PT97680A - Processo para preparacao de novos compostos sulfonilo e de composicoes farmaceuticas que os contem - Google Patents

Processo para preparacao de novos compostos sulfonilo e de composicoes farmaceuticas que os contem

Info

Publication number
PT97680A
PT97680A PT97680A PT9768091A PT97680A PT 97680 A PT97680 A PT 97680A PT 97680 A PT97680 A PT 97680A PT 9768091 A PT9768091 A PT 9768091A PT 97680 A PT97680 A PT 97680A
Authority
PT
Portugal
Prior art keywords
formula
pct
preparation
new compounds
date nov
Prior art date
Application number
PT97680A
Other languages
English (en)
Other versions
PT97680B (pt
Inventor
Kurt Klemm
Dieter Flockerzi
Hermann Amschler
Volker Figala
Rolf Beume
Dietrich Hafner
Guido Hanauer
Manfried Eltze
Christian Schudt
Ulrich Kilian
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of PT97680A publication Critical patent/PT97680A/pt
Publication of PT97680B publication Critical patent/PT97680B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
PT97680A 1990-05-16 1991-05-15 Processo para preparacao de novos compostos sulfonilo e de composicoes farmaceuticas que os contem PT97680B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH165890 1990-05-16

Publications (2)

Publication Number Publication Date
PT97680A true PT97680A (pt) 1992-02-28
PT97680B PT97680B (pt) 1998-09-30

Family

ID=4215610

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97680A PT97680B (pt) 1990-05-16 1991-05-15 Processo para preparacao de novos compostos sulfonilo e de composicoes farmaceuticas que os contem

Country Status (23)

Country Link
US (1) US5346904A (pt)
EP (1) EP0528922B1 (pt)
JP (1) JP3238397B2 (pt)
CN (1) CN1027507C (pt)
AT (1) ATE181330T1 (pt)
AU (1) AU651592B2 (pt)
CA (1) CA2082923C (pt)
CS (1) CS144791A3 (pt)
DE (3) DE4191109A1 (pt)
DK (1) DK0528922T3 (pt)
ES (1) ES2134777T3 (pt)
FI (1) FI925005A0 (pt)
GR (1) GR3031098T3 (pt)
HU (2) HUT62895A (pt)
IE (1) IE911625A1 (pt)
IL (1) IL98133A (pt)
MY (1) MY105344A (pt)
NO (1) NO924414D0 (pt)
NZ (1) NZ238141A (pt)
PT (1) PT97680B (pt)
WO (1) WO1991017991A1 (pt)
YU (1) YU85691A (pt)
ZA (1) ZA913627B (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0612247A1 (de) * 1991-11-15 1994-08-31 Byk Gulden Lomberg Chemische Fabrik GmbH Verwendung von sulfonylverbindungen
US5958926A (en) * 1996-11-01 1999-09-28 Nitromed, Inc. Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses
DE69719778T2 (de) * 1996-11-11 2004-02-05 Altana Pharma Ag Benzonaphthyridine als bronchialtherapeutika
WO1998040382A1 (en) * 1997-03-07 1998-09-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel tetrazoles
EP0988302B1 (en) 1997-06-03 2003-02-19 ALTANA Pharma AG Benzonaphthyridines
DE69828284T2 (de) 1997-06-30 2005-12-08 Nippon Kayaku K.K. Naphthyridinderivate oder salze davon
PL200923B1 (pl) 1999-08-21 2009-02-27 Nycomed Gmbh Lek zawierający inhibitor PDE w połączeniu z agonistą receptoraß₂ -adrenergicznego oraz zastosowanie połączenia roflumilastu i salmeterolu
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
CA2517487A1 (en) 2003-04-01 2004-10-14 Applied Research Systems Ars Holding N.V. Inhibitors of phosphodiesterases in infertility
EA020466B1 (ru) 2007-06-04 2014-11-28 Синерджи Фармасьютикалз Инк. Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
JP2011522828A (ja) 2008-06-04 2011-08-04 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
CA2730603C (en) 2008-07-16 2019-09-24 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8196556B2 (en) * 2009-09-17 2012-06-12 Delphi Technologies, Inc. Apparatus and method for setting mechanical lash in a valve-deactivating hydraulic lash adjuster
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2828346C (en) 2011-03-01 2021-01-26 Synergy Pharmaceuticals Inc. Process of preparing guanylate cyclase c agonists
AU2014218599C1 (en) 2013-02-25 2018-09-06 Bausch Health Ireland Limited Guanylate cyclase receptor agonists for use in colonic cleansing
AU2014235215A1 (en) 2013-03-15 2015-10-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
KR102272746B1 (ko) 2013-06-05 2021-07-08 보슈 헬스 아일랜드 리미티드 구아닐레이트 사이클라제 c의 초순수 작용제, 및 이의 제조 및 사용 방법
MX2016001714A (es) 2013-08-09 2016-10-03 Ardelyx Inc Compuestos y metodos para inhibir el transporte de fosfato.
JP2022533251A (ja) 2019-05-21 2022-07-21 アルデリックス， インコーポレイテッド 患者において血清リン酸塩を低下させるための組み合わせ

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899494A (en) * 1970-05-13 1975-08-12 Sandoz Ltd Substituted 6-phenyl benzo-naphthyridines
US4087530A (en) * 1974-02-05 1978-05-02 Sandoz Ltd. Substituted 6-phenyl-octahydrobenzo [c] [1,6] naphthyridines
DK136189B (da) * 1974-02-05 1977-08-29 Sandoz Ag Analogifremgangsmåde til fremstilling af benzo(c)(1,6)naphthyridinderivater eller syreadditionssalte deraf.
EP0247971A3 (en) * 1986-05-29 1990-01-17 Sandoz Ag Novel pharmaceutical compositions comprising and use of cis-6-(4-acetanilido)-8,9-dimethoxy-2-methyl-1,2,3,4,4a,10b-hexahydrobenzo[c][1,6]naphthyridin

Also Published As

Publication number Publication date
CA2082923C (en) 2001-12-18
WO1991017991A1 (de) 1991-11-28
DE4191109A1 (pt) 1993-04-01
DE59109135D1 (de) 1999-07-22
CA2082923A1 (en) 1991-11-17
EP0528922B1 (de) 1999-06-16
AU7870191A (en) 1991-12-10
FI925005A (fi) 1992-11-05
IL98133A0 (en) 1992-06-21
ES2134777T3 (es) 1999-10-16
HUT62895A (en) 1993-06-28
US5346904A (en) 1994-09-13
EP0528922A1 (de) 1993-03-03
MY105344A (en) 1994-09-30
NO924414L (no) 1992-11-16
CN1027507C (zh) 1995-01-25
FI925005A0 (fi) 1992-11-05
NZ238141A (en) 1993-07-27
IE911625A1 (en) 1991-11-20
JPH05507081A (ja) 1993-10-14
JP3238397B2 (ja) 2001-12-10
ZA913627B (en) 1992-01-29
PT97680B (pt) 1998-09-30
YU85691A (sh) 1994-06-24
NO924414D0 (no) 1992-11-16
GR3031098T3 (en) 1999-12-31
DE4191109D2 (en) 1993-04-01
ATE181330T1 (de) 1999-07-15
CS144791A3 (en) 1992-03-18
AU651592B2 (en) 1994-07-28
DK0528922T3 (da) 1999-11-22
IL98133A (en) 1994-11-11
CN1056691A (zh) 1991-12-04
HU9203557D0 (en) 1993-03-29

Similar Documents

Publication Publication Date Title
PT97680A (pt) Processo para preparacao de novos compostos sulfonilo e de composicoes farmaceuticas que os contem
BR9406362A (pt) Composto,processo para a preparação do mesmo e composição anti-nuclear
ES2194987T3 (es) Compuestos triciclicos utiles para inhibir la farnesil-protein-transferasa.
ES552627A0 (es) Procedimiento para la preparacion de carbamatos de fenilo
ES2170813T3 (es) Acidos 2,2-dicloroalcanocarboxilicos, proceso para su preparacion, medicamentos que los contienen y su uso para tratar la resistencia a la insulina.
PT83961B (pt) Processo para a preparacao de derivados da pirazolina e de composicoes insecticidas e acaricidas que os contem
BR9509970A (pt) Composto
FI853624A0 (fi) 1-substituerade tetralinderivat, deras framstaellning och anvaendning.
BR8305838A (pt) Composicao herbicidas, contendo derivados de ciclohexano - 1,3 - diona, e processo para preparacao destes derivados
FI860426A (fi) Primycinkomponenter samt foerfarande foer avskiljning av antibiotkomplex.
ATE163402T1 (de) Substituierte ortho- ethenylphenylessigsäurederivate
ES2065039T3 (es) Procedimiento para la preparacion de 10-g(b)-h-esteroides.
PT94685A (pt) Processo para a preparacao de 2-imidazolinas substituidas e de composicoes farmaceuticas que as contem
PT98268A (pt) Processo para a preparacao de indano-pirrolidino-carbamatos
BR9507623A (pt) Composto processo e precursor para á preparação do mesmo
ES2140683T3 (es) Procedimiento para preparar compuestos de benzopirano.
ES2053686T3 (es) Nuevos di(met)acrilatos, procedimiento para su fabricacion y su empleo.
ES2106866T3 (es) Nuevos derivados de 2h-benzo(b)pirano sustituidos en la posicion 4 por arilo o n-heteroarilo, procedimiento para su preparacion y su uso, asi como preparados que contienen los compuestos.
FI925444A (fi) Utgaongsaemnen foer framstaellning av 10b-h-steroider och framstaellning avdessa utgaongsaemnen
ES2038799T3 (es) Derivados de 3-ciano-4-fenil-pirrol.
BR8100174A (pt) Composicoes pesticidas, e, processo para preparar n-metil-n-silil-carbamatos, aplicaveis nas mesmas
BR8206677A (pt) Processo para a preparacao de alquilcicloalquil-imidazolil-meril-cetonas e aplicacao
ES2098119T3 (es) Nuevas triazoloquinazolinas, su obtencion y empleo.
YU47836B (sr) Postupak za pravljenje pirimidintrionskih derivata
ES2171255T3 (es) Nuevos compuestos intermedios para plaguicidas.

Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19911029

FG3A Patent granted, date of granting

Effective date: 19980616

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19991231

NF3A Restitutio in integrum

Free format text: 20000517 RESTITUTIO IN INTEGRUM

PD3A Change of proprietorship

Free format text: ALTANA PHARMA AG DE

Effective date: 20021217

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20101216