PT89029A - Processo para a preparacao de novos derivados substituidos de 20,21-dinoreburnamenina - Google Patents

Processo para a preparacao de novos derivados substituidos de 20,21-dinoreburnamenina

Info

Publication number
PT89029A
PT89029A PT89029A PT8902988A PT89029A PT 89029 A PT89029 A PT 89029A PT 89029 A PT89029 A PT 89029A PT 8902988 A PT8902988 A PT 8902988A PT 89029 A PT89029 A PT 89029A
Authority
PT
Portugal
Prior art keywords
doreurburnamenine
derivatives
preparation
new substituted
compound
Prior art date
Application number
PT89029A
Other languages
English (en)
Other versions
PT89029B (pt
Inventor
Nurguen Aktogu
Francois Clemence
Claude Oberlander
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of PT89029A publication Critical patent/PT89029A/pt
Publication of PT89029B publication Critical patent/PT89029B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Peptides Or Proteins (AREA)
  • Indole Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT89029A 1987-11-19 1988-11-18 Processo para a preparacao de novos derivados substituidos de 20,21-dinoreburnamenina PT89029B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8715980A FR2623501B1 (fr) 1987-11-19 1987-11-19 Nouveaux derives substitues de 20,21-dinoreburnamenine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions pharmaceutiques les renfermant

Publications (2)

Publication Number Publication Date
PT89029A true PT89029A (pt) 1988-12-01
PT89029B PT89029B (pt) 1993-02-26

Family

ID=9356933

Family Applications (1)

Application Number Title Priority Date Filing Date
PT89029A PT89029B (pt) 1987-11-19 1988-11-18 Processo para a preparacao de novos derivados substituidos de 20,21-dinoreburnamenina

Country Status (16)

Country Link
US (2) US5093337A (pt)
EP (1) EP0317427B1 (pt)
JP (1) JP2694553B2 (pt)
KR (1) KR970005299B1 (pt)
AT (1) ATE100102T1 (pt)
AU (1) AU621074B2 (pt)
CA (1) CA1332735C (pt)
DE (1) DE3887102T2 (pt)
ES (1) ES2061712T3 (pt)
FR (1) FR2623501B1 (pt)
HU (2) HU204824B (pt)
PT (1) PT89029B (pt)
RU (1) RU2043353C1 (pt)
UA (1) UA26443A (pt)
WO (1) WO1989004830A1 (pt)
ZA (1) ZA888663B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2653124B1 (fr) * 1989-10-17 1992-01-17 Roussel Uclaf Nouveaux derives substitues en 15 de la 20, 21-dinoreburnamenine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions les renfermant.
CA2036337C (fr) * 1990-02-15 2003-04-15 Francois Clemence Derives de la 20,21-dinoreburnamenine, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions les renfermant
FR2731154B1 (fr) * 1995-03-03 1997-05-09 Roussel Uclaf Compositions pharmaceutiques comprenant des derives de dinoreburnamenine
FR2865649A1 (fr) * 2004-01-30 2005-08-05 Biocortech Utilisation du 14,15-dihydro 20,21-dinoreburnamenin14-ol pour traiter et/ou prevenir les depressions majeures
FR2865650B1 (fr) * 2004-01-30 2008-06-13 Biocortech Utilisation du 14,15 dihydro 20,21-dinoreburnamenin14-ol pour traiter et/ou prevenir les depressions majeures et les desordres du cycle veille-sommeil
FR2869034B1 (fr) * 2004-04-14 2008-04-04 Biocortech Soc Par Actions Sim Derive du 14,15-dihydro 20,21-dinoreburnamenin 14-ol et leur utilisation pour le traitement des depressions

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2081587B1 (pt) * 1970-03-26 1973-04-06 Anvar
DE2538095A1 (de) * 1974-09-06 1976-03-25 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
FR2339618A1 (fr) * 1976-01-30 1977-08-26 Omnium Chimique Sa Procede de preparation de (-)11-aminovincamone, de 11-aminoeburamonine, de 11-aminovincamone racemique et derives indoliques nouveaux
DE2703920A1 (de) * 1976-02-05 1977-08-11 Sandoz Ag Neue organische verbindungen, ihre herstellung und verwendung
FR2381048A1 (fr) * 1977-02-22 1978-09-15 Roussel Uclaf Nouveaux derives de 20,21-dinoreburnamenine, un procede pour leur preparation et leur application comme medicaments
HU180929B (en) * 1979-08-13 1983-05-30 Richter Gedeon Vegyeszet Process for producing new bromo-vincamone derivatives
HU183594B (en) * 1981-09-30 1984-05-28 Richter Gedeon Vegyeszet Process for producing 11-methoxy-vincamone
FR2514357A1 (fr) * 1981-10-08 1983-04-15 Roussel Uclaf Nouveaux derives de 20,21-dinoreburnamenine eventuellement substitues sur le cycle e, procede de preparation et application comme medicaments
HU191403B (en) * 1984-04-02 1987-02-27 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for preparing new, raceme and optically active 14-hydroxyimino-eburnane
HU191694B (en) * 1984-07-11 1987-03-30 Richter Gedeon Vegyeszet Process for production of new derivatives of amineburnan carbonic acid
HU198207B (en) * 1985-04-19 1989-08-28 Richter Gedeon Vegyeszet Process for production of derivatives of eburnamenin and medical compositions containing them
ES8604957A1 (es) * 1985-11-28 1986-03-16 Covex Sa Procedimiento para la preparacion del (+n-) 14,15-dihidro- (3b,14x,16x)-20,21-dinoreburnamenin-14-ol
FR2623503B1 (pt) * 1987-11-19 1991-04-05 Roussel Uclaf

Also Published As

Publication number Publication date
US5093337A (en) 1992-03-03
HU886767D0 (en) 1990-09-28
HU204824B (en) 1992-02-28
UA26443A (uk) 1999-08-30
CA1332735C (fr) 1994-10-25
HUT53103A (en) 1990-09-28
FR2623501A1 (fr) 1989-05-26
JP2694553B2 (ja) 1997-12-24
FR2623501B1 (fr) 1990-03-16
EP0317427A1 (fr) 1989-05-24
JPH02502187A (ja) 1990-07-19
PT89029B (pt) 1993-02-26
ATE100102T1 (de) 1994-01-15
ES2061712T3 (es) 1994-12-16
HU211589A9 (en) 1995-12-28
KR890701584A (ko) 1989-12-21
AU621074B2 (en) 1992-03-05
ZA888663B (en) 1990-01-31
DE3887102D1 (de) 1994-02-24
AU2729588A (en) 1989-06-14
EP0317427B1 (fr) 1994-01-12
US5332748A (en) 1994-07-26
DE3887102T2 (de) 1994-05-05
WO1989004830A1 (fr) 1989-06-01
RU2043353C1 (ru) 1995-09-10
KR970005299B1 (ko) 1997-04-15

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Legal Events

Date Code Title Description
FG3A Patent granted, date of granting

Effective date: 19920828

PC3A Transfer or assignment

Free format text: 19991011 HOECHST MARION ROUSSEL FR

PD3A Change of proprietorship

Owner name: ROUSSEL UCLAF

Effective date: 19991011

TE3A Change of address (patent)

Owner name: ROUSSEL UCLAF

Effective date: 19991011

PC3A Transfer or assignment

Free format text: AVENTIS PHARMA S.A. FR

Effective date: 20030110

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20040229