AR057305A1 - Proceso para la preparacion de derivados de sulfamida - Google Patents
Proceso para la preparacion de derivados de sulfamidaInfo
- Publication number
- AR057305A1 AR057305A1 ARP060102055A ARP060102055A AR057305A1 AR 057305 A1 AR057305 A1 AR 057305A1 AR P060102055 A ARP060102055 A AR P060102055A AR P060102055 A ARP060102055 A AR P060102055A AR 057305 A1 AR057305 A1 AR 057305A1
- Authority
- AR
- Argentina
- Prior art keywords
- preparation
- sulfamide
- sulfamide derivatives
- sulfonylimine
- organic solvent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/04—Diamides of sulfuric acids
- C07C307/06—Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/34—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfuric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/96—Sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/02—Acyclic radicals
Abstract
Un proceso para la preparacion de un derivado de sulfamida, que comprende hacer reaccionar un aldehido con una sulfamida sustituida o no sustituida, en presencia de un ácido o TMCI, en un disolvente orgánico adecuado, para proporcionar la sulfonilimina correspondiente; reducir o hidrogenar la sulfonilimina, en un disolvente orgánico adecuado, para proporcionar el derivado de sulfamida correspondiente.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68315105P | 2005-05-20 | 2005-05-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR057305A1 true AR057305A1 (es) | 2007-11-28 |
Family
ID=36716875
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP060102055A AR057305A1 (es) | 2005-05-20 | 2006-05-19 | Proceso para la preparacion de derivados de sulfamida |
Country Status (16)
Country | Link |
---|---|
US (1) | US8283478B2 (es) |
EP (1) | EP1881959A1 (es) |
JP (1) | JP2008545650A (es) |
KR (1) | KR20080012360A (es) |
CN (1) | CN101754947A (es) |
AR (1) | AR057305A1 (es) |
AU (1) | AU2006249577A1 (es) |
BR (1) | BRPI0610864A2 (es) |
CA (1) | CA2609185A1 (es) |
EA (1) | EA200702558A1 (es) |
IL (1) | IL187458A0 (es) |
MX (1) | MX2007014613A (es) |
NO (1) | NO20076462L (es) |
PE (1) | PE20061450A1 (es) |
TW (1) | TW200716525A (es) |
WO (1) | WO2006127184A1 (es) |
Families Citing this family (23)
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AR049646A1 (es) * | 2004-06-16 | 2006-08-23 | Janssen Pharmaceutica Nv | Derivados de sulfamato y sulfamida utiles para el tratamiento de la epilepsia y trastornos relacionados |
MY147767A (en) | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
MY142329A (en) * | 2004-08-24 | 2010-11-15 | Janssen Pharmaceutica Nv | Novel benzo-fused heteroaryl sulfamide derivatives useful as anticonvulsant agents. |
AU2006249577A1 (en) | 2005-05-20 | 2006-11-30 | Janssen Pharmaceutica N.V. | Process for preparation of sulfamide derivatives |
US8691867B2 (en) * | 2005-12-19 | 2014-04-08 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction |
US20070155823A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives as neuroprotective agents |
AR058389A1 (es) * | 2005-12-19 | 2008-01-30 | Janssen Pharmaceutica Nv | Uso de derivados heterociclicos benzo-fusionados de sulfamida para el tratamiento de la obesidad |
US8716231B2 (en) * | 2005-12-19 | 2014-05-06 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain |
US20070155827A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression |
US8497298B2 (en) * | 2005-12-19 | 2013-07-30 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels |
US8937096B2 (en) * | 2005-12-19 | 2015-01-20 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder |
US20070191449A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of Benzo-Heteroaryl Sulfamide Derivatives for the Treatment of Depression |
US20070191474A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of migraine |
US20070191459A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of Benzo-Heteroaryl Sulfamide Derivatives for Lowering Lipids and Lowering Blood Glucose Levels |
TW200738669A (en) * | 2006-02-22 | 2007-10-16 | Janssen Pharmaceutica Nv | Crystalline forms of N-(benzo[b]thien-3-ylmethyl)-sulfamide |
AU2007253814A1 (en) * | 2006-05-19 | 2007-11-29 | Janssen Pharmaceutica N.V. | Co-therapy for the treatment of epilepsy |
CN100548979C (zh) * | 2007-01-12 | 2009-10-14 | 中国科学院上海有机化学研究所 | 一种合成3-甲氨基吲哚化合物的方法 |
US20090247616A1 (en) * | 2008-03-26 | 2009-10-01 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of anxiety |
US20090247617A1 (en) * | 2008-03-26 | 2009-10-01 | Abdel-Magid Ahmed F | Process for the preparation of benzo-fused heteroaryl sulfamates |
EA018567B1 (ru) | 2008-06-23 | 2013-08-30 | Янссен Фармацевтика Нв | Кристаллическая форма (2s)-(-)-n-(6-хлор-2,3-дигидробензо[1,4]диоксин-2-илметил)сульфамида |
US8815939B2 (en) * | 2008-07-22 | 2014-08-26 | Janssen Pharmaceutica Nv | Substituted sulfamide derivatives |
US8609849B1 (en) | 2010-11-30 | 2013-12-17 | Fox Chase Chemical Diversity Center, Inc. | Hydroxylated sulfamides exhibiting neuroprotective action and their method of use |
CN102976953A (zh) * | 2011-09-05 | 2013-03-20 | 上海药明康德新药开发有限公司 | 手性α-二氟甲基苯基乙胺的制备方法 |
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-
2006
- 2006-04-19 AU AU2006249577A patent/AU2006249577A1/en not_active Abandoned
- 2006-04-19 EA EA200702558A patent/EA200702558A1/ru unknown
- 2006-04-19 CN CN200680026669A patent/CN101754947A/zh active Pending
- 2006-04-19 WO PCT/US2006/014766 patent/WO2006127184A1/en active Application Filing
- 2006-04-19 US US11/406,794 patent/US8283478B2/en not_active Expired - Fee Related
- 2006-04-19 EP EP06750739A patent/EP1881959A1/en not_active Withdrawn
- 2006-04-19 MX MX2007014613A patent/MX2007014613A/es not_active Application Discontinuation
- 2006-04-19 KR KR1020077029126A patent/KR20080012360A/ko not_active Application Discontinuation
- 2006-04-19 CA CA002609185A patent/CA2609185A1/en not_active Abandoned
- 2006-04-19 BR BRPI0610864-4A patent/BRPI0610864A2/pt not_active Application Discontinuation
- 2006-04-19 JP JP2008512290A patent/JP2008545650A/ja not_active Withdrawn
- 2006-05-19 PE PE2006000529A patent/PE20061450A1/es not_active Application Discontinuation
- 2006-05-19 AR ARP060102055A patent/AR057305A1/es not_active Application Discontinuation
- 2006-05-19 TW TW095117749A patent/TW200716525A/zh unknown
-
2007
- 2007-11-18 IL IL187458A patent/IL187458A0/en unknown
- 2007-12-14 NO NO20076462A patent/NO20076462L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN101754947A (zh) | 2010-06-23 |
NO20076462L (no) | 2008-02-08 |
PE20061450A1 (es) | 2007-01-16 |
US8283478B2 (en) | 2012-10-09 |
EA200702558A1 (ru) | 2008-06-30 |
TW200716525A (en) | 2007-05-01 |
BRPI0610864A2 (pt) | 2010-08-03 |
MX2007014613A (es) | 2008-04-02 |
JP2008545650A (ja) | 2008-12-18 |
KR20080012360A (ko) | 2008-02-11 |
WO2006127184A1 (en) | 2006-11-30 |
CA2609185A1 (en) | 2006-11-30 |
AU2006249577A1 (en) | 2006-11-30 |
IL187458A0 (en) | 2008-03-20 |
EP1881959A1 (en) | 2008-01-30 |
US20060270856A1 (en) | 2006-11-30 |
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