UA64784C2 - Improvements in enzymatic synthesis of chiral amines - Google Patents

Improvements in enzymatic synthesis of chiral amines Download PDF

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Publication number
UA64784C2
UA64784C2 UA2000105759A UA2000105759A UA64784C2 UA 64784 C2 UA64784 C2 UA 64784C2 UA 2000105759 A UA2000105759 A UA 2000105759A UA 2000105759 A UA2000105759 A UA 2000105759A UA 64784 C2 UA64784 C2 UA 64784C2
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UA
Ukraine
Prior art keywords
aminopropane
amino
amino group
transaminase
acid
Prior art date
Application number
UA2000105759A
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English (en)
Ukrainian (uk)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed filed Critical
Publication of UA64784C2 publication Critical patent/UA64784C2/uk

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/001Amines; Imines
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/005Amino acids other than alpha- or beta amino acids, e.g. gamma amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/06Alanine; Leucine; Isoleucine; Serine; Homoserine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/12Methionine; Cysteine; Cystine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
UA2000105759A 1998-03-11 1999-10-03 Improvements in enzymatic synthesis of chiral amines UA64784C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7752098P 1998-03-11 1998-03-11
PCT/US1999/005150 WO1999046398A1 (en) 1998-03-11 1999-03-10 Improvements in the enzymatic synthesis of chiral amines

Publications (1)

Publication Number Publication Date
UA64784C2 true UA64784C2 (en) 2004-03-15

Family

ID=22138554

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2000105759A UA64784C2 (en) 1998-03-11 1999-10-03 Improvements in enzymatic synthesis of chiral amines

Country Status (24)

Country Link
EP (1) EP1075534B8 (es)
JP (1) JP2002505884A (es)
KR (1) KR20010034561A (es)
CN (1) CN1154746C (es)
AT (1) ATE295424T1 (es)
AU (1) AU753904B2 (es)
BR (1) BR9908797A (es)
CA (1) CA2322605A1 (es)
CZ (1) CZ295882B6 (es)
DE (1) DE69925267T2 (es)
ES (1) ES2243051T3 (es)
FI (1) FI20001805A (es)
HK (1) HK1035000A1 (es)
HU (1) HUP0101056A3 (es)
MX (1) MXPA00008573A (es)
NO (1) NO319671B1 (es)
NZ (1) NZ506405A (es)
PL (1) PL342882A1 (es)
PT (1) PT1075534E (es)
RU (1) RU2213142C2 (es)
SK (1) SK284352B6 (es)
TR (1) TR200002604T2 (es)
UA (1) UA64784C2 (es)
WO (1) WO1999046398A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE277170T1 (de) 1999-03-19 2004-10-15 Sumitomo Chemical Co Stereoselektive transaminase, deren kodierende gen und deren verwendungen
JP2001190298A (ja) * 2000-01-13 2001-07-17 Kanegafuchi Chem Ind Co Ltd 光学活性n−メチルアミノ酸の製造方法
EP1818411A1 (en) * 2006-02-13 2007-08-15 Lonza AG Process for the preparation of optically active chiral amines
DE102007042600A1 (de) 2007-09-07 2009-03-12 Evonik Degussa Gmbh Verfahren zur Herstellung von enantiomerenangereichten Aminen
EP2385983B1 (en) 2009-01-08 2017-12-20 Codexis, Inc. Transaminase polypeptides
JP5707344B2 (ja) 2009-02-26 2015-04-30 コデクシス, インコーポレイテッド トランスアミナーゼ生体触媒
US8921079B2 (en) 2009-06-22 2014-12-30 Codexis, Inc. Transaminase reactions
ES2562458T3 (es) * 2009-09-02 2016-03-04 Lonza Ag Proceso de identificación y preparación de una transaminasa omega específica de (R)
WO2011159910A2 (en) 2010-06-17 2011-12-22 Codexis, Inc. Biocatalysts and methods for the synthesis of (s)-3-(1-aminoethyl)-phenol
EP2606139B1 (en) 2010-08-16 2015-07-15 Codexis, Inc. Biocatalysts and methods for the synthesis of (1r,2r)-2-(3,4-dimethoxyphenethoxy)cyclohexanamine
WO2013024453A1 (en) * 2011-08-16 2013-02-21 Embio Limited Enzymatic synthesis of optically active chiral amines
CN104630170A (zh) * 2013-11-08 2015-05-20 中国科学院天津工业生物技术研究所 一种来源于里氏木霉的新(r)-转氨酶及其应用
CN114134126B (zh) * 2021-10-28 2023-12-05 浙江大学杭州国际科创中心 转氨酶及其突变体在制备(s)-1-甲氧基-2-丙胺中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300437A (en) * 1989-06-22 1994-04-05 Celgene Corporation Enantiomeric enrichment and stereoselective synthesis of chiral amines
DE69635082T2 (de) * 1995-10-23 2006-06-01 Kaneka Corp. Verfahren zur herstellung optisch aktiver aminoverbindungen

Also Published As

Publication number Publication date
SK284352B6 (sk) 2005-02-04
RU2213142C2 (ru) 2003-09-27
KR20010034561A (ko) 2001-04-25
DE69925267D1 (de) 2005-06-16
EP1075534A1 (en) 2001-02-14
CN1154746C (zh) 2004-06-23
CA2322605A1 (en) 1999-09-16
HUP0101056A2 (hu) 2001-07-30
EP1075534B8 (en) 2005-07-06
ATE295424T1 (de) 2005-05-15
AU753904B2 (en) 2002-10-31
PT1075534E (pt) 2005-09-30
NO319671B1 (no) 2005-09-05
NO20004036D0 (no) 2000-08-11
BR9908797A (pt) 2000-12-12
JP2002505884A (ja) 2002-02-26
PL342882A1 (en) 2001-07-16
ES2243051T3 (es) 2005-11-16
AU2993899A (en) 1999-09-27
WO1999046398A1 (en) 1999-09-16
EP1075534B1 (en) 2005-05-11
FI20001805A (fi) 2000-08-15
CN1292828A (zh) 2001-04-25
CZ20003177A3 (cs) 2000-12-13
DE69925267T2 (de) 2006-01-26
CZ295882B6 (cs) 2005-11-16
NO20004036L (no) 2000-10-27
EP1075534A4 (en) 2003-07-09
HUP0101056A3 (en) 2006-03-28
HK1035000A1 (en) 2001-11-09
MXPA00008573A (es) 2003-07-14
SK13382000A3 (sk) 2001-05-10
NZ506405A (en) 2003-08-29
TR200002604T2 (tr) 2000-11-21

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