UA61970C2 - Combined use of tyrosine kinase inhibitor and a chemical castration agent for treating prostate cancer - Google Patents
Combined use of tyrosine kinase inhibitor and a chemical castration agent for treating prostate cancer Download PDFInfo
- Publication number
- UA61970C2 UA61970C2 UA2000031438A UA2000031438A UA61970C2 UA 61970 C2 UA61970 C2 UA 61970C2 UA 2000031438 A UA2000031438 A UA 2000031438A UA 2000031438 A UA2000031438 A UA 2000031438A UA 61970 C2 UA61970 C2 UA 61970C2
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- Prior art keywords
- tyrosine kinase
- compound
- kinase inhibitor
- differs
- specified
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- A—HUMAN NECESSITIES
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
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- Engineering & Computer Science (AREA)
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- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US5589197P | 1997-08-15 | 1997-08-15 | |
PCT/US1998/016849 WO1999008668A2 (en) | 1997-08-15 | 1998-08-13 | Combination of tyrosine kinase inhibitor and chemical castration to treat prostate cancer |
Publications (1)
Publication Number | Publication Date |
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UA61970C2 true UA61970C2 (en) | 2003-12-15 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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UA2000031438A UA61970C2 (en) | 1997-08-15 | 1998-08-13 | Combined use of tyrosine kinase inhibitor and a chemical castration agent for treating prostate cancer |
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US (1) | US5985877A (ru) |
EP (1) | EP1011648B2 (ru) |
JP (1) | JP2001515032A (ru) |
KR (1) | KR100612161B1 (ru) |
CN (1) | CN1147317C (ru) |
AT (1) | ATE208210T1 (ru) |
AU (1) | AU737092B2 (ru) |
BR (1) | BR9812122A (ru) |
CA (1) | CA2299471C (ru) |
CZ (1) | CZ297198B6 (ru) |
DE (1) | DE69802422T3 (ru) |
DK (1) | DK1011648T4 (ru) |
EA (1) | EA002525B1 (ru) |
ES (1) | ES2163293T5 (ru) |
HK (1) | HK1028565A1 (ru) |
HU (1) | HUP0003194A3 (ru) |
NO (1) | NO325526B1 (ru) |
NZ (2) | NZ517497A (ru) |
PL (1) | PL193375B1 (ru) |
PT (1) | PT1011648E (ru) |
TR (1) | TR200000415T2 (ru) |
UA (1) | UA61970C2 (ru) |
WO (1) | WO1999008668A2 (ru) |
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AU6004999A (en) * | 1998-10-08 | 2000-04-26 | Takeda Chemical Industries Ltd. | Agents for retarding change of hormone-dependent cancer into hormone-independentcancer |
GB0007371D0 (en) * | 2000-03-28 | 2000-05-17 | Astrazeneca Uk Ltd | Chemical compounds |
GB0008368D0 (en) * | 2000-04-06 | 2000-05-24 | Astrazeneca Ab | Combination product |
US20020169154A1 (en) * | 2001-04-04 | 2002-11-14 | Cephalon, Inc. | Novel methods and compositions involving trk tyrosine kinase inhibitors and antineoplastic agents |
CN1507355A (zh) * | 2001-05-08 | 2004-06-23 | Ĭ��ר������˾ | 使用抗egfr抗体和抗激素剂的联合疗法 |
SE0101697D0 (sv) * | 2001-05-14 | 2001-05-14 | Astrazeneca Ab | Pharmaceutical combination |
IL144583A0 (en) | 2001-07-26 | 2002-05-23 | Peptor Ltd | Chimeric protein kinase inhibitors |
CA2458452C (en) * | 2001-08-10 | 2011-04-19 | Takeda Chemical Industries, Ltd. | Gnrh agonist combination drugs |
WO2003018611A2 (en) * | 2001-08-24 | 2003-03-06 | University Of Victoria Innovation And Development Corporation | Proaerolysin containing protease activation sequences and methods of use for treatment of prostate cancer |
US7132100B2 (en) | 2002-06-14 | 2006-11-07 | Medimmune, Inc. | Stabilized liquid anti-RSV antibody formulations |
US7425618B2 (en) | 2002-06-14 | 2008-09-16 | Medimmune, Inc. | Stabilized anti-respiratory syncytial virus (RSV) antibody formulations |
US7563810B2 (en) | 2002-11-06 | 2009-07-21 | Celgene Corporation | Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases |
US8034831B2 (en) | 2002-11-06 | 2011-10-11 | Celgene Corporation | Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies |
CA2521826C (en) | 2003-04-11 | 2013-08-06 | Jennifer L. Reed | Recombinant il-9 antibodies and uses thereof |
US20040224000A1 (en) * | 2003-05-05 | 2004-11-11 | Romano Deghenghi | Implants for non-radioactive brachytherapy of hormonal-insensitive cancers |
IL156429A0 (en) * | 2003-06-12 | 2004-01-04 | Peptor Ltd | Cell permeable conjugates of peptides for inhibition of protein kinases |
CA2536238C (en) | 2003-08-18 | 2015-04-07 | Medimmune, Inc. | Humanization of antibodies |
WO2006047639A2 (en) | 2004-10-27 | 2006-05-04 | Medimmune, Inc. | Modulation of antibody specificity by tailoring the affinity to cognate antigens |
CA2602035C (en) | 2005-03-18 | 2015-06-16 | Medimmune, Inc. | Framework-shuffling of antibodies |
CN101238145B (zh) | 2005-06-14 | 2013-04-24 | 普罗陶克斯有限公司 | 修饰的成孔蛋白在制备治疗或预防良性前列腺增生的药物中的应用 |
WO2007002543A2 (en) | 2005-06-23 | 2007-01-04 | Medimmune, Inc. | Antibody formulations having optimized aggregation and fragmentation profiles |
AP2008004569A0 (en) * | 2006-02-03 | 2008-08-31 | Imclone Systems Inc | IGR-IR antagonists as adjuvants for treatment of prostrate cancer |
US20080021013A1 (en) * | 2006-07-21 | 2008-01-24 | Cephalon, Inc. | JAK inhibitors for treatment of myeloproliferative disorders |
DK2292663T3 (da) | 2006-08-28 | 2013-11-04 | Kyowa Hakko Kirin Co Ltd | Antagonistiske human-let-specifikke, humane monoklonale antistoffer |
EP2703007A1 (en) | 2007-03-30 | 2014-03-05 | MedImmune, LLC | Antibodies with decreased deamidation profiles |
US20090130195A1 (en) * | 2007-10-17 | 2009-05-21 | Mildred Acevedo-Duncan | Prostate carcinogenesis predictor |
EP2668210B1 (en) | 2011-01-26 | 2020-06-17 | Celldex Therapeutics, Inc. | Anti-kit antibodies and uses thereof |
CA2880007C (en) | 2012-07-25 | 2021-12-28 | Kolltan Pharmaceuticals, Inc. | Anti-kit antibodies and uses thereof |
AU2013329311A1 (en) | 2012-10-09 | 2015-04-30 | Igenica Biotherapeutics, Inc. | Anti-C16orf54 antibodies and methods of use thereof |
EP3003390B1 (en) | 2013-06-06 | 2021-07-07 | Pierre Fabre Médicament | Anti-c10orf54 antibodies and uses thereof |
KR20160054501A (ko) | 2013-08-26 | 2016-05-16 | 맵백스 테라퓨틱스, 인코포레이티드 | 시알릴-루이스 a에 대한 사람 항체 코드화 핵산 |
GB201403775D0 (en) | 2014-03-04 | 2014-04-16 | Kymab Ltd | Antibodies, uses & methods |
CA2950602C (en) | 2014-06-04 | 2021-07-20 | MabVax Therapeutics, Inc. | Human monoclonal antibodies to ganglioside gd2 |
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JP6974178B2 (ja) * | 2015-05-29 | 2021-12-01 | メモリアル スローン ケタリング キャンサー センター | フェロトーシスを介して栄養欠乏がん細胞の細胞死を誘導するための極小ナノ粒子を使用する処置方法 |
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BR112019024717A2 (pt) | 2017-05-25 | 2020-06-09 | Univ Cornell | nanopartículas ultrapequenas marcadas com zircônio-89 e métodos das mesmas |
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JP2020522562A (ja) | 2017-06-06 | 2020-07-30 | ストキューブ アンド シーオー., インコーポレイテッド | Btn1a1又はbtn1a1リガンドに結合する抗体及び分子を用いて癌を治療する方法 |
RU2667906C1 (ru) * | 2017-09-11 | 2018-09-25 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ онкологии им. Н.Н. Блохина" Минздрава России) | Производное класса N-гликозидов индоло[2,3-а]пирроло[3,4-с]карбазол-5,7-дионов - N-{ 12-(β-D-ксилопиранозил)-5,7-диоксо-индоло[2,3-а]пирроло[3,4-с] карбазол-6-ил} пиридин-2-карбоксамид, обладающее цитотоксической и противоопухолевой активностью |
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