UA80171C2 - Pyrrolopyrimidine derivatives - Google Patents
Pyrrolopyrimidine derivatives Download PDFInfo
- Publication number
- UA80171C2 UA80171C2 UAA200506094A UA2005006094A UA80171C2 UA 80171 C2 UA80171 C2 UA 80171C2 UA A200506094 A UAA200506094 A UA A200506094A UA 2005006094 A UA2005006094 A UA 2005006094A UA 80171 C2 UA80171 C2 UA 80171C2
- Authority
- UA
- Ukraine
- Prior art keywords
- amino
- pyrrolo
- carbonyl
- isopropyl
- phenyl
- Prior art date
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Classifications
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A—HUMAN NECESSITIES
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
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- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Diabetes (AREA)
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- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43456802P | 2002-12-19 | 2002-12-19 | |
| PCT/IB2003/005841 WO2004056830A1 (en) | 2002-12-19 | 2003-12-08 | Pyrrolopyrimidine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA80171C2 true UA80171C2 (en) | 2007-08-27 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200506094A UA80171C2 (en) | 2002-12-19 | 2003-08-12 | Pyrrolopyrimidine derivatives |
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| EP (1) | EP1578751B1 (ru) |
| JP (1) | JP4057013B2 (ru) |
| KR (2) | KR20070087020A (ru) |
| CN (1) | CN1726218A (ru) |
| AP (1) | AP2005003342A0 (ru) |
| AR (1) | AR042509A1 (ru) |
| AT (1) | ATE512965T1 (ru) |
| AU (1) | AU2003286317A1 (ru) |
| BR (1) | BR0317524A (ru) |
| CA (1) | CA2510853C (ru) |
| EA (1) | EA200500814A1 (ru) |
| EC (1) | ECSP055867A (ru) |
| ES (1) | ES2364649T3 (ru) |
| GT (1) | GT200300289A (ru) |
| HN (1) | HN2003000416A (ru) |
| HR (1) | HRP20050560A2 (ru) |
| IS (1) | IS7872A (ru) |
| MA (1) | MA27568A1 (ru) |
| MX (1) | MXPA05006793A (ru) |
| NL (1) | NL1025068C2 (ru) |
| NO (1) | NO20052802L (ru) |
| NZ (1) | NZ540456A (ru) |
| OA (1) | OA12976A (ru) |
| PA (1) | PA8591701A1 (ru) |
| PE (1) | PE20040914A1 (ru) |
| PL (1) | PL377774A1 (ru) |
| RS (1) | RS20050469A (ru) |
| TN (1) | TNSN05165A1 (ru) |
| TW (1) | TW200423939A (ru) |
| UA (1) | UA80171C2 (ru) |
| UY (1) | UY28132A1 (ru) |
| WO (1) | WO2004056830A1 (ru) |
| ZA (1) | ZA200504440B (ru) |
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| AU2004282219C1 (en) * | 2003-10-15 | 2009-12-17 | Osi Pharmaceuticals, Inc. | Imidazo [1, 5 - a] pyrazine tyrosine kinase inhibitors |
| JP2007511596A (ja) | 2003-11-17 | 2007-05-10 | ファイザー・プロダクツ・インク | 癌の治療において有用なピロロピリミジン化合物 |
| SG163576A1 (en) | 2004-04-02 | 2010-08-30 | Osi Pharm Inc | 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors |
| CA2566160C (en) * | 2004-05-27 | 2011-01-18 | Pfizer Products Inc. | Pyrrolopyrimidine derivatives useful in cancer treatment |
| AR053090A1 (es) * | 2004-07-20 | 2007-04-25 | Osi Pharm Inc | Imidazotriazinas como inhibidores de proteina quinasas y su uso para la preparacion de medicamentos |
| WO2006076592A1 (en) | 2005-01-14 | 2006-07-20 | Cgi Pharmaceuticals, Inc. | 1,3 substituted diaryl ureas as modulators of kinase activity |
| US20070287719A1 (en) * | 2005-03-11 | 2007-12-13 | Pfizer Inc | Salts, Prodrugs and Formulations of 1-[5-(4-Amino-7-Isopropyl-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carbonyl)-2-Methoxy-Phenyl]-3-(2,4-Dichloro-Phenyl)-Urea |
| WO2007024294A2 (en) | 2005-05-03 | 2007-03-01 | Cgi Pharmaceuticals, Inc. | Certain substituted ureas, as modulators of kinase activity |
| US7795248B2 (en) | 2005-05-18 | 2010-09-14 | Abbott Laboratories, Inc. | Substituted 7,8-dihydro-1H-pyrimido[4,5-B][1,4]diazepin-4-amines are novel kinase inhibitors |
| DE102005037499A1 (de) * | 2005-08-09 | 2007-02-15 | Merck Patent Gmbh | Pyrazolderivate |
| US20070049592A1 (en) * | 2005-08-22 | 2007-03-01 | Geuns-Meyer Stephanie D | Bis-aryl urea compounds and methods of use |
| ES2332423T3 (es) * | 2005-10-28 | 2010-02-04 | Irm Llc | Compuestos y composiciones como inhibidores de proteina quinasas. |
| SI1951724T1 (sl) * | 2005-11-17 | 2011-09-30 | Osi Pharmaceuticals Llc | Kondenzirani biciklični mTOR inhibitorji |
| US20070135387A1 (en) * | 2005-12-08 | 2007-06-14 | Michaelides Michael R | Inhibitors of protein kinases |
| WO2007066189A2 (en) * | 2005-12-09 | 2007-06-14 | Pfizer Products Inc. | Salts, prodrugs and formulations of 1-[5-(4-amino-7-isopropyl-7h-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-2-methoxy-phenyl]-3-(2,4-dichloro-phenyl)-urea |
| US8575164B2 (en) * | 2005-12-19 | 2013-11-05 | OSI Pharmaceuticals, LLC | Combination cancer therapy |
| JP2009520028A (ja) * | 2005-12-19 | 2009-05-21 | オーエスアイ・ファーマスーティカルズ・インコーポレーテッド | Ｉｇｆｒ抑制剤および抗癌剤の併用 |
| EP1973917B1 (en) * | 2005-12-29 | 2015-06-10 | AbbVie Inc. | Protein kinase inhibitors |
| WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
| ME01507B (me) | 2006-11-22 | 2014-04-20 | Incyte Holdings Corp | Imidazotriazini i imidazopirimidini kao inhibitori kinaze |
| WO2008076143A1 (en) * | 2006-12-18 | 2008-06-26 | Osi Pharmaceuticals, Inc. | Combination of igfr inhibitor and anti-cancer agent |
| WO2009012283A1 (en) | 2007-07-17 | 2009-01-22 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
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