YU47594B - KRISTALNA SO (4-DI-N-PROPIL)AMINO-6-AMINOKARBONIL-1,3,4,5-TETRAHIDROBENZ/cd/INDOLA I POSTUPAK ZA NJENO DOBIJANJE - Google Patents

KRISTALNA SO (4-DI-N-PROPIL)AMINO-6-AMINOKARBONIL-1,3,4,5-TETRAHIDROBENZ/cd/INDOLA I POSTUPAK ZA NJENO DOBIJANJE

Info

Publication number
YU47594B
YU47594B YU32791A YU32791A YU47594B YU 47594 B YU47594 B YU 47594B YU 32791 A YU32791 A YU 32791A YU 32791 A YU32791 A YU 32791A YU 47594 B YU47594 B YU 47594B
Authority
YU
Yugoslavia
Prior art keywords
indola
aminocarbonyl
propyl
amino
obtaining
Prior art date
Application number
YU32791A
Other languages
English (en)
Serbo-Croatian (sh)
Other versions
YU32791A (sh
Inventor
T.J. Kress
D.L. Varie
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of YU32791A publication Critical patent/YU32791A/sh
Publication of YU47594B publication Critical patent/YU47594B/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
YU32791A 1990-02-26 1991-02-25 KRISTALNA SO (4-DI-N-PROPIL)AMINO-6-AMINOKARBONIL-1,3,4,5-TETRAHIDROBENZ/cd/INDOLA I POSTUPAK ZA NJENO DOBIJANJE YU47594B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48518590A 1990-02-26 1990-02-26

Publications (2)

Publication Number Publication Date
YU32791A YU32791A (sh) 1994-01-20
YU47594B true YU47594B (sh) 1995-10-24

Family

ID=23927224

Family Applications (1)

Application Number Title Priority Date Filing Date
YU32791A YU47594B (sh) 1990-02-26 1991-02-25 KRISTALNA SO (4-DI-N-PROPIL)AMINO-6-AMINOKARBONIL-1,3,4,5-TETRAHIDROBENZ/cd/INDOLA I POSTUPAK ZA NJENO DOBIJANJE

Country Status (28)

Country Link
US (1) US5397799A (cg-RX-API-DMAC7.html)
EP (1) EP0444852B1 (cg-RX-API-DMAC7.html)
JP (1) JP3157007B2 (cg-RX-API-DMAC7.html)
KR (1) KR100208114B1 (cg-RX-API-DMAC7.html)
CN (1) CN1027503C (cg-RX-API-DMAC7.html)
AT (1) ATE126506T1 (cg-RX-API-DMAC7.html)
AU (1) AU629453B2 (cg-RX-API-DMAC7.html)
BR (1) BR9100767A (cg-RX-API-DMAC7.html)
CA (1) CA2037099C (cg-RX-API-DMAC7.html)
CY (1) CY1887A (cg-RX-API-DMAC7.html)
DE (1) DE69112099T2 (cg-RX-API-DMAC7.html)
DK (1) DK0444852T3 (cg-RX-API-DMAC7.html)
ES (1) ES2077796T3 (cg-RX-API-DMAC7.html)
FI (1) FI95464C (cg-RX-API-DMAC7.html)
GR (1) GR3017940T3 (cg-RX-API-DMAC7.html)
HK (1) HK175495A (cg-RX-API-DMAC7.html)
HU (1) HU217118B (cg-RX-API-DMAC7.html)
IE (1) IE67801B1 (cg-RX-API-DMAC7.html)
IL (1) IL97306A (cg-RX-API-DMAC7.html)
LV (1) LV10251B (cg-RX-API-DMAC7.html)
NO (1) NO174149C (cg-RX-API-DMAC7.html)
NZ (1) NZ237181A (cg-RX-API-DMAC7.html)
PT (1) PT96852B (cg-RX-API-DMAC7.html)
RU (2) RU2034837C1 (cg-RX-API-DMAC7.html)
SG (1) SG69975A1 (cg-RX-API-DMAC7.html)
TW (1) TW219933B (cg-RX-API-DMAC7.html)
YU (1) YU47594B (cg-RX-API-DMAC7.html)
ZA (1) ZA911258B (cg-RX-API-DMAC7.html)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL97308A (en) * 1990-02-26 1996-10-31 Lilly Co Eli 6-Substituted-hexahydrobenz (cd) indoles process for their preparation and pharmaceutical compositions containing them
US5302612A (en) * 1990-02-26 1994-04-12 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
IL97309A (en) * 1990-02-26 1996-11-14 Lilly Co Eli Intermediates for hexahydrobenz Úcd¾ indoles and process for the preparation of pure enantiomers thereof
US5364856A (en) * 1991-03-28 1994-11-15 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
US5643934A (en) * 1991-03-28 1997-07-01 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz [CD]indoles
TW248556B (cg-RX-API-DMAC7.html) * 1993-01-18 1995-06-01 Takeda Pharm Industry Co
UA53205C2 (en) * 2002-04-03 2006-06-15 Pharmatech Close Joint Stock C Antidepressant formulation and method for its manufacture
US7588924B2 (en) 2006-03-07 2009-09-15 Procter & Gamble Company Crystal of hypoxia inducible factor 1 alpha prolyl hydroxylase
AU2007265460B2 (en) 2006-06-26 2011-03-03 Akebia Therapeutics Inc. Prolyl hydroxylase inhibitors and methods of use
PH12012500788A1 (en) * 2009-11-06 2016-07-27 Aerpio Therapeutics Inc Compositions and methods for treating colitis
NO2686520T3 (cg-RX-API-DMAC7.html) 2011-06-06 2018-03-17
US8865748B2 (en) 2011-06-06 2014-10-21 Akebia Therapeutics Inc. Compounds and compositions for stabilizing hypoxia inducible factor-2 alpha as a method for treating cancer
MY204336A (en) 2013-06-13 2024-08-23 Akebia Therapeutics Inc Compositions and methods for treating anemia
CN114890943A (zh) 2013-11-15 2022-08-12 阿克比治疗有限公司 {[5-(3-氯苯基)-3-羟基吡啶-2-羰基]氨基}乙酸固体形式，组合物和用途
AU2016209126A1 (en) 2015-01-23 2017-08-10 Akebia Therapeutics, Inc. Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof
UA123308C2 (uk) 2015-04-01 2021-03-17 Екебіа Терапьютікс, Інк. Композиції і способи для лікування анемії
MX2020011845A (es) 2018-05-09 2021-01-15 Akebia Therapeutics Inc Proceso para preparar acido 2-[[5-(3-clorofenil)-3-hidroxipiridina -2-carbonil]amino]acetico.
US11524939B2 (en) 2019-11-13 2022-12-13 Akebia Therapeutics, Inc. Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110339A (en) * 1977-11-25 1978-08-29 Eli Lilly And Company 4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
US4576959A (en) * 1984-02-06 1986-03-18 Eli Lilly And Company 6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles
US4745126A (en) * 1987-03-12 1988-05-17 Eli Lilly And Company Method of treating anxiety with tetrahydrobenz[c,d]indole-6-carboxamides
DE3809155A1 (de) * 1988-03-18 1989-09-28 Bayer Ag 1,3,4,5-tetrahydrobenz-(c,d)-indole
US5204340A (en) * 1989-04-11 1993-04-20 Eli Lilly And Company Tetrahydrobenz(c,d)indole serotonin agonists
US5229409A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-tetrahydrobenz[cd]indoles

Also Published As

Publication number Publication date
GR3017940T3 (en) 1996-02-29
EP0444852A3 (en) 1992-02-19
CN1027503C (zh) 1995-01-25
LV10251A (lv) 1994-10-20
CA2037099A1 (en) 1991-08-27
ES2077796T3 (es) 1995-12-01
PT96852A (pt) 1991-10-31
IE910625A1 (en) 1991-08-28
RU2034837C1 (ru) 1995-05-10
YU32791A (sh) 1994-01-20
NO174149B (no) 1993-12-13
NO910735L (no) 1991-08-27
LV10251B (en) 1995-04-20
PT96852B (pt) 1998-07-31
CN1054589A (zh) 1991-09-18
ATE126506T1 (de) 1995-09-15
FI95464B (fi) 1995-10-31
AU7197191A (en) 1991-08-29
BR9100767A (pt) 1991-10-29
FI910895L (fi) 1991-08-27
IL97306A (en) 1996-10-16
DE69112099D1 (de) 1995-09-21
NO910735D0 (no) 1991-02-25
DK0444852T3 (da) 1995-12-11
FI95464C (fi) 1996-02-12
SG69975A1 (en) 2000-01-25
EP0444852B1 (en) 1995-08-16
HK175495A (en) 1995-11-24
US5397799A (en) 1995-03-14
IE67801B1 (en) 1996-05-01
NO174149C (no) 1994-03-23
JP3157007B2 (ja) 2001-04-16
HUT56542A (en) 1991-09-30
RU2083561C1 (ru) 1997-07-10
JPH04217662A (ja) 1992-08-07
KR910021375A (ko) 1991-12-20
NZ237181A (en) 1992-06-25
CY1887A (en) 1996-04-05
HU217118B (hu) 1999-11-29
TW219933B (cg-RX-API-DMAC7.html) 1994-02-01
FI910895A0 (fi) 1991-02-25
KR100208114B1 (ko) 1999-07-15
ZA911258B (en) 1992-10-28
EP0444852A2 (en) 1991-09-04
AU629453B2 (en) 1992-10-01
IL97306A0 (en) 1992-05-25
DE69112099T2 (de) 1996-02-08
CA2037099C (en) 2001-09-11

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