DK0528922T3 - Hidtil ukendte sulfonylforbindelser - Google Patents

Hidtil ukendte sulfonylforbindelser

Info

Publication number
DK0528922T3
DK0528922T3 DK91909549T DK91909549T DK0528922T3 DK 0528922 T3 DK0528922 T3 DK 0528922T3 DK 91909549 T DK91909549 T DK 91909549T DK 91909549 T DK91909549 T DK 91909549T DK 0528922 T3 DK0528922 T3 DK 0528922T3
Authority
DK
Denmark
Prior art keywords
pct
sulfonyl compounds
date nov
new sulfonyl
sec
Prior art date
Application number
DK91909549T
Other languages
English (en)
Inventor
Dieter Flockerzi
Kurt Klemm
Hermann Amschler
Volker Figala
Rolf Beume
Dietrich Haefner
Guido Hanauer
Manfrid Eltze
Christian Schudt
Ulrich Kilian
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Application granted granted Critical
Publication of DK0528922T3 publication Critical patent/DK0528922T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heat Treatment Of Steel (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK91909549T 1990-05-16 1991-05-14 Hidtil ukendte sulfonylforbindelser DK0528922T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH165890 1990-05-16
PCT/EP1991/000895 WO1991017991A1 (de) 1990-05-16 1991-05-14 Neue sulfonylverbindungen

Publications (1)

Publication Number Publication Date
DK0528922T3 true DK0528922T3 (da) 1999-11-22

Family

ID=4215610

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91909549T DK0528922T3 (da) 1990-05-16 1991-05-14 Hidtil ukendte sulfonylforbindelser

Country Status (23)

Country Link
US (1) US5346904A (da)
EP (1) EP0528922B1 (da)
JP (1) JP3238397B2 (da)
CN (1) CN1027507C (da)
AT (1) ATE181330T1 (da)
AU (1) AU651592B2 (da)
CA (1) CA2082923C (da)
CS (1) CS144791A3 (da)
DE (3) DE4191109A1 (da)
DK (1) DK0528922T3 (da)
ES (1) ES2134777T3 (da)
FI (1) FI925005A (da)
GR (1) GR3031098T3 (da)
HU (2) HU9203557D0 (da)
IE (1) IE911625A1 (da)
IL (1) IL98133A (da)
MY (1) MY105344A (da)
NO (1) NO924414D0 (da)
NZ (1) NZ238141A (da)
PT (1) PT97680B (da)
WO (1) WO1991017991A1 (da)
YU (1) YU85691A (da)
ZA (1) ZA913627B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993009780A1 (de) * 1991-11-15 1993-05-27 Byk Gulden Lomberg Chemische Fabrik Gmbh Verwendung von sulfonylverbindungen
US5958926A (en) * 1996-11-01 1999-09-28 Nitromed, Inc. Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses
NZ334976A (en) * 1996-11-11 2000-10-27 Byk Gulden Lomberg Chem Fab Benzonaphthyridine derivatives and their use for treating airway disorders and dermatoses
AU6825898A (en) * 1997-03-07 1998-09-29 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel tetrazoles
US6384047B1 (en) 1997-06-03 2002-05-07 Byk Gulden Lomberg Chemische Fabrik Gmbh Benzonaphthyridine
PL337672A1 (en) 1997-06-30 2000-08-28 Nippon Kayaku Kk Novel derivatives of naphtyridine or their salts
EP2193808A1 (en) 1999-08-21 2010-06-09 Nycomed GmbH Synergistic combination
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
EA200501548A1 (ru) 2003-04-01 2006-02-24 Апплайд Резеч Системз Арс Холдинг Н.В. Ингибиторы фосфодиэстераз при бесплодии
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EA020466B1 (ru) 2007-06-04 2014-11-28 Синерджи Фармасьютикалз Инк. Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний
CA2726917C (en) 2008-06-04 2018-06-26 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CA2730603C (en) 2008-07-16 2019-09-24 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8196556B2 (en) * 2009-09-17 2012-06-12 Delphi Technologies, Inc. Apparatus and method for setting mechanical lash in a valve-deactivating hydraulic lash adjuster
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
WO2012118972A2 (en) 2011-03-01 2012-09-07 Synegy Pharmaceuticals Inc. Process of preparing guanylate cyclase c agonists
WO2014131024A2 (en) 2013-02-25 2014-08-28 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
CN113388007A (zh) 2013-06-05 2021-09-14 博士医疗爱尔兰有限公司 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
MX2016001714A (es) 2013-08-09 2016-10-03 Ardelyx Inc Compuestos y metodos para inhibir el transporte de fosfato.
US20200368223A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Methods for inhibiting phosphate transport

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899494A (en) * 1970-05-13 1975-08-12 Sandoz Ltd Substituted 6-phenyl benzo-naphthyridines
US4087530A (en) * 1974-02-05 1978-05-02 Sandoz Ltd. Substituted 6-phenyl-octahydrobenzo [c] [1,6] naphthyridines
SE7500859L (da) * 1974-02-05 1975-08-06 Sandoz Ag
EP0247971A3 (en) * 1986-05-29 1990-01-17 Sandoz Ag Novel pharmaceutical compositions comprising and use of cis-6-(4-acetanilido)-8,9-dimethoxy-2-methyl-1,2,3,4,4a,10b-hexahydrobenzo[c][1,6]naphthyridin

Also Published As

Publication number Publication date
FI925005A0 (fi) 1992-11-05
MY105344A (en) 1994-09-30
HUT62895A (en) 1993-06-28
HU9203557D0 (en) 1993-03-29
DE4191109A1 (da) 1993-04-01
DE59109135D1 (de) 1999-07-22
EP0528922A1 (de) 1993-03-03
EP0528922B1 (de) 1999-06-16
IL98133A0 (en) 1992-06-21
IE911625A1 (en) 1991-11-20
NZ238141A (en) 1993-07-27
FI925005A (fi) 1992-11-05
PT97680A (pt) 1992-02-28
AU7870191A (en) 1991-12-10
ZA913627B (en) 1992-01-29
CN1056691A (zh) 1991-12-04
IL98133A (en) 1994-11-11
CA2082923C (en) 2001-12-18
DE4191109D2 (en) 1993-04-01
CN1027507C (zh) 1995-01-25
GR3031098T3 (en) 1999-12-31
ATE181330T1 (de) 1999-07-15
PT97680B (pt) 1998-09-30
JPH05507081A (ja) 1993-10-14
NO924414L (no) 1992-11-16
NO924414D0 (no) 1992-11-16
AU651592B2 (en) 1994-07-28
CA2082923A1 (en) 1991-11-17
CS144791A3 (en) 1992-03-18
US5346904A (en) 1994-09-13
YU85691A (sh) 1994-06-24
ES2134777T3 (es) 1999-10-16
JP3238397B2 (ja) 2001-12-10
WO1991017991A1 (de) 1991-11-28

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Legal Events

Date Code Title Description
ATS Application withdrawn