UY29116A1 - Un procedimiento de fabricacion de compuestos imidazolicos, sus sales y sus pseudopolimorfos - Google Patents

Un procedimiento de fabricacion de compuestos imidazolicos, sus sales y sus pseudopolimorfos

Info

Publication number
UY29116A1
UY29116A1 UY29116A UY29116A UY29116A1 UY 29116 A1 UY29116 A1 UY 29116A1 UY 29116 A UY29116 A UY 29116A UY 29116 A UY29116 A UY 29116A UY 29116 A1 UY29116 A1 UY 29116A1
Authority
UY
Uruguay
Prior art keywords
pseudopolimorphes
salts
procedure
manufacture
imidazolic
Prior art date
Application number
UY29116A
Other languages
English (en)
Inventor
Ines Petschen
Xavier Camps
Juan Sallares
Original Assignee
Ferrer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35295386&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UY29116(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ferrer Int filed Critical Ferrer Int
Publication of UY29116A1 publication Critical patent/UY29116A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/501,3-Diazoles; Hydrogenated 1,3-diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Catalysts (AREA)

Abstract

El procedimiento de fabricación de la presente invención consiste en la reacción por trasferencia defase de 1-(2,4-diclorofenil)-2-(1H-imidazol-I-il) con 3-bromometil-7-clorobenzo(b)tiofeno catalizada por sulfato ácido de tetrabutilamonio en tolueno y e presencia de hidróxido sódico. Por tratamiento del producto resultante con ácido nítrico en medio acuoso se obtiene el sertaconazol mononitrato monohidrato, el cual por calentamiento posterior proporciona el sertaconazol mononitrato.
UY29116A 2004-09-13 2005-09-13 Un procedimiento de fabricacion de compuestos imidazolicos, sus sales y sus pseudopolimorfos UY29116A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200402183A ES2249991B1 (es) 2004-09-13 2004-09-13 Procedimiento de fabricacion de compuestos imidazolicos, sus sales y sus pseudopolimorfos.

Publications (1)

Publication Number Publication Date
UY29116A1 true UY29116A1 (es) 2005-11-30

Family

ID=35295386

Family Applications (1)

Application Number Title Priority Date Filing Date
UY29116A UY29116A1 (es) 2004-09-13 2005-09-13 Un procedimiento de fabricacion de compuestos imidazolicos, sus sales y sus pseudopolimorfos

Country Status (24)

Country Link
US (1) US7829726B2 (es)
EP (1) EP1788876B1 (es)
JP (1) JP4866355B2 (es)
KR (1) KR100861436B1 (es)
CN (1) CN100579966C (es)
AR (1) AR053093A1 (es)
AT (1) ATE431076T1 (es)
AU (1) AU2005284331B2 (es)
BR (1) BRPI0515254A (es)
CA (1) CA2577253C (es)
DE (1) DE602005014491D1 (es)
DK (1) DK1788876T3 (es)
ES (1) ES2249991B1 (es)
HK (1) HK1104765A1 (es)
MX (1) MX2007002924A (es)
NO (1) NO337950B1 (es)
PA (1) PA8645401A1 (es)
PE (1) PE20060690A1 (es)
PL (1) PL1788876T3 (es)
PT (1) PT1788876E (es)
RU (1) RU2357965C2 (es)
TW (1) TWI357813B (es)
UY (1) UY29116A1 (es)
WO (1) WO2006029812A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0922851A2 (pt) * 2008-12-09 2015-12-29 Ferrer Int polimorfo ii de um compsoto antifúngico
US10437922B2 (en) * 2015-12-03 2019-10-08 Workday, Inc. Spreadsheet with unit based conversions
CN113501814A (zh) * 2021-07-30 2021-10-15 海南海神同洲制药有限公司 一种硝酸舍他康唑的纯化方法
CN113501815A (zh) * 2021-07-30 2021-10-15 海南海神同洲制药有限公司 一种硝酸舍他康唑晶型的制备方法
CN113816947A (zh) * 2021-08-25 2021-12-21 海南海神同洲制药有限公司 一种硝酸舍他康唑的重结晶方法
CN113735843B (zh) * 2021-09-07 2023-05-26 海南海神同洲制药有限公司 一种低熔点硝酸舍他康唑的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5135943A (en) * 1984-02-02 1992-08-04 Ferrer Internacional S.A. 1H-imidazole derivative compounds and pharmaceutical compositions containing the same
ES8504779A1 (es) 1984-02-02 1985-05-01 Ferrer Int Procedimiento de obtencion de nuevos derivados de 1h-imidazol
CA1250586A (en) * 1984-02-02 1989-02-28 Manuel Raga 1h-imidazole derivatives and process for their production
WO1996020939A1 (es) * 1995-01-04 1996-07-11 Ferrer Internacional, S.A. POLYMORFOS B Y C DE MONONITRATO DE 1-[2,4-DICLORO-β-[(7-CLOROBENZO[b]TIEN-3-IL)METOXI]FENETIL]IMIDAZOL
CN1191250C (zh) * 2001-09-26 2005-03-02 河北省药物研究所 一种硝酸舍他康唑的合成方法
ES2203316B1 (es) * 2002-02-11 2005-03-01 Ferrer Internacional, S.A. R-(-)-1-(2-(7-cloro-benzo(b)tiofen-3-il-metoxi)-2-(2,4-dicloro-fenil)-etil)1h-imidazol.

Also Published As

Publication number Publication date
BRPI0515254A (pt) 2008-07-15
TWI357813B (en) 2012-02-11
EP1788876A1 (en) 2007-05-30
ES2249991A1 (es) 2006-04-01
PA8645401A1 (es) 2006-06-02
WO2006029812A1 (en) 2006-03-23
DK1788876T3 (da) 2009-08-31
HK1104765A1 (en) 2008-01-25
NO337950B1 (no) 2016-07-18
PL1788876T3 (pl) 2009-11-30
ES2249991B1 (es) 2007-03-01
AU2005284331B2 (en) 2010-12-23
EP1788876B1 (en) 2009-05-13
JP2008512422A (ja) 2008-04-24
US20090005573A1 (en) 2009-01-01
KR100861436B1 (ko) 2008-10-02
AR053093A1 (es) 2007-04-25
NO20071818L (no) 2007-05-04
DE602005014491D1 (de) 2009-06-25
RU2007113922A (ru) 2008-10-20
PT1788876E (pt) 2009-08-17
JP4866355B2 (ja) 2012-02-01
TW200618799A (en) 2006-06-16
CA2577253A1 (en) 2006-03-23
CN100579966C (zh) 2010-01-13
AU2005284331A1 (en) 2006-03-23
RU2357965C2 (ru) 2009-06-10
ATE431076T1 (de) 2009-05-15
US7829726B2 (en) 2010-11-09
KR20070049663A (ko) 2007-05-11
MX2007002924A (es) 2007-06-15
CA2577253C (en) 2012-11-20
PE20060690A1 (es) 2006-07-11
CN101022727A (zh) 2007-08-22

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