WO2006123427A1 - 眼内レンズ - Google Patents
眼内レンズ Download PDFInfo
- Publication number
- WO2006123427A1 WO2006123427A1 PCT/JP2005/009278 JP2005009278W WO2006123427A1 WO 2006123427 A1 WO2006123427 A1 WO 2006123427A1 JP 2005009278 W JP2005009278 W JP 2005009278W WO 2006123427 A1 WO2006123427 A1 WO 2006123427A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- optical
- outer peripheral
- intraocular lens
- edge
- support
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2002/1681—Intraocular lenses having supporting structure for lens, e.g. haptics
- A61F2002/1683—Intraocular lenses having supporting structure for lens, e.g. haptics having filiform haptics
Definitions
- Intraocular lens Intraocular lens
- the present invention relates to a one-piece intraocular lens in which an optical part and a support part are integrally formed, and more particularly to an intraocular lens that is effective in suppressing secondary cataract.
- cataract which is a kind of eye disease
- a method of removing an eye lens and using an intraocular lens as an alternative to the eye lens is widely known.
- Such an intraocular lens is used by being inserted into a sac excluding the lens, and has an optical part that substitutes for the function of the crystalline lens and a support part that positions and fixes the optical part in the sac.
- a clear edge portion is continuously formed over the entire circumference at the corner edge portion where the rear surface of the optical portion intersects the outer peripheral surface. Therefore, by pressing this edge portion against the posterior capsule, it is possible to easily realize the firm and stable contact of the outer peripheral edge portion of the optical portion with the entire circumference of the posterior capsule.
- the support portion protrudes from the outer peripheral edge portion of the optical portion with substantially the same thickness. For this reason, there is no corner edge at the outer peripheral edge of the optical part at the site where the support part is formed. Therefore, it is extremely difficult to strongly press the optical part against the posterior capsule at the site where the support part is formed, and as a result, epithelial cells easily circulate through the strong part, and the effect of suppressing secondary cataract is reduced. It ends up.
- Patent Document 1 WO2004 / 096099A1
- Patent Document 2 Specific Table 2003-504115
- the thickness dimension of the support part formed by protruding the outer peripheral surface force of the optical part is made smaller than the thickness dimension of the outer peripheral face of the optical part.
- the thickness dimension of the support part must be made smaller than the thickness dimension of the outer peripheral surface of the optical part. Therefore, it is very difficult to obtain sufficient strength of the support part, and it is difficult to ensure sufficient shape stability and position stability under wearing condition due to insufficient strength of the support part.
- the pressing force against the posterior capsule at the corner edge based on the action of the force transmitted through the arm may be insufficient.
- the latter intraocular lens disclosed in Patent Document 2 has a support portion that is formed so as to protrude from the optical portion.
- a step portion is formed on the rear surface at a close position, and the step portion is used to form a corner edge portion at the formation position of the support portion.
- the step portion to be applied is in the width direction of the support portion at both end edges in the width direction of the support portion. Connected to both end faces in a substantially orthogonal state.
- the corner edge portion formed from the outer peripheral edge portion of the optical portion using the rear surface of the support portion has a substantially right-angled break point. When such a fold point exists, when the corner edge portion is pressed against the posterior capsule, a saddle-like irregular deformation is likely to occur in the posterior capsule with the fold point as the center.
- the surface of the posterior capsule may not follow the corner edge formed on the outer peripheral edge of the rear surface of the optical part or the support part, which may cause a gap or the like.
- the posterior capsule has a spherical shape that is not only flexible, but the fold point that is applied is positioned on the outermost side. Thus, there is no denying the possibility of a gap between the posterior capsule and the corner edge on the center side of the pressing point of the break point.
- Patent Literature l WO2004Z096099Al
- Patent Document 2 Special Table 2003-504115
- the present invention has been made in the background as described above, and the problem to be solved is that the outer peripheral portion of the optical unit is placed around the posterior capsule under wearing conditions. It is an object of the present invention to provide an intraocular lens having a novel structure that can be stably pressed for a long period of time and thereby can more advantageously suppress the development of subsequent cataract. Means for solving the problem
- the first aspect of the present invention includes an optical part that includes a lens region having predetermined optical characteristics and is substantially circular in a front view, and extends from the optical part toward the outer peripheral side.
- a support portion that is positioned and held so that the optical portion is pressed against the inner surface of the retinal side of the sac by being brought into contact with the inner surface of the outer peripheral portion of the sac under insertion into the eye,
- a one-piece type that is formed integrally and has an edge-shaped angular edge formed so as to surround the optical part on the rear side in the optical axis direction of the optical part and pressed against the inner surface of the retinal side of the sac
- a pair of connecting portions extending outward in the radial direction from the outer peripheral portion facing the optical portion in one radial direction is formed with a larger circumferential length than the support portion.
- connection portion of the support portion at the outer peripheral edge portion of the connection portion protrudes rearward from the support portion, so that it surrounds the optical portion over the entire circumference.
- the corner edges that extend continuously are formed in cooperation with the outer peripheral edges on the rear surfaces of the optical part and the pair of connecting parts, and the corner edges extend over the entire circumference in the circumferential direction. It is characterized by being formed with a smoothly extending shape.
- the corner edge formed by the cooperation of the optical part and the connecting part continuously surrounds the optical part so as to surround the optical part.
- the corner edge formed by the cooperation of the optical part and the connecting part continuously surrounds the optical part so as to surround the optical part.
- a reduction in the incidence of secondary cataract can be realized.
- the corner edge portion including the folding point in the circumferential direction is pressed against the inner surface of the sac in the state of being implanted in the sac of the intraocular lens.
- the stress concentration is concentrated on the inner surface of the sac where the strong break point is pressed.
- irregular deformation such as wrinkles occurs on the inner surface of the flexible sac, so that the close contact of the corner edge with the inner surface of the sac cannot be sufficiently maintained, and effectively prevents the epithelial cells from entering the optical region. It was difficult.
- the corner edge extending in the circumferential direction is formed smoothly and continuously over the entire circumference in the circumferential direction.
- the intraocular lens structured according to the present embodiment even when worn, the inner surface of the posterior capsule that exhibits a flexible and spherical curved surface is deformed irregularly by the contact of the corner edges. A corner edge is stably pressed over the entire circumference of the inner surface of the sac that does not occur, and a close contact state can be formed advantageously.
- the pair of support portions are connected to the optical portion via the pair of connecting portions, and the thickness dimension of the outer peripheral edge portion of the connecting portion from which the support portion protrudes is set to be outside the optical portion.
- the thickness is made larger than the thickness dimension at the position at the peripheral edge where the connecting portion is removed. Therefore, when the corner edge portion is formed, the thickness of the support portion can be set with a greater degree of freedom than when the support portion is formed so as to directly project the outer peripheral surface force of the optical portion. Accordingly, it is possible to avoid the thinning of the proximal end portion of the support portion, it is possible to sufficiently secure the strength of the support portion, and it is possible to stably position and fix the intraocular lens in the sac. Further, the pressing force against the inner surface of the sac at the corner edge can be obtained more advantageously.
- a second aspect of the present invention is the intraocular lens according to the first aspect, wherein the angular edge force is convex toward the straight line or the outer peripheral side over the entire circumference in the circumferential direction. It is characterized by an outer circumferential convex curve.
- the corner edge portion is more stably adhered to the inner surface of the posterior capsule formed by the spherical curved surface, and the subsequent cataract
- the spherical curved surface is formed by the corner edge being formed in a straight line or a curve that protrudes toward the outer circumferential side over the entire circumference. The corner edge is brought into contact with the inner surface of the sac constituted by a wider area.
- the stress and strain due to the contact of the intraocular lens with the inner surface of the sac can be dispersed in a wider area of the sac, and the contact state of the intraocular lens can be reduced by avoiding concentration of the stress and strain at a specific location. Stable maintenance can be realized advantageously.
- the angular edge portion extends around the entire circumference with respect to the central axis of the optical portion. It is characterized by being positioned on substantially the same plane that extends substantially orthogonally.
- the inner surface of the sac is formed into a spherical curved surface by positioning the corner edge on substantially the same plane over the entire circumference.
- a pressing force is applied substantially evenly over the entire circumference of the corner edge, so that a substantially uniform contact state can be obtained over the entire circumference of the corner edge, and the pressing force is reduced. Irregular deformation of the sac due to concentration at a specific location can be avoided, and the close contact state of the corner edge with the sac inner surface can be advantageously ensured.
- a rear surface of the connecting portion is substantially orthogonal to a central axis of the optical portion.
- the front surface of the connecting portion is an inclined surface that gradually protrudes toward the front surface side as it is separated from the optical portion toward the outer peripheral side.
- the rear surface of the connecting portion is a substantially flat surface extending in a direction substantially perpendicular to the central axis of the optical portion, so that the corner edge portion is entirely formed. It is located on substantially the same plane that extends perpendicular to the central axis of the optical part over the circumference. Therefore, it is possible to obtain a substantially constant and stable contact state over the entire circumference, to prevent irregular deformation of the sac, and to ensure a contact state of the corner edge to the sac. Is possible. Since the front surface of the connecting portion is an inclined surface that gradually protrudes toward the front surface as the distance from the optical portion increases in the radial direction, the connecting portion gradually increases in thickness toward the outer peripheral side. It is possible to set the wall thickness dimension of the support portion protruding from the outer peripheral edge portion of the portion with a large degree of freedom.
- the rear surface of the connecting portion gradually moves toward the rear surface side as it moves away from the optical portion toward the outer peripheral side.
- the front surface of the connecting portion gradually protrudes toward the front surface side as it moves away from the outer peripheral side from the optical portion, and the connecting portion is more than the rear surface of the connecting portion. The inclination angle of the front surface of the part is increased.
- the rear surface of the coupling portion is an inclined surface that gradually protrudes toward the rear surface as it is directed toward the outer peripheral side.
- the corner edge is advantageously brought into close contact with the inner surface of the sac.
- the corner edge can be easily formed into an acute cross-sectional shape. It is also possible.
- the inclination angle of the rear surface of the connecting portion is smaller than the inclination angle of the front surface, the thickness of the support portion can be sufficiently increased without significantly increasing the protruding height of the outer peripheral edge portion of the connecting portion to the rear surface side. Can be secured.
- the corner edge at an acute angle, it is possible to advantageously obtain a close contact state with the posterior capsule, but by preventing the corner edge from protruding greatly toward the rear surface relative to the position of the rear surface of the optical unit, The adhesion to the posterior capsule of the surface can be effectively realized, and the adhesion to the posterior capsule on the rear surface side of the intraocular lens can be effectively realized.
- a sixth aspect of the present invention is the intraocular lens according to any one of the first to fifth aspects, wherein a thickness dimension of a proximal end portion protruding from the connecting portion in the support portion is provided.
- the thickness of the outer peripheral edge of the optical part is not less than the thickness of the position where the connecting part is not formed.
- the intraocular lens having the structure according to this aspect irregular deformation such as buckling due to stress concentration during wearing occurs at the connection portion between the connecting portion and the supporting portion. It can be suppressed more advantageously. Furthermore, the contact reaction force due to the contact of the support portion with the sac is efficiently transmitted to the corner edge portion, and a sufficient pressing force is allowed to act stably so that it becomes flexible.
- a thickness dimension of an outer peripheral edge portion of the optical portion is equal to that of the connecting portion. It is characterized in that it is substantially constant over the entire circumference including the formed part and the part where the connecting part is formed. [0031] In the intraocular lens having the structure according to this aspect, it is possible to prevent the occurrence of problems such as optical distortion of the optical unit. With the presence of the connecting portion, the thickness of the base end portion of the support portion can be set without being restricted by the thickness of the outer peripheral edge portion of the optical portion.
- an eighth aspect of the present invention is the intraocular lens according to any one of the first to seventh aspects, wherein a pair of an outer peripheral edge portion of the optical portion constituting the corner edge portion and a pair of In the outer peripheral edge portion of the connecting portion, an outer peripheral surface rising from the corner edge portion is an axial surface extending substantially parallel to the central axis of the optical portion over the entire periphery. .
- the outer peripheral surface rising from the corner edge is an axial surface extending substantially parallel to the central axis of the optical unit. It becomes possible to advantageously form the edge shape of the corner edge portion formed in cooperation with the outer peripheral edge portion on each rear surface side of the optical portion and the pair of connecting portions.
- At least a part of the corner edge has an acute cross-sectional shape. It is characterized by that.
- the contact force with respect to the sac is concentrated, and more stable contact with the inner surface of the sac of the corner edge can be realized. .
- an outer peripheral edge portion of the connecting portion is concentric with a central axis of the optical portion.
- An arcuate tip peripheral portion having an arcuate outer peripheral surface shape, and both side peripheral portions that smoothly connect both end portions in the circumferential direction of the arcuate tip peripheral portion to the outer peripheral portion of the optical portion;
- the width of the support portion is made smaller than the circumferential length of the arcuate tip peripheral portion, and the circumferential central partial force of the arcuate tip peripheral portion protrudes from the support portion. It is formed.
- the intraocular lens according to the present invention can be more easily manufactured.
- the cutting process (race cutting method)
- the circumferential shape of the outer peripheral edge of the optical part and the connecting part are both concentric arcs.
- Cutting operation control is easy and cutting is possible with high accuracy.
- the molding method internal stress and residual strain due to shrinkage during polymerization can be reduced or avoided.
- the pair of support portions are respectively arranged with respect to a central axis of the optical portion.
- the center point in the thickness direction of the support part is biased toward the front side of the optical part with respect to the center point in the thickness direction of the optical part. It is characterized by being crisp.
- the support portion is formed so as to extend in a direction substantially orthogonal to the central axis of the optical portion without being inclined, A pressing force against the inner surface of the sac can be advantageously obtained. That is, conventionally, the support portion is formed so that the protruding tip side gradually inclines toward the front surface side, and the contact reaction force against the sac transmitted to the optical portion via the support portion by the forceful inclination is divided. The force acted to displace the optical part to the rear side.
- the support portion is optically displaced because the center in the thickness direction of the support portion is biased to the front side rather than the center in the thickness direction of the optical portion!
- the contact reaction force against the posterior capsule transmitted to the optical part via the support part is the center of the thickness of the optical part It is transmitted with a deviation in the axial direction from the point. Therefore, the distortion due to the transmitted contact reaction force, and the component force thereof, can be displaced so as to press the optical part against the inner surface of the sac on the rear side, so that an effective pressing force can be exerted at the corner edge.
- the support portion so as to extend in a direction substantially orthogonal to the central axis of the optical portion, it becomes very easy to manufacture an intraocular lens as compared to the case where the inclined support portion is formed. In the case of manufacturing by cutting, the axial dimension of the lens branch can be set small, the yield of the lens material can be improved, and the manufacturing cost can be reduced.
- the intraocular lens according to any one of the first to eleventh aspects is integrally formed of a soft material that can be folded or raised. It is characterized by that.
- the strength of the support portion is particularly high. Even if the intraocular lens formed of a soft material is easily problematic, the strength of the support portion can be advantageously obtained, and the optical portion can be positioned stably by the support portion and the inner surface of the sac of the corner edge can be fixed to the inner surface of the capsule. Adhesion can be realized. In addition, by forming it with a soft material, it is more optical than the corner edge formed on the outer peripheral edge on the rear surface side of the optical part that is easily deformed according to the shape of the inner surface of the sac that exhibits a spherical curved surface.
- the corner edge force formed on the outer peripheral edge on the rear surface side of the connecting part positioned perpendicular to the axis of the part axis is more stably brought into contact with the inner surface of the sac.
- the adhesion of the part to the sac can be improved.
- the optical unit is arranged around the entire circumference when the intraocular lens is inserted into the eye.
- the angular edge formed so as to surround the entire surface is stably pressed against the posterior capsule over the entire circumference, so that migration of epithelial cells to the optical region can be advantageously avoided. Therefore, it is possible to effectively suppress the subsequent cataract caused by epithelial cells entering the optical region and becoming turbid.
- FIG. 1 is a front view showing a one-piece intraocular lens as a first embodiment of the present invention.
- FIG. 2 is a rear view of the one-piece type intraocular lens shown in FIG.
- FIG. 3 is a side view of the one-piece intraocular lens shown in FIG. 1.
- FIG. 4 is a longitudinal sectional view of the one-piece type intraocular lens shown in FIG. 1, and corresponds to a IV IV section in FIG.
- FIG. 5 is a front view showing a one-piece intraocular lens as a second embodiment of the present invention.
- FIG. 6 is a rear view of the one-piece intraocular lens shown in FIG.
- FIG. 7 is a side view of the one-piece intraocular lens shown in FIG.
- FIG. 8 is a rear view showing a one-piece intraocular lens as a third embodiment of the present invention.
- FIG. 9 is a rear view showing a one-piece intraocular lens as a fourth embodiment of the present invention.
- FIG. 13 is a rear view showing a one-piece type intraocular lens as a seventh embodiment of the present invention.
- FIG. 15 is a rear view showing a one-piece type intraocular lens according to a ninth embodiment of the present invention.
- FIG. 16 is a rear view showing a one-piece intraocular lens as a tenth embodiment of the present invention.
- FIG. 20 is a side view of the one-piece intraocular lens shown in FIG.
- XXI A view corresponding to a cross section of XXI.
- FIGS. 1 to 4 show a foldable intraocular lens 10 as a first embodiment of the present invention.
- the intraocular lens 10 includes an optical part 12, a pair of connecting parts 14, 14, and a pair of support parts 16, 16.
- the intraocular lens 10 having the optical part 12, the coupling parts 14, 14, and the support parts 16, 16 in this way has a visible light transmittance sufficient to give a foldable type intraocular lens.
- it can be made of various materials with excellent softness and a certain degree of elasticity, in spite of that.
- it is made of a soft material having a glass transition temperature of 30 ° C. or lower and a refractive index of 1.51 or higher. With such a soft material, the intraocular lens 10 can be easily folded or rolled up at room temperature to make it more compact, and can be more easily inserted into the sac during implantation.
- JP-A-10-24097 and JP-A-11 56998 etc. are suitably used as a molding material for the intraocular lens 10 according to the present invention.
- a monomer containing one or more (meth) acrylic acid esters as shown in (i) below.
- an optional monomer as shown in (ii) below is appropriately blended.
- an additive as shown in (iii) below can be prepared if necessary.
- Hydroxyl-containing (meth) atarylates such as:
- Aromatic ring-containing (meth) atalylates such as:
- Phenolchetyl (Meth) Atarylate Phenol (Meth) Atarylate, Phenol Chetil (Metal
- Crosslinkable monomers such as:
- the connecting portion 14 is an inclined surface in which the connecting portion front surface 22 which is a surface on one side in the optical axis direction (the optical portion front surface 18 side) is gradually inclined toward the front side in the optical axis direction toward the outer peripheral side.
- the connecting portion rear surface 24, which is the other surface, is a flat surface that extends in the direction perpendicular to the optical axis, and the connecting portion 14 as a whole gradually increases in thickness toward the outer peripheral side. .
- the thickness dimension (thickness) in the optical axis direction at the inner peripheral edge of the connecting portion 14 is substantially the same as the thickness dimension (thickness) in the optical axis direction at the outer peripheral edge of the optical portion 12.
- the term “smoothly joined together” means that the joined portions are joined so as to have a common tangent line without including a fold point or a broken line.
- the outer peripheral wall surface 30 is composed of a cylindrical curved surface whose curvature radius changes with a common tangent as a whole.
- the lower end portion of the outer peripheral wall surface 30 is connected to the outer peripheral edge portions of the optical portion rear surface 20 and the connecting portion rear surface 24.
- an obtuse edge shape corresponding to the convex shape of the rear surface 20 of the optical part is formed at the connection part of the outer peripheral wall surface 30 and the optical part rear surface 20, and at the connection part of the outer peripheral wall surface 30 and the connecting part rear surface 24,
- a substantially right-angled edge shape is formed, and an edge portion 32 having an edge shape is continuously formed over the entire circumference of the connection portion between the outer peripheral wall surface 30 and the rear surfaces 20 and 24.
- the edge portion 32 is formed to have a shape extending smoothly around the entire circumference in the circumferential direction so as to surround the optical portion 12, and in this embodiment, the outer peripheral wall surface 30 extends over the entire circumference. It is composed of a curved surface or a flat surface that is convex toward the outer peripheral side, and the edge portion 32 formed at the lower end of the outer peripheral wall surface 30 is convex toward the outer peripheral side over the entire circumference. It is formed continuously in the circumferential direction so as to extend on the outer circumferential convex curve constituted by the curve or straight line.
- the edge portion 32 in the present embodiment extends in the direction perpendicular to the optical axis over the entire circumference.
- the edge portion 32 is formed to have a smoothly extending shape by connecting a function curve, or a plurality of curves or straight lines (including all modes of appropriate combinations thereof) over the entire circumference. It is formed so as not to include a broken line.
- the arc-shaped outer peripheral surface 26 which is the portion having the smallest curvature radius in the circumferential direction at the edge portion 32 and the circumferential direction side.
- the radius of curvature of the connecting portion with the wall surfaces 28, 28 is 0.3 mm or more, more preferably, the radius of curvature of the connecting portion is 0.5 mm or more, and more preferably, the connecting portion.
- the radius of curvature is 1. Omm or more.
- a pair of support portions 16 and 16 are integrally formed on each arcuate outer peripheral surface 26 of the pair of connection portions 14 and 14.
- the pair of support portions 16 and 16 are formed in an elongated rod shape, and the substantially central partial force in the circumferential direction of the arc-shaped outer peripheral surfaces 26 and 26 is also projected outwardly in the radial direction of the optical portion 12.
- the optical part 12 extends in a curved manner along the circumferential direction.
- the outer peripheral side surfaces of the curved portions of the pair of support portions 16 and 16 are contact surfaces 34 and 34, and when the intraocular lens 10 is inserted into the sac, the inner side of the sac is in the eye. It comes to be able to abut.
- the optical unit 12 in this embodiment is positioned and supported at a predetermined position inside the sac by the pair of support units 16 and 16.
- each of the support portions 16, 16 is made thinner than the thickness dimension of the outer peripheral side end portions of the connecting portions 14, 14, and in this embodiment, the optical portion 12
- the wall thickness is slightly thicker than the outer wall thickness.
- the support portions 16 and 16 are formed so as to extend the end portion force on the connection portion front surface 22 side at the outer peripheral side end surfaces of the connection portions 14 and 14.
- a pair of support part front surfaces 36, 36 that are surfaces on one side of the support parts 16, 16 in the optical axis direction, and a pair of connecting part front faces 22, 22 that extend in a direction perpendicular to the outer peripheral edge of the optical axis.
- the intraocular lens 10 implanted so as to be entirely accommodated inside the sac spreads in the sac so as to restore its initial shape based on its own elasticity. If necessary, adjust the position of the intraocular lens 10 in the sac using an appropriate instrument so that the optical axis of the optical unit 12 is substantially aligned with the central axis of ophthalmic optics. Position 10 relative to the sac.
- the distance between the contact surfaces 34 and 34 of the support portions 16 and 16 of the intraocular lens 10 is set to be larger than the inner diameter dimension of the L force capsule. Therefore, the contact surfaces 34, 34 of the support portions 16, 16 are in close contact with the outer peripheral inner surface of the sac so that the optical unit 12 is positioned and fixed in the eye. It becomes.
- the optical part 12 and the connecting part 14 of the intraocular lens 10 are formed on the outer peripheral edge of each of the rear surfaces 20, 24 while the rear surfaces 20, 24 are brought into contact with the inner surface of the sac.
- the edge portion 32 is pressed against the inner surface of the sac to be brought into close contact with the inner surface of the sac, and the inner surface of the sac is bent along the edge shape at the contact point of the edge portion 32 on the inner surface of the sac by the pressing of the edge portion 32 It is deformed into a shape.
- the edge portion 32 is formed by a smooth curve or straight line over the entire circumference in the circumferential direction, and is continuously formed in the circumferential direction so as to extend on a smooth curve not including a break point.
- the outer peripheral surfaces of the optical unit 12 and the connecting units 14, 14 are formed by a smooth outer peripheral wall surface 30 having no corners.
- the edge portion 32 is formed by the outer peripheral wall surface 30 and the rear surfaces 20 and 24, which are powerful, so that the edge portion 32 extends continuously and smoothly over the entire circumference.
- the thickness dimension in the optical axis direction at the outer peripheral edge portion of the connecting portion 14 T force
- the thickness dimension in the optical axis direction of the inner peripheral edge portion of the connecting portion 14 larger than t.
- the portions where the connecting portions 14 and 14 are formed on the outer peripheral edge of the optical unit 12 are particularly thick.
- the thickness of the outer peripheral edge of the optical unit 12 is substantially constant over the entire circumference.
- the connecting parts 14 and 14 are formed in a shape having a thick outer peripheral side, and the optical part 12 is connected to the optical part 12 via the connecting parts 14 and 14
- the connecting portion front surfaces 22, 22 are formed of inclined surfaces that gradually incline toward the optical axis direction front side toward the optical axis perpendicular direction outward side, and the support portion 16 , 16 are formed so as to extend from the end on the front side of the connecting part 22, 22 on the outer peripheral surface of the connecting parts 14, 14. Therefore, the abutting reaction force acting on the support portions 16 and 16 when the intraocular lens 10 is implanted in the sac causes the optical portion 12 and the connecting portions 14 and 14 to be displaced rearward in the optical axis direction. It is becoming easy to be done.
- the outer peripheral surface of the connecting portion 14 is convex so as to be directed outward in the direction perpendicular to the optical axis. Therefore, the edge portion 32 is more stably brought into contact with the inner surface of the sac having a spherical curved surface over the entire circumference, and the stress and strain due to the contact are distributed over a wide range of the inner surface of the sac. Therefore, a close contact state can be advantageously obtained without forming a gap between the edge portion 32 and the inner surface of the sac.
- the edge portion 32 is formed so as to extend on the connecting portion rear surface 24 which is the same plane extending in a direction substantially perpendicular to the optical axis.
- the edge portion 32 can be brought into close contact with the inner surface of the sac, which has a spherical curved surface, in a substantially uniform contact state over the entire circumference, and the action of concentrated stress is more effective. Can be avoided.
- the pair of support portions 16 and 16 are formed with substantially the same and constant thickness dimensions, and the thickness dimensions of the support portions 16 and 16 are the outer peripheral edges of the optical portion 12. It is thicker than the thickness of the part.
- the optical part 12 and the support parts 16 and 16 are connected via the connection parts 14 and 14 that are wider in the circumferential direction than the support parts 16 and 16. Accordingly, it is advantageous that the contact reaction force transmitted by the support portions 16 and 16 is dispersed or buffered by the connecting portions 14 and 14, and the contact reaction force acts on a specific portion of the optical unit 12 in a concentrated manner. Can be prevented. Therefore, it is possible to avoid the occurrence of distortion in the optical unit 12 due to the action of the contact reaction force, and to effectively prevent the occurrence of disturbance of optical characteristics such as astigmatism accompanying the distortion.
- the arcuate outer peripheral surfaces 26 and 26 of the connecting portions 14 and 14 are formed in a substantially concentric shape that curves along the outer peripheral surface of the optical unit 12.
- force cutting race cutting method
- operation control during cutting becomes easy and high-precision cutting is possible, while when formed by molding method, internal stress and Reduction or avoidance of residual distortion can be achieved.
- FIGS. 5, 6 and 7 show a foldable type intraocular lens 42 as a second embodiment of the present invention.
- the first embodiment and Description of substantially the same members or parts will be omitted by attaching the same reference numerals in the drawings.
- the intraocular lens 42 having the structure according to the present embodiment can also exhibit substantially the same effect as that of the first embodiment.
- the connecting portions 44, 44 such as the intraocular lens 42 in the present embodiment to a substantially elliptical shape when viewed from the front, the inner surface of the sac having a spherical curved surface can be stabilized over the entire circumference. It is possible to achieve a more advantageous distribution of stress and strain exerted on the sac and to improve adhesion.
- FIG. 8 shows an intraocular lens 50 as a third embodiment of the present invention.
- the connecting portion 52 has a substantially rectangular shape when viewed from the front, and a part of the outer peripheral surface of the connecting portion 52 has a substantially concave shape directed toward the outer peripheral side.
- a recessed portion 54 is formed.
- Such an intraocular lens 50 can also exhibit substantially the same effects as the intraocular lenses 10 and 42 in the first and second embodiments.
- the concave portions 54 are formed in the pair of coupling portions 52 and 52, respectively, so that the coupling portions 52 and 52 in the opposing direction of the concave portions 54 and 54 are formed.
- the thickness dimension of 52 becomes smaller. Therefore, even when the connecting parts 52 and 52 are formed thicker than the outer peripheral edge part of the optical part 12, the intraocular lens 50 is easily bent with the opposing direction of the recessed parts 54 and 54 as an axis. Therefore, it is possible to advantageously realize the compactness of the intraocular lens 50 by folding up when inserted into the sac.
- the intraocular lens 50 set in a specific insertion tool is pushed into the eye by pushing with a plunger
- the concave concave portions 54, 54 are formed in the connecting portions 52, 52.
- the tip of the plunger is brought into contact with the recesses 54, 54 of the connecting portions 52, 52 and pushed in, it is easily positioned in the direction perpendicular to the optical axis. Therefore, when pushing the intraocular lens 50 into the eye with the plunger, the force required for positioning in the direction perpendicular to the optical axis can be kept small, and the insertion work can be facilitated.
- the recesses 54 and 54 are formed so as to face each other in the radial direction of the optical part 12, the positioning work such as centering after the insertion of the intraocular lens 50 into the sac is performed with high accuracy. And it can be done easily.
- the edge portion 64 By configuring the edge portion 64 with an acute angle in this manner, the thickness dimension at the outer peripheral edge portion of the connecting portion 66 in the present embodiment can be secured more advantageously, and the intraocular lens 60 can be implanted in the sac. In the state, the adhesion to the inner surface of the sac at the edge portion 64 can be more firmly realized, and the invasion of epithelial cells into the optical region can be advantageously prevented.
- the inclination angle of the connecting portion rear surface 62 by setting the inclination angle of the connecting portion rear surface 62 to be smaller than the inclination angle of the connecting portion front surface 22, the formation position of the edge portion 64 in the optical axis direction is compared with the optical portion rear surface 18.
- FIG. 12 shows an intraocular lens 68 as a sixth embodiment of the present invention.
- the support portion 70 is bifurcated at a middle portion thereof, and the protruding tip side portion from the middle portion is along the circumferential direction of the optical portion 12. And are extended in opposite directions.
- the optical portion 12 can be fixedly supported more stably in the inserted state into the sac.
- FIG. 13 shows an intraocular lens 72 as a seventh embodiment of the present invention.
- FIG. 14 shows an intraocular lens 80 as an eighth embodiment of the present invention.
- the support portion 82 is formed in a rod shape extending substantially linearly, and is bent in a direction perpendicular to the optical axis while being partly in the middle of the support portion 82! /
- the base end portion 84 that is closer to the connecting portion 14 than the middle portion is wider than the protruding tip portion 86.
- the intraocular lens 80 having such a support portion 82 it is possible to achieve substantially the same effect as in the seventh embodiment, and the protruding tip of the support portion 82 is more than the inner surface of the sac. It can be engaged strongly.
- FIGS. 16 and 17 show an intraocular lens 96 as a tenth embodiment of the present invention.
- the support portion 98 is formed into an elongated rod shape extending in an arc shape with a substantially constant width as a whole, and the protrusion is projected so as to protrude from the rear surface 38 of the support portion at the protruding tip portion. 100 is formed.
- the protrusion 100 formed on the rear surface 38 of the support portion causes the other end portion of the support portion 98 to be overlapped in the folded state when the intraocular lens 96 is inserted into the sac. Adhesion can be advantageously prevented, and the support portion 98 is stably restored to the initial shape after insertion, so that the optical portion 12 can be reliably positioned and fixed at the initial position.
- the optical unit 12 is circular in front view as shown in the first and second embodiments.
- the optical unit does not necessarily have a circular shape when viewed from the front.
- the width dimension of the support portion may change between the proximal end side and the distal end side, and the support portion
- the thickness dimension which is the dimension in the optical axis direction, may also be set appropriately according to characteristics such as strength required for the support portion. Specifically, for example, by adopting such a support portion that the support portion may gradually become thinner toward the protruding tip side, the strength of the protruding tip portion is lowered and contacted. The reaction force at the time can be suppressed, and the strength of the proximal end portion can be sufficiently secured to sufficiently exert the positioning action of the intraocular lens by the support portion.
- the outer peripheral wall surfaces 30 and 46 are formed so as to extend in a direction substantially parallel to the optical axis direction, and accordingly, the outer peripheral wall surfaces 30 and 46 are configured.
- the outer peripheral surface of the optical part 12 and the outer peripheral surface force of the connecting parts 14, 44, 52, 58 are all forces composed of curved surfaces spreading parallel to the optical axis direction.
- the outer peripheral surfaces of the connecting portions 14, 4, 44, 52, and 58 are not necessarily formed so as to extend substantially in the optical axis direction.
- the curved surface of the outer wall is an inclined surface in which the front side in the optical axis direction gradually inclines outward in the perpendicular direction of the optical axis, thereby connecting the support portion to the connecting portion.
- the edge angle formed by the cross section of the edge portion can be easily made sharp by making the outer peripheral wall surface an inclined surface in which the front side gradually inclines in the direction perpendicular to the optical axis in the optical axis direction.
- the adhesion to the inner surface of the sac can be improved.
- the connecting portions are provided with rounded widened portions on both sides in the width direction of the proximal end portions of the support portions 16, 70, 74, 82, 90, 98, 108. It is desirable that the width is gradually expanded toward the connecting part with 14, 44, 52, 58, 66. It is like this It is not always necessary to provide a widened portion in the shape of the proximal end of the support portions 16, 70, 74, 82, 90, 98, 108.
Landscapes
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Abstract
Description
Claims
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007516181A JP4689668B2 (ja) | 2005-05-20 | 2005-05-20 | 眼内レンズ |
EP05741635.6A EP1882461B1 (en) | 2005-05-20 | 2005-05-20 | Intraocular lens |
CN2005800498497A CN101180009B (zh) | 2005-05-20 | 2005-05-20 | 人工晶体 |
US11/912,499 US8267996B2 (en) | 2005-05-20 | 2005-05-20 | Intraocular lens |
ES05741635.6T ES2551677T3 (es) | 2005-05-20 | 2005-05-20 | Lente intraocular |
PCT/JP2005/009278 WO2006123427A1 (ja) | 2005-05-20 | 2005-05-20 | 眼内レンズ |
KR1020077025302A KR101153264B1 (ko) | 2005-05-20 | 2005-05-20 | 안내렌즈 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/JP2005/009278 WO2006123427A1 (ja) | 2005-05-20 | 2005-05-20 | 眼内レンズ |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2006123427A1 true WO2006123427A1 (ja) | 2006-11-23 |
Family
ID=37431011
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2005/009278 WO2006123427A1 (ja) | 2005-05-20 | 2005-05-20 | 眼内レンズ |
Country Status (7)
Country | Link |
---|---|
US (1) | US8267996B2 (ja) |
EP (1) | EP1882461B1 (ja) |
JP (1) | JP4689668B2 (ja) |
KR (1) | KR101153264B1 (ja) |
CN (1) | CN101180009B (ja) |
ES (1) | ES2551677T3 (ja) |
WO (1) | WO2006123427A1 (ja) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008220863A (ja) * | 2007-03-15 | 2008-09-25 | Hoya Corp | 軟性眼内レンズ |
WO2009153873A1 (ja) * | 2008-06-19 | 2009-12-23 | Hoya株式会社 | 軟性眼内レンズ |
JP2010158305A (ja) * | 2009-01-06 | 2010-07-22 | Nidek Co Ltd | 眼内レンズ |
JP2011500189A (ja) * | 2007-10-16 | 2011-01-06 | アイオーエル テクノロジー プロダクション | 水晶体嚢用の眼内レンズ |
JP2012511404A (ja) * | 2008-12-11 | 2012-05-24 | ボシュ・アンド・ロム・インコーポレイテッド | 眼内レンズおよび眼内レンズを作製する方法 |
WO2018105640A1 (ja) | 2016-12-07 | 2018-06-14 | 興和株式会社 | トーリック眼用レンズ |
JP2019055152A (ja) * | 2017-09-22 | 2019-04-11 | 株式会社メニコン | 眼内レンズ |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090082861A1 (en) * | 2005-05-20 | 2009-03-26 | Kowa Company, Ltd. | Intraocular lens |
CN102883681A (zh) * | 2010-03-04 | 2013-01-16 | 安伦科技股份有限公司 | 用于形成和修改透镜的系统及由此形成的透镜 |
US9220590B2 (en) | 2010-06-10 | 2015-12-29 | Z Lens, Llc | Accommodative intraocular lens and method of improving accommodation |
KR101242658B1 (ko) * | 2010-10-11 | 2013-03-19 | 한국과학기술연구원 | 고굴절 친수성 안내 렌즈 및 그 제조방법 |
US8940045B2 (en) * | 2010-11-24 | 2015-01-27 | Santen Pharmaceutical Co., Ltd. | Intraocular lens |
USD688800S1 (en) * | 2011-09-06 | 2013-08-27 | Santen Pharmaceutical Co., Ltd. | Intraocular lens |
US9364318B2 (en) | 2012-05-10 | 2016-06-14 | Z Lens, Llc | Accommodative-disaccommodative intraocular lens |
JP5936461B2 (ja) * | 2012-06-26 | 2016-06-22 | Hoya株式会社 | 眼内レンズ |
ES2457840B1 (es) * | 2012-09-28 | 2015-02-16 | Universidad De Murcia | Lente intraocular acomodativa de potencia variable y conjunto de lente intraocular acomodativa de potencia variable y anillo capsular |
CN106956082A (zh) * | 2016-01-11 | 2017-07-18 | 广东东阳光药业有限公司 | 人工晶体制备方法 |
JP2019513533A (ja) | 2016-04-22 | 2019-05-30 | ヴェンチュラ ホールディングス リミテッドVentura Holdings Ltd. | 眼内レンズのためのサスペンションシステム内の折り畳み可能なキャビティ |
WO2018039353A1 (en) | 2016-08-24 | 2018-03-01 | Z Lens, Llc | Dual mode accommodative-disacommodative intraocular lens |
CN106667623A (zh) * | 2016-11-16 | 2017-05-17 | 无锡蕾明视康科技有限公司 | 一种可变多焦点人工晶状体 |
CN108670500A (zh) * | 2018-06-06 | 2018-10-19 | 姚涛 | 一种前囊口辅助固定型人工晶体 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4244060A (en) * | 1978-12-01 | 1981-01-13 | Hoffer Kenneth J | Intraocular lens |
US4661109A (en) * | 1985-08-16 | 1987-04-28 | White Thomas C | Intraocular lens |
JP2003504115A (ja) * | 1999-07-08 | 2003-02-04 | コルネアル アンドゥストリ | 眼内インプラント |
WO2003055416A1 (en) * | 2001-12-21 | 2003-07-10 | Bausch & Lomb Incorporated | Intraocular lens |
WO2004096099A1 (ja) * | 2003-04-28 | 2004-11-11 | Hoya Healthcare Corporation | 一体型眼内レンズ及びその製造方法 |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4343050A (en) | 1980-07-14 | 1982-08-10 | Kelman Charles D | Intraocular lenses |
US4588405A (en) | 1983-06-10 | 1986-05-13 | American Hospital Supply Corporation | Intraocular lens assembly |
GB2171912A (en) | 1985-03-05 | 1986-09-10 | Charles William Simcoe | Hinged intraocular lens |
US4961746A (en) | 1985-08-23 | 1990-10-09 | American Cyanamid Company | Intraocular lens with colored legs and method of making |
US4718905A (en) | 1986-08-13 | 1988-01-12 | Freeman Jerre M | Haptic element using ion beam implantation for an intraocular lens |
US4808181A (en) | 1987-08-07 | 1989-02-28 | Kelman Charles D | Intraocular lens having roughened surface area |
FR2631228B1 (fr) | 1988-05-11 | 1990-08-10 | Domilens Laboratoires | Implant intra-oculaire de chambre anterieure |
JPH02156943A (ja) | 1988-10-07 | 1990-06-15 | Ioptex Res Inc | 眼内レンズ挿入器具 |
US5074942A (en) | 1990-05-15 | 1991-12-24 | Texceed Corporation | Method for making intraocular lens with integral colored haptics |
US5476513A (en) * | 1992-02-28 | 1995-12-19 | Allergan, Inc. | Intraocular lens |
US6322589B1 (en) | 1995-10-06 | 2001-11-27 | J. Stuart Cumming | Intraocular lenses with fixated haptics |
US5425734A (en) | 1993-07-02 | 1995-06-20 | Iovision, Inc. | Intraocular lens injector |
US5716403A (en) | 1995-12-06 | 1998-02-10 | Alcon Laboratories, Inc. | Single piece foldable intraocular lens |
FR2744908B1 (fr) * | 1996-02-20 | 1998-06-12 | W K Et Associes | Implant intraoculaire myopique |
JP3529222B2 (ja) | 1996-07-11 | 2004-05-24 | 株式会社メニコン | 軟質眼用レンズおよびその製法 |
US6488707B1 (en) | 1997-08-20 | 2002-12-03 | Thinoptx, Inc. | Method of implanting a deformable intraocular corrective lens |
JP3641110B2 (ja) | 1997-08-20 | 2005-04-20 | 株式会社メニコン | 軟質眼内レンズ用材料 |
JP3805496B2 (ja) | 1997-08-29 | 2006-08-02 | 株式会社ニデック | 眼内レンズ |
US6129759A (en) | 1997-12-10 | 2000-10-10 | Staar Surgical Company, Inc. | Frosted haptic intraocular lens |
FR2782912B1 (fr) | 1998-09-07 | 2001-01-12 | Georges Baikoff | Implant intra-oculaire de chambre anterieure |
US6152959A (en) | 1999-05-14 | 2000-11-28 | Portney; Valdemar | Iris fixated intraocular lens |
US6193750B1 (en) | 1999-10-15 | 2001-02-27 | Medevec Licensing, B.V. | Collars for lens loops |
DE50013494D1 (de) * | 1999-12-14 | 2006-11-02 | Boehm Hans Georg | Fokussierfähige Intraokularlinse |
FR2804860B1 (fr) | 2000-02-16 | 2002-04-12 | Humanoptics Ag | Implant cristallinien accomodatif |
JP3494946B2 (ja) | 2000-03-09 | 2004-02-09 | 株式会社メニコン | 粘着性が低減された軟質眼内レンズ及びその製法 |
JP4038319B2 (ja) | 2000-03-27 | 2008-01-23 | 株式会社ニデック | 眼内レンズの粘着性を減少させる方法 |
JP2003190193A (ja) | 2001-12-26 | 2003-07-08 | Canon Star Kk | 眼内レンズ |
US20030208267A1 (en) | 2002-05-04 | 2003-11-06 | Kurt Buzard | Anterior chamber phakic lens and methods of implantation |
GB0217606D0 (en) * | 2002-07-30 | 2002-09-11 | Rayner Intraocular Lenses Ltd | Intraocular lens |
US20050187621A1 (en) * | 2004-02-24 | 2005-08-25 | Brady Daniel G. | Foldable unitary intraocular lens |
US20090082861A1 (en) | 2005-05-20 | 2009-03-26 | Kowa Company, Ltd. | Intraocular lens |
-
2005
- 2005-05-20 WO PCT/JP2005/009278 patent/WO2006123427A1/ja not_active Application Discontinuation
- 2005-05-20 JP JP2007516181A patent/JP4689668B2/ja active Active
- 2005-05-20 US US11/912,499 patent/US8267996B2/en active Active
- 2005-05-20 CN CN2005800498497A patent/CN101180009B/zh not_active Expired - Fee Related
- 2005-05-20 KR KR1020077025302A patent/KR101153264B1/ko active IP Right Grant
- 2005-05-20 EP EP05741635.6A patent/EP1882461B1/en not_active Not-in-force
- 2005-05-20 ES ES05741635.6T patent/ES2551677T3/es active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4244060A (en) * | 1978-12-01 | 1981-01-13 | Hoffer Kenneth J | Intraocular lens |
US4661109A (en) * | 1985-08-16 | 1987-04-28 | White Thomas C | Intraocular lens |
JP2003504115A (ja) * | 1999-07-08 | 2003-02-04 | コルネアル アンドゥストリ | 眼内インプラント |
WO2003055416A1 (en) * | 2001-12-21 | 2003-07-10 | Bausch & Lomb Incorporated | Intraocular lens |
WO2004096099A1 (ja) * | 2003-04-28 | 2004-11-11 | Hoya Healthcare Corporation | 一体型眼内レンズ及びその製造方法 |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008220863A (ja) * | 2007-03-15 | 2008-09-25 | Hoya Corp | 軟性眼内レンズ |
JP2011500189A (ja) * | 2007-10-16 | 2011-01-06 | アイオーエル テクノロジー プロダクション | 水晶体嚢用の眼内レンズ |
WO2009153873A1 (ja) * | 2008-06-19 | 2009-12-23 | Hoya株式会社 | 軟性眼内レンズ |
US8623084B2 (en) | 2008-06-19 | 2014-01-07 | Hoya Corporation | Soft intraocular lens |
JP2012511404A (ja) * | 2008-12-11 | 2012-05-24 | ボシュ・アンド・ロム・インコーポレイテッド | 眼内レンズおよび眼内レンズを作製する方法 |
JP2010158305A (ja) * | 2009-01-06 | 2010-07-22 | Nidek Co Ltd | 眼内レンズ |
WO2018105640A1 (ja) | 2016-12-07 | 2018-06-14 | 興和株式会社 | トーリック眼用レンズ |
KR20190091282A (ko) | 2016-12-07 | 2019-08-05 | 코와 가부시키가이샤 | 토릭 안용 렌즈 |
US11366336B2 (en) | 2016-12-07 | 2022-06-21 | Kowa Company, Ltd. | Toric ophthalmic lens |
JP2019055152A (ja) * | 2017-09-22 | 2019-04-11 | 株式会社メニコン | 眼内レンズ |
Also Published As
Publication number | Publication date |
---|---|
US20090030514A1 (en) | 2009-01-29 |
JP4689668B2 (ja) | 2011-05-25 |
ES2551677T3 (es) | 2015-11-23 |
US8267996B2 (en) | 2012-09-18 |
EP1882461A1 (en) | 2008-01-30 |
CN101180009B (zh) | 2010-08-18 |
EP1882461A4 (en) | 2009-12-30 |
JPWO2006123427A1 (ja) | 2008-12-25 |
EP1882461B1 (en) | 2015-08-12 |
KR20080009094A (ko) | 2008-01-24 |
CN101180009A (zh) | 2008-05-14 |
KR101153264B1 (ko) | 2012-06-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2006123427A1 (ja) | 眼内レンズ | |
JP5026261B2 (ja) | 眼内レンズ | |
JP4596492B2 (ja) | 水力調節眼内レンズ | |
JP5436780B2 (ja) | 薄い眼内レンズ | |
JP5858346B2 (ja) | 眼内レンズ | |
JP2009518148A (ja) | 調節アーチレンズ | |
JP2014502863A5 (ja) | ||
JP2023160931A (ja) | 改善された支持部力分布を有する眼内レンズプラットフォーム | |
US20030018386A1 (en) | Anterior chamber angle-supported intraocular lenses with flexible optic and rigid fixation members | |
CN116407339A (zh) | 人工晶状体 | |
JP6257070B2 (ja) | 眼内レンズ | |
JP6934789B2 (ja) | 眼内レンズ | |
US11103343B2 (en) | Intraocular lenses having open-loop haptic structures | |
JP2006006484A (ja) | 眼内レンズ | |
CN207492838U (zh) | 后房型有晶体眼人工晶状体 | |
JP7389743B2 (ja) | 閉ループ支持部構造体を有する眼内レンズ | |
JP2004523301A (ja) | 柔軟な眼内インプラント | |
WO2014003039A1 (ja) | 眼内レンズ |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2007516181 Country of ref document: JP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 11912499 Country of ref document: US |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2005741635 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1020077025302 Country of ref document: KR |
|
WWE | Wipo information: entry into national phase |
Ref document number: 200580049849.7 Country of ref document: CN |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: DE |
|
NENP | Non-entry into the national phase |
Ref country code: RU |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: RU |
|
WWP | Wipo information: published in national office |
Ref document number: 2005741635 Country of ref document: EP |