YU44918B - Process for preparing derivatives of s(-)pyridobenzoxazine - Google Patents

Process for preparing derivatives of s(-)pyridobenzoxazine

Info

Publication number
YU44918B
YU44918B YU1073/86A YU107386A YU44918B YU 44918 B YU44918 B YU 44918B YU 1073/86 A YU1073/86 A YU 1073/86A YU 107386 A YU107386 A YU 107386A YU 44918 B YU44918 B YU 44918B
Authority
YU
Yugoslavia
Prior art keywords
pyridobenzoxazine
preparing
optically active
derivative
preparing derivatives
Prior art date
Application number
YU1073/86A
Other languages
English (en)
Other versions
YU107386A (en
Inventor
I Hayakawa
S Atarashi
S Yokohama
M Imamura
K Sakano
N Higashihashi
M Ohshima
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27281433&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=YU44918(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from JP60226499A external-priority patent/JPH0720946B2/ja
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Priority to SI8611073A priority Critical patent/SI8611073A8/sl
Publication of YU107386A publication Critical patent/YU107386A/xx
Publication of YU44918B publication Critical patent/YU44918B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
YU1073/86A 1985-06-20 1986-06-19 Process for preparing derivatives of s(-)pyridobenzoxazine YU44918B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SI8611073A SI8611073A8 (sl) 1985-06-20 1986-06-19 Postopek za pripravo derivata s(-)-piridobenzoksazina

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP13471285 1985-06-20
JP60226499A JPH0720946B2 (ja) 1985-10-11 1985-10-11 光学活性３−メチルベンゾオキサジン誘導体およびその製法
JP1649686 1986-01-28

Publications (2)

Publication Number Publication Date
YU107386A YU107386A (en) 1988-02-29
YU44918B true YU44918B (en) 1991-04-30

Family

ID=27281433

Family Applications (3)

Application Number Title Priority Date Filing Date
YU1073/86A YU44918B (en) 1985-06-20 1986-06-19 Process for preparing derivatives of s(-)pyridobenzoxazine
YU1867/88A YU45512B (en) 1985-06-20 1988-10-05 Opticaly active derivative of benzoxazine
YU2098/89A YU45524B (en) 1985-06-20 1989-10-30 Process for preparing derivatives of s(-)-pyridobenzoxazine

Family Applications After (2)

Application Number Title Priority Date Filing Date
YU1867/88A YU45512B (en) 1985-06-20 1988-10-05 Opticaly active derivative of benzoxazine
YU2098/89A YU45524B (en) 1985-06-20 1989-10-30 Process for preparing derivatives of s(-)-pyridobenzoxazine

Country Status (16)

Country Link
US (3) US5053407A (nl)
EP (1) EP0206283B1 (nl)
KR (2) KR920010048B1 (nl)
AT (1) ATE85057T1 (nl)
BG (1) BG60527B2 (nl)
CA (1) CA1304080C (nl)
DE (2) DE3687599T2 (nl)
DK (1) DK170473B1 (nl)
ES (1) ES8801251A1 (nl)
FI (1) FI90241C (nl)
GR (1) GR861625B (nl)
HK (1) HK91793A (nl)
IE (1) IE59463B1 (nl)
NL (1) NL980016I2 (nl)
NO (1) NO166131C (nl)
YU (3) YU44918B (nl)

Families Citing this family (58)

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EP0273399B1 (en) * 1986-12-25 1994-08-17 Daiichi Pharmaceutical Co., Ltd. Optically active 2,3-dihydrobenzoaxine derivatives and process for preparing the same
NO172846C (no) * 1987-12-25 1993-09-15 Daiichi Seiyaku Co Fremgangsmaate for fremstilling av 7,8-dihalogen-3-metyl-2,3-dihydro-2m-benzoksazinderivater og propoksybenzenderivater for utoevelse av fremgangsmaaten.
US5175160A (en) * 1988-08-09 1992-12-29 Daiichi Pharmaceutical Co., Ltd. Antimicrobial agent for animals
MY104139A (en) * 1988-08-09 1994-02-28 Daiichi Seiyaku Co Antimicrobial agent for animals
AU4376589A (en) * 1988-11-07 1990-05-10 Gist-Brocades N.V. Optically active benzoxazines and benzothiazines
FI94339C (fi) 1989-07-21 1995-08-25 Warner Lambert Co Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
FR2655545B1 (fr) * 1989-12-11 1994-06-10 Rhone Poulenc Sante Nouvelle application therapeutique des derives des fluoroquinolones.
TW208013B (nl) * 1990-03-01 1993-06-21 Daiichi Co Ltd
NO179912C (no) * 1990-11-28 1997-01-08 Daiichi Seiyaku Co Analogifremgangsmåte for fremstilling av et terapeutisk virksomt optisk aktivt pyridobenzoksazinderivat
ES2055656B1 (es) * 1992-10-07 1995-11-16 Etilo Derivados Procedimiento para la obtencion de benzoxazinas utiles para sintesis de ofloxacina, levofloxacina y derivados.
AU674542B2 (en) * 1992-10-07 1997-01-02 Derivados Del Etilo, S.A. Process for obtaining benzoxazines useful for the synthesis of ofloxacin, levofloxacin and derivatives thereof
US5532239A (en) * 1993-08-02 1996-07-02 Assistance Publique - Hopitaux De Paris Therapeutic application of fluoroquinolone derivatives
ZA946853B (en) * 1993-09-10 1995-04-24 Daiichi Seiyaku Co Crystals of antimicrobial compound.
US5686095A (en) * 1995-10-23 1997-11-11 Price, Jr.; Francis W. Method of treating canker sores
CN1094757C (zh) 1996-07-24 2002-11-27 沃尼尔·朗伯公司 用于治疗疼痛的异丁基γ－氨基丁酸及其衍生物
US6248343B1 (en) 1998-01-20 2001-06-19 Ethicon, Inc. Therapeutic antimicrobial compositions
US6022551A (en) * 1998-01-20 2000-02-08 Ethicon, Inc. Antimicrobial composition
US5972358A (en) * 1998-01-20 1999-10-26 Ethicon, Inc. Low tack lotion, gels and creams
US5997893A (en) * 1998-01-20 1999-12-07 Ethicon, Inc. Alcohol based anti-microbial compositions with cosmetic appearance
KR100309871B1 (ko) 1999-02-24 2001-10-29 윤종용 (-)피리도벤즈옥사진 카르복실산 유도체의 제조방법
IL143535A0 (en) 1998-12-04 2002-04-21 Influx Inc Inhibitors of multidrug transporters
KR100617952B1 (ko) * 1999-03-04 2006-08-30 보령제약 주식회사 광학활성 피리도 벤즈옥사진 유도체의 제조방법
CA2660917C (en) * 1999-09-08 2012-01-03 Daiichi Sankyo Company, Limited Process for producing benzoxazine derivative and production intermediate thereof
KR20010103346A (ko) * 2000-05-09 2001-11-23 이후근 패각 입자와 접착제 그리고 물감을 혼합하여 그림 밑칠용재료를 제조하는 방법
WO2002059116A2 (en) 2000-12-21 2002-08-01 Pharmacia & Upjohn Company Antimicrobial quinolone derivatives and use of the same to treat bacterial infections
JP4169332B2 (ja) * 2001-03-07 2008-10-22 第一三共株式会社 光学活性なプロポキシアニリン誘導体の製造方法
CN1201028C (zh) 2001-04-27 2005-05-11 浦项产业科学研究院 具有优越热加工性能的高锰二联不锈钢及其制造方法
US7425628B2 (en) * 2001-10-03 2008-09-16 Teva Pharmaceutical Industries Ltd. Methods for the purification of levofloxacin
US7629458B2 (en) 2001-10-03 2009-12-08 Teva Pharmaceutical Industries Ltd. Preparation of levofloxacin and hemihydrate thereof
KR100440192B1 (ko) * 2001-11-22 2004-07-12 이수화학 주식회사 광학 활성 퀴놀론카르복실산 유도체의 제조방법
WO2003045329A2 (en) * 2001-11-29 2003-06-05 Teva Pharmaceutical Industries Ltd. Methods for the purification of levofloxacin
US20040052843A1 (en) * 2001-12-24 2004-03-18 Lerner E. Itzhak Controlled release dosage forms
NZ534104A (en) * 2001-12-24 2007-03-30 Teva Pharma Dosage form with a core tablet of active ingredient sheathed in a compressed annular body of powder or granular material
AU2003217676B2 (en) 2002-02-22 2009-06-11 Takeda Pharmaceutical Company Limited Active agent delivery systems and methods for protecting and administering active agents
AU2003262704A1 (en) * 2002-08-14 2004-08-30 Teva Pharmaceutical Industries Ltd. Synthesis of gatifloxacin
US20040152701A1 (en) * 2002-12-02 2004-08-05 Dr. Reddy's Laboratories Limited Novel anhydrous crystalline form of Levofloxacin and process for preparation there of
FR2859471B1 (fr) 2003-09-09 2006-02-03 Solvay Procede pour la fabrication d'un compose enantiopur
CN101119986B (zh) 2005-02-07 2011-07-06 田边三菱制药株式会社 光学活性四氢萘衍生物
US7838532B2 (en) * 2005-05-18 2010-11-23 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
US8524734B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
US20090264342A1 (en) * 2006-02-13 2009-10-22 Trustees Of Boston University Compositions and methods for antibiotic potentiation and drug discovery
US20070197548A1 (en) 2006-02-17 2007-08-23 Murthy Yerramilli V S Fluoroquinolone compositions
US7973022B2 (en) 2006-02-17 2011-07-05 Idexx Laboratories, Inc. Fluoroquinolone carboxylic acid salt compositions
US20100234348A1 (en) * 2006-08-04 2010-09-16 Trustees Of Boston University Compositions and methods for potentiating antibiotic activity
EP1939206A1 (en) * 2006-12-22 2008-07-02 Farmaprojects, S.A. Process for the preparation of an antibacterial quinolone compound
US20100029938A1 (en) * 2006-12-22 2010-02-04 Farmaprojects, S. A. Process for the preparation of an antibacterial quinolone compound
US7964723B2 (en) 2008-08-02 2011-06-21 Apeloa-Kangyu And practical process for exclusively producing (S)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido-[1,2,3,de][1,4]benzoxazine-6-carboxylic acid hemihydrate
EP2346509B1 (en) 2008-10-07 2020-05-13 Horizon Orphan LLC Inhalation of levofloxacin for reducing lung inflammation
PL2344129T3 (pl) 2008-10-07 2018-07-31 Horizon Orphan Llc Formulacje fluorochinolonu w aerozolu dla poprawy właściwości farmakokinetycznych
CN102459169B (zh) 2009-05-15 2014-12-31 莱德克斯制药有限公司 氧化还原药物衍生物
AU2010289326B2 (en) 2009-09-04 2015-09-24 Horizon Therapeutics U.S. Holding Llc Use of aerosolized levofloxacin for treating cystic fibrosis
CN101659669B (zh) * 2009-09-04 2011-07-20 诚达药业股份有限公司 左旋氧氟沙星的制备方法
CN102775424A (zh) * 2012-07-09 2012-11-14 浙江司太立制药股份有限公司 一种左氧氟沙星杂质的制备方法
BR112015023044A8 (pt) 2013-03-15 2021-09-28 Melinta Subsidiary Corp Métodos para tratar infecções em pacientes acima do peso e obesos com o uso de antibióticos
TN2016000495A1 (en) * 2014-05-09 2018-04-04 Tecnimede Sociedade Tecnico Medicinal S Pharmaceutically acceptable salts of pirlindole enantiomers for use in medicine.
CN105037388A (zh) * 2015-08-28 2015-11-11 安徽环球药业股份有限公司 一种安妥沙星的制备方法
CN105367585B (zh) * 2015-12-02 2017-11-17 山东齐都药业有限公司 左氧氟沙星杂质的制备方法
EP4149427A1 (en) 2020-06-11 2023-03-22 Sentiss Pharma Private Limited Ophthalmic compositions comprising a combination of fluoroquinolone antibacterial agent and an anti-inflammatory agent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5746986A (en) * 1980-09-02 1982-03-17 Dai Ichi Seiyaku Co Ltd Pyrido(1,2,3-de)(1,4)benzoxazine derivative
JPS5852290A (ja) * 1981-09-21 1983-03-28 Dai Ichi Seiyaku Co Ltd ピリドベンゾオキサジンカルボン酸誘導体
DE3543513A1 (de) * 1985-12-10 1987-06-11 Bayer Ag Enantiomerenreine 1,8-verbrueckte 4-chinolon-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende arzneimittel und ihre verwendung zur herstellung von arzneimitteln

Also Published As

Publication number Publication date
NO862426D0 (no) 1986-06-18
NO862426L (no) 1986-12-22
BG60527B2 (bg) 1995-07-28
YU186788A (en) 1989-04-30
KR940003757B1 (ko) 1994-04-30
FI862643A0 (fi) 1986-06-19
ES8801251A1 (es) 1988-01-01
DK170473B1 (da) 1995-09-11
DK285086A (da) 1986-12-21
YU45512B (en) 1992-05-28
YU107386A (en) 1988-02-29
KR920009279A (ko) 1992-05-28
US5142046A (en) 1992-08-25
GR861625B (en) 1986-10-21
NO166131B (no) 1991-02-25
ATE85057T1 (de) 1993-02-15
NO166131C (no) 1991-06-05
ES556292A0 (es) 1988-01-01
CA1304080C (en) 1992-06-23
FI90241C (fi) 1994-01-10
YU45524B (en) 1992-05-28
IE59463B1 (en) 1994-02-23
EP0206283B1 (en) 1993-01-27
HK91793A (en) 1993-09-10
DK285086D0 (da) 1986-06-18
NL980016I2 (nl) 1998-08-03
US4985557A (en) 1991-01-15
KR920010048B1 (ko) 1992-11-13
US5053407A (en) 1991-10-01
FI90241B (fi) 1993-09-30
EP0206283A3 (en) 1988-08-10
KR870000340A (ko) 1987-02-17
IE861631L (en) 1986-12-20
DE3687599D1 (de) 1993-03-11
YU209889A (en) 1990-04-30
NL980016I1 (nl) 1998-07-01
DE3687599T2 (de) 1993-05-19
FI862643A (fi) 1986-12-21
EP0206283A2 (en) 1986-12-30
DE19875012I2 (de) 2006-06-29

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