Classifications

• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
  • A23G1/00—Cocoa; Cocoa products, e.g. chocolate; Substitutes therefor
  • A23G1/30—Cocoa products, e.g. chocolate; Substitutes therefor
  • A23G1/32—Cocoa products, e.g. chocolate; Substitutes therefor characterised by the composition containing organic or inorganic compounds
  • A23G1/40—Cocoa products, e.g. chocolate; Substitutes therefor characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
  • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
  • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
  • A23G3/346—Finished or semi-finished products in the form of powders, paste or liquids
• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
  • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
  • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
  • A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
  • A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
  • A23G3/368—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing vitamins, antibiotics
• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
  • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
  • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
  • A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
  • A23G3/42—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
  • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
  • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
  • A23G3/50—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by shape, structure or physical form, e.g. products with supported structure
  • A23G3/54—Composite products, e.g. layered, coated, filled
• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
  • A23G4/00—Chewing gum
  • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
  • A23G4/10—Chewing gum characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
  • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
  • A23L2/52—Adding ingredients
  • A23L2/60—Sweeteners
• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
  • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
  • A23L27/30—Artificial sweetening agents
  • A23L27/33—Artificial sweetening agents containing sugars or derivatives
• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
  • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
  • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
  • A61P25/00—Drugs for disorders of the nervous system
• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
  • A23G2200/00—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents
  • A23G2200/04—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents containing vitamins, antibiotics, other medicaments
• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
  • A23G2200/00—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents
  • A23G2200/06—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF containing organic compounds, e.g. synthetic flavouring agents containing beet sugar or cane sugar if specifically mentioned or containing other carbohydrates, e.g. starches, gums, alcohol sugar, polysaccharides, dextrin or containing high or low amount of carbohydrate
• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
  • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
• • A—HUMAN NECESSITIES
  • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
  • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
  • A23V2200/00—Function of food ingredients
  • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
  • A23V2200/322—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the nervous system or on mental function

Definitions

• the present invention relates to an agent for maintaining concentration and attention, and a food or drink containing the agent. More specifically, the present invention relates to an agent that enhances concentration and attention and maintains concentration and attention for a longer time and more constantly, and a food and drink containing the agent.
• Background technology
• concentration refers to a mental state that is moderately relaxed and moderately nervous.
• concentration there are two main types of concentration: instantaneous concentration and sustained concentration.
• momentary concentration is defined as the ability that is created by maximizing one's ability with the power exerted instantaneously. For example, sudden danger avoidance ability, imagination ability, and judgment in sports.
• Sustained concentration refers to the ability to work long hours on a monotonous task, work on one thing in a long unit, and complete it all the way to the end. Ability to reproduce short-term memory, attention during driving a car, etc. Lasting.
• Known methods include stress elimination concentration method, one point attention concentration method, environmental maintenance concentration method, and zazen breathing method.
• the following methods are known as methods for improving concentration by taking food.
• sucrose ingestion can improve concentration.
• the mechanism is not clear, but it is alleged that one of the mechanisms is due to elevated blood sugar levels.
• concentration and attention especially when studying for an examination or working.
• the present inventors have found that ingestion of palatinose improves concentration and It has been found that attention can be increased and that it can be sustained for longer and more consistently.
• the present invention provides an agent for maintaining concentration and attention comprising palatinose.
• the present invention also provides a food or drink comprising the agent.
• Figure 1 is a graph showing the results of a creperin test in a control test (a mixture of aspartame and acesulfame calcium).
• FIG. 2 is a graph showing the results of the creperin test in Example 1 (test group, comparative group).
• FIG. 3 is a graph showing the results of a series memory test in Example 2 (test group, comparative group). BEST MODE FOR CARRYING OUT THE INVENTION
• Paranoise pa I at i nose
• isomaltulose isoma l tu lose
• pa I at i nose is also known as isomaltulose (isoma l tu lose), if it is guessed by the guzorecose force ⁇ ⁇ 1 in the fraction.
• 6 A disaccharide composed of glucosyl bonds.
• Palatinose is found naturally in honey and cane juice. It is also present in translocation products produced when mono-glucosyltransferase from bacteria and yeasts acts on sucrose.
• palatinose is produced in short-lived plants by bacteria such as Protaminon rubrum and Serratia pi ymuthi ca. By the action of siltran sulfate, most of sucrose is converted to palatinose.
• the term “concentration and attention” used in the present invention means that when performing tasks that require thinking such as ideas, judgments, calculations, and storage, the thinking related to those tasks is mainly performed and the efficiency of the work is reduced. It means the mental ability to raise.
• tasks that require thinking include, for example, simple computational tasks, short-term memory regeneration, driving a car, learning while taking an exam, associative games, crossword puzzles, or puzzles. Head games such as word games, Go or shogi (Japanese chess), and sports that require strategies such as ball transport or time allocation.
• the “agent that maintains concentration and attention” in the present invention includes, for example, crystalline palatinose and palatinose syrup.
• Crystallized palatinose (trade name: Crystallized Palatinose-1 IC, manufactured by Shin Mitsui Sugar Co., Ltd.) contains more than 99.0% of palatinose (water containing crystallization).
• the palatinose syrup available on the market (trade name: Palatino Syrup ISN or ITN, manufactured by Shin Mitsui Sugar Co., Ltd.) contains 11 to 17% of palatinose, It contains Torre Harulose in addition to stainless steel.
• Trehalulose syrup (trade name: Mildia 75 or 85, manufactured by Shin-Mitsui Sugar Co., Ltd.), which is available on the market, contains 8 to 13% of palatinose.
• one Sushirop may be used as the agent of the present invention.
• agents that maintain concentration and attention include, for example, fondant containing crystalline palatinose or palatinose syrup, granules, tablets, powder mixtures (acidulants, sweeteners, sugar esters, etc.). , Fragrances, etc.) and syrup.
• palatinose is consumed preferably in an amount of 5 g to 50 g at a time, more preferably in an amount of 5 g to 20 g.
• Foods and drinks containing the agent for maintaining concentration and attention of the present invention include various drinks such as soft drinks, near water, sports drinks, jelly drinks, tea drinks, cocoa drinks, and coffee drinks. , Soft candies, hard candies, soft candies, chocolate, chewing gum and other various foods. Further, the agent of the present invention for maintaining the concentration and attention may be added to coffee, tea, cocoa and the like as a sweetener and ingested.
• the concentration and attention are improved, and the concentration and attention are improved. It can be maintained for a longer time and more consistently.
• the Klepelin test was a psychological test in which a subject performed a single-digit addition of two numbers for 30 minutes to clarify the work and behavioral characteristics of the subject. is there.
• the Klepelin test has been used as a method of concentration and attention.
• the subject adds up the numbers in order from the left end to the right end for 1 minute (the first time), and then adds the numbers from the left end in the second row in the same manner. Perform the calculation (second time). Repeat this process for 15 minutes (15 lines).
• the subject Immediately before drinking the test sample, the subject performs the Klepelin test described above and obtains the average value (initial value) of 15 rows.
• the subject ingests the test sample, and after a certain period of time, the subject again performs the cleanup test to obtain an average value.
• the average minus the initial value after a period of time reflects the effect of the test sample on the ability to maintain concentration and attention.
• the intake weights of palatinose and sucrose are set to be equal, and high-potency sweeteners such as aspartame and acesulfame-potassium are added to palatinose to give the same sweetness as sucrose.
• high-potency sweeteners such as aspartame and acesulfame-potassium are added to palatinose to give the same sweetness as sucrose.
• palatinose test group
• the increase in the amount of work achieved is about 6.7 and about 5.6, respectively. This indicates that palatinose ingestion maintains constant concentration and attention.
• sucrose comparative group
• the increase in the amount of work achieved after 90 minutes was about 6.1.
• the increase in the amount of work achieved is about 3.4, which is about half compared to the value after 90 minutes.
• palatinose test group was found to have a significant difference of 1% or less between the mean value and the initial value after 90 minutes.
• a continuous memory test is used to maintain concentration and attention.
• the gender is determined as follows. First, a series memory test is performed on the subject immediately before drinking the test sample to determine the initial value. Subsequently, a test sample is ingested, and a series memory test is performed after a certain period of time. The sequence memory test presents a word card with a five-digit number to the subject for two seconds. Present a total of five sheets. The subject then completes the five-digit numbers shown on the answer sheet in order.
• the degree of sweetness be the same between the materials having sweetness. Therefore, as in the case of the creperin test, the intake weights of palatinose and sucrose are set to be equal, and palatinose has high sweetness aspartame and acesulfame potency. And adjust the sweetness to the sweetness of sucrose.
• palatinose test group
• the increase in the work reached by the serial memory test was about 3.0 and about 4.1, respectively.
• the increase in sucrose comparativative group
• the increase in the amount of palatinose achieved at work is slightly lower than that of sucrose at 90 minutes, but more than twice that of sucrose at 150 minutes.
• palatinose significantly increases the increase in work volume over a longer period of time compared to sucrose.
• sucrose intake can increase concentration and attention in the short term, but concentration And that attention cannot be maintained for a long time and more consistently.
• palatinose can maintain concentration and attention for a longer period of time and more consistently than sucrose.
• Figure 1 shows the results. Mixtures of aspartame and lithium acesulfame hardly increase the work volume achieved by Klepelin inspection. In the examination after 150 minutes, although the increase in the amount of work achieved was slightly observed, it is considered that this was due to the subjects becoming accustomed to the Kreppelin examination.
• Example 1 shows the results. Mixtures of aspartame and lithium acesulfame hardly increase the work volume achieved by Klepelin inspection. In the examination after 150 minutes, although the increase in the amount of work achieved was slightly observed, it is considered that this was due to the subjects becoming accustomed to the Kreppelin examination.
• Example 1 shows the results. Mixtures of aspartame and lithium acesulfame hardly increase the work volume achieved by Klepelin inspection. In the examination after 150 minutes, although the increase in the amount of work achieved was slightly observed, it is considered that this was due to the subjects becoming accustomed to the Kreppelin examination.
• Example 1 shows the results. Mixtures of aspartame and lithium acesulf
• Crystalline palatinose (trade name: Crystalline Palatinose-Ic, manufactured by Shin-Mitsui Sugar Co., Ltd.) 40 g, aspartame 0.06 g, acesulfamcarium 0.06 g, distilled 200 m
• a beverage containing the agent of the present invention was produced by dissolving it in water (amount for one person) (hereinafter referred to as “the beverage produced in Example 1”).
• This addition of aspartame and acesulfame potassium can increase the sweetness of beverages made by dissolving 40 g of palatinose in 20 OmL of distilled water, while distilling 40 g of sucrose into 20 OmL of distilled water. When dissolved in water, the amount is as sweet as the drink.
• Test procedure Separately from the preliminary study, two healthy men and women, aged 25 to 59 years old, were selected as subjects.Two groups of seven subjects (test group, comparison group) Group).
• Figure 2 shows the results. At 90 minutes after ingestion of the beverage, the test group showed an increase in the work achievement of about 6.7, and the comparison group showed an increase in the work achievement of about 6.1.
• test group showed an increase in work arrival of about 5.6, while the comparative group saw an increase in work arrival of about 3.4. Was done. This shows that at 150 minutes after ingestion of the beverage, the test group showed clearly better results than the comparative group.
• the increase in the amount of work achieved after 90 minutes was about 6.7, and the increase in the amount of work achieved after 150 minutes was about 5.6. The decline is small.
• 90 The increase in the amount of work after 1 minute was about 6.1, and the increase in the amount of work after 150 minutes was about 3.4, so that the amount of work clearly decreased with time. .
• Preliminary examination is a group of healthy males and females aged 25 to 59 years old (1). Two groups of 7 subjects (test group, comparison group) Group).
• a series memory test (five sets of five 5-digit numeric cards) was performed without taking anything, and the number of correct points was used as the initial value. Thereafter, 200 mL of the beverage of Example 1 was added to the test group, and 200 mL of the beverage prepared by dissolving 40 g of sucrose in 200 mL of distilled water was added to the comparative group for 5 minutes. Ingested within I let you.
• Figure 3 shows the results.
• the increase in the amount of work achieved was about 3.0 at 90 minutes after ingestion of the beverage and about 1.9 at 150 minutes.
• a significant difference test was performed on the initial value and the increased amount of work reached after 90 minutes, and the initial value and the increased amount of work reached after 150 minutes by the t-test of two matched groups. .
• the increase in the amount of work achieved was about 3.3 at 90 minutes after drinking the beverage and about 1.9 at 150 minutes after drinking the beverage.
• a significant difference test was performed on the initial value and the increased amount of work reached after 90 minutes, and the initial value and the increased amount of work reached after 150 minutes by the t-test of the corresponding two groups.
• the agent (fondane) of the present invention was produced with the following composition.
• Crystal para Tinose (trade name: Crystallized Palatinose-IC, manufactured by Shin Mitsui Sugar Co., Ltd.) was charged at a rate of 120 kg / hour from the raw material inlet of the twin-screw extruder at 160-200 ° C. Melted. Subsequently, water was injected for 5.6 kg hours, cooled, and microcrystallized. Finally, Palatinose Syrup (trade name: Palatinose Syrup ISN, manufactured by Shin Mitsui Sugar Co., Ltd.) was injected at 100 kg / hour, and mixed while cooling.
• the agent (granules) of the present invention was produced using crystalline palatinose (powder).
• Crystal palatinose (trade name: Crystal palatinose IC, 28-68 mesh powder is 70% or more, manufactured by Shin Mitsui Sugar Co., Ltd.) is supplied to a twin-screw extruder at a speed of 40 kg / h. It was introduced from the material inlet and dissolved at 160-180 ° C. Subsequently, water was added at a speed of 2 kg and cooled and precipitated to obtain a powder. The powder was sieved to obtain condyles (10 to 40 mesh, 99% or more).
• Example 5 Example 5
• the agent (tablet) of the present invention was produced with the following composition.
• a tablet having a diameter of 18 mm, a thickness of 5 mm, and a weight of 1.5 g was formed by applying a tableting pressure of 300 kgcm 2 to the mixed powder having the following composition.
• Example 6 (The agent produced in Example 4 was pulverized with an atomizer-pulverizer) Quenic acid 1 Sugar ester 1 part by weight Aspartame 0.05 part by weight Vitamin P 0.002 parts by weight Water 0.6 part by weight Lemon flavor Example 6
• the agent of the present invention (powder mixture) was produced using a universal mixer according to a standard method.
• Crystalline palatinose 8 4. Parts by weight (trade name Crystalline palatinose-IC)
• Example 5 Using the agent (tablet) produced in Example 5, a sugar-coated confection containing the agent of the present invention was produced.
• the agent (tablet) prepared in Example 5 was placed in a coating pan, and the syrup of the formulation (a) and the powdered reduced paraffin were alternately mixed in a ratio of 1: '2 ( (Weight ratio), followed by hard coating with a blend of (b). After coating, it was air-dried using room temperature air.
• Example 9 Using the agent (powder mixture) produced in Example 6, a beverage containing the agent of the present invention was produced. 25 g of the agent produced in Example 5 was dissolved in 200 mL of boiling water. Example 9
• a soft drink containing the agent of the present invention was produced with the following composition.
• the following ingredients were dissolved in 250 mL of hot water, and then filled into beverage cans (for 250 mL). 8 parts by weight of crystalline palatinose
• a hard candy containing the agent of the present invention was produced with the following composition. First, crystalline palatinose, trehalulose syrup and water were added to a dissolution tank, and the mixture was heated and stirred to dissolve. Next, they were heated under reduced pressure to a temperature of 120 ° C under a pressure of 700 mmHg, and citric acid, aspartame, vitamin P, and lemon flavor were mixed. After cooling to about 70-80 ° C, each grain was shaped so as to become 4 g and packaged individually. 70 parts by weight of crystalline palatinose
• a jelly drink (orange taste) containing the sustaining agent of the present invention was produced. First, mix the paratino sugar and water,
• Consumption and attention can be enhanced by taking the agent for maintaining concentration and attention of the present invention, and the concentration and attention can be maintained for a longer time and It is possible to maintain more constant.

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• Life Sciences & Earth Sciences (AREA)
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• 2001
  • 2001-07-24 JP JP2001223004A patent/JP4860840B2/ja not_active Expired - Lifetime
• 2002
  • 2002-05-10 EP EP02769566A patent/EP1393637B1/en not_active Expired - Lifetime
  • 2002-05-10 WO PCT/JP2002/004578 patent/WO2002091859A1/ja not_active Ceased
  • 2002-05-10 KR KR10-2003-7014728A patent/KR20030093354A/ko not_active Withdrawn
  • 2002-05-13 TW TW091109870A patent/TWI304326B/zh not_active IP Right Cessation
• 2003
  • 2003-11-04 GB GBGB0325696.3A patent/GB0325696D0/en active Pending

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