1994-10-31 | 1996-05-09 | Yamanouchi Pharmaceutical Co., Ltd. | Nouveau derive de benzodiazepinone et composition medicinale constituee de celui-ci |
| US20070105835A1 (en) * | 2005-11-07 | 2007-05-10 | Kazantsev Aleksey G | Compositions and methods for modulating poly(ADP-ribose) polymerase activity |
| CA2691844A1 (en) * | 2007-07-02 | 2009-01-08 | Ac Immune S.A. | Therapeutic compound |
| KR102478480B1 (ko) | 2021-11-17 | 2022-12-19 | 주식회사 지농 | 통신 데이터 사용량을 최소화한 스마트팜 제어 및 동작확인 장치 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3409237A1 (de) * | 1984-03-14 | 1985-09-19 | Dr. Karl Thomae Gmbh, 7950 Biberach | Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3735895A1 (de) * | 1987-10-23 | 1989-05-03 | Thomae Gmbh Dr K | Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3919076A1 (de) * | 1989-06-10 | 1990-12-13 | Thomae Gmbh Dr K | Mittel zur behandlung von erkrankungen des zentralnervensystems und zur foerderung der cerebralen durchblutung |
-
1991
- 1991-04-12 DE DE4112014A patent/DE4112014A1/de not_active Withdrawn
-
1992
- 1992-03-30 YU YU32592A patent/YU48645B/sh unknown
- 1992-03-30 SI SI9210325A patent/SI9210325A/sl unknown
- 1992-04-07 DE DE59206679T patent/DE59206679D1/de not_active Expired - Fee Related
- 1992-04-07 SG SG1996001728A patent/SG48793A1/en unknown
- 1992-04-07 DK DK92105989.5T patent/DK0508370T3/da active
- 1992-04-07 EP EP92105989A patent/EP0508370B1/de not_active Expired - Lifetime
- 1992-04-07 ES ES92105989T patent/ES2090396T3/es not_active Expired - Lifetime
- 1992-04-07 AT AT92105989T patent/ATE140004T1/de not_active IP Right Cessation
- 1992-04-09 TW TW081102753A patent/TW205551B/zh active
- 1992-04-10 JP JP4089174A patent/JPH0597845A/ja active Pending
- 1992-04-10 IE IE114792A patent/IE921147A1/en not_active Application Discontinuation
- 1992-04-10 AU AU14814/92A patent/AU653802B2/en not_active Ceased
- 1992-04-10 CA CA002065800A patent/CA2065800A1/en not_active Abandoned
- 1992-04-10 IL IL10156092A patent/IL101560A/en not_active IP Right Cessation
- 1992-04-10 HU HU9201247A patent/HUT61301A/hu unknown
- 1992-04-10 MX MX9201675A patent/MX9201675A/es not_active IP Right Cessation
- 1992-04-10 FI FI921589A patent/FI97470C/fi active
- 1992-04-10 PL PL92294184A patent/PL169745B1/pl unknown
- 1992-04-10 RU SU925011249A patent/RU2081870C1/ru active
- 1992-04-10 NZ NZ242305A patent/NZ242305A/en unknown
- 1992-04-10 NO NO921447A patent/NO180303C/no unknown
- 1992-04-10 ZA ZA922617A patent/ZA922617B/xx unknown
- 1992-04-11 KR KR1019920006036A patent/KR100196969B1/ko not_active IP Right Cessation
- 1992-04-13 SK SK1111-92A patent/SK279466B6/sk unknown
- 1992-04-13 CZ CS921111A patent/CZ283399B6/cs not_active IP Right Cessation
-
1994
- 1994-10-25 HR HRP-325/92A patent/HRP940753A2/hr not_active Application Discontinuation
-
1995
- 1995-04-13 US US08/421,108 patent/US5641772A/en not_active Expired - Fee Related
- 1995-06-02 HU HU95P/P00158P patent/HU211156A9/hu unknown
-
1996
- 1996-08-22 GR GR960402217T patent/GR3020860T3/el unknown
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