UA80396C2 - Use of il-18 inhibitors for treating or traumatic head injury - Google Patents
Use of il-18 inhibitors for treating or traumatic head injury Download PDFInfo
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- UA80396C2 UA80396C2 UA20031212328A UA20031212328A UA80396C2 UA 80396 C2 UA80396 C2 UA 80396C2 UA 20031212328 A UA20031212328 A UA 20031212328A UA 20031212328 A UA20031212328 A UA 20031212328A UA 80396 C2 UA80396 C2 UA 80396C2
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- damage
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- injury
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A—HUMAN NECESSITIES
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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Landscapes
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- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01112067 | 2001-05-25 | ||
| PCT/EP2002/005666 WO2002096456A1 (en) | 2001-05-25 | 2002-05-23 | Use of il-18 inhibitors for treating or preventing cns injuries |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA80396C2 true UA80396C2 (en) | 2007-09-25 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA20031212328A UA80396C2 (en) | 2001-05-25 | 2002-05-23 | Use of il-18 inhibitors for treating or traumatic head injury |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US7655616B2 (ja) |
| EP (1) | EP1390070B1 (ja) |
| JP (1) | JP4344142B2 (ja) |
| KR (1) | KR20040030625A (ja) |
| CN (1) | CN1305529C (ja) |
| AU (1) | AU2002314103B2 (ja) |
| BG (1) | BG66395B1 (ja) |
| BR (1) | BR0210007A (ja) |
| CA (1) | CA2445664C (ja) |
| CY (1) | CY1119190T1 (ja) |
| CZ (1) | CZ307321B6 (ja) |
| DK (1) | DK1390070T3 (ja) |
| EA (1) | EA006744B1 (ja) |
| EE (1) | EE05263B1 (ja) |
| ES (1) | ES2617084T3 (ja) |
| HK (1) | HK1069762A1 (ja) |
| HR (1) | HRP20030842B1 (ja) |
| HU (1) | HU230294B1 (ja) |
| IL (2) | IL159014A0 (ja) |
| LT (1) | LT1390070T (ja) |
| ME (1) | ME00550B (ja) |
| MX (1) | MXPA03010743A (ja) |
| NO (1) | NO331882B1 (ja) |
| PL (1) | PL216228B1 (ja) |
| PT (1) | PT1390070T (ja) |
| RS (1) | RS56006B1 (ja) |
| SK (1) | SK288413B6 (ja) |
| UA (1) | UA80396C2 (ja) |
| WO (1) | WO2002096456A1 (ja) |
| ZA (1) | ZA200308172B (ja) |
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| CA2524403C (en) | 2003-05-13 | 2013-07-09 | Applied Research Systems Ars Holding N.V. | Active variants of the il-18 binding protein and medical uses thereof |
| US20090004683A1 (en) * | 2004-06-30 | 2009-01-01 | Atsuo Sekiyama | Indicator Agent for Noninflammatory Stress Response and Use Thereof |
| US7691611B2 (en) | 2005-06-03 | 2010-04-06 | Ares Trading S.A. | Production of recombinant IL-18 binding protein |
| ES2376534T3 (es) * | 2005-06-03 | 2012-03-14 | Merck Serono Sa | Uso de isoformas de il-18bp para el tratamiento y/o prevención de enfermedades inflamatorias neurológicas. |
| JP5091127B2 (ja) | 2005-06-10 | 2012-12-05 | アレス トレーディング ソシエテ アノニム | Ｉｌ−１８結合タンパク質の精製のための方法 |
| US8685400B2 (en) | 2007-07-30 | 2014-04-01 | University Of Miami | Modulating inflammasome activity and inflammation in the central nervous system |
| EP3978526A1 (en) * | 2013-09-05 | 2022-04-06 | AB2 Bio SA | Il-18 binding protein (il-18bp) in inflammatory diseases |
| US10882905B2 (en) | 2015-03-05 | 2021-01-05 | Ab2 Bio Sa | IL-18 binding protein (IL-18BP) and antibodies in inflammatory diseases |
Family Cites Families (8)
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| JPH0873453A (ja) * | 1994-09-02 | 1996-03-19 | Otsuka Pharmaceut Co Ltd | サイトカイン阻害剤 |
| IL121860A0 (en) * | 1997-08-14 | 1998-02-22 | Yeda Res & Dev | Interleukin-18 binding proteins their preparation and use |
| WO1999046248A1 (en) * | 1998-03-09 | 1999-09-16 | Vertex Pharmaceuticals Incorporated | 1,2-diazepane derivatives as interleukin-1beta converting enzyme inhibitors |
| CA2276216A1 (en) * | 1998-06-24 | 1999-12-24 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | An artificial peptide capable of neutralizing the biological activity of interleukin-18 |
| CN1250286C (zh) * | 2000-05-05 | 2006-04-12 | 应用研究系统Ars股份公司 | Il－18抑制剂在治疗和/或预防动脉粥样硬化中的应用 |
| DE60106026T2 (de) * | 2000-06-23 | 2006-02-23 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | 2-arachidonylglycerol (2-ag)-ein hemmer des tumor nekrose faktors-alfa und neuroprotektor des gehirns bei geschlossenen kopfverletzungen |
| AU2002224417A1 (en) * | 2000-10-18 | 2002-04-29 | Immunex Corporation | Methods for treating il-18 mediated disorders |
| US6671553B1 (en) * | 2001-05-23 | 2003-12-30 | Pacesetter, Inc. | Implantable cardiac lead having terminating connector strain relief and method of manufacture |
-
2002
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