ES2422161T3 - Procedimiento para producir 1-(3,4-diclorobencil)-5-octilbiguanida o una sal de la misma - Google Patents
Procedimiento para producir 1-(3,4-diclorobencil)-5-octilbiguanida o una sal de la mismaInfo
- Publication number
- ES2422161T3 ES2422161T3 ES07806580T ES07806580T ES2422161T3 ES 2422161 T3 ES2422161 T3 ES 2422161T3 ES 07806580 T ES07806580 T ES 07806580T ES 07806580 T ES07806580 T ES 07806580T ES 2422161 T3 ES2422161 T3 ES 2422161T3
- Authority
- ES
- Spain
- Prior art keywords
- salt
- formula
- dichlorobenzyl
- producing
- octylbiguanide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C277/02—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of guanidine from cyanamide, calcium cyanamide or dicyandiamides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/24—Y being a hetero atom
- C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Procedimiento para producir 1-(3,4-diclorobencil)-5-octilbiguanida representada por la fórmula (1):**Fórmula** o una sal de la misma, comprendiendo el procedimiento hacer reaccionar 1-ciano-3-octilguanidina representada porla fórmula (2):**Fórmula** o una sal de la misma, con 3,4-diclorobencilamina representada por la fórmula (3):**Fórmula** o una sal de la misma, en un solvente orgánico a base de éster.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006232922 | 2006-08-30 | ||
PCT/JP2007/067107 WO2008026757A1 (en) | 2006-08-30 | 2007-08-28 | Process for producing 1-(3,4-dichlorobenzyl)-5-octylbiguanide or a salt thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2422161T3 true ES2422161T3 (es) | 2013-09-09 |
Family
ID=38871529
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES07806580T Active ES2422161T3 (es) | 2006-08-30 | 2007-08-28 | Procedimiento para producir 1-(3,4-diclorobencil)-5-octilbiguanida o una sal de la misma |
Country Status (18)
Country | Link |
---|---|
US (1) | US7868207B2 (es) |
EP (1) | EP2066623B1 (es) |
JP (1) | JP5078993B2 (es) |
KR (1) | KR101087454B1 (es) |
CN (1) | CN101506152B (es) |
AR (1) | AR062576A1 (es) |
AU (1) | AU2007289597B2 (es) |
BR (1) | BRPI0715831A2 (es) |
CA (1) | CA2661272C (es) |
ES (1) | ES2422161T3 (es) |
HK (1) | HK1130468A1 (es) |
IL (1) | IL196982A (es) |
MX (1) | MX2009002258A (es) |
MY (1) | MY146360A (es) |
RU (1) | RU2440978C2 (es) |
TW (1) | TWI385143B (es) |
WO (1) | WO2008026757A1 (es) |
ZA (1) | ZA200900838B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2630920A1 (en) | 2005-11-22 | 2007-05-31 | University Of South Florida | Inhibition of cell proliferation |
US20100184851A1 (en) * | 2008-08-29 | 2010-07-22 | University Of South Florida | Inhibition of cell proliferation |
ES2734299T3 (es) * | 2015-09-11 | 2019-12-05 | Bayer Cropscience Ag | Procedimiento para producir sales de biguanida y s-triazinas |
JPWO2021132365A1 (es) * | 2019-12-26 | 2021-07-01 | ||
CN113874349B (zh) * | 2019-12-26 | 2024-09-13 | 株式会社力森诺科 | 高聚合性n-乙烯基羧酸酰胺单体的制造方法 |
WO2021132363A1 (ja) * | 2019-12-26 | 2021-07-01 | 昭和電工株式会社 | 高重合性n-ビニルカルボン酸アミド単量体の製造方法 |
CN113939496A (zh) * | 2019-12-26 | 2022-01-14 | 昭和电工株式会社 | 高聚合性n-乙烯基羧酸酰胺单体的制造方法 |
CN113939497A (zh) * | 2019-12-26 | 2022-01-14 | 昭和电工株式会社 | 高聚合性n-乙烯基羧酸酰胺单体的制造方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5286905A (en) * | 1990-12-28 | 1994-02-15 | Idemitsu Kosan Company Limited | Process for producing biguanide derivative |
JPH04308562A (ja) * | 1991-04-05 | 1992-10-30 | Otsuka Pharmaceut Co Ltd | ビスビグアナイド誘導体とこの誘導体を含有した消毒薬 |
CA2064664C (en) | 1991-04-05 | 2000-01-11 | Hiroshi Ishikawa | Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives |
JP2662343B2 (ja) * | 1991-06-19 | 1997-10-08 | 大塚製薬株式会社 | モノビグアナイド誘導体とこの誘導体を含有した消毒薬 |
JP3493692B2 (ja) * | 1993-09-09 | 2004-02-03 | 三菱マテリアル株式会社 | ビスビグアナイド系化合物およびそれを含む殺菌剤 |
AU2004243183B2 (en) * | 2003-05-28 | 2009-08-06 | Otsuka Pharmaceutical Co., Ltd. | Aqueous olanexidine solution, method of preparing the same, and disinfectant |
-
2007
- 2007-08-28 CN CN2007800317486A patent/CN101506152B/zh not_active Expired - Fee Related
- 2007-08-28 JP JP2009509802A patent/JP5078993B2/ja not_active Expired - Fee Related
- 2007-08-28 WO PCT/JP2007/067107 patent/WO2008026757A1/en active Application Filing
- 2007-08-28 AU AU2007289597A patent/AU2007289597B2/en not_active Ceased
- 2007-08-28 BR BRPI0715831-9A patent/BRPI0715831A2/pt not_active IP Right Cessation
- 2007-08-28 US US12/439,481 patent/US7868207B2/en not_active Expired - Fee Related
- 2007-08-28 TW TW096131817A patent/TWI385143B/zh not_active IP Right Cessation
- 2007-08-28 CA CA2661272A patent/CA2661272C/en not_active Expired - Fee Related
- 2007-08-28 KR KR1020097006445A patent/KR101087454B1/ko not_active IP Right Cessation
- 2007-08-28 EP EP07806580.2A patent/EP2066623B1/en not_active Not-in-force
- 2007-08-28 MX MX2009002258A patent/MX2009002258A/es active IP Right Grant
- 2007-08-28 ZA ZA200900838A patent/ZA200900838B/xx unknown
- 2007-08-28 MY MYPI20090486A patent/MY146360A/en unknown
- 2007-08-28 RU RU2009111276/04A patent/RU2440978C2/ru not_active IP Right Cessation
- 2007-08-28 ES ES07806580T patent/ES2422161T3/es active Active
- 2007-08-29 AR ARP070103824A patent/AR062576A1/es unknown
-
2009
- 2009-02-09 IL IL196982A patent/IL196982A/en active IP Right Grant
- 2009-11-09 HK HK09110398.8A patent/HK1130468A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ZA200900838B (en) | 2010-05-26 |
TWI385143B (zh) | 2013-02-11 |
KR20090045409A (ko) | 2009-05-07 |
AU2007289597B2 (en) | 2011-03-03 |
AR062576A1 (es) | 2008-11-19 |
CA2661272A1 (en) | 2008-03-06 |
US7868207B2 (en) | 2011-01-11 |
RU2009111276A (ru) | 2010-10-10 |
AU2007289597A1 (en) | 2008-03-06 |
CA2661272C (en) | 2014-03-18 |
IL196982A (en) | 2013-03-24 |
BRPI0715831A2 (pt) | 2013-07-23 |
HK1130468A1 (es) | 2009-12-31 |
TW200817316A (en) | 2008-04-16 |
MY146360A (en) | 2012-08-15 |
RU2440978C2 (ru) | 2012-01-27 |
EP2066623A1 (en) | 2009-06-10 |
CN101506152B (zh) | 2012-11-21 |
KR101087454B1 (ko) | 2011-11-25 |
US20090270653A1 (en) | 2009-10-29 |
EP2066623B1 (en) | 2013-06-19 |
JP5078993B2 (ja) | 2012-11-21 |
MX2009002258A (es) | 2009-03-20 |
CN101506152A (zh) | 2009-08-12 |
JP2010502567A (ja) | 2010-01-28 |
IL196982A0 (en) | 2009-11-18 |
WO2008026757A1 (en) | 2008-03-06 |
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