HK91793A - Optically active pyridobenzoxazine derivatives - Google Patents
Optically active pyridobenzoxazine derivativesInfo
- Publication number
- HK91793A HK91793A HK917/93A HK91793A HK91793A HK 91793 A HK91793 A HK 91793A HK 917/93 A HK917/93 A HK 917/93A HK 91793 A HK91793 A HK 91793A HK 91793 A HK91793 A HK 91793A
- Authority
- HK
- Hong Kong
- Prior art keywords
- optically active
- preparing
- active pyridobenzoxazine
- derivatives
- pyridobenzoxazine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13471285 | 1985-06-20 | ||
JP60226499A JPH0720946B2 (ja) | 1985-10-11 | 1985-10-11 | 光学活性3−メチルベンゾオキサジン誘導体およびその製法 |
JP1649686 | 1986-01-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK91793A true HK91793A (en) | 1993-09-10 |
Family
ID=27281433
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK917/93A HK91793A (en) | 1985-06-20 | 1993-09-02 | Optically active pyridobenzoxazine derivatives |
Country Status (16)
Country | Link |
---|---|
US (3) | US5053407A (xx) |
EP (1) | EP0206283B1 (xx) |
KR (2) | KR920010048B1 (xx) |
AT (1) | ATE85057T1 (xx) |
BG (1) | BG60527B2 (xx) |
CA (1) | CA1304080C (xx) |
DE (2) | DE3687599T2 (xx) |
DK (1) | DK170473B1 (xx) |
ES (1) | ES8801251A1 (xx) |
FI (1) | FI90241C (xx) |
GR (1) | GR861625B (xx) |
HK (1) | HK91793A (xx) |
IE (1) | IE59463B1 (xx) |
NL (1) | NL980016I2 (xx) |
NO (1) | NO166131C (xx) |
YU (3) | YU44918B (xx) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE110061T1 (de) * | 1986-12-25 | 1994-09-15 | Daiichi Seiyaku Co | Optisch aktive 2,3-dihydrobenzoxazinderivate und verfahren zu deren herstellung. |
NO172846C (no) * | 1987-12-25 | 1993-09-15 | Daiichi Seiyaku Co | Fremgangsmaate for fremstilling av 7,8-dihalogen-3-metyl-2,3-dihydro-2m-benzoksazinderivater og propoksybenzenderivater for utoevelse av fremgangsmaaten. |
US5175160A (en) * | 1988-08-09 | 1992-12-29 | Daiichi Pharmaceutical Co., Ltd. | Antimicrobial agent for animals |
MY104139A (en) * | 1988-08-09 | 1994-02-28 | Daiichi Seiyaku Co | Antimicrobial agent for animals |
AU4376589A (en) * | 1988-11-07 | 1990-05-10 | Gist-Brocades N.V. | Optically active benzoxazines and benzothiazines |
FI94339C (fi) | 1989-07-21 | 1995-08-25 | Warner Lambert Co | Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi |
FR2655545B1 (fr) | 1989-12-11 | 1994-06-10 | Rhone Poulenc Sante | Nouvelle application therapeutique des derives des fluoroquinolones. |
TW208013B (xx) * | 1990-03-01 | 1993-06-21 | Daiichi Co Ltd | |
NO179912C (no) * | 1990-11-28 | 1997-01-08 | Daiichi Seiyaku Co | Analogifremgangsmåte for fremstilling av et terapeutisk virksomt optisk aktivt pyridobenzoksazinderivat |
EP0619311A1 (en) * | 1992-10-07 | 1994-10-12 | Derivados Del Etilo, S.A. | Process for obtaining benzoxazines useful for the synthesis of ofloxacin, levofloxacin and derivatives thereof |
ES2055656B1 (es) * | 1992-10-07 | 1995-11-16 | Etilo Derivados | Procedimiento para la obtencion de benzoxazinas utiles para sintesis de ofloxacina, levofloxacina y derivados. |
US5532239A (en) * | 1993-08-02 | 1996-07-02 | Assistance Publique - Hopitaux De Paris | Therapeutic application of fluoroquinolone derivatives |
ZA946853B (en) * | 1993-09-10 | 1995-04-24 | Daiichi Seiyaku Co | Crystals of antimicrobial compound. |
US5686095A (en) * | 1995-10-23 | 1997-11-11 | Price, Jr.; Francis W. | Method of treating canker sores |
PT934061E (pt) | 1996-07-24 | 2003-10-31 | Warner Lambert Co | Isobutilgaba e seus derivados para o tratamento da dor |
US5997893A (en) * | 1998-01-20 | 1999-12-07 | Ethicon, Inc. | Alcohol based anti-microbial compositions with cosmetic appearance |
US6022551A (en) * | 1998-01-20 | 2000-02-08 | Ethicon, Inc. | Antimicrobial composition |
US5972358A (en) * | 1998-01-20 | 1999-10-26 | Ethicon, Inc. | Low tack lotion, gels and creams |
US6248343B1 (en) | 1998-01-20 | 2001-06-19 | Ethicon, Inc. | Therapeutic antimicrobial compositions |
KR100309871B1 (ko) | 1999-02-24 | 2001-10-29 | 윤종용 | (-)피리도벤즈옥사진 카르복실산 유도체의 제조방법 |
EP1135132A2 (en) | 1998-12-04 | 2001-09-26 | Influx, Inc. | Inhibitors of multidrug transporters |
KR100617952B1 (ko) * | 1999-03-04 | 2006-08-30 | 보령제약 주식회사 | 광학활성 피리도 벤즈옥사진 유도체의 제조방법 |
ES2409383T3 (es) | 1999-09-08 | 2013-06-26 | Daiichi Sankyo Company, Limited | Proceso para producir derivado de benzoxazina y productos intermedios para la producción del mismo |
KR20010103346A (ko) * | 2000-05-09 | 2001-11-23 | 이후근 | 패각 입자와 접착제 그리고 물감을 혼합하여 그림 밑칠용재료를 제조하는 방법 |
JP2004518677A (ja) * | 2000-12-21 | 2004-06-24 | ファルマシア・アンド・アップジョン・カンパニー | 抗菌性キノロン誘導体および細菌感染を治療するためのその使用 |
DE60233307D1 (de) * | 2001-03-07 | 2009-09-24 | Daiichi Sankyo Co Ltd | Verfahren zur herstellung optisch aktiver propoxyanilinderivate |
WO2002088411A1 (en) | 2001-04-27 | 2002-11-07 | Research Institute Of Industrial Science & Technology | High manganese duplex stainless steel having superior hot workabilities and method for manufacturing thereof |
AU2002341991A1 (en) | 2001-10-03 | 2003-04-14 | Teva Pharmaceutical Industries Ltd. | Methods for the purification of levofloxacin |
US7425628B2 (en) | 2001-10-03 | 2008-09-16 | Teva Pharmaceutical Industries Ltd. | Methods for the purification of levofloxacin |
KR100440192B1 (ko) * | 2001-11-22 | 2004-07-12 | 이수화학 주식회사 | 광학 활성 퀴놀론카르복실산 유도체의 제조방법 |
IL162172A0 (en) * | 2001-11-29 | 2005-11-20 | Teva Pharma | Methods for the purification of levofloxacin |
NZ534104A (en) * | 2001-12-24 | 2007-03-30 | Teva Pharma | Dosage form with a core tablet of active ingredient sheathed in a compressed annular body of powder or granular material |
US20040052843A1 (en) * | 2001-12-24 | 2004-03-18 | Lerner E. Itzhak | Controlled release dosage forms |
IL163666A0 (en) | 2002-02-22 | 2005-12-18 | New River Pharmaceuticals Inc | Active agent delivery systems and methods for protecting and administering active agents |
CA2495271A1 (en) * | 2002-08-14 | 2004-08-19 | Teva Pharmaceutical Industries Ltd | Synthesis of gatifloxacin |
US20040152701A1 (en) * | 2002-12-02 | 2004-08-05 | Dr. Reddy's Laboratories Limited | Novel anhydrous crystalline form of Levofloxacin and process for preparation there of |
FR2859471B1 (fr) | 2003-09-09 | 2006-02-03 | Solvay | Procede pour la fabrication d'un compose enantiopur |
CA2596993A1 (en) | 2005-02-07 | 2006-08-10 | Mitsubishi Pharma Corporation | Optically active tetrahydronaphthalene derivative |
US7838532B2 (en) * | 2005-05-18 | 2010-11-23 | Mpex Pharmaceuticals, Inc. | Aerosolized fluoroquinolones and uses thereof |
US8524735B2 (en) | 2005-05-18 | 2013-09-03 | Mpex Pharmaceuticals, Inc. | Aerosolized fluoroquinolones and uses thereof |
WO2007097940A2 (en) * | 2006-02-13 | 2007-08-30 | Trustees Of Boston University | Reca inhibitors with antibiotic activity, compositions and methods of use |
US7973022B2 (en) | 2006-02-17 | 2011-07-05 | Idexx Laboratories, Inc. | Fluoroquinolone carboxylic acid salt compositions |
US20070197548A1 (en) | 2006-02-17 | 2007-08-23 | Murthy Yerramilli V S | Fluoroquinolone compositions |
US20100234348A1 (en) * | 2006-08-04 | 2010-09-16 | Trustees Of Boston University | Compositions and methods for potentiating antibiotic activity |
US20100029938A1 (en) * | 2006-12-22 | 2010-02-04 | Farmaprojects, S. A. | Process for the preparation of an antibacterial quinolone compound |
EP1939206A1 (en) * | 2006-12-22 | 2008-07-02 | Farmaprojects, S.A. | Process for the preparation of an antibacterial quinolone compound |
US7964723B2 (en) | 2008-08-02 | 2011-06-21 | Apeloa-Kangyu | And practical process for exclusively producing (S)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido-[1,2,3,de][1,4]benzoxazine-6-carboxylic acid hemihydrate |
HUE050147T2 (hu) | 2008-10-07 | 2020-11-30 | Horizon Orphan Llc | Tüdõgyulladás csökkentése levofloxacin belélegzése útján |
NO2344129T3 (xx) | 2008-10-07 | 2018-07-21 | ||
NZ596492A (en) | 2009-05-15 | 2013-08-30 | Redx Pharma Ltd | Redox drug derivatives |
RU2563809C2 (ru) | 2009-09-04 | 2015-09-20 | Мпекс Фармасьютикалс, Инк. | Применение левофлоксацина в форме аэрозоля для лечения муковисцидоза |
CN101659669B (zh) * | 2009-09-04 | 2011-07-20 | 诚达药业股份有限公司 | 左旋氧氟沙星的制备方法 |
CN102775424A (zh) * | 2012-07-09 | 2012-11-14 | 浙江司太立制药股份有限公司 | 一种左氧氟沙星杂质的制备方法 |
MX2015011760A (es) | 2013-03-15 | 2016-06-10 | Melinta Therapeutics Inc | Metodos para tratar infecciones en pacientes obesos y con sobrepeso usando antibioticos. |
CA2948595C (en) * | 2014-05-09 | 2021-07-13 | Tecnimede Sociedade Tecnico-Medicinal S.A. | Pharmaceutically acceptable salts of pirlindole enantiomers for use in medicine |
CN105037388A (zh) * | 2015-08-28 | 2015-11-11 | 安徽环球药业股份有限公司 | 一种安妥沙星的制备方法 |
CN105367585B (zh) * | 2015-12-02 | 2017-11-17 | 山东齐都药业有限公司 | 左氧氟沙星杂质的制备方法 |
EP4149427A1 (en) | 2020-06-11 | 2023-03-22 | Sentiss Pharma Private Limited | Ophthalmic compositions comprising a combination of fluoroquinolone antibacterial agent and an anti-inflammatory agent |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5746986A (en) * | 1980-09-02 | 1982-03-17 | Dai Ichi Seiyaku Co Ltd | Pyrido(1,2,3-de)(1,4)benzoxazine derivative |
JPS5852290A (ja) * | 1981-09-21 | 1983-03-28 | Dai Ichi Seiyaku Co Ltd | ピリドベンゾオキサジンカルボン酸誘導体 |
DE3543513A1 (de) * | 1985-12-10 | 1987-06-11 | Bayer Ag | Enantiomerenreine 1,8-verbrueckte 4-chinolon-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende arzneimittel und ihre verwendung zur herstellung von arzneimitteln |
-
1986
- 1986-06-18 DK DK285086A patent/DK170473B1/da active Protection Beyond IP Right Term
- 1986-06-18 NO NO862426A patent/NO166131C/no not_active IP Right Cessation
- 1986-06-19 YU YU1073/86A patent/YU44918B/xx unknown
- 1986-06-19 IE IE163186A patent/IE59463B1/en not_active IP Right Cessation
- 1986-06-19 CA CA000512000A patent/CA1304080C/en not_active Expired - Lifetime
- 1986-06-19 ES ES556292A patent/ES8801251A1/es not_active Expired
- 1986-06-19 FI FI862643A patent/FI90241C/fi not_active IP Right Cessation
- 1986-06-20 KR KR1019860004934A patent/KR920010048B1/ko not_active IP Right Cessation
- 1986-06-20 DE DE8686108442T patent/DE3687599T2/de not_active Expired - Lifetime
- 1986-06-20 DE DE19863687599 patent/DE19875012I2/de active Active
- 1986-06-20 US US06/876,623 patent/US5053407A/en not_active Expired - Lifetime
- 1986-06-20 EP EP86108442A patent/EP0206283B1/en not_active Expired - Lifetime
- 1986-06-20 GR GR861625A patent/GR861625B/el unknown
- 1986-06-20 AT AT86108442T patent/ATE85057T1/de active
-
1988
- 1988-10-05 YU YU1867/88A patent/YU45512B/xx unknown
-
1989
- 1989-03-23 US US07/327,653 patent/US4985557A/en not_active Expired - Lifetime
- 1989-10-30 YU YU2098/89A patent/YU45524B/xx unknown
-
1990
- 1990-10-31 KR KR1019900017517A patent/KR940003757B1/ko not_active IP Right Cessation
-
1991
- 1991-08-28 US US07/754,198 patent/US5142046A/en not_active Expired - Lifetime
-
1993
- 1993-09-02 HK HK917/93A patent/HK91793A/xx not_active IP Right Cessation
-
1994
- 1994-02-22 BG BG098511A patent/BG60527B2/bg unknown
-
1998
- 1998-04-22 NL NL980016C patent/NL980016I2/nl unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PE | Patent expired |
Effective date: 20060619 |